| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stroke | D020521 | 32 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Hypocalcemia | D006996 | 12 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Thrombocytopenia | D013921 | 15 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Rickets | D012279 | 6 associated lipids |
| Blood Platelet Disorders | D001791 | 12 associated lipids |
| Byssinosis | D002095 | 11 associated lipids |
| Pre-Eclampsia | D011225 | 16 associated lipids |
| Vitamin D Deficiency | D014808 | 13 associated lipids |
| Vascular Diseases | D014652 | 16 associated lipids |
| Photosensitivity Disorders | D010787 | 8 associated lipids |
| Thymus Neoplasms | D013953 | 15 associated lipids |
| Blindness | D001766 | 6 associated lipids |
| Vitamin B 6 Deficiency | D026681 | 10 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ohta A et al. | Effect of lipid peroxidation on membrane-bound Ca2+-ATPase activity of the intestinal brush-border membranes. | 1989 | Biochim. Biophys. Acta | pmid:2527563 |
| Maublant JC et al. | Uptake and release of two new Tc-99m labeled myocardial blood flow imaging agents in cultured cardiac cells. | 1989 | Eur J Nucl Med | pmid:2753050 |
| Gores GJ et al. | Swelling, reductive stress, and cell death during chemical hypoxia in hepatocytes. | 1989 | Am. J. Physiol. | pmid:2764095 |
| Lange K et al. | Endogenous regulation of 2-deoxyglucose uptake in C6 glioma cells correlates with cytoskeleton-mediated changes of surface morphology. | 1989 | J. Cell. Physiol. | pmid:2738110 |
| Vinnikov AI and Babenko IuS | [Features of glycolysis and pentose phosphate pathway in novobiocin sensitive and novobiocin resistant staphylococci]. | 1989 | Antibiot. Khimioter. | pmid:2730211 |
| Jennings RB et al. | Total ischemia III: Effect of inhibition of anaerobic glycolysis. | 1989 | J. Mol. Cell. Cardiol. | pmid:2733029 |
| Schlöffel G and Linss W | [The characterization of phagocytotic processes using morphometry]. | 1989 | Gegenbaurs Morphol Jahrb | pmid:2737410 |
| Huang YC and Colman RF | Aspartyl peptide labeled by 2-(4-bromo-2,3-dioxobutylthio)adenosine 5'-diphosphate in the allosteric ADP site of pig heart NAD+-dependent isocitrate dehydrogenase. | 1989 | J. Biol. Chem. | pmid:2745437 |
| Chih CP et al. | Energy metabolism, ion homeostasis, and evoked potentials in anoxic turtle brain. | 1989 | Am. J. Physiol. | pmid:2802002 |
| Bernström K et al. | Metabolism of leukotriene E4 to 5-hydroxy-6-mercapto7,9-trans-11,14-cis-eicosatetraenoic acid by microfloral cysteine-conjugate beta-lyase and rat cecum contents. | 1989 | Arch. Biochem. Biophys. | pmid:2556967 |
| Camici G et al. | The complete amino acid sequence of the low molecular weight cytosolic acid phosphatase. | 1989 | J. Biol. Chem. | pmid:2644264 |
| Liao TH et al. | Deoxyribonuclease II purified from the isolated lysosomes of porcine spleen and from porcine liver homogenates. Comparison with deoxyribonuclease II purified from porcine spleen homogenates. | 1989 | Biochim. Biophys. Acta | pmid:2909240 |
| Nicotera P et al. | Cytosolic-free Ca2+ and cell killing in hepatoma 1c1c7 cells exposed to chemical anoxia. | 1989 | FASEB J. | pmid:2910738 |
| Barron JT et al. | Effects of ATP reduction on the pattern of force development and myosin light chain phosphorylation in intact arterial smooth muscle. | 1989 | Biochim. Biophys. Acta | pmid:2912507 |
| Rasio EA et al. | Effect of reduced energy metabolism and reperfusion on the permeability and morphology of the capillaries of an isolated rete mirabile. | 1989 | Circ. Res. | pmid:2912596 |
| Tomlinson G and Kinsch EM | S-mercuric-N-dansyl-cysteine labels the free sulfhydryl groups of human serum cholinesterase. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2916998 |
