Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Pain D010146 64 associated lipids
Lung Neoplasms D008175 171 associated lipids
Wounds and Injuries D014947 20 associated lipids
Burns D002056 34 associated lipids
Inflammation D007249 119 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Sarcoma 180 D012510 21 associated lipids
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
Stroke D020521 32 associated lipids
Starvation D013217 47 associated lipids
Hypocalcemia D006996 12 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Nerve Degeneration D009410 53 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Thrombocytopenia D013921 15 associated lipids
Hyperlipidemias D006949 73 associated lipids
Rickets D012279 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Byssinosis D002095 11 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Blindness D001766 6 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Arthralgia D018771 8 associated lipids
Osteophyte D054850 2 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Retinitis D012173 4 associated lipids
Theileriasis D013801 7 associated lipids
Muscle Cramp D009120 3 associated lipids
Rigor Mortis D012298 1 associated lipids
Thrombophilia D019851 6 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
pmid:
Xiong H et al. Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase. 1999 Biochemistry pmid:10029540
Harada T and Mino Y Some properties of p-coumarate decarboxylase from Cladosporium phlei. 1976 Can. J. Microbiol. pmid:10068
Boeck D and Grosch W [Glutathatione-dehydrogenase of wheat flour. Purification and properties (author's transl)]. 1976 Z Lebensm Unters Forsch pmid:1007616
Kinsland C et al. Overexpression of recombinant proteins with a C-terminal thiocarboxylate: implications for protein semisynthesis and thiamin biosynthesis. 1998 Protein Sci. pmid:10082383
Cooke RD et al. Purification and characterisation of polygalacturonases from a commercial Aspergillus niger preparation. 1976 Biochim. Biophys. Acta pmid:1009121
Rego AC et al. Distinct glycolysis inhibitors determine retinal cell sensitivity to glutamate-mediated injury. 1999 Neurochem. Res. pmid:10215508
Labib RS et al. Studies on extracellular proteases of Streptococcus sanguis. Purification and characterization of a human IgA1 specific protease. 1978 Biochim. Biophys. Acta pmid:102357
Sauermann G Studies on ribonucleic acid metabolism using nuclear columns. Release of rapidly labeled RNA from rat liver nuclei. 1976 Hoppe-Seyler's Z. Physiol. Chem. pmid:10244
Rector ES et al. A method for the preparation of protein-protein conjugates of predetermined composition. 1978 J. Immunol. Methods pmid:102705
Lokshina LA et al. [Isolation of a neutral histone-hydrolyzing protease from bovine spleen]. 1976 Biokhimiia pmid:1030647
Suzuki T An ultramicroscopic study on rigor mortis. 1976 Nov-Dec Forensic Sci pmid:1033890
Lu GW et al. Alteration of oxygen consumption and energy metabolism during repetitive exposure of mice to hypoxia. 1999 Neurochem. Res. pmid:10344590
Jörnvall H et al. Probe of beta-galactosidase structure with iodoacetate. Differential reactivity of thiol groups in wild-type and mutant forms of beta-galactosidase. 1978 Biochemistry pmid:103570
Duncan R and Lloyd JB Pinocytosis in the rat visceral yolk sac. Effects of temperature, metabolic inhibitors and some other modifiers. 1978 Biochim. Biophys. Acta pmid:103581
Hellsten Y The effect of muscle contraction on the regulation of adenosine formation in rat skeletal muscle cells. 1999 J. Physiol. (Lond.) pmid:10420012
Rivett DE and Peet DJ Fatty acids chemically bound to protein forms the hydrophic membrane of the hair cuticle. 1999 Exp. Dermatol. pmid:10439276
Yang XJ et al. Hypothalamic glucose sensor: similarities to and differences from pancreatic beta-cell mechanisms. 1999 Diabetes pmid:10480606
Suzuki S et al. Difference in the effect of phloridzin on alveolar fluid absorption in anesthetized rats and in ex vivo rat lungs. 1999 Jul-Aug Exp. Lung Res. pmid:10483523
Balijepalli S et al. Effect of thiol modification on brain mitochondrial complex I activity. 1999 Neurosci. Lett. pmid:10505616
Chave KJ et al. Site-directed mutagenesis establishes cysteine-110 as essential for enzyme activity in human gamma-glutamyl hydrolase. 1999 Biochem. J. pmid:10527932
