Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Rickets D012279 6 associated lipids
Retinitis D012173 4 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Pain D010146 64 associated lipids
Osteoarthritis D010003 4 associated lipids
Nerve Degeneration D009410 53 associated lipids
Muscle Cramp D009120 3 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Lymphoma D008223 18 associated lipids
Lung Neoplasms D008175 171 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Inflammation D007249 119 associated lipids
Hypocalcemia D006996 12 associated lipids
Hyperlipidemias D006949 73 associated lipids
Hyperalgesia D006930 42 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Dadlez M and Kim PS Rapid formation of the native 14-38 disulfide bond in the early stages of BPTI folding. 1996 Biochemistry pmid:8973187
Dux E et al. Early ultrastructural changes after brief histotoxic hypoxia in cultured cortical and hippocampal CA1 neurons. 1996 Acta Neuropathol. pmid:8960310
Guzzo A et al. Analysis of the region between amino acids 30 and 42 of intact UmuD by a monocysteine approach. 1996 J. Bacteriol. pmid:8955415
Tozawa K et al. Unusual pKa of the carboxylate at the putative catalytic position of the thermophilic F1-ATPase beta subunit determined by 13C-NMR. 1996 FEBS Lett. pmid:8941727
Leif RC et al. A procedure for dissociating Ayre scrape samples. 1977 J. Histochem. Cytochem. pmid:894001
Wells JE and Russell JB The effect of growth and starvation on the lysis of the ruminal cellulolytic bacterium Fibrobacter succinogenes. 1996 Appl. Environ. Microbiol. pmid:8919795
Saransaari P and Oja SS Taurine and neural cell damage. Transport of taurine in adult and developing mice. 1996 Adv. Exp. Med. Biol. pmid:8915386
Malek A et al. Energy charge monitoring via magnetic resonance spectroscopy 31P in the perfused human placenta: effects of cadmium, dinitrophenol and iodoacetate. 1996 Placenta pmid:8899879
Hartmund T and Gesser H Cardiac force and high-energy phosphates under metabolic inhibition in four ectothermic vertebrates. 1996 Am. J. Physiol. pmid:8897986
Tabillion R and Kaltwasser H [Energy-dependent 63Ni-uptake by Alcaligenes eutrophus strains H1 and H16 (author's transl)]. 1977 Arch. Microbiol. pmid:889383
Webster DR and Oxford MG Regulation of cytoplasmic tubulin carboxypeptidase activity in vitro by cations and sulfhydryl-modifying compounds. 1996 J. Cell. Biochem. pmid:8867817
Zhang ZY et al. Catalytic function of the conserved hydroxyl group in the protein tyrosine phosphatase signature motif. 1995 Biochemistry pmid:8845365
Kelly MJ and Richardson W Possible mechanisms for the protective action of alpha-tocopherol in vascular hypoxia. 1996 J Auton Pharmacol pmid:8842869
Mackert BM et al. Anoxia in vitro does not induce neuronal swelling or death. 1996 J. Neurol. Sci. pmid:8836970
Xu M and Akabas MH Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit. 1996 J. Gen. Physiol. pmid:8833341
Chew A et al. Mutations in a putative zinc-binding domain inactivate the mitochondrial intermediate peptidase. 1996 Biochem. Biophys. Res. Commun. pmid:8831696
Collinson IR et al. The F1F0-ATPase complex from bovine heart mitochondria: the molar ratio of the subunits in the stalk region linking the F1 and F0 domains. 1996 Biochemistry pmid:8823202
Godeas C et al. Rat testis mitochondrial phospholipid hydroperoxide glutathione peroxidase does not protect endogenous vitamin E against Fe2+-induced (lipo)peroxidation. 1996 Biochem. Mol. Med. pmid:8812743
Wu Y et al. Changes in membrane properties during energy depletion-induced cell injury studied with fluorescence microscopy. 1996 Biophys. J. pmid:8804592
Han Z et al. DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease. 1996 J. Biol. Chem. pmid:8798786