Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Villalba JM et al. Thiol groups are involved in NADH-ascorbate free radical reductase activity of rat liver plasma membrane. 1993 Biochem. Biophys. Res. Commun. pmid:8484777
Kaloyianni M et al. Effect of adenosine on glucose metabolism of Rana ridibunda erythrocytes. 1993 J. Exp. Biol. pmid:8487000
Yamada T et al. 31P nuclear magnetic resonance studies on the glycogenolysis regulation in resting and contracting frog skeletal muscle. 1993 J. Physiol. (Lond.) pmid:8487196
Chen LY et al. Deoxyribonuclease of Syncephalastrum racemosum--enzymatic properties and molecular structure. 1993 Arch. Biochem. Biophys. pmid:8489265
Maublant JC et al. Uptake of technetium-99m-teboroxime in cultured myocardial cells: comparison with thallium-201 and technetium-99m-sestamibi. 1993 J. Nucl. Med. pmid:8429344
Park YC and Goodman WG Analysis and modification of thiols in the hemolymph juvenile hormone binding protein of Manduca sexta. 1993 Arch. Biochem. Biophys. pmid:8470889
Brooks SP and Storey KB Control of glycolytic enzyme binding: effect of changing enzyme substrate concentrations on in vivo enzyme distributions. 1993 Mol. Cell. Biochem. pmid:8350861
Bickler PE et al. Developmental changes in intracellular calcium regulation in rat cerebral cortex during hypoxia. 1993 J. Cereb. Blood Flow Metab. pmid:8103057
Stewart LC et al. Simultaneous measurement of both lipid and lactate in isolated rat hearts by 1H NMR spectroscopy. 1993 Magn Reson Med pmid:8139446
Smith GL et al. Relationship between intracellular pH and metabolite concentrations during metabolic inhibition in isolated ferret heart. 1993 J. Physiol. (Lond.) pmid:8145137
Roberts EL Glycolysis and recovery of potassium ion homeostasis and synaptic transmission in hippocampal slices after anoxia or stimulated potassium release. 1993 Brain Res. pmid:8396493
Suzuki R and Anderson PJ A temperature dependent action of fluoride on aqueous outflow facility of the calf eye. 1993 Curr. Eye Res. pmid:8436006
Salamino F et al. Site-directed activation of calpain is promoted by a membrane-associated natural activator protein. 1993 Biochem. J. pmid:8439288
Dunham J et al. Prolonged effect of iodoacetate on articular cartilage and its modification by an anti-rheumatic drug. 1993 Int J Exp Pathol pmid:8334078
van Osch GJ et al. In vivo quantification of proteoglycan synthesis in articular cartilage of different topographical areas in the murine knee joint. 1993 J. Orthop. Res. pmid:8340822
Liu SQ et al. Identification of the reactive cysteine residue in human placenta aldose reductase. 1993 Biochim. Biophys. Acta pmid:8343525
Sethi R et al. Characteristics and mechanisms of tachyphylaxis of cardiac contractile response to insulin. 1993 Int. J. Cardiol. pmid:8454373
Sun FF et al. Degradation of membrane phospholipids in the cultured human astroglial cell line UC-11MG during ATP depletion. 1993 Biochem. Pharmacol. pmid:8461044
Oleinikov AV et al. Structural and functional domains of Escherichia coli ribosomal protein L7/L12. The hinge region is required for activity. 1993 J. Biol. Chem. pmid:8419370
Lewis CT et al. Identification of vicinal thiols of phosphoenolpyruvate carboxykinase (GTP). 1993 J. Biol. Chem. pmid:8420937
Nakamura K et al. Glycolysis is necessary to preserve myocardial Ca2+ homeostasis during beta-adrenergic stimulation. 1993 Am. J. Physiol. pmid:8384419
Perks AM et al. Reabsorption of lung liquid produced by 2,4-dinitrophenol in in vitro lungs from fetal guinea pigs. 1993 Can. J. Physiol. Pharmacol. pmid:8390326
Kaur S et al. Effect of pH and sodium ions on intestinal uptake of lysine in rats. 1993 Indian J. Exp. Biol. pmid:8406600
Madl JE and Burgesser K Adenosine triphosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices. 1993 J. Neurosci. pmid:8105040
Guiraud P et al. Cultured human skin fibroblasts absorb 65Zn. Optimization of the method and study of the mechanisms involved. 1992 Jan-Mar Biol Trace Elem Res pmid:1375058
