Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Leukemia, Experimental D007942 42 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lymphoma D008223 18 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Muscle Cramp D009120 3 associated lipids
Nerve Degeneration D009410 53 associated lipids
Osteoarthritis D010003 4 associated lipids
Pain D010146 64 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Retinitis D012173 4 associated lipids
Rickets D012279 6 associated lipids
Rigor Mortis D012298 1 associated lipids
Sarcoma 180 D012510 21 associated lipids
Starvation D013217 47 associated lipids
Temporomandibular Joint Disorders D013705 4 associated lipids
Theileriasis D013801 7 associated lipids
Thrombocytopenia D013921 15 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Yamauchi Y et al. Correlation between high-resolution optical coherence tomography (OCT) images and histopathology in an iodoacetic acid-induced model of retinal degeneration in rabbits. 2011 Br J Ophthalmol pmid:21030415
Yang R et al. Partial purification and characterisation of cysteine protease in wheat germ. 2011 J. Sci. Food Agric. pmid:21702054
Orita S et al. Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain. 2011 BMC Musculoskelet Disord pmid:21679434
Nam J et al. Transcriptome-wide gene regulation by gentle treadmill walking during the progression of monoiodoacetate-induced arthritis. 2011 Arthritis Rheum. pmid:21400474
Siebelt M et al. Quantifying osteoarthritic cartilage changes accurately using in vivo microCT arthrography in three etiologically distinct rat models. 2011 J. Orthop. Res. pmid:21520262
Huang J et al. Isolation, characterization and identification of a Paracoccus sp. 2-haloacid-degrading bacterium from the marine sponge Hymeniacidon perlevis. 2011 J. Basic Microbiol. pmid:21298680
Schuelert N et al. Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis. 2011 Pain pmid:21185649
Scott PA et al. Anatomical evidence of photoreceptor degeneration induced by iodoacetic acid in the porcine eye. 2011 Exp. Eye Res. pmid:21740901
Ataman OV and Ataman IuO [Comparative characteristic of energy supply disturbances in arterial and venous walls of rabbits with alloxan diabetes and monoiodacetate intoxication]. 2011 Fiziol Zh pmid:21848224
Wang W et al. Selective rod degeneration and partial cone inactivation characterize an iodoacetic acid model of Swine retinal degeneration. 2011 Invest. Ophthalmol. Vis. Sci. pmid:21896868
Nam J et al. Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis. 2011 PLoS ONE pmid:21931681
Buchwalow I et al. Non-specific binding of antibodies in immunohistochemistry: fallacies and facts. 2011 Sci Rep pmid:22355547
Kim JS et al. Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis. 2011 Arthritis Rheum. pmid:21953085
Andres Ibarra R et al. Disturbances in the glutathione/ophthalmate redox buffer system in the woodchuck model of hepatitis virus-induced hepatocellular carcinoma. 2011 HPB Surg pmid:21941408
Hettling H and van Beek JH Analyzing the functional properties of the creatine kinase system with multiscale 'sloppy' modeling. 2011 PLoS Comput. Biol. pmid:21912519
Bezawada J et al. Recovery of Bacillus licheniformis Alkaline Protease from Supernatant of Fermented Wastewater Sludge Using Ultrafiltration and Its Characterization. 2011 Biotechnol Res Int pmid:21876816
Cherel P et al. Joint analysis of quantitative trait loci and major-effect causative mutations affecting meat quality and carcass composition traits in pigs. 2011 BMC Genet. pmid:21875434
Rawlings ND et al. Asparagine peptide lyases: a seventh catalytic type of proteolytic enzymes. 2011 J. Biol. Chem. pmid:21832066
House SA et al. Giardia flagellar motility is not directly required to maintain attachment to surfaces. 2011 PLoS Pathog. pmid:21829364
Yu J et al. Mussel protein adhesion depends on interprotein thiol-mediated redox modulation. 2011 Nat. Chem. Biol. pmid:21804534
Li A et al. Serotonin Receptor 2A/C Is Involved in Electroacupuncture Inhibition of Pain in an Osteoarthritis Rat Model. 2011 Evid Based Complement Alternat Med pmid:21799685
Woo YJ et al. Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis. 2011 Exp. Mol. Med. pmid:21795829
