Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Rigor Mortis D012298 1 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteophyte D054850 2 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
Muscle Cramp D009120 3 associated lipids
Osteoarthritis D010003 4 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Retinitis D012173 4 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Thrombophilia D019851 6 associated lipids
Blindness D001766 6 associated lipids
Rickets D012279 6 associated lipids
Theileriasis D013801 7 associated lipids
Arthralgia D018771 8 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Byssinosis D002095 11 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Hypocalcemia D006996 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Thrombocytopenia D013921 15 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vascular Diseases D014652 16 associated lipids
Lymphoma D008223 18 associated lipids
Brain Edema D001929 20 associated lipids
Wounds and Injuries D014947 20 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Stroke D020521 32 associated lipids
Burns D002056 34 associated lipids
Epilepsy D004827 35 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Starvation D013217 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nerve Degeneration D009410 53 associated lipids
Pain D010146 64 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Brain Ischemia D002545 89 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Ogbonna AC et al. Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. 2015 Age (Dordr) pmid:25971876
Baker MS et al. Oxidation of articular cartilage glyceraldehyde-3-phosphate dehydrogenase (G3PDH) occurs in vivo during carrageenin-induced arthritis. 1991 Agents Actions pmid:1862748
Cunningham FM et al. Aggregation of polymorphonuclear leucocytes (PMNs) by leukotriene B4: effects of cyclooxygenase products and metabolic inhibitors. 1981 Agents Actions pmid:6280463
Lassiter C et al. HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction. 2009 AIDS Res Ther pmid:19193217
Otis JS et al. Effect of HIV-1-related protein expression on cardiac and skeletal muscles from transgenic rats. 2008 AIDS Res Ther pmid:18439274
Bühler R et al. Human liver alcohol dehydrogenase: the unique properties of the "atypical" isoenzyme beta 2 beta 2-Bern can be explained by a single base mutation. 1985 Jan-Feb Alcohol pmid:3893464
Burmeister J and Blank I [Migration and adhesiveness of human and rabbit blood leukocytes under the influence of metabolic blocking agents and hirudin]. 1983 Allerg Immunol (Leipz) pmid:6224414
Williams JA and Thonar EJ Early osteophyte formation after chemically induced articular cartilage injury. 1989 Jan-Feb Am J Sports Med pmid:2929840
Said HM et al. Intestinal uptake of retinol: enhancement by bovine milk beta-lactoglobulin. 1989 Am. J. Clin. Nutr. pmid:2929489
Gyure WL A rapid screening method for blood glucose estimation. 1977 Am. J. Clin. Pathol. pmid:900068
Yust I et al. Simultaneous detection of two mechanisms of immune destruction of penicillin-treated human red blood cells. 1982 Am. J. Hematol. pmid:7137166
Milton DK and Chawla RK Cotton dust contains proteolytic and elastolytic enzymes not inhibited by alpha-1-proteinase inhibitor. 1986 Am. J. Ind. Med. pmid:3515917
Hoskins IA et al. Use of esterase inhibitors and zone electrophoresis to define bacterial esterases in amniotic fluid. 1992 Am. J. Obstet. Gynecol. pmid:1471669
Sbarra AJ et al. Phagocytosis and onset of human labor. 1983 Am. J. Obstet. Gynecol. pmid:6869432
Armstrong SC and Ganote CE Effects of the phospholipase inhibitor mepacrine on injury in ischemic and metabolically inhibited adult isolated myocytes. 1991 Am. J. Pathol. pmid:2000934
Laiho KU et al. Observations on cell volume, ultrastructure, mitochondrial conformation and vital-dye uptake in Ehrlich ascites tumor cells. Effects of inhibiting energy production and function of the plasma membrane. 1971 Am. J. Pathol. pmid:5096366
