Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Wang XD et al. | Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate. | 2012 | PLoS ONE | pmid:22984604 |
Lee JH et al. | Alteration patterns of trabecular bone microarchitectural characteristics induced by osteoarthritis over time. | 2012 | Clin Interv Aging | pmid:22956865 |
Xie L et al. | Quantitative imaging of cartilage and bone morphology, reactive oxygen species, and vascularization in a rodent model of osteoarthritis. | 2012 | Arthritis Rheum. | pmid:22231023 |
Izumi M et al. | RBCS1A and RBCS3B, two major members within the Arabidopsis RBCS multigene family, function to yield sufficient Rubisco content for leaf photosynthetic capacity. | 2012 | J. Exp. Bot. | pmid:22223809 |
Fiaschi T et al. | Redox Regulation of Nonmuscle Myosin Heavy Chain during Integrin Engagement. | 2012 | J Signal Transduct | pmid:22220276 |
Vincent A et al. | parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress. | 2012 | Hum. Mol. Genet. | pmid:22215442 |
North SJ et al. | Glycomic analysis of human mast cells, eosinophils and basophils. | 2012 | Glycobiology | pmid:21725073 |
Ferreira-Gomes J et al. | Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat. | 2012 | Mol Pain | pmid:22769424 |
Noel JM et al. | Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage. | 2012 | Exp. Eye Res. | pmid:22251455 |
Hardes K et al. | Design, synthesis, and characterization of chromogenic substrates of coagulation factor XIIIa. | 2012 | Anal. Biochem. | pmid:22683584 |
Rao Y et al. | Mapping of sulfur metabolic pathway by LC Orbitrap mass spectrometry. | 2012 | Anal. Chim. Acta | pmid:22405311 |
Wei X et al. | Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells. | 2013 | Environ. Sci. Technol. | pmid:23641915 |
Nan Y et al. | Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat. | 2013 | Sci China Life Sci | pmid:23657794 |
More AS et al. | Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. | 2013 | Pharmacol. Biochem. Behav. | pmid:23287799 |
La Porta C et al. | Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate. | 2013 | Pain | pmid:23199705 |
Song M et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch. Toxicol. | pmid:23397585 |
Moon SJ et al. | Augmented chondroprotective effect of coadministration of celecoxib and rebamipide in the monosodium iodoacetate rat model of osteoarthritis. | 2013 | Arch. Pharm. Res. | pmid:23338062 |
Ogbonna AC et al. | Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice. | 2013 | Eur J Pain | pmid:23169679 |
Ye T et al. | Formation of iodinated disinfection by-products during oxidation of iodide-containing waters with chlorine dioxide. | 2013 | Water Res. | pmid:23561492 |
Thote T et al. | Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration. | 2013 | Osteoarthr. Cartil. | pmid:23747340 |