| MeSH term | MeSH ID | Detail |
|---|---|---|
| Leukemia, Erythroblastic, Acute | D004915 | 41 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Glycogen Storage Disease | D006008 | 4 associated lipids |
| Hemolysis | D006461 | 131 associated lipids |
| Carcinoma, Hepatocellular | D006528 | 140 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Hypocalcemia | D006996 | 12 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Machalińska A et al. | Sodium iodate selectively injuries the posterior pole of the retina in a dose-dependent manner: morphological and electrophysiological study. | 2010 | Neurochem. Res. | pmid:20725778 |
| Kelleher JA et al. | Energy metabolism in hypoxic astrocytes: protective mechanism of fructose-1,6-bisphosphate. | 1995 | Neurochem. Res. | pmid:7477671 |
| Lu GW et al. | Alteration of oxygen consumption and energy metabolism during repetitive exposure of mice to hypoxia. | 1999 | Neurochem. Res. | pmid:10344590 |
| Santos MS et al. | Stimulation of immunoreactive insulin release by glucose in rat brain synaptosomes. | 1999 | Neurochem. Res. | pmid:9973234 |
| Criado M et al. | Sulphydryl groups and iodo-[3H]acetic acid labeling in proteolipids from Torpedo electroplax. | 1983 | Neurochem. Res. | pmid:6888654 |
| Chakrabarti AK and Banik NL | Purification of calcium-activated neutral proteinase (CANP) from purified myelin of bovine brain white matter. | 1988 | Neurochem. Res. | pmid:2834658 |
| Ray P et al. | Cyanide sensitive and insensitive bioenergetics in a clonal neuroblastoma x glioma hybrid cell line. | 1991 | Neurochem. Res. | pmid:1795758 |
| Bender AS et al. | The rapid L- and D-aspartate uptake in cultured astrocytes. | 1997 | Neurochem. Res. | pmid:9178956 |
| MejÃa-Toiber J et al. | D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo. | 2006 | Neurochem. Res. | pmid:17115265 |
| Aratan-Spire S et al. | Enzymatic degradation of thyrotropin releasing hormone by pancreatic homogenates. Failure to detect His-Pro-diketopiperazine as TRH metabolite. | 1986 | Neuroendocrinology | pmid:3084986 |
| Ferland CE et al. | Determination of specific neuropeptides modulation time course in a rat model of osteoarthritis pain by liquid chromatography ion trap mass spectrometry. | 2011 | Neuropeptides | pmid:21855139 |
| Kobayashi H et al. | Effects of arsenic on cholinergic parameters in brain in vitro. | 1987 | Neuropharmacology | pmid:3437937 |
| Widmer J et al. | Exchange mechanism of tyrosine between plasma and red blood cells in normal subjects and psychiatric patients. | 1982 | Neuropsychobiology | pmid:7133368 |
| Balijepalli S et al. | Effect of thiol modification on brain mitochondrial complex I activity. | 1999 | Neurosci. Lett. | pmid:10505616 |
| Chaplain RA | Intracellular recordings from granule cells in the rabbit bulbus olfactorius. | 1976 | Neurosci. Lett. | pmid:19604875 |
| Reiner PB et al. | A pharmacological model of ischemia in the hippocampal slice. | 1990 | Neurosci. Lett. | pmid:2280893 |
| Rogel A et al. | Phospholipase C is involved in the adenosine-activated signal transduction pathway conferring protection against iodoacetic acid-induced injury in primary rat neuronal cultures. | 2005 | Neurosci. Lett. | pmid:15619546 |
| Izumi Y et al. | Monocarboxylates (pyruvate and lactate) as alternative energy substrates for the induction of long-term potentiation in rat hippocampal slices. | 1997 | Neurosci. Lett. | pmid:9292881 |
| Liu P et al. | Ongoing pain in the MIA model of osteoarthritis. | 2011 | Neurosci. Lett. | pmid:21241772 |
| Yoshioka K et al. | Characteristics of monocarboxylates as energy substrates other than glucose in rat brain slices and the effect of selective glial poisoning - a 31P NMR study. | 2000 | Neurosci. Res. | pmid:10683525 |
| Lapchak PA et al. | Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes. | 2007 | Neuroscience | pmid:17942241 |
| Gibbs ME et al. | Astrocytic energy metabolism consolidates memory in young chicks. | 2006 | Neuroscience | pmid:16750889 |
| Massieu L et al. | Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition. | 2003 | Neuroscience | pmid:12890508 |
| Kauppinen RA et al. | Ca2+-dependent and Ca2+-independent glutamate release, energy status and cytosolic free Ca2+ concentration in isolated nerve terminals following metabolic inhibition: possible relevance to hypoglycaemia and anoxia. | 1988 | Neuroscience | pmid:2904664 |
| Locklear I et al. | Metabolic myopathy produced by acute inhibition of glyceraldehyde-3-phosphate dehydrogenase with ortho-iodosobenzoic acid. | 1990 | Neuroscience | pmid:2381520 |
