Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Lee FS et al. | Primary structure of human placental ribonuclease inhibitor. | 1988 | Biochemistry | pmid:3219362 |
Nieminen AL et al. | Calcium dependence of bleb formation and cell death in hepatocytes. | 1988 | Cell Calcium | pmid:3224370 |
Feeback DL et al. | Metabolic myopathy produced by dinitrofluorobenzene inhibition of creatine phosphokinase. | 1988 | J. Neurol. Sci. | pmid:3225621 |
Chhatwal GS and Gaitonde BB | Purification of a nontoxic phospholipase A2 from the venom of Indian krait (Bungarus caeruleus). | 1978 | Jpn. J. Med. Sci. Biol. | pmid:32414 |
Altland K et al. | Isoelectric focusing of basic proteins: the problem of oxidation of cysteines. | 1988 | Electrophoresis | pmid:3243245 |
Skul'skiÄ IA and Pivovarova NB | [Effect of inhibitors of energy metabolism on potassium accumulation in the neurons of the mollusk Planorbarius corneus]. | 1988 Nov-Dec | Zh. Evol. Biokhim. Fiziol. | pmid:3245356 |
Kempski O et al. | Molecular mechanisms of glial swelling in vitro. | 1988 Jul-Dec | Neurochem Pathol | pmid:3247066 |
Thomas JA and Park EM | Oxy radical-initiated protein S-thiolation and enzymic dethiolation. | 1988 | Basic Life Sci. | pmid:3250494 |
Bountra C et al. | Mechanism of rate-dependent pH changes in the sheep cardiac Purkinje fibre. | 1988 | J. Physiol. (Lond.) | pmid:3254421 |
Zoref-Shani E et al. | Pathways of adenine nucleotide catabolism in primary rat cardiomyocyte cultures. | 1988 | J. Mol. Cell. Cardiol. | pmid:3259263 |
Sterchi EE et al. | N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase: a metalloendopeptidase of the human intestinal microvillus membrane which degrades biologically active peptides. | 1988 | Arch. Biochem. Biophys. | pmid:3261961 |
Turkelson CM | Effects of ATP synthesis inhibitors, temperature, 8-bromo c-AMP, and calcium omission on release of corticotropin releasing factor from superfused rat hypothalami. | 1988 | Life Sci. | pmid:3262804 |
Okorokov LA et al. | Energy-dependent transport of manganese into yeast cells and distribution of accumulated ions. | 1977 | Eur. J. Biochem. | pmid:328273 |
Mittenbühler K and Holzer H | Purification and characterization of acid trehalase from the yeast suc2 mutant. | 1988 | J. Biol. Chem. | pmid:3286651 |
Miller DM and Harun SH | The kinetics of the active and de-energized transport of O-methyl glucose in Ustilago maydis. | 1978 | Biochim. Biophys. Acta | pmid:32904 |
Wakabayashi S et al. | [Perifusion of monolayer-cultured B cells of the infant rat: a comparative study of the effects of 2-deoxy-2-fluoroglucose and iodoacetic acid]. | 1988 | Nihon Naibunpi Gakkai Zasshi | pmid:3294052 |
Lockwood BC et al. | The use of a highly sensitive electrophoretic method to compare the proteinases of trichomonads. | 1987 | Mol. Biochem. Parasitol. | pmid:3302703 |
Stokes JB et al. | Purification of rat papillary collecting duct cells: functional and metabolic assessment. | 1987 | Am. J. Physiol. | pmid:3303974 |
Yamamoto K et al. | Affinity purification and properties of cathepsin-E-like acid proteinase from rat spleen. | 1978 | Eur. J. Biochem. | pmid:33048 |
Dunbar JC and Bradshaw RA | Amino acid sequence of guinea pig prostate kallikrein. | 1987 | Biochemistry | pmid:3307909 |
Polgár L and Csoma C | Dissociation of ionizing groups in the binding cleft inversely controls the endo- and exopeptidase activities of cathepsin B. | 1987 | J. Biol. Chem. | pmid:3312190 |
Wakabayashi S et al. | Maintenance of neonatal rat B cells in glucose-depleted medium: a perifusion study. | 1987 | J. Endocrinol. | pmid:3312465 |
Campbell-Burk SL et al. | 31P NMR saturation-transfer measurements in Saccharomyces cerevisiae: characterization of phosphate exchange reactions by iodoacetate and antimycin A inhibition. | 1987 | Biochemistry | pmid:3322400 |
Kagawa S et al. | Maintenance of pancreatic endocrine cells of the neonatal rat: Part XII--Development of the response by infant rat pancreatic monolayer-cultured B cells. | 1987 | Indian J. Biochem. Biophys. | pmid:3329630 |
