Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
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Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| ISSEKUTZ B et al. | Tissue metabolism and peripheral circulation. I. Effect of iodoacetic acid on the metabolism of muscles "in vivo". | 1951 | Arch Int Physiol | pmid:14857870 |
| ISSEKUTZ B et al. | Tissue metabolism and peripheral circulation. II. Effect of iodoacetic acid on peripheral circulation. | 1951 | Arch Int Physiol | pmid:14857871 |
| EBE M | Effect of glutamic acid, NaCN and monoiodoacetic acid on the potential changes of isolated toad's brain. | 1952 | Tohoku J. Exp. Med. | pmid:13005477 |
| Ochs S and Smith CB | Fast axoplasmic transport in mammalian nerve in vitro after block of glycolysis with iodoacetic acid. | 1971 | J. Neurochem. | pmid:4105449 |
| Georg RH et al. | Inhibition of glucose and tolbutamide-induced insulin release by iodoacetate and antimycin A. | 1971 | Endocrinology | pmid:4930775 |
| Milstein C and Frangione B | Disulphide bridges of the heavy chain of human immunoglobulin G2. | 1971 | Biochem. J. | pmid:4940472 |
| Glazer RI and Weber G | Iodoacetate inhibition of lactate production and lipid, protein, ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) synthesis in newborn rat brain cortex slices. | 1971 | Biochem. Pharmacol. | pmid:5137976 |
| Laiho KU et al. | Observations on cell volume, ultrastructure, mitochondrial conformation and vital-dye uptake in Ehrlich ascites tumor cells. Effects of inhibiting energy production and function of the plasma membrane. | 1971 | Am. J. Pathol. | pmid:5096366 |
| McGrath JJ and Jaeger J | Effect of iodoacetate on the carbon monoxide tolerance of the chick. | 1971 | Respir Physiol | pmid:5578728 |
| Godfraind JM et al. | Actions of dinitrophenol and some other metabolic inhibitors on cortical neurones. | 1971 | J. Physiol. (Lond.) | pmid:5579652 |
| Boullin DJ and O'Brien RA | Accumulation of quinidine by human blood platelets: effects on platelet ultrastructure and 5-hydroxytryptamine. | 1971 | Br. J. Pharmacol. | pmid:5580696 |
| Skelton CL et al. | Mechanochemistry of cardiac muscle. V. Influence of thyroid state on energy utilization. | 1971 | J. Clin. Invest. | pmid:5545115 |
| Konings AW | The influence of iodoacetate on the mechanism of nuclear glucose oxidation. | 1971 | Experientia | pmid:5546629 |
| Sabri MI and Ochs S | Inhibition of glyceraldehyde-3-phosphate dehydrogenase in mammalian nerve by iodoacetic acid. | 1971 | J. Neurochem. | pmid:4398402 |
| Noguti T et al. | Radiosensitization with iodine compounds. 3. Macromolecular synthesis and repair in Bacillus subtilis irradiated in the presence of iodoacetic acid, potassium iodide or potassium iodate. | 1971 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:4995962 |
| Romero PJ and Whittam R | The control by internal calcium of membrane permeability to sodium and potassium. | 1971 | J. Physiol. (Lond.) | pmid:4996367 |
| Cohen AB and Cline MJ | The human alveolar macrophage: isolation, cultivation in vitro, and studies of morphologic and functional characteristics. | 1971 | J. Clin. Invest. | pmid:4996883 |
| Mudd JB et al. | Inhibition of glycolipid biosynthesis in chloroplasts by ozone and sulfhydryl reagents. | 1971 | Plant Physiol. | pmid:16657793 |
| Klepper L et al. | Generation of reduced nicotinamide adenine dinucleotide for nitrate reduction in green leaves. | 1971 | Plant Physiol. | pmid:16657841 |
| Schacter B et al. | Involvement of Photosynthetic Carbon Reduction Cycle Intermediates in CO(2) Fixation and O(2) Evolution by Isolated Chloroplasts. | 1971 | Plant Physiol. | pmid:16657865 |