Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Cumulative Trauma Disorders D012090 2 associated lipids
Monckeberg Medial Calcific Sclerosis D050380 1 associated lipids
Clonorchiasis D003003 1 associated lipids
Osteoarthritis, Spine D055013 2 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Baskova IP and Nikonov GI [Destabilase: an enzyme of medicinal leech salivary gland secretion hydrolyzes the isopeptide bonds in stabilized fibrin]. 1985 Biokhimiia pmid:3922436
Lokshina LA et al. [Isolation of a neutral histone-hydrolyzing protease from bovine spleen]. 1976 Biokhimiia pmid:1030647
Zorin NA and Gogotov IN [Hydrogenase activity in Thiocapsa roseopersicina according to the D2--H20 metabolic reaction]. 1975 Jan-Feb Biokhimiia pmid:1138996
Egorova OA et al. [Isolation and properties of NAD-dependent formate dehydrogenase from the yeast Candida methylica]. 1981 Biokhimiia pmid:7260197
Sokolov NN and Nikolaev AIa [Sulfhydryl groups of L-asparaginase A from Pseudomonas fluorescens AG]. 1976 Biokhimiia pmid:14736
Guiraud P et al. Cultured human skin fibroblasts absorb 65Zn. Optimization of the method and study of the mechanisms involved. 1992 Jan-Mar Biol Trace Elem Res pmid:1375058
SCOTT GT and HAYWARD HR The influence of the glycolytic inhibitor iodoacetic acid on aging and on the potassium and sodium content of the egg cells of Mactra solidissima. 1950 Biol. Bull. pmid:14791537
Aurich H et al. [Kinetics of membrane-bound aldehyde dehydrogenase from Acinetobacter calcoaceticus]. 1987 Biol. Chem. Hoppe-Seyler pmid:3566912
Gehrke PP and Jennissen HP ATP-dependent proteolysis and the role of ubiquitin in rabbit cardiac muscle. 1987 Biol. Chem. Hoppe-Seyler pmid:3040036
Buttle DJ et al. The preparation of fully active chymopapain free of contaminating proteinases. 1990 Biol. Chem. Hoppe-Seyler pmid:2085414
Wada M and Shirahata A Conformational stabilization of rat s-adenosylmethionine decarboxylase by putrescine. 2010 Biol. Pharm. Bull. pmid:21048303
Choi HS et al. Protective Effect of Deer Bone Oil on Cartilage Destruction in Rats with Monosodium Iodoacetate (MIA)-Induced Osteoarthritis. 2016 Biol. Pharm. Bull. pmid:27904047
Adekunle AO et al. Guinea pig testicular proacrosin-acrosin system: further characterization of the active enzyme. 1989 Biol. Reprod. pmid:2493819
Xu YK et al. The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritis. 2015 Biol. Res. pmid:26578310
Serban MA and Prestwich GD Synthesis of hyaluronan haloacetates and biology of novel cross-linker-free synthetic extracellular matrix hydrogels. 2007 Biomacromolecules pmid:17696398
Tomoda A et al. Accumulation of inosine 5'-monophosphate in human erythrocytes incubated with inosine. 1987 Biomed. Biochim. Acta pmid:2439075
Shellhaas J et al. Effect of a sulfhydryl inhibitor on in vitro bone marrow colonies (CFU-c). 1977 Biomedicine pmid:606308
Seliuchenko OA et al. [Topography of cysteine residues in DNA-dependent RNA-polymerase]. 1985 Bioorg. Khim. pmid:3890863
Chertov OIu et al. [The role of sulfhydryl groups in the functioning of DNA-dependent RNA-polymerase]. 1985 Bioorg. Khim. pmid:2408626
Brooke DG et al. Targeting the Warburg Effect in cancer; relationships for 2-arylpyridazinones as inhibitors of the key glycolytic enzyme 6-phosphofructo-2-kinase/2,6-bisphosphatase 3 (PFKFB3). 2014 Bioorg. Med. Chem. pmid:24398380
Suna H et al. Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death. 2009 Bioorg. Med. Chem. pmid:19414266
Wu Y et al. Changes in membrane properties during energy depletion-induced cell injury studied with fluorescence microscopy. 1996 Biophys. J. pmid:8804592
Schwarz RP et al. Caffeine contracture and iodoacetate rigor in frog skeletal muscle. A comparison. 1978 Biophys. J. pmid:667298
Shin HH and Choi HS Purification and characterization of cysteine protease from Pleurotus ostreatus. 1998 Biosci. Biotechnol. Biochem. pmid:9720226
Sugisawa T and Hoshino T Purification and properties of membrane-bound D-sorbitol dehydrogenase from Gluconobacter suboxydans IFO 3255. 2002 Biosci. Biotechnol. Biochem. pmid:11866120