Hoskins IA et al. Use of esterase inhibitors and zone electrophoresis to define bacterial esterases in amniotic fluid. 1992 Am. J. Obstet. Gynecol. pmid:1471669
Chang TK and Cheng JT Inhibitory effect of xylamine on the uptake of [3H]norepinephrine into primary astrocyte cultures. 1992 Brain Res. pmid:1477731
Kamendulis LM and Corcoran GB Independence and additivity of cultured hepatocyte killing by Ca2+ overload and ATP depletion. 1992 Toxicol. Lett. pmid:1488777
Gustafson SB et al. Evaluation of intra-articularly administered sodium monoiodoacetate-induced chemical injury to articular cartilage of horses. 1992 Am. J. Vet. Res. pmid:1497191
Andersen BJ and Marmarou A Functional compartmentalization of energy production in neural tissue. 1992 Brain Res. pmid:1511302
Dunham J et al. Structural and metabolic changes in articular cartilage induced by iodoacetate. 1992 Int J Exp Pathol pmid:1390193
Cummings JG et al. Reductive half-reaction in medium-chain acyl-CoA dehydrogenase: modulation of internal equilibrium by carboxymethylation of a specific methionine residue. 1992 Biochemistry pmid:1390638
Adams EM et al. Lack of [3H]quinuclidinyl benzylate binding to biologically relevant binding sites on mononuclear cells. 1992 Brain Behav. Immun. pmid:1392105
Furukawa N et al. [A biochemical study of an animal model with defective muscle glycolysis, induced by iodoacetate administration]. 1992 No To Hattatsu pmid:1520510
Notsu T et al. Blockade of the ATP-sensitive K+ channel by 5-hydroxydecanoate in guinea pig ventricular myocytes. 1992 J. Pharmacol. Exp. Ther. pmid:1738118
Plishker GA et al. Calcium-activated potassium transport and high molecular weight forms of calpromotin. 1992 J. Biol. Chem. pmid:1400494
Greenhalgh DA et al. Effect of introducing different carboxylate-containing side chains at position 85 on chromophore formation and proton transport in bacteriorhodopsin. 1992 J. Biol. Chem. pmid:1361187
Kempski O et al. Swelling of C6 glioma cells and astrocytes from glutamate, high K+ concentrations or acidosis. 1992 Prog. Brain Res. pmid:1363149
Imberti R et al. Synergism of cyclosporin A and phospholipase inhibitors in protection against lethal injury to rat hepatocytes from oxidant chemicals. 1992 Res. Commun. Chem. Pathol. Pharmacol. pmid:1462047
Bickler PE and Kelleher JA Fructose-1,6-bisphosphate stabilizes brain intracellular calcium during hypoxia in rats. 1992 Stroke pmid:1440710
Raffin CN et al. Glycolysis, oxidative metabolism, and brain potassium ion clearance. 1992 J. Cereb. Blood Flow Metab. pmid:1727141
Pot DA and Dixon JE Active site labeling of a receptor-like protein tyrosine phosphatase. 1992 J. Biol. Chem. pmid:1730581
Buttle DJ et al. Inhibition of interleukin 1-stimulated cartilage proteoglycan degradation by a lipophilic inactivator of cysteine endopeptidases. 1992 Biochem. J. pmid:1731753
Silva CM and Cidlowski JA The effect of oxidation/reduction on the charge heterogeneity of the human glucocorticoid receptor. 1992 J. Steroid Biochem. Mol. Biol. pmid:1734932
Zhang ZY et al. Covalent modification and active site-directed inactivation of a low molecular weight phosphotyrosyl protein phosphatase. 1992 Biochemistry pmid:1737025
Silberberg SD and van Breemen C A potassium current activated by lemakalim and metabolic inhibition in rabbit mesenteric artery. 1992 Pflugers Arch. pmid:1553259
Parfett CL Induction of proliferin gene expression by diverse chemical agents that promote morphological transformation in C3H/10T1/2 cultures. 1992 Cancer Lett. pmid:1596871
Sorrentino S et al. Eosinophil-derived neurotoxin and human liver ribonuclease. Identity of structure and linkage of neurotoxicity to nuclease activity. 1992 J. Biol. Chem. pmid:1634526
Brecht M et al. Late steady increase in cytosolic Ca2+ preceding hypoxic injury in hepatocytes. 1992 Biochem. J. pmid:1575684
Liu SQ et al. Carboxymethylation-induced activation of bovine lens aldose reductase. 1992 Biochim. Biophys. Acta pmid:1576159
