Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Rigor Mortis D012298 1 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteophyte D054850 2 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
Muscle Cramp D009120 3 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Osteoarthritis D010003 4 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Retinitis D012173 4 associated lipids
Thrombophilia D019851 6 associated lipids
Rickets D012279 6 associated lipids
Blindness D001766 6 associated lipids
Theileriasis D013801 7 associated lipids
Arthralgia D018771 8 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Byssinosis D002095 11 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Hypocalcemia D006996 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thrombocytopenia D013921 15 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Lymphoma D008223 18 associated lipids
Brain Edema D001929 20 associated lipids
Wounds and Injuries D014947 20 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Stroke D020521 32 associated lipids
Burns D002056 34 associated lipids
Epilepsy D004827 35 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Starvation D013217 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nerve Degeneration D009410 53 associated lipids
Pain D010146 64 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Brain Ischemia D002545 89 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Okamura-Ikeda K et al. An essential cysteine residue located in the vicinity of the FAD-binding site in short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. 1985 J. Biol. Chem. pmid:3968065
Abrahamsen J and Nedergaard OA Accumulation of 3H-adrenaline by rabbit aorta. 1985 Blood Vessels pmid:3967097
Gupta NK and Glantz MD Isolation and characterization of human liver guanine deaminase. 1985 Arch. Biochem. Biophys. pmid:3966794
Hashimoto K et al. Iodoacetylated and biotinylated liposomes: effect of spacer length on sulfhydryl ligand binding and avidin precipitability. 1986 Biochim. Biophys. Acta pmid:3964696
Kuwabara T et al. 31P-NMR studies on an animal model of human defective muscle glycolysis. 1986 Muscle Nerve pmid:3951487
King MM Modification of the calmodulin-stimulated phosphatase, calcineurin, by sulfhydryl reagents. 1986 J. Biol. Chem. pmid:3949803
Tompa P et al. The phosphate group of 3-phosphoglycerate accounts for conformational changes occurring on binding to 3-phosphoglycerate kinase. Enzyme inhibition and thiol reactivity studies. 1986 Eur. J. Biochem. pmid:3948871
Hilf R et al. Relationship of mitochondrial function and cellular adenosine triphosphate levels to hematoporphyrin derivative-induced photosensitization in R3230AC mammary tumors. 1986 Cancer Res. pmid:3940191
Chien KR et al. Release of arachidonate from membrane phospholipids in cultured neonatal rat myocardial cells during adenosine triphosphate depletion. Correlation with the progression of cell injury. 1985 J. Clin. Invest. pmid:3924955
Montanaro L et al. A metalloproteinase associated with gelonin, a "ribosome inactivating protein". 1985 Jan-Feb Ital. J. Biochem. pmid:3924857
Baskova IP and Nikonov GI [Destabilase: an enzyme of medicinal leech salivary gland secretion hydrolyzes the isopeptide bonds in stabilized fibrin]. 1985 Biokhimiia pmid:3922436
Hardy MA and Ware HM Roles of Ca2+ and Na+ on the modulation of antidiuretic hormone action on urea permeability in toad urinary bladder. 1985 J. Clin. Invest. pmid:3920247
Kirley JW and Day RA Irreversible inhibition of carbonic anhydrase by the carbon dioxide analog cyanogen. 1985 Biochem. Biophys. Res. Commun. pmid:3918532
Wakade AR et al. Sympathetic neurons extend neurites in a culture medium containing cyanide and dinitrophenol but not iodoacetate. 1985 FEBS Lett. pmid:3899726
Takaoka M et al. Activation of urinary inactive kallikrein by an extract from the rat kidney cortex. 1985 Life Sci. pmid:3897754
Bühler R et al. Human liver alcohol dehydrogenase: the unique properties of the "atypical" isoenzyme beta 2 beta 2-Bern can be explained by a single base mutation. 1985 Jan-Feb Alcohol pmid:3893464
Seliuchenko OA et al. [Topography of cysteine residues in DNA-dependent RNA-polymerase]. 1985 Bioorg. Khim. pmid:3890863
