Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Machalińska A et al. | Sodium iodate selectively injuries the posterior pole of the retina in a dose-dependent manner: morphological and electrophysiological study. | 2010 | Neurochem. Res. | pmid:20725778 |
Ferreira-Gomes J et al. | Phenotypic alterations of neurons that innervate osteoarthritic joints in rats. | 2010 | Arthritis Rheum. | pmid:20722015 |
Fang M et al. | Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat. | 2010 | Mol. Cancer | pmid:20704698 |
Li M et al. | A novel function for vimentin: the potential biomarker for predicting melanoma hematogenous metastasis. | 2010 | J. Exp. Clin. Cancer Res. | pmid:20701774 |
Xu YD et al. | The early asthmatic response is associated with glycolysis, calcium binding and mitochondria activity as revealed by proteomic analysis in rats. | 2010 | Respir. Res. | pmid:20691077 |
Garner OB et al. | Endothelial galectin-1 binds to specific glycans on nipah virus fusion protein and inhibits maturation, mobility, and function to block syncytia formation. | 2010 | PLoS Pathog. | pmid:20657665 |
Swearingen CA et al. | A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs. | 2010 | Osteoarthr. Cartil. | pmid:20633676 |
Strassle BW et al. | Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease. | 2010 | Osteoarthr. Cartil. | pmid:20633675 |
Ochrietor JD et al. | The 2M6 antigen is a Müller cell-specific intracellular membrane-associated protein of the sarcolemmal-membrane-associated protein family and is also TopAP. | 2010 | Mol. Vis. | pmid:20577597 |
Im HJ et al. | Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model. | 2010 | Arthritis Rheum. | pmid:20556813 |
Castillo-Romero A et al. | Rab11 and actin cytoskeleton participate in Giardia lamblia encystation, guiding the specific vesicles to the cyst wall. | 2010 | PLoS Negl Trop Dis | pmid:20532229 |
Ivannikov MV et al. | Calcium clearance and its energy requirements in cerebellar neurons. | 2010 | Cell Calcium | pmid:20510449 |
Dalal P and Romani A | Adenosine triphosphate depletion by cyanide results in a Na(+)-dependent Mg(2+) extrusion from liver cells. | 2010 | Metab. Clin. Exp. | pmid:20494376 |
Gigliobianco T et al. | Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. | 2010 | BMC Microbiol. | pmid:20492686 |
Tsai JH et al. | The protection of hepatocyte cells from the effects of oxidative stress by treatment with vitamin E in conjunction with DTT. | 2010 | J. Biomed. Biotechnol. | pmid:20490359 |
Lim KM et al. | Low-level mercury can enhance procoagulant activity of erythrocytes: a new contributing factor for mercury-related thrombotic disease. | 2010 | Environ. Health Perspect. | pmid:20308036 |
Shirran SL and Botting CH | A comparison of the accuracy of iTRAQ quantification by nLC-ESI MSMS and nLC-MALDI MSMS methods. | 2010 | J Proteomics | pmid:20230925 |
McGaraughty S et al. | TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. | 2010 | Mol Pain | pmid:20205719 |
Mann K et al. | Phosphoproteomes of Strongylocentrotus purpuratus shell and tooth matrix: identification of a major acidic sea urchin tooth phosphoprotein, phosphodontin. | 2010 | Proteome Sci | pmid:20181113 |
Calmettes G et al. | Improved energy supply regulation in chronic hypoxic mouse counteracts hypoxia-induced altered cardiac energetics. | 2010 | PLoS ONE | pmid:20174637 |
Edes K et al. | JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1. | 2010 | PLoS ONE | pmid:20098717 |
Kuduk SD et al. | Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567. | 2010 | ACS Chem Neurosci | pmid:22778804 |
Noyes PD et al. | Characterizing the in vitro hepatic biotransformation of the flame retardant BDE 99 by common carp. | 2010 | Aquat. Toxicol. | pmid:20080306 |
Kuzinski J et al. | The vacuolar-type H-ATPase in ovine rumen epithelium is regulated by metabolic signals. | 2010 | J. Biomed. Biotechnol. | pmid:20069127 |
