| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stroke | D020521 | 32 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Hypocalcemia | D006996 | 12 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Thrombocytopenia | D013921 | 15 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
| Rickets | D012279 | 6 associated lipids |
| Blood Platelet Disorders | D001791 | 12 associated lipids |
| Byssinosis | D002095 | 11 associated lipids |
| Pre-Eclampsia | D011225 | 16 associated lipids |
| Vitamin D Deficiency | D014808 | 13 associated lipids |
| Vascular Diseases | D014652 | 16 associated lipids |
| Photosensitivity Disorders | D010787 | 8 associated lipids |
| Thymus Neoplasms | D013953 | 15 associated lipids |
| Blindness | D001766 | 6 associated lipids |
| Vitamin B 6 Deficiency | D026681 | 10 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Umbach AL and Siedow JN | The reaction of the soybean cotyledon mitochondrial cyanide-resistant oxidase with sulfhydryl reagents suggests that alpha-keto acid activation involves the formation of a thiohemiacetal. | 1996 | J. Biol. Chem. | pmid:8798784 |
| Han Z et al. | DNA-dependent protein kinase is a target for a CPP32-like apoptotic protease. | 1996 | J. Biol. Chem. | pmid:8798786 |
| Bell SD et al. | RNA molecules that bind to and inhibit the active site of a tyrosine phosphatase. | 1998 | J. Biol. Chem. | pmid:9603938 |
| Gan ZR and Wells WW | Identification and reactivity of the catalytic site of pig liver thioltransferase. | 1987 | J. Biol. Chem. | pmid:3571279 |
| Johnson EM et al. | Altered nucleosomes of active nucleolar chromatin contain accessible histone H3 in its hyperacetylated forms. | 1987 | J. Biol. Chem. | pmid:3584101 |
| Liao TH and Wadano A | Inactivation of DNase by 2-nitro-5-thiocyanobenzoic acid. II. Serine and threonine are the sites of reaction on the DNase molecule. | 1979 | J. Biol. Chem. | pmid:489555 |
| Odorzynski TW and Light A | Refolding of the mixed disulfide of bovine trypsinogen and glutathione. | 1979 | J. Biol. Chem. | pmid:438188 |
| Plishker GA et al. | Calcium-activated potassium transport and high molecular weight forms of calpromotin. | 1992 | J. Biol. Chem. | pmid:1400494 |
| Haniu M et al. | Structural analysis of NADPH-cytochrome P-450 reductase from porcine hepatic microsomes. Sequences of proteolytic fragments, cysteine-containing peptides, and a NADPH-protected cysteine peptide. | 1984 | J. Biol. Chem. | pmid:6438080 |
| Altschuld RA et al. | Degradation and resynthesis of adenine nucleotides in adult rat heart myocytes. | 1987 | J. Biol. Chem. | pmid:3654628 |
| Toll L and Howard BD | Evidence that an ATPase and a protonmotive force function in the transport of acetylcholine into storage vesicles. | 1980 | J. Biol. Chem. | pmid:6444415 |
| Dixon TE and Al-Awqati Q | H+/ATP stoichiometry of proton pump of turtle urinary bladder. | 1980 | J. Biol. Chem. | pmid:6444948 |
| Staswick PE et al. | Identification of the cystines which link the acidic and basic components of the glycinin subunits. | 1984 | J. Biol. Chem. | pmid:6541653 |
| Rao US and Scarborough GA | Chemical state of the cysteine residues in the Neurospora crassa plasma membrane H(+)-ATPase. | 1990 | J. Biol. Chem. | pmid:2139659 |
| Walker J et al. | Affinity chromatography of mammalian and yeast nucleosomes. Two modes of binding of transcriptionally active mammalian nucleosomes to organomercurial-agarose columns, and contrasting behavior of the active nucleosomes of yeast. | 1990 | J. Biol. Chem. | pmid:2180934 |
| Yeaton RW et al. | Calcium-mediated degradation of epidermal growth factor receptor in dislodged A431 cells and membrane preparations. | 1983 | J. Biol. Chem. | pmid:6307999 |
