Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Rheins MS and Filppi JA | Iodoacetate-induced inhibition and enhancement of spontaneous leukemia in AKR mice. | 1977 | J. Natl. Cancer Inst. | pmid:857029 |
Law RO | Factors affecting the distribution of chloride ions in rat renal outer medulla. | 1977 | J. Physiol. (Lond.) | pmid:856997 |
Walsh SB and Mantle TJ | Modification of mouse liver glutathione S-transferase Pi by iodoacetic acid. | 1995 | Biochem. Soc. Trans. | pmid:8566383 |
Hoban DJ and Lyric RM | Glutamate uptake in Thiobacillus novellus. | 1977 | Can. J. Microbiol. | pmid:856422 |
Lash LH et al. | ATP depletion by iodoacetate and cyanide in renal distal tubular cells. | 1996 | J. Pharmacol. Exp. Ther. | pmid:8558430 |
Raia CA et al. | Activation of Sulfolobus solfataricus alcohol dehydrogenase by modification of cysteine residue 38 with iodoacetic acid. | 1996 | Biochemistry | pmid:8555238 |
Ionescu E and Buresová O | Failure to elicit conditioned taste aversion by severe poisoning. | 1977 | Pharmacol. Biochem. Behav. | pmid:854518 |
Ma L et al. | Multiphasic modulation of signal transduction into T lymphocytes by monoiodoacetic acid as a sulfhydryl reagent. | 1995 | J. Cell. Biochem. | pmid:8530534 |
Chan CB et al. | Evidence for defective glucose sensing by islets of fa/fa obese Zucker rats. | 1993 | Can. J. Physiol. Pharmacol. | pmid:8513432 |
Kembhavi AA et al. | The two cysteine endopeptidases of legume seeds: purification and characterization by use of specific fluorometric assays. | 1993 | Arch. Biochem. Biophys. | pmid:8512309 |