Patel AB et al. Arginine acts as a protective and reversal agent against glycolytic inhibitors in spermatozoa. 1999 Physiol Chem Phys Med NMR pmid:10535103
Lai SL et al. Interprotein disulfide bonds formed during isolation process tighten the structure of the postsynaptic density. 1999 J. Neurochem. pmid:10537073
Dirksen TR et al. Effect of metabolic inhibitors on bone lipid synthesis from radioactive bases. 1975 Sep-Oct J. Dent. Res. pmid:1058850
Chang YS et al. Shear-induced increase in hydraulic conductivity in endothelial cells is mediated by a nitric oxide-dependent mechanism. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10634798
Malcolm CS et al. Characterization of iodoacetate-mediated neurotoxicity in vitro using primary cultures of rat cerebellar granule cells. 2000 Free Radic. Biol. Med. pmid:10656296
Sinclair CJ et al. Stimulation of nucleoside efflux and inhibition of adenosine kinase by A1 adenosine receptor activation. 2000 Biochem. Pharmacol. pmid:10660114
Kim JS and Southard JH Effect of phospholipase A2 inhibitors on the release of arachidonic acid and cell viability in cold-stored hepatocytes. 2000 Cryobiology pmid:10679147
Yoshioka K et al. Characteristics of monocarboxylates as energy substrates other than glucose in rat brain slices and the effect of selective glial poisoning - a 31P NMR study. 2000 Neurosci. Res. pmid:10683525
Nagano H and To KA Purification of collagenase and specificity of its related enzyme from Bacillus subtilis FS-2. 2000 Biosci. Biotechnol. Biochem. pmid:10705465
López M et al. The action of Lonomia achelous caterpillars venom on human factor V. 2000 Thromb. Res. pmid:10706938
Miyagi M and Misono KS Disulfide bond structure of the atrial natriuretic peptide receptor extracellular domain: conserved disulfide bonds among guanylate cyclase-coupled receptors. 2000 Biochim. Biophys. Acta pmid:10719172
Hung AC et al. ATP-stimulated c-fos and zif268 mRNA expression is inhibited by chemical hypoxia in a rat brain-derived type 2 astrocyte cell line, RBA-2. 2000 J. Cell. Biochem. pmid:10723097
Koiwai H et al. Functional expression of two Arabidopsis aldehyde oxidases in the yeast Pichia pastoris. 2000 J. Biochem. pmid:10739959
Rasmussen JT et al. Cysteines involved in the interconversion between dehydrogenase and oxidase forms of bovine xanthine oxidoreductase. 2000 J. Dairy Sci. pmid:10750108
Martínez AD and Sáez JC Regulation of astrocyte gap junctions by hypoxia-reoxygenation. 2000 Brain Res. Brain Res. Rev. pmid:10751675
Larionova NA [The lipid composition characteristics of the blood serum and aortic wall in the modelling of different types of arteriosclerosis]. 2000 Fiziol Zh pmid:10758833
Bordji K et al. Evidence for the presence of peroxisome proliferator-activated receptor (PPAR) alpha and gamma and retinoid Z receptor in cartilage. PPARgamma activation modulates the effects of interleukin-1beta on rat chondrocytes. 2000 J. Biol. Chem. pmid:10766862
Abdel-Fattah AF and Badawi MA Effect of some agents on the activity of cell-free progesterone 11 alpha-hydroxylase and 11 beta-hydroxylase from Aspergillus niger 12Y. 1978 Zentralbl Bakteriol Naturwiss pmid:107681
Collard WT et al. Synthesis of homogeneous glycopeptides and their utility as DNA condensing agents. 2000 Carbohydr. Res. pmid:10782299
Hüser J et al. Functional coupling between glycolysis and excitation-contraction coupling underlies alternans in cat heart cells. 2000 J. Physiol. (Lond.) pmid:10790159
Bailey JR et al. Maintenance of resting tension in the american eel (Anguilla rostrata L.) heart is dependent upon exogenous fuel and the sarcoplasmic reticulum. 2000 J. Exp. Zool. pmid:10797323
Lapko VN et al. Identification of an artifact in the mass spectrometry of proteins derivatized with iodoacetamide. 2000 J Mass Spectrom pmid:10797654
Pannicke T et al. A function of delayed rectifier potassium channels in glial cells: maintenance of an auxiliary membrane potential under pathological conditions. 2000 Brain Res. pmid:10799684
Kulik A et al. Ischemia but not anoxia evokes vesicular and Ca(2+)-independent glutamate release in the dorsal vagal complex in vitro. 2000 J. Neurophysiol. pmid:10805687
Yoshisue K et al. Pharmacokinetics and biological fate of 3-(2,2, 2-trimethylhydrazinium)propionate dihydrate (MET-88), a novel cardioprotective agent, in rats. 2000 Drug Metab. Dispos. pmid:10820142