Collas A et al. | 2-(4-Formyl-2,6-dimeth-oxy-phenoxy)-acetic acid. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21589164 |
Evans C | [3-(Iodo-acetamido)prop-yl]triphenyl-phospho-nium tetra-phenyl-borate. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21579806 |
Qiao YL | [Perspective of cervical cancer prevention and control in developing countries and areas]. | 2010 | Chin J Cancer | pmid:20038301 |
González-Teuber M et al. | Glucanases and chitinases as causal agents in the protection of Acacia extrafloral nectar from infestation by phytopathogens. | 2010 | Plant Physiol. | pmid:20023149 |
Okamoto M and Atsuta Y | Cartilage degeneration is associated with augmented chemically-induced joint pain in rats: a pilot study. | 2010 | Clin. Orthop. Relat. Res. | pmid:20013164 |
Coombs PJ et al. | Identification of novel contributions to high-affinity glycoprotein-receptor interactions using engineered ligands. | 2010 | J. Mol. Biol. | pmid:20004209 |
Sniekers YH et al. | Estrogen modulates iodoacetate-induced gene expression in bovine cartilage explants. | 2010 | J. Orthop. Res. | pmid:19953602 |
North SJ et al. | Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity. | 2010 | J. Biol. Chem. | pmid:19951948 |
Liviac D et al. | Genotoxicity testing of three monohaloacetic acids in TK6 cells using the cytokinesis-block micronucleus assay. | 2010 | Mutagenesis | pmid:20547559 |
Miao J et al. | 2-Oxo-2,3-dihydro-1H-imidazo[1,2-a]pyridinium iodide. | 2010 | Acta Crystallogr Sect E Struct Rep Online | pmid:21580362 |
Sagar DR et al. | Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. | 2010 | Arthritis Rheum. | pmid:20722027 |
Chambers JE et al. | The reduction potential of the active site disulfides of human protein disulfide isomerase limits oxidation of the enzyme by Ero1α. | 2010 | J. Biol. Chem. | pmid:20657012 |
Yoshimi E et al. | Sustained analgesic effect of the Rho kinase inhibitor AS1892802 in rat models of chronic pain. | 2010 | J. Pharmacol. Sci. | pmid:20710117 |
Rao Y et al. | Mapping of selenium metabolic pathway in yeast by liquid chromatography-Orbitrap mass spectrometry. | 2010 | Anal. Chem. | pmid:20825195 |
Wada M and Shirahata A | Conformational stabilization of rat s-adenosylmethionine decarboxylase by putrescine. | 2010 | Biol. Pharm. Bull. | pmid:21048303 |
Kawase N et al. | Collagenolytic activity in sonic extracts of Tannerella forsythia. | 2010 | Arch. Oral Biol. | pmid:20619781 |
Puntel RL et al. | Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening. | 2010 | Toxicol. Sci. | pmid:20573786 |
Liu H et al. | Domain-level stability of an antibody monitored by reduction, differential alkylation, and mass spectrometry analysis. | 2010 | Anal. Biochem. | pmid:20152794 |
Chu CR et al. | In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage. | 2010 | J Bone Joint Surg Am | pmid:20194318 |
RodrÃguez SB et al. | Cysteine 351 is an essential nucleophile in catalysis by Porphyromonas gingivalis peptidylarginine deiminase. | 2010 | Arch. Biochem. Biophys. | pmid:20850413 |
Saudemont A et al. | Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm. | 2010 | PLoS Genet. | pmid:21203442 |
Catterall JB et al. | Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254). | 2010 | Arthritis Res. Ther. | pmid:21194441 |
Peyfoon E et al. | The S-layer glycoprotein of the crenarchaeote Sulfolobus acidocaldarius is glycosylated at multiple sites with chitobiose-linked N-glycans. | 2010 | Archaea | pmid:20936123 |
Sniekers YH et al. | Oestrogen is important for maintenance of cartilage and subchondral bone in a murine model of knee osteoarthritis. | 2010 | Arthritis Res. Ther. | pmid:20923566 |
Bittner CX et al. | High resolution measurement of the glycolytic rate. | 2010 | Front Neuroenergetics | pmid:20890447 |
Schuelert N et al. | Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain. | 2010 | Osteoarthr. Cartil. | pmid:20863899 |