Abbas R et al. The dynamics of glutathione species and ophthalmate concentrations in plasma from the VX2 rabbit model of secondary liver tumors. 2011 HPB Surg pmid:21350723
Kovacic PB et al. New insights into cytosolic glucose levels during differentiation of 3T3-L1 fibroblasts into adipocytes. 2011 J. Biol. Chem. pmid:21349852
Ulanovskaya OA et al. A pairwise chemical genetic screen identifies new inhibitors of glucose transport. 2011 Chem. Biol. pmid:21338919
Liao HH et al. Down-regulation of granulocyte-macrophage colony-stimulating factor by 3C-like proteinase in transfected A549 human lung carcinoma cells. 2011 BMC Immunol. pmid:21324206
Porteus C et al. Time domains of the hypoxic ventilatory response in ectothermic vertebrates. 2011 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:21312038
Sánchez-Aragó M and Cuezva JM The bioenergetic signature of isogenic colon cancer cells predicts the cell death response to treatment with 3-bromopyruvate, iodoacetate or 5-fluorouracil. 2011 J Transl Med pmid:21303518
Singla DK et al. TGF-β2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21297031
Jufvas A et al. Histone variants and their post-translational modifications in primary human fat cells. 2011 PLoS ONE pmid:21249133
Samgina TY et al. Novel cysteine tags for the sequencing of non-tryptic disulfide peptides of anurans: ESI-MS study of fragmentation efficiency. 2011 J. Am. Soc. Mass Spectrom. pmid:21979873
Al-Jallad HF et al. Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics. 2011 PLoS ONE pmid:21283799
Wang YC et al. Intracellular Na(+) and metabolic modulation of Na/K pump and excitability in the rat suprachiasmatic nucleus neurons. 2012 J. Neurophysiol. pmid:22773774
Wang XD et al. Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate. 2012 PLoS ONE pmid:22984604
Lee JH et al. Alteration patterns of trabecular bone microarchitectural characteristics induced by osteoarthritis over time. 2012 Clin Interv Aging pmid:22956865
Moon SJ et al. Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes. 2012 Osteoarthr. Cartil. pmid:22890185
Downs I et al. The ROS scavenger, NAC, regulates hepatic Vα14iNKT cells signaling during Fas mAb-dependent fulminant liver failure. 2012 PLoS ONE pmid:22701598
Sotelo-Hitschfeld T et al. Acute feedback control of astrocytic glycolysis by lactate. 2012 Glia pmid:22290492
Lunetta C et al. Impaired expression of insulin-like growth factor-1 system in skeletal muscle of amyotrophic lateral sclerosis patients. 2012 Muscle Nerve pmid:22246875
Xie L et al. Quantitative imaging of cartilage and bone morphology, reactive oxygen species, and vascularization in a rodent model of osteoarthritis. 2012 Arthritis Rheum. pmid:22231023
Izumi M et al. RBCS1A and RBCS3B, two major members within the Arabidopsis RBCS multigene family, function to yield sufficient Rubisco content for leaf photosynthetic capacity. 2012 J. Exp. Bot. pmid:22223809
Fiaschi T et al. Redox Regulation of Nonmuscle Myosin Heavy Chain during Integrin Engagement. 2012 J Signal Transduct pmid:22220276
Vincent A et al. parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress. 2012 Hum. Mol. Genet. pmid:22215442
North SJ et al. Glycomic analysis of human mast cells, eosinophils and basophils. 2012 Glycobiology pmid:21725073
Shimada T et al. Development of iodoacetic acid-based cysteine mass tags: detection enhancement for cysteine-containing peptide by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. 2012 Anal. Biochem. pmid:22206935
Reyes-Fermín LM et al. Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death. 2012 Nutr Neurosci pmid:22776704
Ferreira-Gomes J et al. Dose-dependent expression of neuronal injury markers during experimental osteoarthritis induced by monoiodoacetate in the rat. 2012 Mol Pain pmid:22769424
Noel JM et al. Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage. 2012 Exp. Eye Res. pmid:22251455
Hardes K et al. Design, synthesis, and characterization of chromogenic substrates of coagulation factor XIIIa. 2012 Anal. Biochem. pmid:22683584
Rao Y et al. Mapping of sulfur metabolic pathway by LC Orbitrap mass spectrometry. 2012 Anal. Chim. Acta pmid:22405311