Kuzminskaya EV et al. Rabbit muscle D-glyceraldehyde-3-phosphate dehydrogenase: half-of-the-sites reactivity of the enzyme modified at arginine residues. 1992 Biochem. Biophys. Res. Commun. pmid:1530616
Bobilya DJ et al. Zinc transport into endothelial cells is a facilitated process. 1992 J. Cell. Physiol. pmid:1560036
Osbakken M et al. Isolated cardiomyocytes in conjunction with NMR spectroscopy techniques to study metabolism and ion flux. 1992 J. Biol. Chem. pmid:1639780
Zeevalk GD and Nicklas WJ NMDA receptors, cellular edema, and metabolic stress. 1992 Ann. N. Y. Acad. Sci. pmid:1353336
Milne KG et al. Inhibition of the GlcNAc transferase of the glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes. 1992 Eur. J. Biochem. pmid:1325903
Siksnys V and Pleckaityte M Role of the reactive cysteine residue in restriction endonuclease Cfr9I. 1992 Biochim. Biophys. Acta pmid:1332782
Lucas J et al. Susceptibility of myelin proteins to a neutral endoproteinase: the degradation of myelin basic protein (MBP) and P2 protein by purified bovine brain multicatalytic proteinase complex (MPC). 1992 Neurochem. Res. pmid:1281293
Rosenthal M and Sick TJ Glycolytic and oxidative metabolic contributions to potassium ion transport in rat cerebral cortex. 1992 Can. J. Physiol. Pharmacol. pmid:1295667
Hruz PW and Miziorko HM Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines. 1992 Protein Sci. pmid:1304393
Xia Y et al. Oxidative and glycolytic pathways in rat (newborn and adult) and turtle brain: role during anoxia. 1992 Am. J. Physiol. pmid:1314516
Stinson MW et al. Inhibition of Porphyromonas gingivalis adhesion to Streptococcus gordonii by human submandibular-sublingual saliva. 1992 Infect. Immun. pmid:1319402
Knowles MR et al. Bovine inositol monophosphatase. Modification, identification and mutagenesis of reactive cysteine residues. 1992 Biochem. J. pmid:1322134
Mejía-Alvarez R and Marban E Mechanism of the increase in intracellular sodium during metabolic inhibition: direct evidence against mediation by voltage-dependent sodium channels. 1992 J. Mol. Cell. Cardiol. pmid:1336064
Lin YJ et al. Disulfide-linked and noncovalent dimers of p185HER-2 in human breast carcinoma cells. 1992 J. Cell. Biochem. pmid:1379605
Lee GF and Anderson DC Reversed-phase high-pressure liquid chromatographic tryptic peptide mapping for the comparison and study of monoclonal antibodies. 1991 Sep-Oct Bioconjug. Chem. pmid:1790177
Candy TE et al. Estimation of tyrosine by the attenuation of 4-iodophenol enhanced chemiluminescence. 1991 Oct-Dec J. Biolumin. Chemilumin. pmid:1792937
Ataman OV [Ectonucleotidase activity of isolated strips of arteries and veins of experimental animals. Influence of various damaging agents on ecto-ATPase activity of blood vessels]. 1991 Nov-Dec Fiziol Zh pmid:1668200
Buja LM et al. Altered membrane fluidity occurs during metabolic impairment of cardiac myocytes. 1991 May-Jun In Vivo pmid:1893080
Van Tol A et al. Net mass transfer of cholesteryl esters from low density lipoproteins to high density lipoproteins in plasma from normolipidemic subjects. 1991 Jan-Feb Arterioscler. Thromb. pmid:1988004
Balhorn R et al. Identification of bull protamine disulfides. 1991 Biochemistry pmid:1988019
Hawkins HC et al. Redox properties and cross-linking of the dithiol/disulphide active sites of mammalian protein disulphide-isomerase. 1991 Biochem. J. pmid:2025221
Denton ME and Scheraga HA Spectroscopic, immunochemical, and thermodynamic properties of carboxymethyl(Cys6, Cys127)-hen egg white lysozyme. 1991 J. Protein Chem. pmid:1930635
Oreffo VI et al. Diamine uptake by rat lung type II cells in vitro. 1991 Biochem. Pharmacol. pmid:2009096
Spencer P et al. The identification of a structurally important cysteine residue in the glycerol dehydrogenase from Bacillus stearothermophilus. 1991 Biochim. Biophys. Acta pmid:2009285
Florine-Casteel K et al. Lipid order in hepatocyte plasma membrane blebs during ATP depletion measured by digitized video fluorescence polarization microscopy. 1991 FASEB J. pmid:2010060