Eby WM et al. | Hyperbolastic modeling of tumor growth with a combined treatment of iodoacetate and dimethylsulphoxide. | 2010 | BMC Cancer | pmid:20863400 |
Li SC et al. | Chicken model of steroid-induced bone marrow adipogenesis using proteome analysis: a preliminary study. | 2010 | Proteome Sci | pmid:20840762 |
Lin D et al. | Cysteinyl peptide capture for shotgun proteomics: global assessment of chemoselective fractionation. | 2010 | J. Proteome Res. | pmid:20731415 |
Shi H and Adams C | Rapid IC-ICP/MS method for simultaneous analysis of iodoacetic acids, bromoacetic acids, bromate, and other related halogenated compounds in water. | 2009 | Talanta | pmid:19559915 |
Ziółkowski P et al. | Immunohistochemical and proteomic evaluation of nuclear ubiquitous casein and cyclin-dependent kinases substrate in invasive ductal carcinoma of the breast. | 2009 | J. Biomed. Biotechnol. | pmid:20069058 |
Rogers DW et al. | Transglutaminase-mediated semen coagulation controls sperm storage in the malaria mosquito. | 2009 | PLoS Biol. | pmid:20027206 |
Wilson CG et al. | Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications. | 2009 | Arthritis Res. Ther. | pmid:19919704 |
Galli GL et al. | Ca2+ cycling in cardiomyocytes from a high-performance reptile, the varanid lizard (Varanus exanthematicus). | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19812356 |
Bar-Yehuda S et al. | Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment. | 2009 | Arthritis Rheum. | pmid:19790055 |
Tolonen AC et al. | Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367. | 2009 | Mol. Microbiol. | pmid:19775243 |
Castillo-Romero A et al. | Participation of actin on Giardia lamblia growth and encystation. | 2009 | PLoS ONE | pmid:19774081 |
Lur G et al. | Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors. | 2009 | Curr. Biol. | pmid:19765991 |
Charles RC et al. | Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium. | 2009 | PLoS ONE | pmid:19746165 |
Jones DP and Liang Y | Measuring the poise of thiol/disulfide couples in vivo. | 2009 | Free Radic. Biol. Med. | pmid:19715755 |
Volate S et al. | TJ-41 Induces Apoptosis and Potentiates the Apoptotic Effects of 5-FU in Breast Cancer Cell Lines. | 2009 | J Oncol | pmid:19710936 |
Burow LC et al. | Induction of membrane permeability in Escherichia coli mediated by lysis protein of the ColE7 operon. | 2009 | FEMS Microbiol. Lett. | pmid:19673051 |
Ahamed J et al. | In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1. | 2009 | PLoS ONE | pmid:19672301 |
Rahman W et al. | Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain. | 2009 | Mol Pain | pmid:19664204 |
Santos SB et al. | The use of antibiotics to improve phage detection and enumeration by the double-layer agar technique. | 2009 | BMC Microbiol. | pmid:19627589 |
Burow LC et al. | Anaerobic central metabolic pathways active during polyhydroxyalkanoate production in uncultured cluster 1 Defluviicoccus enriched in activated sludge communities. | 2009 | FEMS Microbiol. Lett. | pmid:19622073 |
Schmidt MM and Dringen R | Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes. | 2009 | Front Neuroenergetics | pmid:19584905 |
van Hell AJ et al. | Stabilization of peptide vesicles by introducing inter-peptide disulfide bonds. | 2009 | Pharm. Res. | pmid:19582551 |
Morita H et al. | Heterologous expression and characterization of CpI, OcpA, and novel serine-type carboxypeptidase OcpB from Aspergillus oryzae. | 2009 | Appl. Microbiol. Biotechnol. | pmid:19557408 |
Fagerholm S et al. | Rapid insulin-dependent endocytosis of the insulin receptor by caveolae in primary adipocytes. | 2009 | PLoS ONE | pmid:19543529 |
Royter M et al. | Thermostable lipases from the extreme thermophilic anaerobic bacteria Thermoanaerobacter thermohydrosulfuricus SOL1 and Caldanaerobacter subterraneus subsp. tengcongensis. | 2009 | Extremophiles | pmid:19579003 |
Nykopp TK et al. | Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan content. | 2009 | BMC Cancer | pmid:19435493 |
