Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Hypocalcemia D006996 12 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Osteoarthritis, Knee D020370 13 associated lipids
Thrombocytopenia D013921 15 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Vascular Diseases D014652 16 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Lymphoma D008223 18 associated lipids
Brain Edema D001929 20 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Ferland CE et al. Antinociceptive effects of eugenol evaluated in a monoiodoacetate-induced osteoarthritis rat model. 2012 Phytother Res pmid:23015356
Camboim EK et al. Defluorination of sodium fluoroacetate by bacteria from soil and plants in Brazil. 2012 ScientificWorldJournal pmid:22619595
Downs I et al. The ROS scavenger, NAC, regulates hepatic Vα14iNKT cells signaling during Fas mAb-dependent fulminant liver failure. 2012 PLoS ONE pmid:22701598
Saba J et al. Increasing the productivity of glycopeptides analysis by using higher-energy collision dissociation-accurate mass-product-dependent electron transfer dissociation. 2012 Int J Proteomics pmid:22701174
Kaneda T et al. Key role of glycogen storage in high K+-induced contraction of the smooth muscles of the bovine trachea. 2012 J. Vet. Med. Sci. pmid:22673054
Mikulíková K et al. Study of saiga horn using high-performance liquid chromatography with mass spectrometry. 2012 ScientificWorldJournal pmid:22629195
Trivedi M et al. Improving the stability of the EC1 domain of E-cadherin by thiol alkylation of the cysteine residue. 2012 Int J Pharm pmid:22531851
Du J et al. The protein partners of GTP cyclohydrolase I in rat organs. 2012 PLoS ONE pmid:22479495
Kim JK et al. Effect of GCSB-5, a Herbal Formulation, on Monosodium Iodoacetate-Induced Osteoarthritis in Rats. 2012 Evid Based Complement Alternat Med pmid:22474519
Ford AP In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization. 2012 Purinergic Signal. pmid:22095157
Wang H et al. Proteomic analysis of early-responsive redox-sensitive proteins in Arabidopsis. 2012 J. Proteome Res. pmid:22050424
Kelly S et al. Spinal nociceptive reflexes are sensitized in the monosodium iodoacetate model of osteoarthritis pain in the rat. 2013 Osteoarthr. Cartil. pmid:23973147
Mapp PI et al. Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis. 2013 Osteoarthr. Cartil. pmid:23973148
Lee J et al. Coenzyme Q10 ameliorates pain and cartilage degradation in a rat model of osteoarthritis by regulating nitric oxide and inflammatory cytokines. 2013 PLoS ONE pmid:23894457
Wang XD et al. Estrogen aggravates iodoacetate-induced temporomandibular joint osteoarthritis. 2013 J. Dent. Res. pmid:23934157
Shao H et al. Intra-articular injection of xanthan gum reduces pain and cartilage damage in a rat osteoarthritis model. 2013 Carbohydr Polym pmid:23399228
Cialdai C et al. Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats. 2013 Eur. J. Pharmacol. pmid:23891968
Escobar-Hoyos LF et al. Genotoxic and clastogenic effects of monohaloacetic acid drinking water disinfection by-products in primary human lymphocytes. 2013 Water Res. pmid:23602619
Pals J et al. Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts. 2013 Environ. Sci. Technol. pmid:24050308
Dhaneshwar S and Patil D Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia. 2013 Med Chem pmid:22920092