| Camacho A et al. | The anion channel blocker, 4,4'-dinitrostilbene-2,2'-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo. | 2006 | Neuroscience | pmid:16920271 |
| Gemba T et al. | Glutamate efflux via the reversal of the sodium-dependent glutamate transporter caused by glycolytic inhibition in rat cultured astrocytes. | 1994 | Neuroscience | pmid:7898678 |
| Rahman W et al. | Electrophysiological evidence for voltage-gated calcium channel 2 (Cav2) modulation of mechano- and thermosensitive spinal neuronal responses in a rat model of osteoarthritis. | 2015 | Neuroscience | pmid:26247695 |
| Uruno T et al. | Determination of Ca2+-release from the isolated smooth muscle cells in suspension from the guinea-pig ileum. | 1987 | Nihon Heikatsukin Gakkai Zasshi | pmid:3444154 |
| Wakabayashi S et al. | [The effect of glucose concentrations on the functional maturation of monolayer-cultured B cells of neonatal rat pancreases]. | 1986 | Nihon Naibunpi Gakkai Zasshi | pmid:3542593 |
| Wakabayashi S et al. | [Perifusion of monolayer-cultured B cells of the infant rat: a comparative study of the effects of 2-deoxy-2-fluoroglucose and iodoacetic acid]. | 1988 | Nihon Naibunpi Gakkai Zasshi | pmid:3294052 |
| Nakano K et al. | [Studies on the relationship between the oxygen uptake and the release of amylase and sialic acid]. | 1985 | Nihon Seirigaku Zasshi | pmid:2418200 |
| Totsuka H and Kuwabara T | [Histopathological study of experimental cataract induced by intravitreal injection of iodoacetic acid]. | 1988 | Nippon Ganka Gakkai Zasshi | pmid:3189052 |
| Tamai A et al. | [ERP of experimental retinitis pigmentosa--effects of intravenous injection of monoiodoacetic acid on the pigmented rabbit ERP (author's transl)]. | 1973 | Nippon Ganka Gakkai Zasshi | pmid:4799593 |
| Nasu K | [Choroidal blood flow in chronic stage of selective retinal damage after monoiodoacetic acid injection]. | 1990 | Nippon Ganka Gakkai Zasshi | pmid:2368642 |
| Suzuki R et al. | [Divalent chelating agents, calcium blockers and metabolic inhibitors had different effects on the iris sphincter muscles]. | 1986 | Nippon Ganka Gakkai Zasshi | pmid:3716941 |
| Kobayashi T et al. | [Effects of iodoacetic acid upon cochlear potentials and the mechanism of CM2 production]. | 1983 | Nippon Jibiinkoka Gakkai Kaiho | pmid:6631583 |
| Tomioka H et al. | [The difference of drug sensitivity of tumor cells on N-ethyloxycarbonylaminomethyl-L-isoleucine (A-145 (author's transl)]. | 1979 | Nippon Yakurigaku Zasshi | pmid:437584 |
| Furukawa N et al. | [A biochemical study of an animal model with defective muscle glycolysis, induced by iodoacetate administration]. | 1992 | No To Hattatsu | pmid:1520510 |
| Rogel A et al. | The neuroprotective adenosine-activated signal transduction pathway involves activation of phospholipase C. | 2006 | Nucleosides Nucleotides Nucleic Acids | pmid:17065107 |
| Gallis JL et al. | A metabolic link between mitochondrial ATP synthesis and liver glycogen metabolism: NMR study in rats re-fed with butyrate and/or glucose. | 2011 | Nutr Metab (Lond) | pmid:21676253 |
| Reyes-FermÃn LM et al. | Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death. | 2012 | Nutr Neurosci | pmid:22776704 |
| Knock FE et al. | Effects of selected sulfhydryl inhibitors on nonhistone chromosomal proteins of HeLa cells. | 1975 | Oncology | pmid:1228540 |
| Sarigianni M et al. | Involvement of signaling molecules on na/h exchanger-1 activity in human monocytes. | 2010 | Open Cardiovasc Med J | pmid:21160910 |
| Shen Y et al. | Effect of Guanabenz on Rat AMD Models and Rabbit Choroidal Blood Flow. | 2011 | Open Ophthalmol J | pmid:21633720 |
| Ono S and Hirano H | Riboflavin metabolism in the single lens of rat. | 1983 | Ophthalmic Res. | pmid:6634050 |
| Delamere NA and Paterson CA | Studies on calcium regulation in relation to sodium-potassium balance in the rabbit lens. | 1982 | Ophthalmic Res. | pmid:7099540 |
| Ponte F et al. | Iodoacetic acid influence on the aerobic glycolysis in surviving retinae of normal rats and of carriers of inherited retinal degeneration. | 1974 | Ophthalmologica | pmid:4852565 |
| Ono M et al. | Purification and characterization of a thiol-protease from Bacteroides gingivalis strain 381. | 1987 | Oral Microbiol. Immunol. | pmid:10870472 |
| Boudenot A et al. | Effect of interval-training exercise on subchondral bone in a chemically-induced osteoarthritis model. | 2014 | Osteoarthr. Cartil. | pmid:24928318 |