| Goswami A and Rosenberg IN | Reactive thiols in type II iodothyronine 5'-deiodinases: inactivation by iodoacetate. | 1989 | Biochem. Int. | pmid:2818601 |
| Beinfeld MC et al. | Characterization of an endoprotease from rat small intestinal mucosal secretory granules which generates somatostatin-28 from prosomatostatin by cleavage after a single arginine residue. | 1989 | J. Biol. Chem. | pmid:2564394 |
| Nakanishi Y et al. | Sulfhydryl groups of an extramitochondrial acetyl-CoA hydrolase from rat liver. | 1989 | Biochim. Biophys. Acta | pmid:2568854 |
| Iwamoto K et al. | Effects of metabolic inhibitors and incubation temperature on the saturable uptake of propranolol by isolated rat lung tissue. | 1989 | J. Pharm. Pharmacol. | pmid:2571706 |
| Kyprianou N and Isaacs JT | "Thymineless" death in androgen-independent prostatic cancer cells. | 1989 | Biochem. Biophys. Res. Commun. | pmid:2531584 |
| Tyson PA et al. | Identification of the 5-iodoacetamidofluorescein reporter site on the Na,K-ATPase. | 1989 | J. Biol. Chem. | pmid:2536022 |
| Gores GJ et al. | Intracellular pH during "chemical hypoxia" in cultured rat hepatocytes. Protection by intracellular acidosis against the onset of cell death. | 1989 | J. Clin. Invest. | pmid:2536397 |
| Kone BC et al. | Cellular pathways of potassium transport in renal inner medullary collecting duct. | 1989 | Am. J. Physiol. | pmid:2539729 |
| Lu HS et al. | Human urinary kallikrein. Complete amino acid sequence and sites of glycosylation. | 1989 | Int. J. Pept. Protein Res. | pmid:2666327 |
| Trageser M and Unden G | Role of cysteine residues and of metal ions in the regulatory functioning of FNR, the transcriptional regulator of anaerobic respiration in Escherichia coli. | 1989 | Mol. Microbiol. | pmid:2668693 |
| Menashi S et al. | Interaction of platelets with endothelial cells: activation of a novel neutral protease. | 1989 | Exp. Cell Res. | pmid:2670593 |
| Tisljar U and Barrett AJ | Purification and characterization of Pz-peptidase from rabbit muscle. | 1989 | Arch. Biochem. Biophys. | pmid:2673041 |
| Slaby I and Holmgren A | Thioredoxin reductase-dependent insulin disulfide reduction by phage T7 DNA polymerase reflects dissociation of the enzyme into subunits. | 1989 | J. Biol. Chem. | pmid:2674134 |
| Atkinson MM and Baker CJ | Role of the Plasmalemma H-ATPase in Pseudomonas syringae-Induced K/H Exchange in Suspension-Cultured Tobacco Cells. | 1989 | Plant Physiol. | pmid:16667014 |
| Dennis PA et al. | Alpha 2-macroglobulin is a binding protein for basic fibroblast growth factor. | 1989 | J. Biol. Chem. | pmid:2468667 |
| Trotter GW et al. | Effects of intramuscular polysulfated glycosaminoglycan on chemical and physical defects in equine articular cartilage. | 1989 | Can. J. Vet. Res. | pmid:2469533 |
| Clogston CL et al. | Disulfide structures of human interleukin-6 are similar to those of human granulocyte colony stimulating factor. | 1989 | Arch. Biochem. Biophys. | pmid:2472117 |
| Eaton BM et al. | Uptake of alpha 2-macroglobulin-trypsin complex by human placenta is mediated by a microvillous membrane receptor. | 1989 | Cell Biochem. Funct. | pmid:2473854 |
| Kusen' SI et al. | [Insulin-degrading neutral proteinases of the plasma membrane of loach liver and embryo cells]. | 1989 Jan-Feb | Ukr. Biokhim. Zh. | pmid:2662544 |
| ten Kate RW et al. | Handling of human pepsinogens by the isolated rat kidney: evidence for a high glomerular sieving coefficient. | 1989 Jan-Feb | Ren. Physiol. Biochem. | pmid:2727383 |
| Williams JA and Thonar EJ | Early osteophyte formation after chemically induced articular cartilage injury. | 1989 Jan-Feb | Am J Sports Med | pmid:2929840 |
