Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Clements KM et al. | Cellular and histopathological changes in the infrapatellar fat pad in the monoiodoacetate model of osteoarthritis pain. | 2009 | Osteoarthr. Cartil. | pmid:19114312 |
Piscaer TM et al. | In vivo imaging of cartilage degeneration using microCT-arthrography. | 2008 | Osteoarthr. Cartil. | pmid:18342549 |
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Oestergaard S et al. | The utility of measuring C-terminal telopeptides of collagen type II (CTX-II) in serum and synovial fluid samples for estimation of articular cartilage status in experimental models of destructive joint diseases. | 2006 | Osteoarthr. Cartil. | pmid:16500121 |
Bove SE et al. | Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. | 2003 | Osteoarthr. Cartil. | pmid:14609535 |
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Moilanen LJ et al. | Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice--potential role of TRPA1 in osteoarthritis. | 2015 | Osteoarthr. Cartil. | pmid:26521748 |
McDougall JJ et al. | Lysophosphatidic acid provides a missing link between osteoarthritis and joint neuropathic pain. | 2017 | Osteoarthr. Cartil. | pmid:27651153 |
Thirunavukkarasu K et al. | Identification and pharmacological characterization of a novel inhibitor of autotaxin in rodent models of joint pain. | 2017 | Osteoarthr. Cartil. | pmid:27638130 |
Ono M et al. | Purification and characterization of a thiol-protease from Bacteroides gingivalis strain 381. | 1987 | Oral Microbiol. Immunol. | pmid:10870472 |
Ponte F et al. | Iodoacetic acid influence on the aerobic glycolysis in surviving retinae of normal rats and of carriers of inherited retinal degeneration. | 1974 | Ophthalmologica | pmid:4852565 |
Ono S and Hirano H | Riboflavin metabolism in the single lens of rat. | 1983 | Ophthalmic Res. | pmid:6634050 |
Delamere NA and Paterson CA | Studies on calcium regulation in relation to sodium-potassium balance in the rabbit lens. | 1982 | Ophthalmic Res. | pmid:7099540 |
Shen Y et al. | Effect of Guanabenz on Rat AMD Models and Rabbit Choroidal Blood Flow. | 2011 | Open Ophthalmol J | pmid:21633720 |
Sarigianni M et al. | Involvement of signaling molecules on na/h exchanger-1 activity in human monocytes. | 2010 | Open Cardiovasc Med J | pmid:21160910 |
Knock FE et al. | Effects of selected sulfhydryl inhibitors on nonhistone chromosomal proteins of HeLa cells. | 1975 | Oncology | pmid:1228540 |
Reyes-FermÃn LM et al. | Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death. | 2012 | Nutr Neurosci | pmid:22776704 |
Gallis JL et al. | A metabolic link between mitochondrial ATP synthesis and liver glycogen metabolism: NMR study in rats re-fed with butyrate and/or glucose. | 2011 | Nutr Metab (Lond) | pmid:21676253 |