Stewart LM et al. Energy coupling to K+ uptake via the Trk system in Escherichia coli: the role of ATP. 1985 J. Gen. Microbiol. pmid:3886836
Nakamura CE and Abeles RH Mode of interaction of beta-hydroxy-beta-methylglutaryl coenzyme A reductase with strong binding inhibitors: compactin and related compounds. 1985 Biochemistry pmid:3886005
Bosron WF et al. Purification and characterization of human liver beta 1 beta 1, beta 2 beta 2 and beta Ind beta Ind alcohol dehydrogenase isoenzymes. 1985 Prog. Clin. Biol. Res. pmid:3885259
Morgan MS et al. Participation of cellular thiol/disulphide groups in the uptake, degradation and bioactivity of insulin in primary cultures of rat hepatocytes. 1985 Biochem. J. pmid:3883990
Shroyer LA and Varandani PT Purification and characterization of a rat liver cytosol neutral thiol peptidase that degrades glucagon, insulin, and isolated insulin A and B chains. 1985 Arch. Biochem. Biophys. pmid:3881083
Norris SH and Hersey SJ Stimulation of pepsinogen secretion in permeable isolated gastric glands. 1985 Am. J. Physiol. pmid:3876033
MacArthur CA et al. Chemical carcinogens induce cadmium resistance and activate metallothionein genes in cadmium sensitive S49 mouse cells. 1985 Carcinogenesis pmid:3874005
Plagemann PG et al. Adenine nucleotide metabolism and nucleoside transport in human erythrocytes under ATP depletion conditions. 1985 Biochim. Biophys. Acta pmid:3873962
Kindås-Mügge I and Sauermann G Transport of beta-globin mRNA from nuclei of murine Friend erythroleukemia cells. Reversible inhibition of transport by the oxidizing sulfhydryl reagent o-iodosobenzoate. 1985 Eur. J. Biochem. pmid:3856518
Waqar MA et al. Phosphate uptake by primary renal proximal tubule cell cultures grown in hormonally defined medium. 1985 J. Cell. Physiol. pmid:3850091
Zawalich WS et al. Metabolism and insulin-releasing capabilities of glucosamine and N-acetylglucosamine in isolated rat islets. 1979 Biochem. J. pmid:384996
Smith S et al. Mammalian fatty acid synthetase is a structurally and functionally symmetrical dimer. 1985 Eur. J. Biochem. pmid:3840436
Yamato S et al. Spectrophotometric determination of inorganic phosphate in the presence of thiol compounds. 1986 Anal. Biochem. pmid:3812971
Said HM and Redha R A carrier-mediated system for transport of biotin in rat intestine in vitro. 1987 Am. J. Physiol. pmid:3812688
Song KB et al. Requirement for a sulfhydryl group for sulfhydryl oxidase activity. 1986 J. Dairy Sci. pmid:3805443
Whitney PL et al. Oxidation and chemical modification of lung beta-galactoside-specific lectin. 1986 Biochem. J. pmid:3800956
Allen DG et al. Metabolic consequences of increasing intracellular calcium and force production in perfused ferret hearts. 1986 J. Physiol. (Lond.) pmid:3795073
Braunlin EA et al. Myoglobin facilitated oxygen diffusion maintains mechanical function of mammalian cardiac muscle. 1986 Cardiovasc. Res. pmid:3791352
Brandau DT et al. The effect of interchain disulfide bond cleavage on the cold induced precipitation of cryoimmunoglobulins. 1986 Immunol. Invest. pmid:3781575
Suzuki H [Heme transport from mitochondria to apocytochrome b5 incorporated into phospholipid vesicles by cytosolic liver protein]. 1986 Hokkaido Igaku Zasshi pmid:3781470
Vander Heide RS et al. Energy dependence of contraction band formation in perfused hearts and isolated adult myocytes. 1986 Am. J. Pathol. pmid:3777140
ToleÄ­kis AI et al. [Dynamics of the accumulation of nonesterified fatty acids in the rabbit myocardium in total ischemia]. 1986 Jul-Aug Vopr. Med. Khim. pmid:3765502
Vinall PE and Simeone FA Effects of oxygen and glucose deprivation on vasoactivity in isolated bovine middle cerebral arteries. 1986 Sep-Oct Stroke pmid:3764969
Ientile R et al. Polyamine localization and biosynthesis in chemically fractionated rat retina. 1986 J. Neurochem. pmid:3760865
Gomi T et al. S-adenosylhomocysteinase from rat liver. Amino acid sequences of the peptides containing active site cysteine residues modified by treatment with 5'-p-fluorosulfonylbenzoyladenosine. 1986 J. Biol. Chem. pmid:3759971
