Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Stroke D020521 32 associated lipids
Starvation D013217 47 associated lipids
Hypocalcemia D006996 12 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Nerve Degeneration D009410 53 associated lipids
Leukemia, Experimental D007942 42 associated lipids
Hyperalgesia D006930 42 associated lipids
Thrombocytopenia D013921 15 associated lipids
Hyperlipidemias D006949 73 associated lipids
Rickets D012279 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Byssinosis D002095 11 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Blindness D001766 6 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Calmettes G et al. Improved energy supply regulation in chronic hypoxic mouse counteracts hypoxia-induced altered cardiac energetics. 2010 PLoS ONE pmid:20174637
Edes K et al. JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1. 2010 PLoS ONE pmid:20098717
Castillo-Romero A et al. Participation of actin on Giardia lamblia growth and encystation. 2009 PLoS ONE pmid:19774081
Charles RC et al. Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium. 2009 PLoS ONE pmid:19746165
Ahamed J et al. In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1. 2009 PLoS ONE pmid:19672301
Wei Y et al. Binding to the minor groove of the double-strand, tau protein prevents DNA from damage by peroxidation. 2008 PLoS ONE pmid:18596978
Goytia M et al. Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens. 2007 PLoS ONE pmid:17849014
Wang XD et al. Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate. 2012 PLoS ONE pmid:22984604
Downs I et al. The ROS scavenger, NAC, regulates hepatic Vα14iNKT cells signaling during Fas mAb-dependent fulminant liver failure. 2012 PLoS ONE pmid:22701598
Du J et al. The protein partners of GTP cyclohydrolase I in rat organs. 2012 PLoS ONE pmid:22479495
Thakur M et al. Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis. 2012 PLoS ONE pmid:22470467
Sun L et al. N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity. 2012 PLoS ONE pmid:22442667
Lee M et al. Direct sensing of endothelial oxidants by vascular endothelial growth factor receptor-2 and c-Src. 2011 PLoS ONE pmid:22145046
Sabari J et al. Fibronectin matrix assembly suppresses dispersal of glioblastoma cells. 2011 PLoS ONE pmid:21980357
Jeong YJ et al. Anti-Osteoarthritic Effects of the Litsea japonica Fruit in a Rat Model of Osteoarthritis Induced by Monosodium Iodoacetate. 2015 PLoS ONE pmid:26244981
Kodali VK et al. A novel disulfide-rich protein motif from avian eggshell membranes. 2011 PLoS ONE pmid:21479176
Zilliges Y et al. The cyanobacterial hepatotoxin microcystin binds to proteins and increases the fitness of microcystis under oxidative stress conditions. 2011 PLoS ONE pmid:21445264
John S et al. Subcellular localization of hexokinases I and II directs the metabolic fate of glucose. 2011 PLoS ONE pmid:21408025
Wang Q et al. Purification and characterization of a CkTLP protein from Cynanchum komarovii seeds that confers antifungal activity. 2011 PLoS ONE pmid:21364945
Liu X et al. An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water. 2013 PLoS ONE pmid:23613747