| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Pain | D010146 | 64 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Wounds and Injuries | D014947 | 20 associated lipids |
| Burns | D002056 | 34 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Reperfusion Injury | D015427 | 65 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Sarcoma 180 | D012510 | 21 associated lipids |
| Arthritis, Experimental | D001169 | 24 associated lipids |
| Osteoarthritis | D010003 | 4 associated lipids |
| Coronary Disease | D003327 | 70 associated lipids |
| Leukemia, Erythroblastic, Acute | D004915 | 41 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Liver Neoplasms, Experimental | D008114 | 46 associated lipids |
| Lymphoma | D008223 | 18 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Osteoarthritis, Knee | D020370 | 13 associated lipids |
| Brain Edema | D001929 | 20 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gandhi S et al. | PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. | 2009 | Mol. Cell | pmid:19285945 |
| Fang M et al. | Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat. | 2010 | Mol. Cancer | pmid:20704698 |
| Gol'dshteÄn BN et al. | [Kinetic manifestations of the interaction of active centers in swine skeletal muscle D-glyceraldehyde-3-phosphate dehydrogenase]. | 1976 Jan-Feb | Mol. Biol. (Mosk.) | pmid:183104 |
| Lockwood BC et al. | The use of a highly sensitive electrophoretic method to compare the proteinases of trichomonads. | 1987 | Mol. Biochem. Parasitol. | pmid:3302703 |
| Gbenle GO and Akinrimisi EO | Studies on the catalytic properties of the calcium-dependent endoribonuclease of Trypanosoma brucei cytoplasm. | 1982 | Mol. Biochem. Parasitol. | pmid:6178971 |
| Aoki T et al. | Mechanism of inactivation of a Fasciola proteolytic enzyme by peptide aldehydes and alkylating agents. | 1983 | Mol. Biochem. Parasitol. | pmid:6877285 |
| Swamy KH and Jaffe JJ | Isolation, partial purification and some properties of two acid proteases from adult Dirofilaria immitis. | 1983 | Mol. Biochem. Parasitol. | pmid:6366544 |
| North MJ and Coombs GH | Proteinases of Leishmania mexicana amastigotes and promastigotes: analysis by gel electrophoresis. | 1981 | Mol. Biochem. Parasitol. | pmid:7029274 |
| McGaraughty S et al. | TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. | 2010 | Mol Pain | pmid:20205719 |
| Sagar DR et al. | The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain. | 2011 | Mol Pain | pmid:22093915 |
| Rahman W et al. | Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain. | 2009 | Mol Pain | pmid:19664204 |
| Harvey VL and Dickenson AH | Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice. | 2009 | Mol Pain | pmid:19379487 |
| Neugebauer V et al. | Techniques for assessing knee joint pain in arthritis. | 2007 | Mol Pain | pmid:17391515 |
| Abaei M et al. | Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain. | 2016 | Mol Pain | pmid:27068285 |
| Lee Y et al. | Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord. | 2011 | Mol Pain | pmid:21599960 |
| Ferreira-Gomes J et al. | Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat. | 2012 | Mol Pain | pmid:22769424 |
| Sweet C and Halliwell G | Regulation of cellvibriocin activity. | 1977 | Microbios | pmid:617829 |
| el-Rahmany TA | Comparison of L-aspartate 4-carboxy-lyases of Cunninghamella elegans and Penicillium citrinum. | 1994 | Microbiol. Res. | pmid:7987614 |
| Sakurai J et al. | Effect of oxidizing agents and sulfhydryl group reagents on beta toxin from Clostridium perfringens type C. | 1980 | Microbiol. Immunol. | pmid:6251344 |
| Yoshimura G et al. | Identification and molecular characterization of an N-Acetylmuraminidase, Aml, involved in Streptococcus mutans cell separation. | 2006 | Microbiol. Immunol. | pmid:16985295 |
| Carne AF and U S | Chemical modification of proteins for sequence analysis. | 1997 | Methods Mol. Biol. | pmid:9116830 |
| Meng TC et al. | Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo. | 2005 | Methods | pmid:15588983 |
| Creighton TE | Disulfide bond formation in proteins. | 1984 | Meth. Enzymol. | pmid:6503716 |
| Inglis AS | Single hydrolysis method for all amino acids, including cysteine and tryptophan. | 1983 | Meth. Enzymol. | pmid:6855579 |