Stan-Lotter H and Bragg PD Electrophoretic determination of sulfhydryl groups and its application to complex protein samples, in vitro protein synthesis mixtures, and cross-linked proteins. 1986 Biochem. Cell Biol. pmid:3755048
Ricci G et al. Interaction of pantetheinase with sulfhydryl reagents and disulfides. 1986 Biochim. Biophys. Acta pmid:3753883
Manda P and Kakulas BA The effect of the myotoxic agent iodoacetate on dystrophic mice 129/Re. 1986 J. Neurol. Sci. pmid:3746339
Moore MA et al. Evidence for the existence of covalent nucleotide-thymidylate synthase complexes, identification of site of attachment, and enhancement by folates. 1986 J. Biol. Chem. pmid:3745210
Lock EA et al. Transport of N-acetyl-S-pentachloro-1,3-butadienylcysteine by rat renal cortex. 1986 Arch. Toxicol. pmid:3741137
Heller SL et al. IMP response: an indicator of metabolic stress in working muscle. 1986 Jul-Aug Muscle Nerve pmid:3736584
Rioux CR et al. Anthranilate-promoted iron uptake in Rhizobium leguminosarum. 1986 Arch. Biochem. Biophys. pmid:3729414
Zawalich WS et al. On the biochemical nature of triose- and hexose-stimulated insulin secretion. 1978 Endocrinology pmid:371954
Liotti FS and Locci P Onset and growth rate of solid tumours derived from implanted ascites tumour cells pretreated with ascorbic acid. 1986 Boll Ist Sieroter Milan pmid:3718681
Suzuki R et al. [Divalent chelating agents, calcium blockers and metabolic inhibitors had different effects on the iris sphincter muscles]. 1986 Nippon Ganka Gakkai Zasshi pmid:3716941
Irie M et al. Site of alkylation of the major ribonuclease from Aspergillus saitoi with iodoacetate. 1986 J. Biochem. pmid:3711038
Sayeed MM Alterations in cellular Ca2+ regulation in the liver in endotoxic shock. 1986 Am. J. Physiol. pmid:3706573
Mitra G and Ng PK Hepatitis B virus associated DNA polymerase inactivation in factor IX concentrates. 1986 Thromb. Res. pmid:3705011
Said HM et al. Intestinal surface acid microclimate in vitro and in vivo in the rat. 1986 J. Lab. Clin. Med. pmid:3701189
Gacond JJ et al. Analysis of folding intermediates from the main toxin of Naja naja samarensis containing two blocked cysteines. 1986 FEBS Lett. pmid:3699158
Barry AC et al. Protective effect of glucose on the anoxic myocardium of old and young mice. 1987 Mech. Ageing Dev. pmid:3695592
Von Behren LA and Pesanti EL Uptake and degradation of Pneumocystis carinii by macrophages in vitro. 1978 Am. Rev. Respir. Dis. pmid:369410
Brockbank WJ and Lynn KR Purification and preliminary characterization of two asclepains from the latex of Asclepias syriaca L. (milkweed). 1979 Biochim. Biophys. Acta pmid:36921
Calviello G et al. Further observations on the effect of calcium ionophores on ascites tumor cells. 1987 Arch. Biochem. Biophys. pmid:3688885
Murphy E et al. Biochemical and structural changes in cultured heart cells induced by metabolic inhibition. 1987 Am. J. Physiol. pmid:3688218
Said HM et al. Studies on the intestinal surface acid microclimate: developmental aspects. 1987 Pediatr. Res. pmid:3684377
Fujioka M et al. Function and reactivity of sulfhydryl groups of rat liver glycine methyltransferase. 1987 Biochemistry pmid:3676278
De Bisschop HC et al. Stereoselective hydrolysis of soman in human plasma and serum. 1987 Biochem. Pharmacol. pmid:3675614
Canfield LM Vitamin K-dependent oxygenase/carboxylase; differential inactivation by sulfhydryl reagents. 1987 Biochem. Biophys. Res. Commun. pmid:3675572
Brodie AE and Reed DJ Reversible oxidation of glyceraldehyde 3-phosphate dehydrogenase thiols in human lung carcinoma cells by hydrogen peroxide. 1987 Biochem. Biophys. Res. Commun. pmid:3675570
Al-Saleh S et al. On the disulphide bonds of rhodopsins. 1987 Biochem. J. pmid:3675552
Newsome DA and Rothman RJ Zinc uptake in vitro by human retinal pigment epithelium. 1987 Invest. Ophthalmol. Vis. Sci. pmid:3667151
Oteiza PI et al. Cyst(e)ine residues of bovine white-matter proteolipid proteins. Role of disulphides in proteolipid conformation. 1987 Biochem. J. pmid:3663175
Yovich JV et al. Effects of polysulfated glycosaminoglycan on chemical and physical defects in equine articular cartilage. 1987 Am. J. Vet. Res. pmid:3662210