| Kokan-Moore NP and Bergdoll MS | Determination of biologically active region in toxic shock syndrome toxin 1. | 1989 Jan-Feb | Rev. Infect. Dis. | pmid:2467343 |
| Jean PA and Reed DJ | In vitro dipeptide, nucleoside, and glutathione alkylation by S-(2-chloroethyl)glutathione and S-(2-chloroethyl)-L-cysteine. | 1989 Nov-Dec | Chem. Res. Toxicol. | pmid:2519737 |
| Zakrzewska I et al. | Low molecular organic inactivators in differentiating organ origin of alpha-amylase in humans. Part I. | 1989 Oct-Dec | Mater Med Pol | pmid:2518736 |
| Mykkanen HM and Wasserman RH | Relationship of membrane-bound sulfhydryl groups to vitamin D-stimulated uptake of [75Se]Selenite by the brush border membrane vesicles from chick duodenum. | 1990 | J. Nutr. | pmid:2166146 |
| Jasra N et al. | Characterization of glucose uptake by Trichuris globulosa (Nematoda) in vitro. | 1990 | J. Helminthol. | pmid:2230035 |
| Zeevalk GD and Nicklas WJ | Chemically induced hypoglycemia and anoxia: relationship to glutamate receptor-mediated toxicity in retina. | 1990 | J. Pharmacol. Exp. Ther. | pmid:2162951 |
| Rao US and Scarborough GA | Chemical state of the cysteine residues in the Neurospora crassa plasma membrane H(+)-ATPase. | 1990 | J. Biol. Chem. | pmid:2139659 |
| Kuypers TW et al. | Continuous cell activation is necessary for stable interaction of complement receptor type 3 with its counter-structure in the aggregation response of human neutrophils. | 1990 | Eur. J. Immunol. | pmid:2180724 |
| Walker J et al. | Affinity chromatography of mammalian and yeast nucleosomes. Two modes of binding of transcriptionally active mammalian nucleosomes to organomercurial-agarose columns, and contrasting behavior of the active nucleosomes of yeast. | 1990 | J. Biol. Chem. | pmid:2180934 |
| Nasu T et al. | Iodoacetic acid-induced rigor in ileal longitudinal smooth muscle of guinea-pig. | 1990 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:1982870 |
| Takahashi N and Hirose M | Determination of sulfhydryl groups and disulfide bonds in a protein by polyacrylamide gel electrophoresis. | 1990 | Anal. Biochem. | pmid:2221388 |
| Elmore MJ et al. | Activation of potassium efflux from Escherichia coli by glutathione metabolites. | 1990 | Mol. Microbiol. | pmid:2192231 |
| Kleanthous C et al. | Active site labeling of the shikimate pathway enzyme, dehydroquinase. Evidence for a common substrate binding site within dehydroquinase and dehydroquinate synthase. | 1990 | J. Biol. Chem. | pmid:2193027 |
| Kleanthous C and Coggins JR | Reversible alkylation of an active site methionine residue in dehydroquinase. | 1990 | J. Biol. Chem. | pmid:2193028 |
| Buttle DJ et al. | The preparation of fully active chymopapain free of contaminating proteinases. | 1990 | Biol. Chem. Hoppe-Seyler | pmid:2085414 |
| Bode HP et al. | Vanadium uptake by yeast cells. | 1990 | Biochim. Biophys. Acta | pmid:2155019 |
| Saito T | Glucose-supported oxidative metabolism and evoked potentials are sensitive to fluoroacetate, an inhibitor of glial tricarboxylic acid cycle in the olfactory cortex slice. | 1990 | Brain Res. | pmid:2073603 |
| Kanaya S et al. | Role of cysteine residues in ribonuclease H from Escherichia coli. Site-directed mutagenesis and chemical modification. | 1990 | Biochem. J. | pmid:2171503 |
| Craig PA and Dekker EE | The sulfhydryl content of L-threonine dehydrogenase from Escherichia coli K-12: relation to catalytic activity and Mn2+ activation. | 1990 | Biochim. Biophys. Acta | pmid:2104757 |
| Miller RM et al. | Phosphorylase and creatine kinase modification by thiol-disulfide exchange and by xanthine oxidase-initiated S-thiolation. | 1990 | Arch. Biochem. Biophys. | pmid:2106288 |