| Kimura M et al. | Detection of carboxymethylmetallothionein by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. | 1991 | Meth. Enzymol. | pmid:1779774 |
| Thomas JA et al. | Analysis of cells and tissues for S-thiolation of specific proteins. | 1995 | Meth. Enzymol. | pmid:7651223 |
| Dalal P and Romani A | Adenosine triphosphate depletion by cyanide results in a Na(+)-dependent Mg(2+) extrusion from liver cells. | 2010 | Metab. Clin. Exp. | pmid:20494376 |
| Shiroyama K et al. | Glucose loading during primary culture has opposite effects on the viability of hepatocytes exposed to potassium cyanide and to iodoacetic acid. | 2001 | Metab. Clin. Exp. | pmid:11230789 |
| Young EF et al. | Structural characterization of phospholamban in cardiac sarcoplasmic reticulum membranes by cross-linking. | 1989 | Membr Biochem | pmid:2634236 |
| Sixt SU et al. | Distinct proteasome subpopulations in the alveolar space of patients with the acute respiratory distress syndrome. | 2012 | Mediators Inflamm. | pmid:22363101 |
| D'Onofrio C et al. | The influence of some metabolic inhibitors on in vitro phagocytizing macrophages. I. The behaviour of human macrophages. | 1977 | Med. Microbiol. Immunol. | pmid:916975 |
| Dhaneshwar S and Patil D | Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia. | 2013 | Med Chem | pmid:22920092 |
| Barry AC et al. | Protective effect of glucose on the anoxic myocardium of old and young mice. | 1987 | Mech. Ageing Dev. | pmid:3695592 |
| Veneziale CM and Swenson RP | Gluconeogenesis in isolated hepatic parenchymal cells. VII. Effects of monobutyryl cyclic adenosine monophosphate on gluconeogenic intermediates, phosphofructokinase, and fructose diphosphatase. | 1975 | Mayo Clin. Proc. | pmid:165334 |
| Zakrzewska I et al. | Low molecular organic inactivators in differentiating organ origin of alpha-amylase in humans. Part I. | 1989 Oct-Dec | Mater Med Pol | pmid:2518736 |
| Damon BM et al. | The carnosine C-2 proton's chemical shift reports intracellular pH in oxidative and glycolytic muscle fibers. | 2003 | Magn Reson Med | pmid:12541242 |
| Stewart LC et al. | Simultaneous measurement of both lipid and lactate in isolated rat hearts by 1H NMR spectroscopy. | 1993 | Magn Reson Med | pmid:8139446 |
| Battista N et al. | Anandamide uptake by synaptosomes from human, mouse and rat brain: inhibition by glutamine and glutamate. | 2002 | Lipids Health Dis | pmid:12617751 |
| Gibson DD et al. | GSH-dependent inhibition of lipid peroxidation: properties of a potent cytosolic system which protects cell membranes. | 1985 | Lipids | pmid:4058268 |
| Kawanishi T et al. | Suppression of Na+ influx in ATP-depleted hepatocytes. | 1995 | Life Sci. | pmid:7603308 |
| Bartha E et al. | Molecular form of human lymphocyte membrane-bound acetylcholinesterase. | 1987 | Life Sci. | pmid:3657387 |
| Yang NC et al. | ATP depletion is an important factor in DHEA-induced growth inhibition and apoptosis in BV-2 cells. | 2002 | Life Sci. | pmid:12148690 |
| Turkelson CM | Effects of ATP synthesis inhibitors, temperature, 8-bromo c-AMP, and calcium omission on release of corticotropin releasing factor from superfused rat hypothalami. | 1988 | Life Sci. | pmid:3262804 |
| Takaoka M et al. | Activation of urinary inactive kallikrein by an extract from the rat kidney cortex. | 1985 | Life Sci. | pmid:3897754 |
| Kagawa S et al. | Development and function of B cells in monolayer islet cells of 3-week-old rat. | 1987 | Life Sci. | pmid:2444853 |
| Smit V | In vitro suppression of leukemia by alkylated interleukin-3. | 1995 | Leukemia | pmid:7769858 |
| Gill DS and Wickramasinghe SN | Observations on the intracellular accumulation of methotrexate and 5-methyltetrahydrofolate in uninduced, dimethylsulphoxide-induced and 1,25-dihydroxyvitamin D3-induced HL60 cells, and blood-monocyte-derived human macrophages. | 1988 | Leuk. Res. | pmid:2833665 |
| Phelps PC et al. | Cytosolic ionized calcium and bleb formation after acute cell injury of cultured rabbit renal tubule cells. | 1989 | Lab. Invest. | pmid:2654473 |
| Cazenave JP et al. | Effects of sodium periodate on platelet functions. | 1976 | Lab. Invest. | pmid:178961 |
| Rogers AB et al. | Thiol-reactive compounds prevent nonspecific antibody binding in immunohistochemistry. | 2006 | Lab. Invest. | pmid:16534499 |
