Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Hyperalgesia D006930 42 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hypocalcemia D006996 12 associated lipids
Inflammation D007249 119 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Merker MP et al. Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells. 2002 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11741813
Harrison GJ et al. Glycolytic buffering affects cardiac bioenergetic signaling and contractile reserve similar to creatine kinase. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12714331
Zhou L et al. Impact of anaerobic glycolysis and oxidative substrate selection on contractile function and mechanical efficiency during moderate severity ischemia. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18660443
Raddatz E et al. Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21193588
Chen F et al. Effects of metabolic inhibition on conduction, Ca transients, and arrhythmia vulnerability in embryonic mouse hearts. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17660398
Singla DK et al. TGF-β2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21297031
Okamoto K et al. ATP from glycolysis is required for normal sodium homeostasis in resting fast-twitch rodent skeletal muscle. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11500303
Ruff RL and Weissman J Iodoacetate-induced contracture in rat skeletal muscle: possible role of ADP. 1991 Am. J. Physiol. pmid:1951670
Barry WH et al. Effects of graded hypoxia on contraction of cultured chick embryo ventricular cells. 1980 Am. J. Physiol. pmid:7435640
Ito Y et al. Oxidative stress increases glyceraldehyde-3-phosphate dehydrogenase mRNA levels in isolated rabbit aorta. 1996 Am. J. Physiol. pmid:8769737
Plishker GA et al. Involvement of a cytoplasmic protein in calcium-dependent potassium efflux in red blood cells. 1986 Am. J. Physiol. pmid:3532815
Wu Y et al. Alterations in reactive oxygen, pH, and calcium in astrocytoma cells during lethal injury. 1996 Am. J. Physiol. pmid:8772436
Matsumoto Y et al. Creatine kinase kinetics in diabetic cardiomyopathy. 1995 Am. J. Physiol. pmid:7611380
Fiddian-Green RG and Silen W Mechanisms of disposal of acid and alkali in rabbit duodenum. 1975 Am. J. Physiol. pmid:2019
Gores GJ et al. Swelling, reductive stress, and cell death during chemical hypoxia in hepatocytes. 1989 Am. J. Physiol. pmid:2764095
Chih CP et al. Energy metabolism, ion homeostasis, and evoked potentials in anoxic turtle brain. 1989 Am. J. Physiol. pmid:2802002
Griendling KK et al. Pregnancy-induced changes in sheep uterine and carotid arteries. 1985 Am. J. Physiol. pmid:2581458
Ramp WK and Demaree DN Inhibition of net calcium efflux from bone by ethanol in vitro. 1984 Am. J. Physiol. pmid:6696057
Wendt IR and Chapman JB Fluorometric studies of recovery metabolism of rat fast- and slow-twitch muscles. 1976 Am. J. Physiol. pmid:937554
Wendt IR and Gibbs CL Recovery heat production of mammalian fast- and slow-twitch muscles. 1976 Am. J. Physiol. pmid:937562
Alvarado RH et al. Chloride transport across isolated skin of Rana pipiens. 1975 Am. J. Physiol. pmid:1082245
Bagnasco S et al. Lactate production in isolated segments of the rat nephron. 1985 Am. J. Physiol. pmid:3985159
Plishker GA Iodoacetic acid inhibition of calcium-dependent potassium efflux in red blood cells. 1985 Am. J. Physiol. pmid:3993768
Post JA et al. pHe, [Ca2+]e, and cell death during metabolic inhibition: role of phospholipase A2 and sarcolemmal phospholipids. 1998 Am. J. Physiol. pmid:9458847
Herchuelz A and Malaisse WJ Regulation of calcium fluxes in pancreatic islets: two calcium movements' dissociated response to glucose. 1980 Am. J. Physiol. pmid:6767412
Sick TJ et al. Brain potassium ion homeostasis, anoxia, and metabolic inhibition in turtles and rats. 1982 Am. J. Physiol. pmid:6287869
SANDOW A and KARCZMAR AG Effect of iodoacetate on changes in muscular latency induced by activity. 1950 Am. J. Physiol. pmid:14789991
Shryock JC et al. Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. 1988 Am. J. Physiol. pmid:3344813
Yokozeki H et al. Partial purification and characterization of cysteine proteinases in eccrine sweat. 1987 Am. J. Physiol. pmid:3109264
Steinberg H et al. Depression of pulmonary 5-hydroxytryptamine uptake by metabolic inhibitors. 1975 Am. J. Physiol. pmid:1130533
Stokes JB et al. Purification of rat papillary collecting duct cells: functional and metabolic assessment. 1987 Am. J. Physiol. pmid:3303974
Norris SH and Hersey SJ Stimulation of pepsinogen secretion in permeable isolated gastric glands. 1985 Am. J. Physiol. pmid:3876033
Johnson V and Maack T Renal extraction, filtration, absorption, and catabolism of growth hormone. 1977 Am. J. Physiol. pmid:910912
Said HM and Redha R A carrier-mediated system for transport of biotin in rat intestine in vitro. 1987 Am. J. Physiol. pmid:3812688
Apstein CS et al. Acute cardiac ischemia and reperfusion: contractility, relaxation, and glycolysis. 1978 Am. J. Physiol. pmid:736151
Sahlin K et al. Effects of lactic acid accumulation and ATP decrease on muscle tension and relaxation. 1981 Am. J. Physiol. pmid:7212053
Kone BC et al. Cellular pathways of potassium transport in renal inner medullary collecting duct. 1989 Am. J. Physiol. pmid:2539729
Sayeed MM Alterations in cellular Ca2+ regulation in the liver in endotoxic shock. 1986 Am. J. Physiol. pmid:3706573
Rodríguez-Estrada C Reduced nicotinamide adenine dinucleotide and depolarization in neurons. 1975 Am. J. Physiol. pmid:165729
Fang HK et al. Cardiac contractile function during coronary stenosis in dogs: association of adenosine in glycolytic dependence. 1997 Am. J. Physiol. pmid:9176286
Koss KL and Grubbs RD Elevated extracellular Mg2+ increases Mg2+ buffering through a Ca-dependent mechanism in cardiomyocytes. 1994 Am. J. Physiol. pmid:8074196
Gramolini A and Renaud JM Blocking ATP-sensitive K+ channel during metabolic inhibition impairs muscle contractility. 1997 Am. J. Physiol. pmid:9227423
Xie LH et al. Development of inwardly rectifying K+ channel family in rat ventricular myocytes. 1997 Am. J. Physiol. pmid:9139958
Dobrin P and Canfield T Identification of smooth muscle series elastic component in intact carotid artery. 1977 Am. J. Physiol. pmid:190898
Lorenz JN and Paul RJ Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. 1997 Am. J. Physiol. pmid:9124463
Hurwitz A Drug uptake into everted intestinal sacs. II. Inhibition of secretion by hypertonicity. 1979 Am. J. Physiol. pmid:35006
Selvaggio AM et al. Mechanisms of H+ secretion by inner medullary collecting duct cells. 1988 Am. J. Physiol. pmid:3348416
Hansen SP and Gesser H Extracellular Ca2+, force, and energy state in cardiac tissue of rainbow trout. 1987 Am. J. Physiol. pmid:3425763
Nakamura K et al. Glycolysis is necessary to preserve myocardial Ca2+ homeostasis during beta-adrenergic stimulation. 1993 Am. J. Physiol. pmid:8384419
Ahearn GA Intestinal electrophysiology and transmural ion transport in freshwater prawns. 1980 Am. J. Physiol. pmid:7395980