Mulvany MJ Mechanical properties of frog skeletal muscles in iodoacetic acid rigor. 1975 J. Physiol. (Lond.) pmid:1082023
Sahin-Tóth M and Kaback HR Functional conservation in the putative substrate binding site of the sucrose permease from Escherichia coli. 2000 Biochemistry pmid:10821691
Alvarado RH et al. Chloride transport across isolated skin of Rana pipiens. 1975 Am. J. Physiol. pmid:1082245
Varel VH and Miller DN Effect of antimicrobial agents on livestock waste emissions. 2000 Curr. Microbiol. pmid:10827282
MacGregor RR et al. Isolation and characterization of porcine parathyroid cathepsin B. 1979 J. Biol. Chem. pmid:108278
de Vocht ML et al. Structural and functional role of the disulfide bridges in the hydrophobin SC3. 2000 J. Biol. Chem. pmid:10829014
Thibert P and Nicolet M [Tetanic fatigue and proximate post-tetanic recuperation in sartorius and flexor carpi radialis muscles of the male frog. Effects of iodoacetic acid (author's transl)]. 1976 J. Physiol. (Paris) pmid:1083432
Smirnov AV et al. [The role of glycolysis in the protective effect of amtizol during acute hypoxia]. 2000 Ross Fiziol Zh Im I M Sechenova pmid:10870220
Ono M et al. Purification and characterization of a thiol-protease from Bacteroides gingivalis strain 381. 1987 Oral Microbiol. Immunol. pmid:10870472
Fink R and Lüttgau HC An evaluation of the membrane constants and the potassium conductance in metabolically exhausted muscle fibres. 1976 J. Physiol. (Lond.) pmid:1087932
Arima K et al. Purification and some properties of an aminopeptidase from the seeds of Cannabis sativa. 2000 Biosci. Biotechnol. Biochem. pmid:10879480
Fukuda H and Kontani H Effects of metabolic inhibitors and ouabain on static afferent discharges from the isolated frog muscle spindle. 1976 Jpn. J. Pharmacol. pmid:1088168
Dumont M and Lemaire S Interactions of dynorphin A-(1-13) and nociceptin with cardiac D2 binding sites: inhibition of ischemia-evoked release of noradrenaline from synaptosomal-mitochondrial fractions. 2000 J. Mol. Cell. Cardiol. pmid:10900181
Chung YB et al. Partial characterization of a 17 kDa protein of Clonorchis sinensis. 2000 Korean J. Parasitol. pmid:10905071
de Groot K and Deshmukh A The subcutaneous implantation of xenogeneic decalcified teeth. 1975 J. Periodontol. pmid:1090722
Pace CS et al. Multiple metabolic functions of glucose in rat pancreatic islets. 1975 Diabetes pmid:1092580
Pace CS et al. Electrical and secretory manifestations of glucose and amino acid interactions in rat pancreatic islets. 1975 Diabetes pmid:1092581
Gusev GP and Agalakova NI [Na, K-Pump activation by isoproterenol, methylxanthines, and iodoacetate in erythrocytes of the frog Rana temporaria]. 2000 Mar-Apr Zh. Evol. Biokhim. Fiziol. pmid:10925849
Rheins MS et al. Effect of iodoacetate on the bone marrow immunocompetence of AKR mice. 1975 Cancer Res. pmid:1093673
Kanda-Nambu K et al. Isozymic nature of spore coat-associated alanine racemase of Bacillus subtilis. 2000 Amino Acids pmid:10949920
Spoerl E et al. Reversible permeability changes in the membrane of a yeast cell sugar compartment. 1975 J. Membr. Biol. pmid:1095751
Jiménez JC et al. Identification and partial characterization of excretory/secretory products with proteolytic activity in Giardia intestinalis. 2000 J. Parasitol. pmid:10958474
Winkler BS et al. Energy metabolism in human retinal Müller cells. 2000 Invest. Ophthalmol. Vis. Sci. pmid:10967082
Kwok KY et al. Strategies for maintaining the particle size of peptide DNA condensates following freeze-drying. 2000 Int J Pharm pmid:10967430
Urist MR et al. A chemosterilized antigen-extracted autodigested alloimplant for bone banks. 1975 Arch Surg pmid:1096848
Ikezawa H et al. Studies on phosphatidylinositol phosphodiesterase (phospholipase C type) of Bacillus cereus. I. purification, properties and phosphatase-releasing activity. 1976 Biochim. Biophys. Acta pmid:10986
van Wezel FM et al. Studies on the role of methionine in porcine pancreatic phospholipase A2. 1976 Biochim. Biophys. Acta pmid:10991
Massieu L et al. In vivo potentiation of glutamate-mediated neuronal damage after chronic administration of the glycolysis inhibitor iodoacetate. 2000 Exp. Neurol. pmid:10993686
