Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Lee MH et al. | A monocysteine approach for probing the structure and interactions of the UmuD protein. | 1994 | J. Bacteriol. | pmid:8050995 |
Dransfield DT and Aprille JR | The influence of hypoxia and anoxia on distribution of adenine nucleotides in isolated hepatocytes. | 1994 | Arch. Biochem. Biophys. | pmid:8053677 |
Zhao W and Guénard H | Bronchial smooth muscle energetics: effect of iodoacetate and hypoxia. | 1994 | Respir Physiol | pmid:8059090 |
Koss KL and Grubbs RD | Elevated extracellular Mg2+ increases Mg2+ buffering through a Ca-dependent mechanism in cardiomyocytes. | 1994 | Am. J. Physiol. | pmid:8074196 |
Hazeu W | Some cultural and physiological aspects of methane-utilizing bacteria. | 1975 | Antonie Van Leeuwenhoek | pmid:808162 |
Wagner DR et al. | Existence and role of substrate cycling between AMP and adenosine in isolated rabbit cardiomyocytes under control conditions and in ATP depletion. | 1994 | Circulation | pmid:8087944 |
Gleisner JM and Blakley RL | The structure of dihydrofolate reductase. Identification of methionine residues carboxymethylated by iodoacetate with loss of catalytic activity. | 1975 | Eur. J. Biochem. | pmid:809271 |
Ide T et al. | Recovery of a DNA-protein complex in cultured mammalian cells from damage caused by 4-nitroquinoline 1-oxide. | 1975 | Cancer Res. | pmid:810243 |
Bickler PE et al. | Developmental changes in intracellular calcium regulation in rat cerebral cortex during hypoxia. | 1993 | J. Cereb. Blood Flow Metab. | pmid:8103057 |
Madl JE and Burgesser K | Adenosine triphosphate depletion reverses sodium-dependent, neuronal uptake of glutamate in rat hippocampal slices. | 1993 | J. Neurosci. | pmid:8105040 |
Zapun A et al. | Replacement of the active-site cysteine residues of DsbA, a protein required for disulfide bond formation in vivo. | 1994 | Biochemistry | pmid:8110795 |
Downs SM and Mastropolo AM | The participation of energy substrates in the control of meiotic maturation in murine oocytes. | 1994 | Dev. Biol. | pmid:8125183 |
Gao G and Fonda ML | Identification of an essential cysteine residue in pyridoxal phosphatase from human erythrocytes. | 1994 | J. Biol. Chem. | pmid:8132548 |
Webster KA et al. | Regulation of fos and jun immediate-early genes by redox or metabolic stress in cardiac myocytes. | 1994 | Circ. Res. | pmid:8137504 |
Stewart LC et al. | Simultaneous measurement of both lipid and lactate in isolated rat hearts by 1H NMR spectroscopy. | 1993 | Magn Reson Med | pmid:8139446 |
Borel JF and Feurer C | Chemotaxis of rabbit macrophages in vitro: inhibition by drugs. | 1975 | Experientia | pmid:814017 |
Siegel I et al. | Fc- and complement-receptor rosette-forming cell ratios in human tonsils and peripheral blood. | 1976 | Int. Arch. Allergy Appl. Immunol. | pmid:814104 |
Suzuki Y et al. | Purification and properties of extracellular alpha-glucosidase of a thermophile, Bacillus thermoglucosidus KP 1006. | 1976 | Biochim. Biophys. Acta | pmid:8145 |
Smith GL et al. | Relationship between intracellular pH and metabolite concentrations during metabolic inhibition in isolated ferret heart. | 1993 | J. Physiol. (Lond.) | pmid:8145137 |
Ivanics T et al. | Intracellular sodium in cardiomyocytes using 23Na nuclear magnetic resonance. | 1994 | Biochim. Biophys. Acta | pmid:8148390 |
Lai CY et al. | Chemistry of cholera toxin: the subunit structure. | 1976 | J. Infect. Dis. | pmid:815448 |
Bhatnagar A et al. | Human placental aldose reductase: role of Cys-298 in substrate and inhibitor binding. | 1994 | Biochim. Biophys. Acta | pmid:8155699 |
Semenova TV et al. | [Effect of various specific agents on the heat stability of human serum albumin]. | 1993 Sep-Oct | Ukr. Biokhim. Zh. | pmid:8160293 |
van Osch GJ et al. | Site-specific cartilage changes in murine degenerative knee joint disease induced by iodoacetate and collagenase. | 1994 | J. Orthop. Res. | pmid:8164088 |
Mason RM and Sweeney C | The relationship between proteoglycan synthesis in Swarm chondrocytes and pathways of cellular energy and UDP-sugar metabolism. | 1994 | Carbohydr. Res. | pmid:8181010 |