| de Vocht ML et al. | Structural and functional role of the disulfide bridges in the hydrophobin SC3. | 2000 | J. Biol. Chem. | pmid:10829014 |
| Plow EF and Collen D | Immunochemical characterization of a low affinity lysine binding site within plasminogen. | 1981 | J. Biol. Chem. | pmid:6793589 |
| Usui H et al. | Phosphoprotein phosphatases in human erythrocyte cytosol. | 1983 | J. Biol. Chem. | pmid:6309805 |
| Nelson NC and Taylor SS | Selective protection of sulfhydryl groups in cAMP-dependent protein kinase II. | 1983 | J. Biol. Chem. | pmid:6309827 |
| Bordji K et al. | Evidence for the presence of peroxisome proliferator-activated receptor (PPAR) alpha and gamma and retinoid Z receptor in cartilage. PPARgamma activation modulates the effects of interleukin-1beta on rat chondrocytes. | 2000 | J. Biol. Chem. | pmid:10766862 |
| Davenport JW and Slayman CW | The plasma membrane H+-ATPase of Neurospora crassa. Properties of two reactive sulfhydryl groups. | 1988 | J. Biol. Chem. | pmid:2903147 |
| Abramson SN et al. | Lophotoxin and related coral toxins covalently label the alpha-subunit of the nicotinic acetylcholine receptor. | 1988 | J. Biol. Chem. | pmid:2903863 |
| Porter MA and Hartman FC | Catalytic nonessentiality of an active-site cysteinyl residue of phosphoribulokinase. | 1988 | J. Biol. Chem. | pmid:2844788 |
| Andres HH et al. | On the active site of liver acetyl-CoA. Arylamine N-acetyltransferase from rapid acetylator rabbits (III/J). | 1988 | J. Biol. Chem. | pmid:2897358 |
| Ross DC and McIntosh DB | Intramolecular cross-linking of domains at the active site links A1 and B subfragments of the Ca2+-ATPase of sarcoplasmic reticulum. | 1987 | J. Biol. Chem. | pmid:2950084 |
| Suzuki K et al. | Mercuric and cadmium ions stimulate phosphorylation of band 4.2 protein on human erythrocyte membranes. | 1985 | J. Biol. Chem. | pmid:2984208 |
| Camici G et al. | The complete amino acid sequence of the low molecular weight cytosolic acid phosphatase. | 1989 | J. Biol. Chem. | pmid:2644264 |
| Morino Y et al. | Selective inactivation of pyridoxamine form of aspartate aminotransferase by iodoacetate. Carboxymethylation of 4'-amino group of bound pyridoxamine 5'-phosphate. | 1978 | J. Biol. Chem. | pmid:681337 |
| Gottschalk WK and Sonneborn DR | Evidence that Blastocladiella emersonii zoospore maintenance factor is a sulfhydryl group-containing cyclic ribotide. | 1985 | J. Biol. Chem. | pmid:3997839 |
| Samy TS et al. | Primary structure of macromomycin, an antitumor antibiotic protein. | 1983 | J. Biol. Chem. | pmid:6848492 |
| King MM | Modification of the calmodulin-stimulated phosphatase, calcineurin, by sulfhydryl reagents. | 1986 | J. Biol. Chem. | pmid:3949803 |
| Schmidt SY | Phosphatidylinositol synthesis and phosphorylation are enhanced by light in rat retinas. | 1983 | J. Biol. Chem. | pmid:6853507 |
| Hausinger RP and Howard JB | Thiol reactivity of the nitrogenase Fe-protein from Azotobacter vinelandii. | 1983 | J. Biol. Chem. | pmid:6580291 |
| Goverman JM and Pierce JG | Differential effects of alkylation of methionine residues on the activities of pituitary thyrotropin and lutropin. | 1981 | J. Biol. Chem. | pmid:6270085 |
| Okamura-Ikeda K et al. | An essential cysteine residue located in the vicinity of the FAD-binding site in short-chain, medium-chain, and long-chain acyl-CoA dehydrogenases from rat liver mitochondria. | 1985 | J. Biol. Chem. | pmid:3968065 |
| Kleanthous C et al. | Active site labeling of the shikimate pathway enzyme, dehydroquinase. Evidence for a common substrate binding site within dehydroquinase and dehydroquinate synthase. | 1990 | J. Biol. Chem. | pmid:2193027 |
| Kleanthous C and Coggins JR | Reversible alkylation of an active site methionine residue in dehydroquinase. | 1990 | J. Biol. Chem. | pmid:2193028 |