Schrooyen PM et al. Partially carboxymethylated feather keratins. 1. Properties in aqueous systems. 2000 J. Agric. Food Chem. pmid:10995359
Menshikova EV et al. Low N-ethylmaleimide concentrations activate ryanodine receptors by a reversible interaction, not an alkylation of critical thiols. 2000 J. Biol. Chem. pmid:10998412
Khan SA and Iqbal J Polyclonal-antibody-mediated insolubilization and stabilization of papain. 2000 Biotechnol. Appl. Biochem. pmid:11001869
Choi MH et al. Purification of a 68-kDa cysteine proteinase from crude extract of Pneumocystis carinii. 2000 Korean J. Parasitol. pmid:11002651
Jez JM and Noel JP Mechanism of chalcone synthase. pKa of the catalytic cysteine and the role of the conserved histidine in a plant polyketide synthase. 2000 J. Biol. Chem. pmid:11006298
Sárkány Z et al. Characterization of the active site thiol group of rhinovirus 2A proteinase. 2000 FEBS Lett. pmid:11007981
Murphy DL et al. Occurrence, transport, and storage of octopamine in human thrombocytes. 1975 Clin. Pharmacol. Ther. pmid:1102236
Penraat JH et al. An evaluation of chemical arthrodesis of the proximal interphalangeal joint in the horse by using monoiodoacetate. 2000 Can. J. Vet. Res. pmid:11041498
Essenberg MK and Cooper RA Two ribose-5-phosphate isomerases from Escherichia coli K12: partial characterisation of the enzymes and consideration of their possible physiological roles. 1975 Eur. J. Biochem. pmid:1104357
Hashimoto S et al. Low oxygen tension during in vitro maturation is beneficial for supporting the subsequent development of bovine cumulus-oocyte complexes. 2000 Mol. Reprod. Dev. pmid:11066064
Dobbs PC et al. Identification of isoenzyme C as the principal carbonic anhydrase in human ciliary processes. 1979 Invest. Ophthalmol. Vis. Sci. pmid:110725
Yanagawa N et al. Riboflavin transport by isolated perfused rabbit renal proximal tubules. 2000 Am. J. Physiol., Cell Physiol. pmid:11078692
Gault NF et al. Effect of some electrical stimulation variables on wing flapping, post-mortem glycolysis and eating quality characteristics of broiler pectoralis major muscle. 2000 Br. Poult. Sci. pmid:11081423
De Busser HM et al. Identification of prenylcysteine carboxymethyltransferase in bovine adrenal chromaffin cells. 2000 Int. J. Biochem. Cell Biol. pmid:11084380
Schöfl C et al. Energetic requirement of carbachol-induced Ca2+ signaling in single mouse beta-cells. 2000 Endocrinology pmid:11089537
Fridlansky F and Milgrom E Interaction of uteroglobin with progesterone, 5alphapregnane-3,20-dione and estrogens. 1976 Endocrinology pmid:11093
Waterman IJ et al. Further characterization of a novel triacylglycerol hydrolase activity (pH 6.0 optimum) from microvillous membranes from human term placenta. 2000 Placenta pmid:11095931
Jezek P et al. Important amino acid residues of potato plant uncoupling protein (StUCP). 2000 Braz. J. Med. Biol. Res. pmid:11105092
Advani S and Roy KB Properties and secondary structure analysis of BanI endonuclease: identification of putative active site. 2000 Biochem. Biophys. Res. Commun. pmid:11112410
Sutherland M et al. Evidence for the presence of phospholipid hydroperoxide glutathione peroxidase in human platelets: implications for its involvement in the regulatory network of the 12-lipoxygenase pathway of arachidonic acid metabolism. 2001 Biochem. J. pmid:11115402
Gleisner JM and Blakley RL The structure of dihydrofolate reductase. I. Inactivation of bacterial dihydrofolate reductase concomitant with modification of a methionine residue at the active site. 1975 J. Biol. Chem. pmid:1112818
Marlewski M et al. Accelerated degradation of adenine nucleotide in erythrocytes of patients with chronic renal failure. 2000 Mol. Cell. Biochem. pmid:11129963
Pasqualini ME et al. COX and LOX eicosanoids modulate platelet activation and procoagulation induced by two murine cancer cells. 2000 Prostaglandins Leukot. Essent. Fatty Acids pmid:11133175
Shimada H et al. The effects of sulfhydryl blockers and metal ions on nickel accumulation by rat primary hepatocyte cultures. 2000 Toxicol. Lett. pmid:11137313
Mi H et al. Light-induced dynamic changes of NADPH fluorescence in Synechocystis PCC 6803 and its ndhB-defective mutant M55. 2000 Plant Cell Physiol. pmid:11148271
Prior BM et al. Fiber type and metabolic dependence of T2 increases in stimulated rat muscles. 2001 J. Appl. Physiol. pmid:11160061