Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Ralat LA and Colman RF | Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. | 2006 | Biochemistry | pmid:17029404 |
Aiedeh KM et al. | Effect of ionic crosslinking on the drug release properties of chitosan diacetate matrices. | 2007 | J Pharm Sci | pmid:17031867 |
Keough DT et al. | Localization of the 5-phospho-alpha-D-ribosyl-1-pyrophosphate binding site of human hypoxanthine-guanine phosphoribosyltransferase. | 1991 | Biochim. Biophys. Acta | pmid:1705826 |
Rogel A et al. | The neuroprotective adenosine-activated signal transduction pathway involves activation of phospholipase C. | 2006 | Nucleosides Nucleotides Nucleic Acids | pmid:17065107 |
Duewelhenke N et al. | Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. | 2007 | Antimicrob. Agents Chemother. | pmid:17088489 |
Laiho KU and Trump BF | Mitochondrial changes, ion and water shifts in the cellular injury of ehrlich ascites tumor cells. | 1975 | Beitr Pathol | pmid:170904 |
Gover TD et al. | Calcium regulation in individual peripheral sensory nerve terminals of the rat. | 2007 | J. Physiol. (Lond.) | pmid:17095566 |
MejÃa-Toiber J et al. | D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo. | 2006 | Neurochem. Res. | pmid:17115265 |
Liang L et al. | Purification and characterization of trehalose-6-phosphate synthase from Saccharomycopsis fibuligera A11. | 2006 | Indian J. Biochem. Biophys. | pmid:17133735 |
Munger J et al. | Dynamics of the cellular metabolome during human cytomegalovirus infection. | 2006 | PLoS Pathog. | pmid:17173481 |
Hashimoto S et al. | Dependence of platelet adenyl cyclase system on oxidative phosphorylation. | 1975 | Thromb Diath Haemorrh | pmid:171798 |
pmid:17189169 | ||||
Morgan A and Maliga P | Rapid chloroplast segregation and recombination of mitochondrial DNA in Brassica cybrids. | 1987 | Mol. Gen. Genet. | pmid:17191340 |
pmid:17206661 | ||||
pmid:17218122 | ||||
Kito Y and Suzuki H | Effects of temperature on pacemaker potentials in the mouse small intestine. | 2007 | Pflugers Arch. | pmid:17235578 |
Menczel L et al. | Effect of radiation dosage on efficiency of chloroplast transfer by protoplast fusion in Nicotiana. | 1982 | Genetics | pmid:17246066 |
Raffin CN et al. | Glycolysis, oxidative metabolism, and brain potassium ion clearance. | 1992 | J. Cereb. Blood Flow Metab. | pmid:1727141 |
Ivanavicius SP et al. | Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF-3 and pharmacological characterisation. | 2007 | Pain | pmid:17276007 |
Appleton CT et al. | Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis. | 2007 | Arthritis Res. Ther. | pmid:17284317 |
Beyreuther B et al. | Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain. | 2007 | Arthritis Res. Ther. | pmid:17284318 |
pmid:17299207 | ||||
pmid:17301007 | ||||
Gatson JW and Singh M | Activation of a membrane-associated androgen receptor promotes cell death in primary cortical astrocytes. | 2007 | Endocrinology | pmid:17303658 |
Pot DA and Dixon JE | Active site labeling of a receptor-like protein tyrosine phosphatase. | 1992 | J. Biol. Chem. | pmid:1730581 |
Zherebtsov NA and Krayushkina EA | [Some properties of proteases of the mould Mucor pusillus-917]. | 1975 May-Jun | Prikl. Biokhim. Mikrobiol. | pmid:1731 |
Buttle DJ et al. | Inhibition of interleukin 1-stimulated cartilage proteoglycan degradation by a lipophilic inactivator of cysteine endopeptidases. | 1992 | Biochem. J. | pmid:1731753 |
Aromolaran AS et al. | Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. | 2007 | Am. J. Physiol., Cell Physiol. | pmid:17344311 |
pmid:17345116 | ||||
Silva CM and Cidlowski JA | The effect of oxidation/reduction on the charge heterogeneity of the human glucocorticoid receptor. | 1992 | J. Steroid Biochem. Mol. Biol. | pmid:1734932 |
Zhang ZY et al. | Covalent modification and active site-directed inactivation of a low molecular weight phosphotyrosyl protein phosphatase. | 1992 | Biochemistry | pmid:1737025 |
Notsu T et al. | Blockade of the ATP-sensitive K+ channel by 5-hydroxydecanoate in guinea pig ventricular myocytes. | 1992 | J. Pharmacol. Exp. Ther. | pmid:1738118 |
Marinkovic DV and Marinkovic JN | Purification of two hexosaminidases from human kidney. | 1977 | Biochem. J. | pmid:17390 |
Neugebauer V et al. | Techniques for assessing knee joint pain in arthritis. | 2007 | Mol Pain | pmid:17391515 |
pmid:17447005 | ||||
Lew VL et al. | Effects of age-dependent membrane transport changes on the homeostasis of senescent human red blood cells. | 2007 | Blood | pmid:17456724 |
Nakai T et al. | Proteolysis of canine apolipoprotein by acid proteases in canine liver lysosomes. | 1976 | Biochim. Biophys. Acta | pmid:174745 |
Barve RA et al. | Transcriptional profiling and pathway analysis of monosodium iodoacetate-induced experimental osteoarthritis in rats: relevance to human disease. | 2007 | Osteoarthr. Cartil. | pmid:17500014 |
pmid:17545192 | ||||
Dray A and Read SJ | Arthritis and pain. Future targets to control osteoarthritis pain. | 2007 | Arthritis Res. Ther. | pmid:17561993 |
Perks AM et al. | Lung liquid production by in vitro lungs from fetal guinea pigs: studies with metabolic inhibitors. | 1991 | Can. J. Physiol. Pharmacol. | pmid:1756423 |
pmid:17571896 | ||||
pmid:17583780 | ||||
pmid:17609869 | ||||
Lowenhaupt RW et al. | Factors which influence blood platelet migration. | 1977 | J. Lab. Clin. Med. | pmid:17642 |
Chen F et al. | Effects of metabolic inhibition on conduction, Ca transients, and arrhythmia vulnerability in embryonic mouse hearts. | 2007 | Am. J. Physiol. Heart Circ. Physiol. | pmid:17660398 |
pmid:17687604 | ||||
Froelich JM and Reid GE | Mechanisms for the proton mobility-dependent gas-phase fragmentation reactions of S-alkyl cysteine sulfoxide-containing peptide ions. | 2007 | J. Am. Soc. Mass Spectrom. | pmid:17689096 |
pmid:17691843 | ||||
Serban MA and Prestwich GD | Synthesis of hyaluronan haloacetates and biology of novel cross-linker-free synthetic extracellular matrix hydrogels. | 2007 | Biomacromolecules | pmid:17696398 |