Khan IM et al. | Bovine pancreatic lipase. II. Stability and effect of activators and inhibitors. | 1976 | J. Dairy Sci. | pmid:818137 |
Habersetzer-Rochat C and Sampieri F | Structure-function relationships of scorpion neurotoxins. | 1976 | Biochemistry | pmid:819030 |
Plessel G et al. | m3G cap hypermethylation of U1 small nuclear ribonucleoprotein (snRNP) in vitro: evidence that the U1 small nuclear RNA-(guanosine-N2)-methyltransferase is a non-snRNP cytoplasmic protein that requires a binding site on the Sm core domain. | 1994 | Mol. Cell. Biol. | pmid:8196654 |
Weiss GB and Goodman FR | Distribution of a lanthanide (147 Pm) in vascular smooth muscle. | 1976 | J. Pharmacol. Exp. Ther. | pmid:820850 |
Duff SM et al. | An engineered change in the L-malate sensitivity of a site-directed mutant of sorghum phosphoenolpyruvate carboxylase: the effect of sequential mutagenesis and S-carboxymethylation at position 8. | 1993 | Arch. Biochem. Biophys. | pmid:8215415 |
Vessey DA and Benfatto AM | Chemical modification of bile acid: CoA ligase. | 1993 | Biochim. Biophys. Acta | pmid:8218381 |
Cairns SP and Dulhunty AF | Beta-adrenergic potentiation of E-C coupling increases force in rat skeletal muscle. | 1993 | Muscle Nerve | pmid:8232387 |
Hoedt-Schmidt S et al. | Histomorphological studies on the effect of recombinant human superoxide dismutase in biochemically induced osteoarthritis. | 1993 | Pharmacology | pmid:8234414 |
Lin PS | Sheep erythrocytes binding ability on a mouse renal adenocarcinoma cell line and its hybrid with human lymphocytes. | 1976 | Clin. Exp. Immunol. | pmid:825339 |
Coulin F et al. | Identification of Cys-150 in the active site of phosphomannose isomerase from Candida albicans. | 1993 | Biochemistry | pmid:8260497 |
Calonge ML et al. | Intracellular pH regulation in cecal epithelial cells from the chick. | 1993 | Biochim. Biophys. Acta | pmid:8274490 |
Baranova IP et al. | [Effect of iodoacetic acid and sodium fluoride on the development of lactic acid bacterium Streptococcus lactis, a producer of the polypeptide antibiotic nisin]. | 1976 | Nauchnye Doki Vyss Shkoly Biol Nauki | pmid:828507 |
Ganote CE et al. | Adenosine and A1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes. | 1993 | Cardiovasc. Res. | pmid:8287447 |
Yasuda T et al. | Human seminal deoxyribonuclease I (DNase I): purification, enzymological and immunological characterization and origin. | 1993 | Clin. Chim. Acta | pmid:8299220 |
Ito H et al. | Inactivation of porcine calcitonin by rat kidney microsome. | 1976 | Endocrinol. Jpn. | pmid:8306 |
Teng H et al. | Conserved cysteine residues of histidinol dehydrogenase are not involved in catalysis. Novel chemistry required for enzymatic aldehyde oxidation. | 1993 | J. Biol. Chem. | pmid:8314784 |
Russell JB | Effect of amino acids on the heat production and growth efficiency of Streptococcus bovis: balance of anabolic and catabolic rates. | 1993 | Appl. Environ. Microbiol. | pmid:8328799 |
Dunham J et al. | Prolonged effect of iodoacetate on articular cartilage and its modification by an anti-rheumatic drug. | 1993 | Int J Exp Pathol | pmid:8334078 |
van Osch GJ et al. | In vivo quantification of proteoglycan synthesis in articular cartilage of different topographical areas in the murine knee joint. | 1993 | J. Orthop. Res. | pmid:8340822 |
Liu SQ et al. | Identification of the reactive cysteine residue in human placenta aldose reductase. | 1993 | Biochim. Biophys. Acta | pmid:8343525 |
Mayorga LS et al. | Effect of pH and ATP on the equilibrium density of lysosomes. | 1993 | J. Cell. Physiol. | pmid:8344987 |
Igisu H et al. | Highly cooperative inhibition of acetylcholinesterase by pentachlorophenol in human erythrocytes. | 1993 | Biochem. Pharmacol. | pmid:8347128 |
Brooks SP and Storey KB | Control of glycolytic enzyme binding: effect of changing enzyme substrate concentrations on in vivo enzyme distributions. | 1993 | Mol. Cell. Biochem. | pmid:8350861 |
Greenwood SL et al. | Transtrophoblast and microvillus membrane potential difference in mature intermediate human placental villi. | 1993 | Am. J. Physiol. | pmid:8368275 |
Zhang ZY and Dixon JE | Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402. | 1993 | Biochemistry | pmid:8369304 |