Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Zhou X et al. | Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell Injury. | 2015 | Oxid Med Cell Longev | pmid:26557222 |
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James AD et al. | The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP. | 2015 | J. Biol. Chem. | pmid:26294767 |
Rahman W et al. | Electrophysiological evidence for voltage-gated calcium channel 2 (Cav2) modulation of mechano- and thermosensitive spinal neuronal responses in a rat model of osteoarthritis. | 2015 | Neuroscience | pmid:26247695 |
Jeong YJ et al. | Anti-Osteoarthritic Effects of the Litsea japonica Fruit in a Rat Model of Osteoarthritis Induced by Monosodium Iodoacetate. | 2015 | PLoS ONE | pmid:26244981 |
Ogbonna AC et al. | Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice. | 2015 | Age (Dordr) | pmid:25971876 |
Yassin NZ et al. | Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis. | 2015 | Drug Des Devel Ther | pmid:25792809 |
Wang S and Kaltashov IA | Identification of reduction-susceptible disulfide bonds in transferrin by differential alkylation using O(16)/O(18) labeled iodoacetic acid. | 2015 | J. Am. Soc. Mass Spectrom. | pmid:25716754 |
Sagar DR et al. | Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat. | 2015 | Osteoarthr. Cartil. | pmid:25623624 |
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Nan Y et al. | Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat. | 2013 | Sci China Life Sci | pmid:23657794 |
More AS et al. | Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. | 2013 | Pharmacol. Biochem. Behav. | pmid:23287799 |
La Porta C et al. | Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate. | 2013 | Pain | pmid:23199705 |
Song M et al. | Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. | 2013 | Arch. Toxicol. | pmid:23397585 |
Moon SJ et al. | Augmented chondroprotective effect of coadministration of celecoxib and rebamipide in the monosodium iodoacetate rat model of osteoarthritis. | 2013 | Arch. Pharm. Res. | pmid:23338062 |
Ogbonna AC et al. | Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice. | 2013 | Eur J Pain | pmid:23169679 |
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Liu X et al. | An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water. | 2013 | PLoS ONE | pmid:23613747 |