Andrews PA et al. | cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells. | 1988 | Cancer Res. | pmid:3335000 |
Zaager S and Burke M | Subunit interactions of skeletal muscle myosin and myosin subfragment 1. Evidence for heavy chain-alkali light chain association-dissociation equilibrium. | 1988 | J. Biol. Chem. | pmid:3335556 |
Maublant JC et al. | Hexakis (2-methoxy isobutylisonitrile) technetium-99m and thallium-201 chloride: uptake and release in cultured myocardial cells. | 1988 | J. Nucl. Med. | pmid:3335927 |
Okitani A et al. | Purification and some properties of cathepsin B from rabbit skeletal muscle. | 1988 | Eur. J. Biochem. | pmid:3338470 |
Shryock JC et al. | Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. | 1988 | Am. J. Physiol. | pmid:3344813 |
Corbo RM et al. | Effect of some thiol reagents on erythrocyte adenosine deaminase (ADA) activity. | 1988 | Enzyme | pmid:3345734 |
Selvaggio AM et al. | Mechanisms of H+ secretion by inner medullary collecting duct cells. | 1988 | Am. J. Physiol. | pmid:3348416 |
Seymour CB and Mothersill C | The effect of glycolysis inhibitors on the radiation response of CHO-K1 cells. | 1988 | Radiat Environ Biophys | pmid:3353494 |
Hirose M et al. | Analyses of intramolecular disulfide bonds in proteins by polyacrylamide gel electrophoresis following two-step alkylation. | 1988 | Anal. Biochem. | pmid:3364712 |
Plank DW and Howard JB | Identification of the reactive sulfhydryl and sequences of cysteinyl-tryptic peptides from beef heart aconitase. | 1988 | J. Biol. Chem. | pmid:3372519 |
Schurr A et al. | Lactate-supported synaptic function in the rat hippocampal slice preparation. | 1988 | Science | pmid:3375817 |
Maiorino M et al. | Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51). | 1988 | Biochem. Pharmacol. | pmid:3377822 |
Neeff J and Mecke D | In vivo and in vitro studies on the glucose dependent inactivation of yeast cytoplasmic malate dehydrogenase. | 1977 | Arch. Microbiol. | pmid:337921 |
Chersi A et al. | 14C-labeling of synthetic peptides. | 1988 | J. Immunol. Methods | pmid:3379315 |
Horn V et al. | [Experimental arthrosis caused by chemical cartilage damage]. | 1988 Jan-Feb | Z Orthop Ihre Grenzgeb | pmid:3381573 |
Bouvet OM and Grimont PA | Extracellular oxidation of D-glucose by some members of the Enterobacteriaceae. | 1988 Jan-Feb | Ann. Inst. Pasteur Microbiol. | pmid:3382545 |
Kaya T et al. | Purification and properties of alpha-mannosidase from bakers' yeast. | 1977 | J. Biochem. | pmid:338603 |
Rainard P | Adherence, spreading, and locomotion of bovine polymorphs: effect of proteins and metabolic inhibitors. | 1988 | Vet. Immunol. Immunopathol. | pmid:3388760 |
Bersinger NA et al. | Effect of protein synthesis inhibitors and metabolic blockers on the production of placental proteins by the in vitro perfused human placenta. | 1988 | Gynecol. Obstet. Invest. | pmid:3391424 |
Fishbein WN et al. | Clinical assay of the human erythrocyte lactate transporter. I. Principles, procedure, and validation. | 1988 | Biochem. Med. Metab. Biol. | pmid:3395513 |
Carlsson L | A crucial role of ongoing anaerobic glycolysis in attenuating acute ischemia-induced release of myocardial noradrenaline. | 1988 | J. Mol. Cell. Cardiol. | pmid:3398056 |
Ganote CE and Vander Heide RS | Irreversible injury of isolated adult rat myocytes. Osmotic fragility during metabolic inhibition. | 1988 | Am. J. Pathol. | pmid:3400772 |
Thomas AM et al. | The uptake of choline by Streptococcus pneumoniae. | 1978 | J. Gen. Microbiol. | pmid:34010 |
Bolin R et al. | Glycolysis is not required for fluid homeostasis in isolated rabbit lungs. | 1988 | J. Appl. Physiol. | pmid:3403435 |
Decottignies P et al. | Primary structure of the light-dependent regulatory site of corn NADP-malate dehydrogenase. | 1988 | J. Biol. Chem. | pmid:3403553 |
