Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Arthritis, Experimental D001169 24 associated lipids
Osteoarthritis D010003 4 associated lipids
Coronary Disease D003327 70 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Glioma D005910 112 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lymphoma D008223 18 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Brain Edema D001929 20 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Chave KJ et al. Site-directed mutagenesis establishes cysteine-110 as essential for enzyme activity in human gamma-glutamyl hydrolase. 1999 Biochem. J. pmid:10527932
Patel AB et al. Arginine acts as a protective and reversal agent against glycolytic inhibitors in spermatozoa. 1999 Physiol Chem Phys Med NMR pmid:10535103
Lai SL et al. Interprotein disulfide bonds formed during isolation process tighten the structure of the postsynaptic density. 1999 J. Neurochem. pmid:10537073
Dirksen TR et al. Effect of metabolic inhibitors on bone lipid synthesis from radioactive bases. 1975 Sep-Oct J. Dent. Res. pmid:1058850
Chang YS et al. Shear-induced increase in hydraulic conductivity in endothelial cells is mediated by a nitric oxide-dependent mechanism. 2000 Arterioscler. Thromb. Vasc. Biol. pmid:10634798
Malcolm CS et al. Characterization of iodoacetate-mediated neurotoxicity in vitro using primary cultures of rat cerebellar granule cells. 2000 Free Radic. Biol. Med. pmid:10656296
Sinclair CJ et al. Stimulation of nucleoside efflux and inhibition of adenosine kinase by A1 adenosine receptor activation. 2000 Biochem. Pharmacol. pmid:10660114
Kim JS and Southard JH Effect of phospholipase A2 inhibitors on the release of arachidonic acid and cell viability in cold-stored hepatocytes. 2000 Cryobiology pmid:10679147
Yoshioka K et al. Characteristics of monocarboxylates as energy substrates other than glucose in rat brain slices and the effect of selective glial poisoning - a 31P NMR study. 2000 Neurosci. Res. pmid:10683525
Nagano H and To KA Purification of collagenase and specificity of its related enzyme from Bacillus subtilis FS-2. 2000 Biosci. Biotechnol. Biochem. pmid:10705465