| Connett RJ | In vivo glycolytic equilibria in dog gracilis muscle. | 1985 | J. Biol. Chem. | pmid:3972826 |
| Seelig GF and Folk JE | Half-of-the-sites and all-of-the-sites reactivity in human plasma blood coagulation factor XIIIa. | 1980 | J. Biol. Chem. | pmid:6107293 |
| Chambers JE et al. | The reduction potential of the active site disulfides of human protein disulfide isomerase limits oxidation of the enzyme by Ero1α. | 2010 | J. Biol. Chem. | pmid:20657012 |
| First EA and Taylor SS | Subunit interaction sites between the regulatory and catalytic subunits of cAMP-dependent protein kinase. Heterobifunctional cross-linking reagents lead to photodependent and photoindependent cross-linking. | 1988 | J. Biol. Chem. | pmid:2833497 |
| Yep A et al. | Identification and characterization of a critical region in the glycogen synthase from Escherichia coli. | 2004 | J. Biol. Chem. | pmid:14665620 |
| Light A and Fonseca P | The preparation and properties of the catalytic subunit of bovine enterokinase. | 1984 | J. Biol. Chem. | pmid:6386810 |
| Holmgren A and Fagerstedt M | The in vivo distribution of oxidized and reduced thioredoxin in Escherichia coli. | 1982 | J. Biol. Chem. | pmid:7045097 |
| Misono KS and Inagami T | Structure of mouse submaxillary gland renin. Identification of two disulfide-linked polypeptide chains and the complete amino acid sequence of the light chain. | 1982 | J. Biol. Chem. | pmid:7045107 |
| Adler S and Modrich P | T7-induced DNA polymerase. Requirement for thioredoxin sulfhydryl groups. | 1983 | J. Biol. Chem. | pmid:6343383 |
| Sumi H and Robbins KC | A functionally active heavy chain derived from human high molecular weight urokinase. | 1983 | J. Biol. Chem. | pmid:6345538 |
| Kallis GB and Holmgren A | Differential reactivity of the functional sulfhydryl groups of cysteine-32 and cysteine-35 present in the reduced form of thioredoxin from Escherichia coli. | 1980 | J. Biol. Chem. | pmid:7000775 |
| Nagahara N and Katayama A | Post-translational regulation of mercaptopyruvate sulfurtransferase via a low redox potential cysteine-sulfenate in the maintenance of redox homeostasis. | 2005 | J. Biol. Chem. | pmid:16107337 |
| Olstein AD and Liener IE | Comparative studies of mouse liver cathepsin B and an analogous tumor thiol proteinase. | 1983 | J. Biol. Chem. | pmid:6350300 |
| Wermuth B | Purification and properties of an NADPH-dependent carbonyl reductase from human brain. Relationship to prostaglandin 9-ketoreductase and xenobiotic ketone reductase. | 1981 | J. Biol. Chem. | pmid:7005231 |
| Cogoli-Greuter M and Christen P | Formation of hydroxypyruvaldehyde phosphate in human erythrocytes. | 1981 | J. Biol. Chem. | pmid:7016859 |
| Gleisner JM and Blakley RL | The structure of dihydrofolate reductase. I. Inactivation of bacterial dihydrofolate reductase concomitant with modification of a methionine residue at the active site. | 1975 | J. Biol. Chem. | pmid:1112818 |
| Chen CY et al. | Inactivation of chicken mitochondrial phosphoenolpyruvate carboxykinase by o-phthalaldehyde. | 1991 | J. Biol. Chem. | pmid:1885594 |
| Jakes KS et al. | Alteration of the pH-dependent ion selectivity of the colicin E1 channel by site-directed mutagenesis. | 1990 | J. Biol. Chem. | pmid:1691183 |
| Sorrentino S et al. | Eosinophil-derived neurotoxin and human liver ribonuclease. Identity of structure and linkage of neurotoxicity to nuclease activity. | 1992 | J. Biol. Chem. | pmid:1634526 |
| Schopfer LM et al. | Active site probes of flavoproteins. Determination of the solvent accessibility of the flavin position 8 for a series of flavoproteins. | 1981 | J. Biol. Chem. | pmid:6894755 |
| Sorrentino S et al. | Purification and characterization of a ribonuclease from human liver. | 1988 | J. Biol. Chem. | pmid:3182786 |
