Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Umbach AL and Siedow JN | The reaction of the soybean cotyledon mitochondrial cyanide-resistant oxidase with sulfhydryl reagents suggests that alpha-keto acid activation involves the formation of a thiohemiacetal. | 1996 | J. Biol. Chem. | pmid:8798784 |
Sammut EB and Kannegieter NJ | Use of sodium monoiodoacetate to fuse the distal hock joints in horses. | 1995 | Aust. Vet. J. | pmid:8787522 |
Barrigon S et al. | Characterization of the calcium overload in cultured neonatal rat cardiomyocytes under metabolic inhibition. | 1996 | J. Mol. Cell. Cardiol. | pmid:8782074 |
Hegy GB et al. | Carboxymethylation of the human estrogen receptor ligand-binding domain-estradiol complex: HPLC/ESMS peptide mapping shows that cysteine 447 does not react with iodoacetic acid. | 1996 | Steroids | pmid:8776799 |
Kanaani J et al. | Probing the active site of Tritrichomonas foetus hypoxanthine-guanine-xanthine phosphoribosyltransferase using covalent modification of cysteine residues. | 1996 | Eur. J. Biochem. | pmid:8774725 |
Wu Y et al. | Alterations in reactive oxygen, pH, and calcium in astrocytoma cells during lethal injury. | 1996 | Am. J. Physiol. | pmid:8772436 |
Ito Y et al. | Oxidative stress increases glyceraldehyde-3-phosphate dehydrogenase mRNA levels in isolated rabbit aorta. | 1996 | Am. J. Physiol. | pmid:8769737 |
Ballanyi K et al. | Functional relevance of anaerobic metabolism in the isolated respiratory network of newborn rats. | 1996 | Pflugers Arch. | pmid:8764977 |
Lawson SL et al. | Effects of both shortening and lengthening the active site nucleophile of Bacillus circulans xylanase on catalytic activity. | 1996 | Biochemistry | pmid:8756474 |
Dekker LR et al. | Intracellular Ca2+, intercellular electrical coupling, and mechanical activity in ischemic rabbit papillary muscle. Effects of preconditioning and metabolic blockade. | 1996 | Circ. Res. | pmid:8756000 |
Ishimizu T et al. | Identification of histidine 31 and cysteine 95 in the active site of self-incompatibility associated S6-RNase in Nicotiana alata. | 1995 | J. Biochem. | pmid:8749320 |
Bersinger NA et al. | Pregnancy-associated plasma protein A (PAPP-A): measurement by highly sensitive and specific enzyme immunoassay, importance of first-trimester serum determinations, and stability studies. | 1995 | Reprod. Fertil. Dev. | pmid:8743141 |
Liang CS | Metabolic control of circulation. Effects of iodoacetate and fluoroacetate. | 1977 | J. Clin. Invest. | pmid:874090 |
Morel MH and Bonicel J | Determination of the number of cysteine residues in high molecular weight subunits of wheat glutenin. | 1996 | Electrophoresis | pmid:8740165 |
Springer TA et al. | Submit and disulfide structure of monomeric and dimeric forms of detergent-soluble HLA antigens. | 1977 | J. Biol. Chem. | pmid:873911 |
Six S et al. | Reactivity of the N-terminal cysteine residues in active and inactive forms of FNR, and O2-responsive, Fe containing transcriptional regulator of Escherichia coli. | 1996 | J. Inorg. Biochem. | pmid:8729797 |
Hunter ES and Tugman JA | Inhibitors of glycolytic metabolism affect neurulation-staged mouse conceptuses in vitro. | 1995 | Teratology | pmid:8711618 |
Vospel'nikova ND et al. | [Structural studies on D-glyceraldehyde-3-phosphate dehydrogenase from rat skeletal muscle]. | 1977 | Biokhimiia | pmid:870089 |
Barnett DK and Bavister BD | Inhibitory effect of glucose and phosphate on the second cleavage division of hamster embryos: is it linked to metabolism? | 1996 | Hum. Reprod. | pmid:8671182 |
Boehm EA et al. | The utilisation of creatine and its analogues by cytosolic and mitochondrial creatine kinase. | 1996 | Biochim. Biophys. Acta | pmid:8664304 |