| Jakes KS et al. | Alteration of the pH-dependent ion selectivity of the colicin E1 channel by site-directed mutagenesis. | 1990 | J. Biol. Chem. | pmid:1691183 |
| Nasu K | [Choroidal blood flow in chronic stage of selective retinal damage after monoiodoacetic acid injection]. | 1990 | Nippon Ganka Gakkai Zasshi | pmid:2368642 |
| Cánovas-Muñoz MD et al. | Amphiphilic and hydrophilic molecular forms of acetylcholinesterase in membranes derived from sarcoplasmic reticulum of skeletal muscle. | 1990 | Biochim. Biophys. Acta | pmid:2378890 |
| Locklear I et al. | Metabolic myopathy produced by acute inhibition of glyceraldehyde-3-phosphate dehydrogenase with ortho-iodosobenzoic acid. | 1990 | Neuroscience | pmid:2381520 |
| Mayer D et al. | Investigation by amperometric methods of intracellular reduction of 2,6-dichlorophenolindophenol in normal and transformed hepatocytes in the presence of different inhibitors of cellular metabolism. | 1990 | Biochim. Biophys. Acta | pmid:2297512 |
| Kawata Y et al. | Identification of two essential histidine residues of ribonuclease T2 from Aspergillus oryzae. | 1990 | Eur. J. Biochem. | pmid:2298207 |
| Kasuga N and Umazume Y | Deterioration induced by physiological concentration of calcium ions in skinned muscle fibres. | 1990 | J. Muscle Res. Cell. Motil. | pmid:2351746 |
| Piwnica-Worms D et al. | Effect of metabolic inhibition on technetium-99m-MIBI kinetics in cultured chick myocardial cells. | 1990 | J. Nucl. Med. | pmid:2324822 |
| Poon R and Hinberg I | One-step elimination of interference of free-sulfhydryl-containing drugs with Chemstrip ketone readings. | 1990 | Clin. Chem. | pmid:2387059 |
| Wray S | The effects of metabolic inhibition on uterine metabolism and intracellular pH in the rat. | 1990 | J. Physiol. (Lond.) | pmid:2388156 |
| Duchen MR | Effects of metabolic inhibition on the membrane properties of isolated mouse primary sensory neurones. | 1990 | J. Physiol. (Lond.) | pmid:2391654 |
| Lachapelle P et al. | The effect of iodoacetic acid on the electroretinogram and oscillatory potentials in rabbits. | 1990 | Doc Ophthalmol | pmid:2265579 |
| Rúa J et al. | Isocitrate lyase from Phycomyces blakesleeanus. The role of Mg2+ ions, kinetics and evidence for two classes of modifiable thiol groups. | 1990 | Biochem. J. | pmid:2268266 |
| Kohanski RA and Heinrikson RL | Primary structure of avian hepatic rhodanese. | 1990 | J. Protein Chem. | pmid:2275748 |
| Holtzer ME et al. | The effect of sulfhydryl blocking groups on the thermal unfolding of alpha alpha tropomyosin coiled coils. | 1990 | Biochem. Biophys. Res. Commun. | pmid:2306243 |
| Lakie M and Robson LG | Thixotropy in frog single muscle fibres. | 1990 | Exp. Physiol. | pmid:2310557 |
| Scotcher KP et al. | Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion on ATP levels of mouse brain synaptosomes. | 1990 | J. Neurochem. | pmid:2313288 |
| Reiner PB et al. | A pharmacological model of ischemia in the hippocampal slice. | 1990 | Neurosci. Lett. | pmid:2280893 |
| Miyazaki Y et al. | Selective turnover of sarcolemmal phospholipids with lethal cardiac myocyte injury. | 1990 | Am. J. Physiol. | pmid:2382705 |
| Oreffo VI et al. | Diamine uptake by rat lung type II cells in vitro. | 1991 | Biochem. Pharmacol. | pmid:2009096 |
| Spencer P et al. | The identification of a structurally important cysteine residue in the glycerol dehydrogenase from Bacillus stearothermophilus. | 1991 | Biochim. Biophys. Acta | pmid:2009285 |
| Florine-Casteel K et al. | Lipid order in hepatocyte plasma membrane blebs during ATP depletion measured by digitized video fluorescence polarization microscopy. | 1991 | FASEB J. | pmid:2010060 |