| Thorstensen K | Hepatocytes and reticulocytes have different mechanisms for the uptake of iron from transferrin. | 1988 | J. Biol. Chem. | pmid:3182815 |
| Schäffer J et al. | Glutathione transferase from bovine placenta. Preparation, biochemical characterization, crystallization, and preliminary crystallographic analysis of a neutral class PI enzyme. | 1988 | J. Biol. Chem. | pmid:3182852 |
| Horowitz PM and Criscimagna NL | Sulfhydryl-directed triggering of conformational changes in the enzyme rhodanese. | 1988 | J. Biol. Chem. | pmid:3164722 |
| Ikemoto A et al. | Glycolysis and glutamate accumulation into synaptic vesicles. Role of glyceraldehyde phosphate dehydrogenase and 3-phosphoglycerate kinase. | 2003 | J. Biol. Chem. | pmid:12488440 |
| Jung J et al. | Interaction of cofilin with triose-phosphate isomerase contributes glycolytic fuel for Na,K-ATPase via Rho-mediated signaling pathway. | 2002 | J. Biol. Chem. | pmid:12359716 |
| Poole B and Wibo M | Protein degradation in cultured cells. The effect of fresh medium, fluoride, and iodoacetate on the digestion of cellular protein of rat fibroblasts. | 1973 | J. Biol. Chem. | pmid:4737734 |
| Springer TA et al. | Submit and disulfide structure of monomeric and dimeric forms of detergent-soluble HLA antigens. | 1977 | J. Biol. Chem. | pmid:873911 |
| Maithal K et al. | Inhibition of plasmodium falciparum triose-phosphate isomerase by chemical modification of an interface cysteine. Electrospray ionization mass spectrometric analysis of differential cysteine reactivities. | 2002 | J. Biol. Chem. | pmid:12006590 |
| Weng L et al. | Active site cysteinyl and arginyl residues of rhodanese. A novel formation of disulfide bonds in the active site promoted by phenylglyoxal. | 1978 | J. Biol. Chem. | pmid:711738 |
| Makinen AL and Nowak T | A reactive cysteine in avian liver phosphoenolpyruvate carboxykinase. | 1989 | J. Biol. Chem. | pmid:2545699 |
| Kuehl GV et al. | Tryptophanyl transfer ribonucleic acid synthetase of Escherichia coli. Character of required thiol group and structure of thiol peptides. | 1976 | J. Biol. Chem. | pmid:776964 |
| Tavazzi B et al. | Oxidative stress induces impairment of human erythrocyte energy metabolism through the oxygen radical-mediated direct activation of AMP-deaminase. | 2001 | J. Biol. Chem. | pmid:11675377 |
| Dunten RL and Cohen RE | Recognition of modified forms of ribonuclease A by the ubiquitin system. | 1989 | J. Biol. Chem. | pmid:2550456 |
| Dahlman K et al. | High level expression in Escherichia coli of the DNA-binding domain of the glucocorticoid receptor in a functional form utilizing domain-specific cleavage of a fusion protein. | 1989 | J. Biol. Chem. | pmid:2642905 |
| Moore MA et al. | Evidence for the existence of covalent nucleotide-thymidylate synthase complexes, identification of site of attachment, and enhancement by folates. | 1986 | J. Biol. Chem. | pmid:3745210 |
| Beinfeld MC et al. | Characterization of an endoprotease from rat small intestinal mucosal secretory granules which generates somatostatin-28 from prosomatostatin by cleavage after a single arginine residue. | 1989 | J. Biol. Chem. | pmid:2564394 |
| Zhou G et al. | The catalytic role of Cys124 in the dual specificity phosphatase VHR. | 1994 | J. Biol. Chem. | pmid:7961745 |
| Gomi T et al. | S-adenosylhomocysteinase from rat liver. Amino acid sequences of the peptides containing active site cysteine residues modified by treatment with 5'-p-fluorosulfonylbenzoyladenosine. | 1986 | J. Biol. Chem. | pmid:3759971 |
| Egger S et al. | Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates. | 2012 | J. Biol. Chem. | pmid:22123821 |