Hawkins HK et al. Lysosome and phagosome stability in lethal cell injury. Morphologic tracer studies in cell injury due to inhibition of energy metabolism, immune cytolysis and photosensitization. 1972 Am. J. Pathol. pmid:4340333
Vander Heide RS et al. Energy dependence of contraction band formation in perfused hearts and isolated adult myocytes. 1986 Am. J. Pathol. pmid:3777140
van der Kraan PM et al. Development of osteoarthritic lesions in mice by "metabolic" and "mechanical" alterations in the knee joints. 1989 Am. J. Pathol. pmid:2556924
Ganote CE and Vander Heide RS Irreversible injury of isolated adult rat myocytes. Osmotic fragility during metabolic inhibition. 1988 Am. J. Pathol. pmid:3400772
Ruff RL and Weissman J Iodoacetate-induced contracture in rat skeletal muscle: possible role of ADP. 1991 Am. J. Physiol. pmid:1951670
Barry WH et al. Effects of graded hypoxia on contraction of cultured chick embryo ventricular cells. 1980 Am. J. Physiol. pmid:7435640
Ito Y et al. Oxidative stress increases glyceraldehyde-3-phosphate dehydrogenase mRNA levels in isolated rabbit aorta. 1996 Am. J. Physiol. pmid:8769737
Plishker GA et al. Involvement of a cytoplasmic protein in calcium-dependent potassium efflux in red blood cells. 1986 Am. J. Physiol. pmid:3532815
Wu Y et al. Alterations in reactive oxygen, pH, and calcium in astrocytoma cells during lethal injury. 1996 Am. J. Physiol. pmid:8772436
Matsumoto Y et al. Creatine kinase kinetics in diabetic cardiomyopathy. 1995 Am. J. Physiol. pmid:7611380
Fiddian-Green RG and Silen W Mechanisms of disposal of acid and alkali in rabbit duodenum. 1975 Am. J. Physiol. pmid:2019
Koss KL et al. Mg2+ buffering in cultured chick ventricular myocytes: quantitation and modulation by Ca2+. 1993 Am. J. Physiol. pmid:8498485
Satoh H and Vassalle M Role of calcium in caffeine-norepinephrine interactions in cardiac Purkinje fibers. 1989 Am. J. Physiol. pmid:2750939
Gores GJ et al. Swelling, reductive stress, and cell death during chemical hypoxia in hepatocytes. 1989 Am. J. Physiol. pmid:2764095
Chih CP et al. Energy metabolism, ion homeostasis, and evoked potentials in anoxic turtle brain. 1989 Am. J. Physiol. pmid:2802002
Conrad CH et al. Outward current and repolarization in hypoxic rat myocardium. 1983 Am. J. Physiol. pmid:6829776
Griendling KK et al. Pregnancy-induced changes in sheep uterine and carotid arteries. 1985 Am. J. Physiol. pmid:2581458
Ramp WK and Demaree DN Inhibition of net calcium efflux from bone by ethanol in vitro. 1984 Am. J. Physiol. pmid:6696057
Wendt IR and Chapman JB Fluorometric studies of recovery metabolism of rat fast- and slow-twitch muscles. 1976 Am. J. Physiol. pmid:937554
Wendt IR and Gibbs CL Recovery heat production of mammalian fast- and slow-twitch muscles. 1976 Am. J. Physiol. pmid:937562
Alvarado RH et al. Chloride transport across isolated skin of Rana pipiens. 1975 Am. J. Physiol. pmid:1082245
Bagnasco S et al. Lactate production in isolated segments of the rat nephron. 1985 Am. J. Physiol. pmid:3985159
Plishker GA Iodoacetic acid inhibition of calcium-dependent potassium efflux in red blood cells. 1985 Am. J. Physiol. pmid:3993768
Beauwens R et al. Polycations reduce vasopressin-induced water flow by endocytic removal of water channels. 1986 Am. J. Physiol. pmid:3010730
Post JA et al. pHe, [Ca2+]e, and cell death during metabolic inhibition: role of phospholipase A2 and sarcolemmal phospholipids. 1998 Am. J. Physiol. pmid:9458847
Herchuelz A and Malaisse WJ Regulation of calcium fluxes in pancreatic islets: two calcium movements' dissociated response to glucose. 1980 Am. J. Physiol. pmid:6767412
Sick TJ et al. Brain potassium ion homeostasis, anoxia, and metabolic inhibition in turtles and rats. 1982 Am. J. Physiol. pmid:6287869
SANDOW A and KARCZMAR AG Effect of iodoacetate on changes in muscular latency induced by activity. 1950 Am. J. Physiol. pmid:14789991