Lussier LM et al. Human alveolar macrophages: antigen-independent binding of lymphocytes. 1978 J Appl Physiol Respir Environ Exerc Physiol pmid:365839
Bartha E et al. Molecular form of human lymphocyte membrane-bound acetylcholinesterase. 1987 Life Sci. pmid:3657387
Altschuld RA et al. Degradation and resynthesis of adenine nucleotides in adult rat heart myocytes. 1987 J. Biol. Chem. pmid:3654628
Turner E et al. Ovothiols, a family of redox-active mercaptohistidine compounds from marine invertebrate eggs. 1987 Biochemistry pmid:3651433
Kalbhen DA Chemical model of osteoarthritis--a pharmacological evaluation. 1987 J. Rheumatol. pmid:3625668
Coetzee WA and Opie LH Effects of components of ischemia and metabolic inhibition on delayed afterdepolarizations in guinea pig papillary muscle. 1987 Circ. Res. pmid:3621482
Pirolo JS and Allen DG Assessment of techniques for preventing glycolysis in cardiac muscle. 1986 Cardiovasc. Res. pmid:3621285
Smith RE and MacQuarrie R The role of cysteine residues in the catalytic activity of glycerol-3-phosphate dehydrogenase. 1979 Biochim. Biophys. Acta pmid:36150
Campbell CJ and Park MV The role of the available sulphydryl group in liver butyryl-coenzyme A synthetase. 1987 Int. J. Biochem. pmid:3609444
Gan ZR and Wells WW Preparation of homogeneous pig liver thioltransferase by a thiol:disulfide mediated pI shift. 1987 Anal. Biochem. pmid:3605592
Kaye NM and Jollès P Characterization of the amino acids of bovine fibrinogen involved in the fibrinogen-thrombin interaction of the blood clotting process. Comparison with the milk clotting process. 1978 Mol. Cell. Biochem. pmid:360048
Lee SL and Fanburg BL Glycolytic activity and enhancement of serotonin uptake by endothelial cells exposed to hypoxia/anoxia. 1987 Circ. Res. pmid:3594745
Haworth RA et al. Inhibition of calcium influx in isolated adult rat heart cells by ATP depletion. 1987 Circ. Res. pmid:3594742
Kempski O et al. Control of glial cell volume in anoxia. In vitro studies on ischemic cell swelling. 1987 May-Jun Stroke pmid:3590256
Johnson EM et al. Altered nucleosomes of active nucleolar chromatin contain accessible histone H3 in its hyperacetylated forms. 1987 J. Biol. Chem. pmid:3584101
Sugiyama T et al. A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia. 1987 Blood pmid:3580576
Gorman JJ Fluorescent labeling of cysteinyl residues to facilitate electrophoretic isolation of proteins suitable for amino-terminal sequence analysis. 1987 Anal. Biochem. pmid:3578767
Lövgren B and Hellstrand P Functional role of aerobic glycolysis in rat portal vein. 1987 Acta Physiol. Scand. pmid:3577809
Gan ZR and Wells WW Identification and reactivity of the catalytic site of pig liver thioltransferase. 1987 J. Biol. Chem. pmid:3571279
Jarroll EL et al. Giardia lamblia: uptake of pyrimidine nucleosides. 1987 Exp. Parasitol. pmid:3569473
Hermsdorf CL Tripeptide-specific aminopeptidase from Escherichia coli AJ005. 1978 Biochemistry pmid:356879
Aurich H et al. [Kinetics of membrane-bound aldehyde dehydrogenase from Acinetobacter calcoaceticus]. 1987 Biol. Chem. Hoppe-Seyler pmid:3566912
Yasuhara T and Ohashi A New chelator-sensitive proteases in matrix of yeast mitochondria. 1987 Biochem. Biophys. Res. Commun. pmid:3555485
Wada A Analysis of Escherichia coli ribosomal proteins by an improved two dimensional gel electrophoresis. II. Characterization of four new proteins. 1986 J. Biochem. pmid:3553169
Takeda M et al. Isolation, and catalytic and immunochemical properties of cathepsin D-like acid proteinase from rat erythrocytes. 1986 J. Biochem. pmid:3546279
Shieh JH et al. Purification and characterization of human colony-stimulating factor 1 from human pancreatic carcinoma (MIA PaCa-2) cells. 1987 Arch. Biochem. Biophys. pmid:3545083
Wakabayashi S et al. [The effect of glucose concentrations on the functional maturation of monolayer-cultured B cells of neonatal rat pancreases]. 1986 Nihon Naibunpi Gakkai Zasshi pmid:3542593
Reizer J and Saier MH Mechanism and regulation of phosphate transport in Streptococcus pyogenes. 1987 J. Bacteriol. pmid:3539921
Pacchiarini L et al. Role of tumor proteinases in tumor cell-induced platelet aggregation. 1986 Invasion Metastasis pmid:3536793