Mielicki W and Wierzbicki R | Factor X-activating activity from Guerin epithelioma. | 1988 | Neoplasma | pmid:3405336 |
Buttner B et al. | Chromate effects on human erythrocytes--investigations on sulphydryl groups, cross-linking of membrane proteins and electromechanical properties in the coulter-counter. | 1988 | Sci. Total Environ. | pmid:3406723 |
Yamada T and Sugi H | 31P NMR study of the regulation of glycogenolysis in iodoacetate-treated skeletal muscle. | 1988 | Adv. Exp. Med. Biol. | pmid:3407526 |
Kihlström E and Nilsson L | Endocytosis of Salmonella typhimurium 395 MS and MR10 by HeLa cells. | 1977 | Acta Pathol Microbiol Scand B | pmid:341644 |
Gores GJ et al. | Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes. | 1988 | Am. J. Physiol. | pmid:3421314 |
Hansen SP and Gesser H | Extracellular Ca2+, force, and energy state in cardiac tissue of rainbow trout. | 1987 | Am. J. Physiol. | pmid:3425763 |
Chen CC et al. | Rat intestinal trehalase. Studies of the active site. | 1987 | Biochem. J. | pmid:3426558 |
Seymour CB and Mothersill C | The effect of glycolysis inhibitors on the recovery of CHO-K1 cells from split-dose irradiation. | 1987 | Acta Oncol | pmid:3426849 |
Kingsley-Hickman PB et al. | 31P NMR studies of ATP synthesis and hydrolysis kinetics in the intact myocardium. | 1987 | Biochemistry | pmid:3427090 |
Knipping G et al. | Action of lecithin-cholesterol acyltransferase on low-density lipoproteins in native pig plasma. | 1987 | Biochemistry | pmid:3427116 |
Roullet B et al. | [Determination of serum glycosylated proteins in normoglycemic patients with cancer]. | 1987 | Bull Cancer | pmid:3435788 |
Kobayashi H et al. | Effects of arsenic on cholinergic parameters in brain in vitro. | 1987 | Neuropharmacology | pmid:3437937 |
Pantin VI et al. | [Similarity of adhesion to phagocytosis: macrophage interaction with different substrates]. | 1987 | Tsitologiia | pmid:3438934 |
Zimmerle CT et al. | Ligand-induced asymmetry between active sites of cytoplasmic malate dehydrogenase: a chemical modification study. | 1987 | Biochemistry | pmid:3442674 |
Fontan E and Truffa-Bachi P | The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. Carboxymethylation of the enzyme: threonine binding and inhibition are functionally dissociable. | 1978 | J. Biol. Chem. | pmid:344322 |
Uruno T et al. | Determination of Ca2+-release from the isolated smooth muscle cells in suspension from the guinea-pig ileum. | 1987 | Nihon Heikatsukin Gakkai Zasshi | pmid:3444154 |
Piper B et al. | The influence of various substances on the gliding motility of Mycoplasma mobile 163K. | 1987 | J. Gen. Microbiol. | pmid:3446749 |
Berni R et al. | New crystalline derivatives of bovine liver rhodanese. | 1986 | Biochem. Int. | pmid:3460592 |
Kajiya H et al. | [Effects of three different metabolic inhibitors (2,4-dinitrophenol, iodoacetic acid, 2,4-fluorodinitrobenzene) on the contractility of the geniohyoid and sartorius muscles]. | 1986 | Fukuoka Shika Daigaku Gakkai Zasshi | pmid:3464458 |
Shapiro R et al. | Isolation and characterization of a human colon carcinoma-secreted enzyme with pancreatic ribonuclease-like activity. | 1986 | Biochemistry | pmid:3467790 |
Cannella C et al. | Active site modifications quench intrinsic fluorescence of rhodanese by different mechanisms. | 1986 | Biochemistry | pmid:3467793 |
Bagnall WE et al. | The gastrointestinal absorption of paracetamol in the rat. | 1979 | J. Pharm. Pharmacol. | pmid:34689 |
Bawden JW et al. | Diffusion of fluoride through the rat enamel organ in vitro. | 1987 | J. Dent. Res. | pmid:3476606 |
Kobayashi T et al. | Effect of iodoacetic acid upon cochlear potentials. | 1987 | Acta Otolaryngol Suppl | pmid:3478950 |
Olesen SP | Rapid increase in blood-brain barrier permeability during severe hypoxia and metabolic inhibition. | 1986 | Brain Res. | pmid:3485464 |
Gilbert SH and Ford LE | The thermoelastic effect in rigor muscle of the frog. | 1986 | J. Muscle Res. Cell. Motil. | pmid:3485655 |