Shryock JC et al. Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. 1988 Am. J. Physiol. pmid:3344813
Yokozeki H et al. Partial purification and characterization of cysteine proteinases in eccrine sweat. 1987 Am. J. Physiol. pmid:3109264
Chamberlin ME and Mandel LJ Na+-K+-ATPase activity in medullary thick ascending limb during short-term anoxia. 1987 Am. J. Physiol. pmid:3034075
DiGregorio KA et al. Measurement of superoxide release from single pulmonary alveolar macrophages. 1987 Am. J. Physiol. pmid:3035935
Plishker GA Effects of cadmium and zinc on calcium uptake in human red blood cells. 1984 Am. J. Physiol. pmid:6089571
Steinberg H et al. Depression of pulmonary 5-hydroxytryptamine uptake by metabolic inhibitors. 1975 Am. J. Physiol. pmid:1130533
Strewler GJ Release of cAMP from a renal epithelial cell line. 1984 Am. J. Physiol. pmid:6322592
Bowman RH et al. Furosemide, ethacrynic acid, and iodoacetate on function and metabolism in perfused rat kidney. 1973 Am. J. Physiol. pmid:4686497
Stokes JB et al. Purification of rat papillary collecting duct cells: functional and metabolic assessment. 1987 Am. J. Physiol. pmid:3303974
Murphy E et al. Biochemical and structural changes in cultured heart cells induced by metabolic inhibition. 1987 Am. J. Physiol. pmid:3688218
Xia Y et al. Oxidative and glycolytic pathways in rat (newborn and adult) and turtle brain: role during anoxia. 1992 Am. J. Physiol. pmid:1314516
Norris SH and Hersey SJ Stimulation of pepsinogen secretion in permeable isolated gastric glands. 1985 Am. J. Physiol. pmid:3876033
Sumpio BE and Maack T Kinetics, competition, and selectivity of tubular absorption of proteins. 1982 Am. J. Physiol. pmid:7124951
Johnson V and Maack T Renal extraction, filtration, absorption, and catabolism of growth hormone. 1977 Am. J. Physiol. pmid:910912
Hartmund T and Gesser H Cardiac force and high-energy phosphates under metabolic inhibition in four ectothermic vertebrates. 1996 Am. J. Physiol. pmid:8897986
Said HM and Redha R A carrier-mediated system for transport of biotin in rat intestine in vitro. 1987 Am. J. Physiol. pmid:3812688
Apstein CS et al. Acute cardiac ischemia and reperfusion: contractility, relaxation, and glycolysis. 1978 Am. J. Physiol. pmid:736151
Sahlin K et al. Effects of lactic acid accumulation and ATP decrease on muscle tension and relaxation. 1981 Am. J. Physiol. pmid:7212053
Kone BC et al. Cellular pathways of potassium transport in renal inner medullary collecting duct. 1989 Am. J. Physiol. pmid:2539729
Sayeed MM Alterations in cellular Ca2+ regulation in the liver in endotoxic shock. 1986 Am. J. Physiol. pmid:3706573
Rodríguez-Estrada C Reduced nicotinamide adenine dinucleotide and depolarization in neurons. 1975 Am. J. Physiol. pmid:165729
Fang HK et al. Cardiac contractile function during coronary stenosis in dogs: association of adenosine in glycolytic dependence. 1997 Am. J. Physiol. pmid:9176286
Koss KL and Grubbs RD Elevated extracellular Mg2+ increases Mg2+ buffering through a Ca-dependent mechanism in cardiomyocytes. 1994 Am. J. Physiol. pmid:8074196
Gramolini A and Renaud JM Blocking ATP-sensitive K+ channel during metabolic inhibition impairs muscle contractility. 1997 Am. J. Physiol. pmid:9227423
Xie LH et al. Development of inwardly rectifying K+ channel family in rat ventricular myocytes. 1997 Am. J. Physiol. pmid:9139958
Pautler EL et al. Modification of leucine transport across bovine pigment epithelium by metabolic stress. 1989 Am. J. Physiol. pmid:2596588
Dobrin P and Canfield T Identification of smooth muscle series elastic component in intact carotid artery. 1977 Am. J. Physiol. pmid:190898
Lorenz JN and Paul RJ Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. 1997 Am. J. Physiol. pmid:9124463
Gores GJ et al. Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes. 1988 Am. J. Physiol. pmid:3421314