Ueatrongchit T et al. Purification and characterization of a novel (R)-hydroxynitrile lyase from Eriobotrya japonica (Loquat). 2008 Biosci. Biotechnol. Biochem. pmid:18540101
Arima K et al. Purification and some properties of an aminopeptidase from the seeds of Cannabis sativa. 2000 Biosci. Biotechnol. Biochem. pmid:10879480
Nagano H and To KA Purification of collagenase and specificity of its related enzyme from Bacillus subtilis FS-2. 2000 Biosci. Biotechnol. Biochem. pmid:10705465
Hiwatashi K et al. Purification and characterization of a novel prolyl aminopeptidase from Maitake (Grifola frondosa). 2004 Biosci. Biotechnol. Biochem. pmid:15215614
Ito K et al. Novel aminopeptidase specific for glycine from Actinomucor elegans. 2003 Biosci. Biotechnol. Biochem. pmid:12619677
Mizuno Y et al. Cysteine synthase of an extremely thermophilic bacterium, Thermus thermophilus HB8. 2002 Biosci. Biotechnol. Biochem. pmid:12005048
Bezawada J et al. Recovery of Bacillus licheniformis Alkaline Protease from Supernatant of Fermented Wastewater Sludge Using Ultrafiltration and Its Characterization. 2011 Biotechnol Res Int pmid:21876816
Khan SA and Iqbal J Polyclonal-antibody-mediated insolubilization and stabilization of papain. 2000 Biotechnol. Appl. Biochem. pmid:11001869
Lukashin VG et al. [Functional restructuring of the bush-like receptor during the suppression of anaerobic glycolysis]. 1989 Biull Eksp Biol Med pmid:2785827
Sidorenkov IV and Sharaev PN [Effect of cholesterol and monoiodoacetate on hexosamine synthetase activity and also on the content of hexosamines and hexuronic acids in the aortal wall]. 1973 Biull Eksp Biol Med pmid:4774434
Magomedov NM et al. [Study of lipid peroxidation in experimental retinal degeneration]. 1983 Biull Eksp Biol Med pmid:6830982
Gushchin IS and Zebrev AI [Characteristics of the effect of ketotifen on the selective and non-selective histamine release from human basophils]. 1984 Biull Eksp Biol Med pmid:6198010
Gasanov GG et al. [Oscillatory evoked potentials in the rabbit visual system during experimental retinal pathology induced by administration of monoiodoacetic acid]. 1985 Biull Eksp Biol Med pmid:4041592
Sugiyama T et al. A novel platelet aggregating factor found in a patient with defective collagen-induced platelet aggregation and autoimmune thrombocytopenia. 1987 Blood pmid:3580576
Lew VL et al. Effects of age-dependent membrane transport changes on the homeostasis of senescent human red blood cells. 2007 Blood pmid:17456724
Grignani G and Jamieson GA Platelets in tumor metastasis: generation of adenosine diphosphate by tumor cells is specific but unrelated to metastatic potential. 1988 Blood pmid:2833329
Abrahamsen J and Nedergaard OA Accumulation of 3H-adrenaline by rabbit aorta. 1985 Blood Vessels pmid:3967097
Jinka R et al. Purification and characterization of cysteine protease from germinating cotyledons of horse gram. 2009 BMC Biochem. pmid:19919695
Oliveira SC et al. Modulation of the pharmacological effects of enzymatically-active PLA2 by BTL-2, an isolectin isolated from the Bryothamnion triquetrum red alga. 2008 BMC Biochem. pmid:18534036
Petersen SV et al. The subunit composition of human extracellular superoxide dismutase (EC-SOD) regulates enzymatic activity. 2007 BMC Biochem. pmid:17937792
Wudayagiri R et al. Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus. 2001 BMC Biochem. pmid:11782289
Phrommao E et al. A novel subtilase with NaCl-activated and oxidant-stable activity from Virgibacillus sp. SK37. 2011 BMC Biotechnol. pmid:21658261
Nykopp TK et al. Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan content. 2009 BMC Cancer pmid:19435493
Jia D et al. Fibronectin matrix-mediated cohesion suppresses invasion of prostate cancer cells. 2012 BMC Cancer pmid:22433434
Eby WM et al. Hyperbolastic modeling of tumor growth with a combined treatment of iodoacetate and dimethylsulphoxide. 2010 BMC Cancer pmid:20863400