| Cannon JR et al. | The effects of fructose on adenosine triphosphate depletion following mitochondrial dysfunction and lethal cell injury in isolated rat hepatocytes. | 1991 | Toxicol. Appl. Pharmacol. | pmid:2020968 |
| Armstrong SC and Ganote CE | Effects of the phospholipase inhibitor mepacrine on injury in ischemic and metabolically inhibited adult isolated myocytes. | 1991 | Am. J. Pathol. | pmid:2000934 |
| Kempson SA et al. | Iodoacetate action on endocytic uptake of different fluid-phase markers by OK renal epithelial cells. | 1991 | Biochim. Biophys. Acta | pmid:2001415 |
| Konishi K and Fujioka M | Reversible inactivation of recombinant rat liver guanidinoacetate methyltransferase by glutathione disulfide. | 1991 | Arch. Biochem. Biophys. | pmid:1898065 |
| Lees GJ and Sandberg M | Evoked field potential changes in the rat hippocampus produced by toxic doses of glutamate agonists and metabolic inhibitors: correlation with subsequent neuronal death. | 1991 | Exp Brain Res | pmid:1680739 |
| Faix S et al. | Micropuncture study of the kidney in sheep: effects of iodoacetate on renal urea handling. | 1991 | Comp Biochem Physiol A Comp Physiol | pmid:1682092 |
| Baker MS et al. | Oxidation of articular cartilage glyceraldehyde-3-phosphate dehydrogenase (G3PDH) occurs in vivo during carrageenin-induced arthritis. | 1991 | Agents Actions | pmid:1862748 |
| Barron JT et al. | Differential effects of fatty acids on glycolysis and glycogen metabolism in vascular smooth muscle. | 1991 | Biochim. Biophys. Acta | pmid:1863593 |
| Kishi M et al. | Pharmacological characteristics of choline transport system in mouse cerebral cortical neurons in primary culture. | 1991 | Jpn. J. Pharmacol. | pmid:2067141 |
| Kembhavi AA et al. | Clostripain: characterization of the active site. | 1991 | FEBS Lett. | pmid:2044766 |
| Harrison DC et al. | A pH-dependent phospholipase A2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes. | 1991 | Biochem. Biophys. Res. Commun. | pmid:1899571 |
| Novak M et al. | Mesocestoides corti: a GC/MS study of the effects of oxaloacetate and iodoacetate on the isotope ratios in succinate and lactate excreted in the presence of NaH13CO3. | 1991 | Exp. Parasitol. | pmid:1847107 |
| Zeevalk GD and Nicklas WJ | Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition. | 1991 | J. Pharmacol. Exp. Ther. | pmid:1851840 |
| Perks AM et al. | Lung liquid production by in vitro lungs from fetal guinea pigs: studies with metabolic inhibitors. | 1991 | Can. J. Physiol. Pharmacol. | pmid:1756423 |
| Li W and Stanley ER | Role of dimerization and modification of the CSF-1 receptor in its activation and internalization during the CSF-1 response. | 1991 | EMBO J. | pmid:1825054 |
| Tóth G and Szabó G | Nucleotide and DNA uptake by Neurospora crassa: involvement of an uptake stimulating protein. | 1991 | Biochim. Biophys. Acta | pmid:1826455 |
| Saha N and Samuel AP | Characterization of glucose-6-phosphate dehydrogenase variants in the Sudan--including GdKhartoum, a hyperactive slow variant. | 1991 | Hum. Hered. | pmid:1828777 |
| Chen CY et al. | Inactivation of chicken mitochondrial phosphoenolpyruvate carboxykinase by o-phthalaldehyde. | 1991 | J. Biol. Chem. | pmid:1885594 |
| Lo RS et al. | An endogenous carrier-mediated uptake system for folate in oocytes of Xenopus laevis. | 1991 | Proc. Biol. Sci. | pmid:1685241 |
| Nasu T et al. | Changes in K(+)-induced contractions in ileal longitudinal smooth muscle of guinea-pig, induced by monoiodoacetic acid. | 1991 | J. Pharm. Pharmacol. | pmid:1685528 |
| Verity MA et al. | Paradoxical potentiation by low extracellular Ca2+ of acute chemical anoxic neuronal injury in cerebellar granule cell culture. | 1991 | Mol. Chem. Neuropathol. | pmid:1687239 |