| Buja LM et al. | Alterations of ultrastructure and elemental composition in cultured neonatal rat cardiac myocytes after metabolic inhibition with iodoacetic acid. | 1985 | Lab. Invest. | pmid:2413276 |
| McArthur W et al. | Bone solubilization by mononuclear cells. | 1980 | Lab. Invest. | pmid:7374109 |
| Noda K | Possible mechanism for producing enhanced 45 Ca ion release from the muscle membrane in the presence of iodoacetate. | 1971 | Kurume Med J | pmid:5211565 |
| Lee SJ et al. | Alterations in membrane transport function and cell viability induced by ATP depletion in primary cultured rabbit renal proximal tubular cells. | 2009 | Korean J. Physiol. Pharmacol. | pmid:19885021 |
| Choi MH et al. | Purification of a 68-kDa cysteine proteinase from crude extract of Pneumocystis carinii. | 2000 | Korean J. Parasitol. | pmid:11002651 |
| Chung YB et al. | Partial characterization of a 17 kDa protein of Clonorchis sinensis. | 2000 | Korean J. Parasitol. | pmid:10905071 |
| Kim JY et al. | Partial characterization of a 29 kDa cysteine protease purified from Taenia solium metacestodes. | 2005 | Korean J. Parasitol. | pmid:16340305 |
| KOHLER V and SCHARF J | [Importance of metabolic processes sensitive to mono-iodoacetic acid for tissue inflammation]. | 1951 | Klin. Wochenschr. | pmid:14825752 |
| Somerville PJ and Kaye M | Action of phosphorus on calcium release in isolated perfused rat tails. | 1982 | Kidney Int. | pmid:6294399 |
| Sorimachi M and Nishimura S | A small increment of external K concentration accelerates adrenomedullary catecholamine secretion induced by ouabain and metabolic inhibitors. | 1983 | Jpn. J. Physiol. | pmid:6315998 |
| Kuwata K et al. | Cross-relaxation times of normal and biochemically induced osteoarthritic rabbit knee cartilages. | 1997 | Jpn. J. Physiol. | pmid:9271160 |
| Yoshizaki K et al. | Intracellular pH measurement in frog muscle by means of 31P-nuclear magnetic resonance. | 1979 | Jpn. J. Physiol. | pmid:40052 |
| Fukuda H and Kontani H | Effects of metabolic inhibitors and ouabain on static afferent discharges from the isolated frog muscle spindle. | 1976 | Jpn. J. Pharmacol. | pmid:1088168 |
| Kishi M et al. | Pharmacological characteristics of choline transport system in mouse cerebral cortical neurons in primary culture. | 1991 | Jpn. J. Pharmacol. | pmid:2067141 |
| Yamamoto K et al. | Characteristics of activation of cathepsin B by sodium salicylate and comparison of catalytic site properties of cathepsins B and H. | 1985 | Jpn. J. Pharmacol. | pmid:4087567 |
| Nasu T et al. | Role of glycolysis in the tension development under anoxia in guinea pig taenia coli. | 1982 | Jpn. J. Pharmacol. | pmid:7087264 |
| Chhatwal GS and Gaitonde BB | Purification of a nontoxic phospholipase A2 from the venom of Indian krait (Bungarus caeruleus). | 1978 | Jpn. J. Med. Sci. Biol. | pmid:32414 |
| Narita H et al. | Ischemia-reperfusion induced elevation of diastolic tension in the isolated guinea pig heart and the effects of calcium antagonists. | 1983 | Jpn Heart J | pmid:6854962 |
| Shangraw RE and Turinsky J | Local response of muscle to burns: relationship of glycolysis and amino acid release. | 1981 May-Jun | JPEN J Parenter Enteral Nutr | pmid:7195947 |
| Matsuki N et al. | Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia. | 2002 | J. Vet. Med. Sci. | pmid:12014580 |
| Kaneda T et al. | Key role of glycogen storage in high K+-induced contraction of the smooth muscles of the bovine trachea. | 2012 | J. Vet. Med. Sci. | pmid:22673054 |
| Kahlenberg A and Zala CA | Reconstitution of D-glucose transport in vesicles composed of lipids and intrinsic protein (zone 4.5) of the human erythrocyte membrane. | 1977 | J. Supramol. Struct. | pmid:616483 |
| Phillips ER and Perdue JF | The expression and localization of surface neoantigens in transformed and untransformed cultured cells infected with avian tumor viruses. | 1976 | J. Supramol. Struct. | pmid:1256061 |
| Bárány M et al. | Structural changes in myosin during contraction and the state of ATP in the intact frog muscle. | 1975 | J. Supramol. Struct. | pmid:127883 |
| Silva CM and Cidlowski JA | The effect of oxidation/reduction on the charge heterogeneity of the human glucocorticoid receptor. | 1992 | J. Steroid Biochem. Mol. Biol. | pmid:1734932 |