| Cuypers HT et al. | Sulfhydryl content of bovine eye lens leucine aminopeptidase. Determination of the reactivity of the sulfhydryl groups of the zinc metalloenzyme, of the enzyme activated by Mg2+, Mn2+, and Co2+, and of the metal-free apoenzyme. | 1982 | J. Biol. Chem. | pmid:7085617 |
| Shivaprasad S and Wetzel R | Scanning cysteine mutagenesis analysis of Abeta-(1-40) amyloid fibrils. | 2006 | J. Biol. Chem. | pmid:16263715 |
| James AD et al. | The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP. | 2015 | J. Biol. Chem. | pmid:26294767 |
| Yang JH et al. | Glycolytic oscillations in isolated rabbit ventricular myocytes. | 2008 | J. Biol. Chem. | pmid:18948270 |
| Rawlings ND et al. | Asparagine peptide lyases: a seventh catalytic type of proteolytic enzymes. | 2011 | J. Biol. Chem. | pmid:21832066 |
| Teng H et al. | Conserved cysteine residues of histidinol dehydrogenase are not involved in catalysis. Novel chemistry required for enzymatic aldehyde oxidation. | 1993 | J. Biol. Chem. | pmid:8314784 |
| Leong JM et al. | A 76-amino acid disulfide loop in the Yersinia pseudotuberculosis invasin protein is required for integrin receptor recognition. | 1993 | J. Biol. Chem. | pmid:8376409 |
| Poulose AJ et al. | Cloning and sequencing of the cDNA for S-acyl fatty acid synthase thioesterase from the uropygial gland of mallard duck. | 1985 | J. Biol. Chem. | pmid:2415525 |
| Zaager S and Burke M | Subunit interactions of skeletal muscle myosin and myosin subfragment 1. Evidence for heavy chain-alkali light chain association-dissociation equilibrium. | 1988 | J. Biol. Chem. | pmid:3335556 |
| Dennis PA et al. | Alpha 2-macroglobulin is a binding protein for basic fibroblast growth factor. | 1989 | J. Biol. Chem. | pmid:2468667 |
| Hunt J et al. | Redox potentials of milk xanthine dehydrogenase. Room temperature measurement of the FAD and 2Fe/2S center potentials. | 1993 | J. Biol. Chem. | pmid:8395516 |
| Kovacic PB et al. | New insights into cytosolic glucose levels during differentiation of 3T3-L1 fibroblasts into adipocytes. | 2011 | J. Biol. Chem. | pmid:21349852 |
| Abrahamson M et al. | Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin. | 1987 | J. Biol. Chem. | pmid:3496337 |
| Rogers GA et al. | Facile alkylation of methionine by benzyl bromide and demonstration of fumarase inactivation accompanied by alkylation of a methionine residue. | 1976 | J. Biol. Chem. | pmid:9397 |
| Lee BJ et al. | Identification of a selenocysteyl-tRNA(Ser) in mammalian cells that recognizes the nonsense codon, UGA. | 1989 | J. Biol. Chem. | pmid:2498338 |
| Plank DW et al. | Cysteine labeling studies of beef heart aconitase containing a 4Fe, a cubane 3Fe, or a linear 3Fe cluster. | 1989 | J. Biol. Chem. | pmid:2511202 |
| Carlberg I and Mannervik B | Reduction of 2,4,6-trinitrobenzenesulfonate by glutathione reductase and the effect of NADP+ on the electron transfer. | 1986 | J. Biol. Chem. | pmid:3003077 |
| Fontan E and Truffa-Bachi P | The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. Carboxymethylation of the enzyme: threonine binding and inhibition are functionally dissociable. | 1978 | J. Biol. Chem. | pmid:344322 |
| Grifantini R et al. | Topological mapping of the cysteine residues of N-carbamyl-D-amino-acid amidohydrolase and their role in enzymatic activity. | 1996 | J. Biol. Chem. | pmid:8621596 |
| Kakinuma Y and Igarashi K | Active potassium extrusion regulated by intracellular pH in Streptococcus faecalis. | 1988 | J. Biol. Chem. | pmid:2459118 |
| Gal S and Gottesman MM | The major excreted protein of transformed fibroblasts is an activable acid-protease. | 1986 | J. Biol. Chem. | pmid:3511049 |
| Jones MD et al. | Refolding and oxidation of recombinant human stem cell factor produced in Escherichia coli. | 1996 | J. Biol. Chem. | pmid:8626682 |