Savel'ev VB | [Study of the mechanics and small-angle equatorial x-ray pattern of the frog skeletal muscle during transition and rigor at different temperatures]. | 1986 Nov-Dec | Biofizika | pmid:3492220 |
Heller KB et al. | Peroxidative membrane damage in human erythrocytes induced by a concerted action of iodoacetate, vanadate and ferricyanide. | 1987 | Biochim. Biophys. Acta | pmid:3496117 |
Abrahamson M et al. | Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin. | 1987 | J. Biol. Chem. | pmid:3496337 |
Hurwitz A | Drug uptake into everted intestinal sacs. II. Inhibition of secretion by hypertonicity. | 1979 | Am. J. Physiol. | pmid:35006 |
Ramp WK et al. | Effects of vitamin D deprivation and 1,25-dihydroxyvitamin D3 treatment on ion release from rat tibiae in vitro. | 1986 | Bone Miner | pmid:3508714 |
Gal S and Gottesman MM | The major excreted protein of transformed fibroblasts is an activable acid-protease. | 1986 | J. Biol. Chem. | pmid:3511049 |
Im JH et al. | Energy dependent insulin binding, internalization and degradation in isolated cardiac myocytes from normal and diabetic rats. | 1986 | J. Mol. Cell. Cardiol. | pmid:3514924 |
Milton DK and Chawla RK | Cotton dust contains proteolytic and elastolytic enzymes not inhibited by alpha-1-proteinase inhibitor. | 1986 | Am. J. Ind. Med. | pmid:3515917 |
Busturia A and Lagunas R | Catabolite inactivation of the glucose transport system in Saccharomyces cerevisiae. | 1986 | J. Gen. Microbiol. | pmid:3519857 |
Ishiura S et al. | Ingensin, a fatty acid-activated serine proteinase from rat liver cytosol. | 1986 | Biochim. Biophys. Acta | pmid:3524690 |
DiMattio J and Streitman J | Facilitated glucose transport across the retinal pigment epithelium of the bullfrog (Rana catesbeiana). | 1986 | Exp. Eye Res. | pmid:3525201 |
Turkiewicz M et al. | Purification and characterization of a proteinase from Euphausia superba Dana (Antarctic krill). | 1986 | Acta Biochim. Pol. | pmid:3532651 |
Plishker GA et al. | Involvement of a cytoplasmic protein in calcium-dependent potassium efflux in red blood cells. | 1986 | Am. J. Physiol. | pmid:3532815 |
Hynes WL and Tagg JR | Proteinase-related broad-spectrum inhibitory activity among group-A streptococci. | 1986 | J. Med. Microbiol. | pmid:3534275 |
Helm BA and Gunn JM | The effect of insulinomimetic agents on protein degradation in H35 hepatoma cells. | 1986 | Mol. Cell. Biochem. | pmid:3534545 |
Pacchiarini L et al. | Role of tumor proteinases in tumor cell-induced platelet aggregation. | 1986 | Invasion Metastasis | pmid:3536793 |
Reizer J and Saier MH | Mechanism and regulation of phosphate transport in Streptococcus pyogenes. | 1987 | J. Bacteriol. | pmid:3539921 |
Wakabayashi S et al. | [The effect of glucose concentrations on the functional maturation of monolayer-cultured B cells of neonatal rat pancreases]. | 1986 | Nihon Naibunpi Gakkai Zasshi | pmid:3542593 |
Shieh JH et al. | Purification and characterization of human colony-stimulating factor 1 from human pancreatic carcinoma (MIA PaCa-2) cells. | 1987 | Arch. Biochem. Biophys. | pmid:3545083 |
Takeda M et al. | Isolation, and catalytic and immunochemical properties of cathepsin D-like acid proteinase from rat erythrocytes. | 1986 | J. Biochem. | pmid:3546279 |
Wada A | Analysis of Escherichia coli ribosomal proteins by an improved two dimensional gel electrophoresis. II. Characterization of four new proteins. | 1986 | J. Biochem. | pmid:3553169 |
Yasuhara T and Ohashi A | New chelator-sensitive proteases in matrix of yeast mitochondria. | 1987 | Biochem. Biophys. Res. Commun. | pmid:3555485 |
Aurich H et al. | [Kinetics of membrane-bound aldehyde dehydrogenase from Acinetobacter calcoaceticus]. | 1987 | Biol. Chem. Hoppe-Seyler | pmid:3566912 |
Hermsdorf CL | Tripeptide-specific aminopeptidase from Escherichia coli AJ005. | 1978 | Biochemistry | pmid:356879 |
Jarroll EL et al. | Giardia lamblia: uptake of pyrimidine nucleosides. | 1987 | Exp. Parasitol. | pmid:3569473 |