Cannon JR et al. The effects of fructose on adenosine triphosphate depletion following mitochondrial dysfunction and lethal cell injury in isolated rat hepatocytes. 1991 Toxicol. Appl. Pharmacol. pmid:2020968
Armstrong SC and Ganote CE Effects of the phospholipase inhibitor mepacrine on injury in ischemic and metabolically inhibited adult isolated myocytes. 1991 Am. J. Pathol. pmid:2000934
Kempson SA et al. Iodoacetate action on endocytic uptake of different fluid-phase markers by OK renal epithelial cells. 1991 Biochim. Biophys. Acta pmid:2001415
Konishi K and Fujioka M Reversible inactivation of recombinant rat liver guanidinoacetate methyltransferase by glutathione disulfide. 1991 Arch. Biochem. Biophys. pmid:1898065
Lees GJ and Sandberg M Evoked field potential changes in the rat hippocampus produced by toxic doses of glutamate agonists and metabolic inhibitors: correlation with subsequent neuronal death. 1991 Exp Brain Res pmid:1680739
Faix S et al. Micropuncture study of the kidney in sheep: effects of iodoacetate on renal urea handling. 1991 Comp Biochem Physiol A Comp Physiol pmid:1682092
Baker MS et al. Oxidation of articular cartilage glyceraldehyde-3-phosphate dehydrogenase (G3PDH) occurs in vivo during carrageenin-induced arthritis. 1991 Agents Actions pmid:1862748
Weinberg JM et al. Metabolic aspects of protection by glycine against hypoxic injury to isolated proximal tubules. 1991 J. Am. Soc. Nephrol. pmid:1883965
Kishi M et al. Pharmacological characteristics of choline transport system in mouse cerebral cortical neurons in primary culture. 1991 Jpn. J. Pharmacol. pmid:2067141
Kembhavi AA et al. Clostripain: characterization of the active site. 1991 FEBS Lett. pmid:2044766
Harrison DC et al. A pH-dependent phospholipase A2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes. 1991 Biochem. Biophys. Res. Commun. pmid:1899571
Ozaki K and Ito S Purification and properties of an acid endo-1,4-beta-glucanase from Bacillus sp. KSM-330. 1991 J. Gen. Microbiol. pmid:2045781
Keough DT et al. Localization of the 5-phospho-alpha-D-ribosyl-1-pyrophosphate binding site of human hypoxanthine-guanine phosphoribosyltransferase. 1991 Biochim. Biophys. Acta pmid:1705826
Novak M et al. Mesocestoides corti: a GC/MS study of the effects of oxaloacetate and iodoacetate on the isotope ratios in succinate and lactate excreted in the presence of NaH13CO3. 1991 Exp. Parasitol. pmid:1847107
Zeevalk GD and Nicklas WJ Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition. 1991 J. Pharmacol. Exp. Ther. pmid:1851840
Perks AM et al. Lung liquid production by in vitro lungs from fetal guinea pigs: studies with metabolic inhibitors. 1991 Can. J. Physiol. Pharmacol. pmid:1756423
Li W and Stanley ER Role of dimerization and modification of the CSF-1 receptor in its activation and internalization during the CSF-1 response. 1991 EMBO J. pmid:1825054
Tóth G and Szabó G Nucleotide and DNA uptake by Neurospora crassa: involvement of an uptake stimulating protein. 1991 Biochim. Biophys. Acta pmid:1826455
Saha N and Samuel AP Characterization of glucose-6-phosphate dehydrogenase variants in the Sudan--including GdKhartoum, a hyperactive slow variant. 1991 Hum. Hered. pmid:1828777
Chen CY et al. Inactivation of chicken mitochondrial phosphoenolpyruvate carboxykinase by o-phthalaldehyde. 1991 J. Biol. Chem. pmid:1885594
Lo RS et al. An endogenous carrier-mediated uptake system for folate in oocytes of Xenopus laevis. 1991 Proc. Biol. Sci. pmid:1685241
Nasu T et al. Changes in K(+)-induced contractions in ileal longitudinal smooth muscle of guinea-pig, induced by monoiodoacetic acid. 1991 J. Pharm. Pharmacol. pmid:1685528
Verity MA et al. Paradoxical potentiation by low extracellular Ca2+ of acute chemical anoxic neuronal injury in cerebellar granule cell culture. 1991 Mol. Chem. Neuropathol. pmid:1687239
Wagner J and Mutus B Transient activation of calcineurin during thiol modification. 1991 Second Messengers Phosphoproteins pmid:1667419
Marlewski M et al. Adenine nucleotide catabolism in the erythrocytes of uraemic patients. 1991 Adv. Exp. Med. Biol. pmid:1781394