| Yang R et al. | Partial purification and characterisation of cysteine protease in wheat germ. | 2011 | J. Sci. Food Agric. | pmid:21702054 |
| Nagarathnam R et al. | Purification and properties of cysteine protease from rhizomes of Curcuma longa (Linn.). | 2010 | J. Sci. Food Agric. | pmid:20355018 |
| Kalbhen DA | Chemical model of osteoarthritis--a pharmacological evaluation. | 1987 | J. Rheumatol. | pmid:3625668 |
| Williams JM and Brandt KD | Benoxaprofen reduces osteophyte formation and fibrillation after articular cartilage injury. | 1985 | J. Rheumatol. | pmid:3981515 |
| van Osch GJ et al. | Site specific inhibition of cartilage proteoglycan synthesis in the murine knee joint. Differences between 3 metabolic stimuli. | 1994 | J. Rheumatol. | pmid:7932423 |
| Loeuille D et al. | In vitro magnetic resonance microimaging of experimental osteoarthritis in the rat knee joint. | 1997 | J. Rheumatol. | pmid:9002024 |
| Lepley PR and Mukkada AJ | Characteristics of an uptake system for alpha-aminoisobutyric acid in Leishmania tropica promastigotes. | 1983 | J. Protozool. | pmid:6864594 |
| Wang H et al. | Proteomic analysis of early-responsive redox-sensitive proteins in Arabidopsis. | 2012 | J. Proteome Res. | pmid:22050424 |
| Lin D et al. | Cysteinyl peptide capture for shotgun proteomics: global assessment of chemoselective fractionation. | 2010 | J. Proteome Res. | pmid:20731415 |
| Denton ME and Scheraga HA | Spectroscopic, immunochemical, and thermodynamic properties of carboxymethyl(Cys6, Cys127)-hen egg white lysozyme. | 1991 | J. Protein Chem. | pmid:1930635 |
| Kohanski RA and Heinrikson RL | Primary structure of avian hepatic rhodanese. | 1990 | J. Protein Chem. | pmid:2275748 |
| Batra PP et al. | Circular dichroic study of conformational changes in ovalbumin induced by modification of sulfhydryl groups and disulfide reduction. | 1989 | J. Protein Chem. | pmid:2610856 |
| Lehner C et al. | Nitric oxide suppresses growth and development in the unicellular green alga Micrasterias denticulata. | 2009 | J. Plant Physiol. | pmid:18455833 |
| Thibert P and Nicolet M | [Tetanic fatigue and proximate post-tetanic recuperation in sartorius and flexor carpi radialis muscles of the male frog. Effects of iodoacetic acid (author's transl)]. | 1976 | J. Physiol. (Paris) | pmid:1083432 |
| Fink R and Lüttgau HC | An evaluation of the membrane constants and the potassium conductance in metabolically exhausted muscle fibres. | 1976 | J. Physiol. (Lond.) | pmid:1087932 |
| de Hemptinne A and Huguenin F | The influence of muscle respiration and glycolysis on surface and intracellular pH in fibres of the rat soleus. | 1984 | J. Physiol. (Lond.) | pmid:6707968 |
| Mulvany MJ | Mechanical properties of frog skeletal muscles in iodoacetic acid rigor. | 1975 | J. Physiol. (Lond.) | pmid:1082023 |
| Ingram KR et al. | Cyclic movement stimulates hyaluronan secretion into the synovial cavity of rabbit joints. | 2008 | J. Physiol. (Lond.) | pmid:18202097 |
| Zima AV et al. | Cytosolic energy reserves determine the effect of glycolytic sugar phosphates on sarcoplasmic reticulum Ca2+ release in cat ventricular myocytes. | 2006 | J. Physiol. (Lond.) | pmid:16945967 |
| Blendstrup K et al. | Characteristics of renin release from isolated superfused glomeruli in vitro. | 1975 | J. Physiol. (Lond.) | pmid:1133791 |
| Fischbarg J and Lim JJ | Role of cations, anions and carbonic anhydrase in fluid transport across rabbit corneal endothelium. | 1974 | J. Physiol. (Lond.) | pmid:4215880 |
| Kirpekar SM et al. | Metabolic and ionic requirements for the intra-axonal transport of noradrenaline in the cat hypogastric nerve. | 1973 | J. Physiol. (Lond.) | pmid:4119622 |
| Nakayama S et al. | Consequences of metabolic inhibition in smooth muscle isolated from guinea-pig stomach. | 1997 | J. Physiol. (Lond.) | pmid:9409485 |
| Hogg RC and Adams DJ | An ATP-sensitive K(+) conductance in dissociated neurones from adult rat intracardiac ganglia. | 2001 | J. Physiol. (Lond.) | pmid:11483702 |
| Smith GL et al. | Relationship between intracellular pH and metabolite concentrations during metabolic inhibition in isolated ferret heart. | 1993 | J. Physiol. (Lond.) | pmid:8145137 |