Le Bihan-Duval E et al. Chicken meat quality: genetic variability and relationship with growth and muscle characteristics. 2008 BMC Genet. pmid:18706119
Cherel P et al. Joint analysis of quantitative trait loci and major-effect causative mutations affecting meat quality and carcass composition traits in pigs. 2011 BMC Genet. pmid:21875434
Liao HH et al. Down-regulation of granulocyte-macrophage colony-stimulating factor by 3C-like proteinase in transfected A549 human lung carcinoma cells. 2011 BMC Immunol. pmid:21324206
Gigliobianco T et al. Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. 2010 BMC Microbiol. pmid:20492686
Santos SB et al. The use of antibiotics to improve phage detection and enumeration by the double-layer agar technique. 2009 BMC Microbiol. pmid:19627589
Herrmann L et al. Biochemical and molecular characterisation of Tetrahymena thermophila extracellular cysteine proteases. 2006 BMC Microbiol. pmid:16507097
Orita S et al. Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain. 2011 BMC Musculoskelet Disord pmid:21679434
Miyamoto S et al. Intra-articular injection of mono-iodoacetate induces osteoarthritis of the hip in rats. 2016 BMC Musculoskelet Disord pmid:26992380
Vera PL and Meyer-Siegler KL Anatomical location of macrophage migration inhibitory factor in urogenital tissues, peripheral ganglia and lumbosacral spinal cord of the rat. 2003 BMC Neurosci pmid:12908877
Beauvieux MC et al. Some processes of energy saving and expenditure occurring during ethanol perfusion in the isolated liver of fed rats; a Nuclear Magnetic Resonance study. 2004 BMC Physiol. pmid:15053831
Faure G et al. Characterization of a human coagulation factor Xa-binding site on Viperidae snake venom phospholipases A2 by affinity binding studies and molecular bioinformatics. 2007 BMC Struct. Biol. pmid:18062812
Edwards TE et al. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. 2011 BMC Struct. Biol. pmid:21995815
Vera PL and Meyer-Siegler KL Substance P induces localization of MIF/alpha1-inhibitor-3 complexes to umbrella cells via paracellular transit through the urothelium in the rat bladder. 2006 BMC Urol pmid:16981995
Liotti FS and Locci P Onset and growth rate of solid tumours derived from implanted ascites tumour cells pretreated with ascorbic acid. 1986 Boll Ist Sieroter Milan pmid:3718681
Ramp WK et al. Effects of vitamin D deprivation and 1,25-dihydroxyvitamin D3 treatment on ion release from rat tibiae in vitro. 1986 Bone Miner pmid:3508714
Yamauchi Y et al. Correlation between high-resolution optical coherence tomography (OCT) images and histopathology in an iodoacetic acid-induced model of retinal degeneration in rabbits. 2011 Br J Ophthalmol pmid:21030415
JACKSON H Thermal coagulability of serum proteins and the diagnosis of malignant disease. 1950 Br Med J pmid:14777910
Wrathmell AB and Alexander P Immunogenicity of a rat leukaemia of spontaneous origin (SAL). 1976 Br. J. Cancer pmid:769814
Marks F and Fürstenberger G Experimental evidence that skin carcinogenesis is a multistep phenomenon. 1986 Br. J. Dermatol. pmid:3091063
Atterwill CK et al. Development of markers for cholinergic neurones in re-aggregate cultures of foetal rat whole brain in serum-containing and serum-free media: effects of triiodothyronine (T3). 1984 Br. J. Pharmacol. pmid:6487898
Boullin DJ and O'Brien RA Accumulation of quinidine by human blood platelets: effects on platelet ultrastructure and 5-hydroxytryptamine. 1971 Br. J. Pharmacol. pmid:5580696
Ahtee L et al. Transport of taurine by normal human blood platelets. 1974 Br. J. Pharmacol. pmid:4451820
Bley KR et al. RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists. 2006 Br. J. Pharmacol. pmid:16331286
Garcia AG and Kirpekar SM Release of noradrenaline from the cat spleen by sodium deprivation. 1973 Br. J. Pharmacol. pmid:4124979
Campbell IC and Todrick A On the pharmacology and biochemistry of the amine-uptake mechanism in human blood platelets. 1973 Br. J. Pharmacol. pmid:4152219
