Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Glycogen Storage Disease D006008 4 associated lipids
Blindness D001766 6 associated lipids
Rickets D012279 6 associated lipids
Thrombophilia D019851 6 associated lipids
Theileriasis D013801 7 associated lipids
Arthralgia D018771 8 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Byssinosis D002095 11 associated lipids
Hypocalcemia D006996 12 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Ralat LA and Colman RF Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. 2006 Biochemistry pmid:17029404
Aiedeh KM et al. Effect of ionic crosslinking on the drug release properties of chitosan diacetate matrices. 2007 J Pharm Sci pmid:17031867
Keough DT et al. Localization of the 5-phospho-alpha-D-ribosyl-1-pyrophosphate binding site of human hypoxanthine-guanine phosphoribosyltransferase. 1991 Biochim. Biophys. Acta pmid:1705826
Rogel A et al. The neuroprotective adenosine-activated signal transduction pathway involves activation of phospholipase C. 2006 Nucleosides Nucleotides Nucleic Acids pmid:17065107
Duewelhenke N et al. Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. 2007 Antimicrob. Agents Chemother. pmid:17088489
Laiho KU and Trump BF Mitochondrial changes, ion and water shifts in the cellular injury of ehrlich ascites tumor cells. 1975 Beitr Pathol pmid:170904
Gover TD et al. Calcium regulation in individual peripheral sensory nerve terminals of the rat. 2007 J. Physiol. (Lond.) pmid:17095566
Mejía-Toiber J et al. D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo. 2006 Neurochem. Res. pmid:17115265
Liang L et al. Purification and characterization of trehalose-6-phosphate synthase from Saccharomycopsis fibuligera A11. 2006 Indian J. Biochem. Biophys. pmid:17133735
Munger J et al. Dynamics of the cellular metabolome during human cytomegalovirus infection. 2006 PLoS Pathog. pmid:17173481
Hashimoto S et al. Dependence of platelet adenyl cyclase system on oxidative phosphorylation. 1975 Thromb Diath Haemorrh pmid:171798
pmid:17189169
Morgan A and Maliga P Rapid chloroplast segregation and recombination of mitochondrial DNA in Brassica cybrids. 1987 Mol. Gen. Genet. pmid:17191340
pmid:17206661
pmid:17218122
Kito Y and Suzuki H Effects of temperature on pacemaker potentials in the mouse small intestine. 2007 Pflugers Arch. pmid:17235578
Menczel L et al. Effect of radiation dosage on efficiency of chloroplast transfer by protoplast fusion in Nicotiana. 1982 Genetics pmid:17246066
Raffin CN et al. Glycolysis, oxidative metabolism, and brain potassium ion clearance. 1992 J. Cereb. Blood Flow Metab. pmid:1727141
Ivanavicius SP et al. Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF-3 and pharmacological characterisation. 2007 Pain pmid:17276007
Appleton CT et al. Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis. 2007 Arthritis Res. Ther. pmid:17284317
Beyreuther B et al. Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain. 2007 Arthritis Res. Ther. pmid:17284318
pmid:17299207
pmid:17301007
Gatson JW and Singh M Activation of a membrane-associated androgen receptor promotes cell death in primary cortical astrocytes. 2007 Endocrinology pmid:17303658
Pot DA and Dixon JE Active site labeling of a receptor-like protein tyrosine phosphatase. 1992 J. Biol. Chem. pmid:1730581
Zherebtsov NA and Krayushkina EA [Some properties of proteases of the mould Mucor pusillus-917]. 1975 May-Jun Prikl. Biokhim. Mikrobiol. pmid:1731
Buttle DJ et al. Inhibition of interleukin 1-stimulated cartilage proteoglycan degradation by a lipophilic inactivator of cysteine endopeptidases. 1992 Biochem. J. pmid:1731753
Aromolaran AS et al. Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. 2007 Am. J. Physiol., Cell Physiol. pmid:17344311
pmid:17345116
Silva CM and Cidlowski JA The effect of oxidation/reduction on the charge heterogeneity of the human glucocorticoid receptor. 1992 J. Steroid Biochem. Mol. Biol. pmid:1734932
Zhang ZY et al. Covalent modification and active site-directed inactivation of a low molecular weight phosphotyrosyl protein phosphatase. 1992 Biochemistry pmid:1737025
Notsu T et al. Blockade of the ATP-sensitive K+ channel by 5-hydroxydecanoate in guinea pig ventricular myocytes. 1992 J. Pharmacol. Exp. Ther. pmid:1738118
Marinkovic DV and Marinkovic JN Purification of two hexosaminidases from human kidney. 1977 Biochem. J. pmid:17390
Neugebauer V et al. Techniques for assessing knee joint pain in arthritis. 2007 Mol Pain pmid:17391515
pmid:17447005
Lew VL et al. Effects of age-dependent membrane transport changes on the homeostasis of senescent human red blood cells. 2007 Blood pmid:17456724
Nakai T et al. Proteolysis of canine apolipoprotein by acid proteases in canine liver lysosomes. 1976 Biochim. Biophys. Acta pmid:174745
Barve RA et al. Transcriptional profiling and pathway analysis of monosodium iodoacetate-induced experimental osteoarthritis in rats: relevance to human disease. 2007 Osteoarthr. Cartil. pmid:17500014
pmid:17545192
Dray A and Read SJ Arthritis and pain. Future targets to control osteoarthritis pain. 2007 Arthritis Res. Ther. pmid:17561993
Perks AM et al. Lung liquid production by in vitro lungs from fetal guinea pigs: studies with metabolic inhibitors. 1991 Can. J. Physiol. Pharmacol. pmid:1756423
pmid:17571896
pmid:17583780
pmid:17609869
Lowenhaupt RW et al. Factors which influence blood platelet migration. 1977 J. Lab. Clin. Med. pmid:17642
Chen F et al. Effects of metabolic inhibition on conduction, Ca transients, and arrhythmia vulnerability in embryonic mouse hearts. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17660398
pmid:17687604
Froelich JM and Reid GE Mechanisms for the proton mobility-dependent gas-phase fragmentation reactions of S-alkyl cysteine sulfoxide-containing peptide ions. 2007 J. Am. Soc. Mass Spectrom. pmid:17689096
pmid:17691843
Serban MA and Prestwich GD Synthesis of hyaluronan haloacetates and biology of novel cross-linker-free synthetic extracellular matrix hydrogels. 2007 Biomacromolecules pmid:17696398