Hurwitz A Drug uptake into everted intestinal sacs. II. Inhibition of secretion by hypertonicity. 1979 Am. J. Physiol. pmid:35006
Dizon J et al. Metabolic inhibition in the perfused rat heart: evidence for glycolytic requirement for normal sodium homeostasis. 1998 Am. J. Physiol. pmid:9575910
Schwarzbaum PJ et al. Functional role of ecto-ATPase activity in goldfish hepatocytes. 1998 Am. J. Physiol. pmid:9575966
Selvaggio AM et al. Mechanisms of H+ secretion by inner medullary collecting duct cells. 1988 Am. J. Physiol. pmid:3348416
Hansen SP and Gesser H Extracellular Ca2+, force, and energy state in cardiac tissue of rainbow trout. 1987 Am. J. Physiol. pmid:3425763
Nakamura K et al. Glycolysis is necessary to preserve myocardial Ca2+ homeostasis during beta-adrenergic stimulation. 1993 Am. J. Physiol. pmid:8384419
Connett RJ and Hays ET Energy coupling to sodium transport in frog skeletal muscle. 1978 Am. J. Physiol. pmid:307914
Ahearn GA Intestinal electrophysiology and transmural ion transport in freshwater prawns. 1980 Am. J. Physiol. pmid:7395980
Greenwood SL et al. Transtrophoblast and microvillus membrane potential difference in mature intermediate human placental villi. 1993 Am. J. Physiol. pmid:8368275
Miyazaki Y et al. Selective turnover of sarcolemmal phospholipids with lethal cardiac myocyte injury. 1990 Am. J. Physiol. pmid:2382705
Okamoto K et al. ATP from glycolysis is required for normal sodium homeostasis in resting fast-twitch rodent skeletal muscle. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11500303
Harrison GJ et al. Glycolytic buffering affects cardiac bioenergetic signaling and contractile reserve similar to creatine kinase. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12714331
Zhou L et al. Impact of anaerobic glycolysis and oxidative substrate selection on contractile function and mechanical efficiency during moderate severity ischemia. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18660443
Raddatz E et al. Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21193588
Chen F et al. Effects of metabolic inhibition on conduction, Ca transients, and arrhythmia vulnerability in embryonic mouse hearts. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17660398
Singla DK et al. TGF-β2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21297031
Merker MP et al. Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells. 2002 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11741813
Galli GL et al. Ca2+ cycling in cardiomyocytes from a high-performance reptile, the varanid lizard (Varanus exanthematicus). 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19812356
Pilarski JQ et al. Effects of aerobic and anaerobic metabolic inhibitors on avian intrapulmonary chemoreceptors. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19297545
Cheng AM et al. Energy dependence of restitution in the gastric mucosa. 2001 Am. J. Physiol., Cell Physiol. pmid:11443042
Yanagawa N et al. Riboflavin transport by isolated perfused rabbit renal proximal tubules. 2000 Am. J. Physiol., Cell Physiol. pmid:11078692
Aromolaran AS et al. Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. 2007 Am. J. Physiol., Cell Physiol. pmid:17344311
Gustafson SB et al. Evaluation of intra-articularly administered sodium monoiodoacetate-induced chemical injury to articular cartilage of horses. 1992 Am. J. Vet. Res. pmid:1497191
Yovich JV et al. Effects of polysulfated glycosaminoglycan on chemical and physical defects in equine articular cartilage. 1987 Am. J. Vet. Res. pmid:3662210
Roe SC et al. Biomechanical properties of canine cortical bone allografts: effects of preparation and storage. 1988 Am. J. Vet. Res. pmid:3041883
Nakai T et al. Characterization of the hemolysin produced by haemophilus pleuropneumoniae. 1983 Am. J. Vet. Res. pmid:6830024
Von Behren LA and Pesanti EL Uptake and degradation of Pneumocystis carinii by macrophages in vitro. 1978 Am. Rev. Respir. Dis. pmid:369410