Powlesland AS et al. | Targeted glycoproteomic identification of cancer cell glycosylation. | 2009 | Glycobiology | pmid:19433864 |
Harvey VL and Dickenson AH | Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice. | 2009 | Mol Pain | pmid:19379487 |
Nochez Y et al. | Acute and late-onset optic atrophy due to a novel OPA1 mutation leading to a mitochondrial coupling defect. | 2009 | Mol. Vis. | pmid:19325939 |
Gandhi S et al. | PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. | 2009 | Mol. Cell | pmid:19285945 |
Sandercock DA et al. | Changes in muscle cell cation regulation and meat quality traits are associated with genetic selection for high body weight and meat yield in broiler chickens. | 2009 | Genet. Sel. Evol. | pmid:19284683 |
Wei WC et al. | Requirement of focal adhesion kinase in branching tubulogenesis. | 2009 | J. Biomed. Sci. | pmid:19272169 |
Lassiter C et al. | HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction. | 2009 | AIDS Res Ther | pmid:19193217 |
Sintov AC et al. | Cutaneous biotransformation of N-(4-bromobenzoyl)-S,S-dimethyliminosulfurane and its product, 4-bromobenzamide, leading to percutaneous penetration enhancement of drugs: initial evidence using hydrocortisone. | 2009 | J Control Release | pmid:18950667 |
Clements KM et al. | Cellular and histopathological changes in the infrapatellar fat pad in the monoiodoacetate model of osteoarthritis pain. | 2009 | Osteoarthr. Cartil. | pmid:19114312 |
Santos-Rosa H et al. | Histone H3 tail clipping regulates gene expression. | 2009 | Nat. Struct. Mol. Biol. | pmid:19079264 |
Devalaraja-Narashimha K and Padanilam BJ | PARP-1 inhibits glycolysis in ischemic kidneys. | 2009 | J. Am. Soc. Nephrol. | pmid:19056868 |
Uyama T et al. | The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase type. | 2009 | J. Lipid Res. | pmid:19047760 |
Ren J et al. | Identification and quantification of 2',3'-cAMP release by the kidney. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19033554 |
Bongard RD et al. | Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells. | 2009 | Free Radic. Biol. Med. | pmid:18848878 |
Babu P et al. | Structural characterisation of neutrophil glycans by ultra sensitive mass spectrometric glycomics methodology. | 2009 | Glycoconj. J. | pmid:18587645 |
Cialdai C et al. | Effect of Intra-articular 4-(S)-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl} piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a kinin B2 receptor antagonist, on nociceptive response in monosodium iodoacetate-induced experimental osteoarthritis in rats. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19745108 |
González-Reyes S et al. | Neuroprotective role of heme-oxygenase 1 against iodoacetate-induced toxicity in rat cerebellar granule neurons: Role of bilirubin. | 2009 | Free Radic. Res. | pmid:19177228 |
Chumsae C et al. | Identification and localization of unpaired cysteine residues in monoclonal antibodies by fluorescence labeling and mass spectrometry. | 2009 | Anal. Chem. | pmid:19572546 |
Baragi VM et al. | A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models. | 2009 | Arthritis Rheum. | pmid:19565489 |
Suna H et al. | Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death. | 2009 | Bioorg. Med. Chem. | pmid:19414266 |
Shani V et al. | Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia. | 2009 | J. Mol. Neurosci. | pmid:18584337 |
Pilarski JQ et al. | Effects of aerobic and anaerobic metabolic inhibitors on avian intrapulmonary chemoreceptors. | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19297545 |
Lehner C et al. | Nitric oxide suppresses growth and development in the unicellular green alga Micrasterias denticulata. | 2009 | J. Plant Physiol. | pmid:18455833 |
PROCHAZKOVA M et al. | Increased gene expression and production of spinal cyclooxygenase 1 and 2 during experimental osteoarthritis pain. | 2009 | Physiol Res | pmid:18637715 |