Lawrence CL et al. Effect of metabolic inhibition on glimepiride block of native and cloned cardiac sarcolemmal K(ATP) channels. 2002 Br. J. Pharmacol. pmid:12086984
Lawrence CL et al. The KATP channel opener diazoxide protects cardiac myocytes during metabolic inhibition without causing mitochondrial depolarization or flavoprotein oxidation. 2001 Br. J. Pharmacol. pmid:11588107
Burston JJ et al. Robust anti-nociceptive effects of monoacylglycerol lipase inhibition in a model of osteoarthritis pain. 2016 Br. J. Pharmacol. pmid:27501482
Chi CH and Dixit BN Characterization of (+/-)-methadone uptake by rat lung. 1977 Br. J. Pharmacol. pmid:15696
Gault NF et al. Effect of some electrical stimulation variables on wing flapping, post-mortem glycolysis and eating quality characteristics of broiler pectoralis major muscle. 2000 Br. Poult. Sci. pmid:11081423
Madry C et al. The role of pannexin hemichannels in the anoxic depolarization of hippocampal pyramidal cells. 2010 Brain pmid:20940167
Adams EM et al. Lack of [3H]quinuclidinyl benzylate binding to biologically relevant binding sites on mononuclear cells. 1992 Brain Behav. Immun. pmid:1392105
Ando M and Itoh T Changes of amino acid by the deprivation of energy sources in the cerebral cortex. 1989 Brain Dev. pmid:2751063
O'Dowd BS et al. Astrocytes implicated in the energizing of intermediate memory processes in neonate chicks. 1994 Brain Res Cogn Brain Res pmid:7833696
Chang TK and Cheng JT Inhibitory effect of xylamine on the uptake of [3H]norepinephrine into primary astrocyte cultures. 1992 Brain Res. pmid:1477731
Andersen BJ and Marmarou A Functional compartmentalization of energy production in neural tissue. 1992 Brain Res. pmid:1511302
Sorimachi M and Yamagami K Partial metabolic inhibition stimulates adrenal medullary secretion possibly by activating Na-dependent Ca influx mechanism. 1983 Brain Res. pmid:24010181
Daval JL et al. Release of [14C]adenosine derivatives from superfused synaptosome preparations. Effects of depolarizing agents and metabolic inhibitors. 1980 Brain Res. pmid:7350951
Pannicke T et al. A function of delayed rectifier potassium channels in glial cells: maintenance of an auxiliary membrane potential under pathological conditions. 2000 Brain Res. pmid:10799684
Saito T Glucose-supported oxidative metabolism and evoked potentials are sensitive to fluoroacetate, an inhibitor of glial tricarboxylic acid cycle in the olfactory cortex slice. 1990 Brain Res. pmid:2073603
Wakade AR and Wakade TD Sympathetic neurons grown in culture generate ATP by glycolysis: correlation between ATP content and [3H]norepinephrine uptake and storage. 1985 Brain Res. pmid:4075161
Maher P et al. A novel approach to screening for new neuroprotective compounds for the treatment of stroke. 2007 Brain Res. pmid:17765210
Perez E et al. Neuroprotective effects of an estratriene analog are estrogen receptor independent in vitro and in vivo. 2005 Brain Res. pmid:15757637
Reshef A et al. Preconditioning of primary rat neuronal cultures against ischemic injury: characterization of the "time window of protection'. 1996 Brain Res. pmid:9001730
Roberts EL Glycolysis and recovery of potassium ion homeostasis and synaptic transmission in hippocampal slices after anoxia or stimulated potassium release. 1993 Brain Res. pmid:8396493
Olesen SP Rapid increase in blood-brain barrier permeability during severe hypoxia and metabolic inhibition. 1986 Brain Res. pmid:3485464
Martínez AD and Sáez JC Regulation of astrocyte gap junctions by hypoxia-reoxygenation. 2000 Brain Res. Brain Res. Rev. pmid:10751675
Rice GE and Barnea A Copper-induced release of immunoreactive alpha-melanotropin from isolated hypothalamic granules. 1983 Brain Res. Bull. pmid:6667383
O'Dowd BS et al. Astrocytic glycogenolysis energizes memory processes in neonate chicks. 1994 Brain Res. Dev. Brain Res. pmid:8004768
Jezek P et al. Important amino acid residues of potato plant uncoupling protein (StUCP). 2000 Braz. J. Med. Biol. Res. pmid:11105092