Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Leukemia, Experimental D007942 42 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lymphoma D008223 18 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Muscle Cramp D009120 3 associated lipids
Nerve Degeneration D009410 53 associated lipids
Osteoarthritis D010003 4 associated lipids
Pain D010146 64 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Law RO Factors affecting the distribution of chloride ions in rat renal outer medulla. 1977 J. Physiol. (Lond.) pmid:856997
Thibert P and Nicolet M [Tetanic fatigue and proximate post-tetanic recuperation in sartorius and flexor carpi radialis muscles of the male frog. Effects of iodoacetic acid (author's transl)]. 1976 J. Physiol. (Paris) pmid:1083432
Lehner C et al. Nitric oxide suppresses growth and development in the unicellular green alga Micrasterias denticulata. 2009 J. Plant Physiol. pmid:18455833
Denton ME and Scheraga HA Spectroscopic, immunochemical, and thermodynamic properties of carboxymethyl(Cys6, Cys127)-hen egg white lysozyme. 1991 J. Protein Chem. pmid:1930635
Kohanski RA and Heinrikson RL Primary structure of avian hepatic rhodanese. 1990 J. Protein Chem. pmid:2275748
Batra PP et al. Circular dichroic study of conformational changes in ovalbumin induced by modification of sulfhydryl groups and disulfide reduction. 1989 J. Protein Chem. pmid:2610856
Wang H et al. Proteomic analysis of early-responsive redox-sensitive proteins in Arabidopsis. 2012 J. Proteome Res. pmid:22050424
Lin D et al. Cysteinyl peptide capture for shotgun proteomics: global assessment of chemoselective fractionation. 2010 J. Proteome Res. pmid:20731415
Lepley PR and Mukkada AJ Characteristics of an uptake system for alpha-aminoisobutyric acid in Leishmania tropica promastigotes. 1983 J. Protozool. pmid:6864594
Kalbhen DA Chemical model of osteoarthritis--a pharmacological evaluation. 1987 J. Rheumatol. pmid:3625668
Williams JM and Brandt KD Benoxaprofen reduces osteophyte formation and fibrillation after articular cartilage injury. 1985 J. Rheumatol. pmid:3981515
van Osch GJ et al. Site specific inhibition of cartilage proteoglycan synthesis in the murine knee joint. Differences between 3 metabolic stimuli. 1994 J. Rheumatol. pmid:7932423
Loeuille D et al. In vitro magnetic resonance microimaging of experimental osteoarthritis in the rat knee joint. 1997 J. Rheumatol. pmid:9002024
Yang R et al. Partial purification and characterisation of cysteine protease in wheat germ. 2011 J. Sci. Food Agric. pmid:21702054
Nagarathnam R et al. Purification and properties of cysteine protease from rhizomes of Curcuma longa (Linn.). 2010 J. Sci. Food Agric. pmid:20355018
Silva CM and Cidlowski JA The effect of oxidation/reduction on the charge heterogeneity of the human glucocorticoid receptor. 1992 J. Steroid Biochem. Mol. Biol. pmid:1734932
Kahlenberg A and Zala CA Reconstitution of D-glucose transport in vesicles composed of lipids and intrinsic protein (zone 4.5) of the human erythrocyte membrane. 1977 J. Supramol. Struct. pmid:616483
Phillips ER and Perdue JF The expression and localization of surface neoantigens in transformed and untransformed cultured cells infected with avian tumor viruses. 1976 J. Supramol. Struct. pmid:1256061
Bárány M et al. Structural changes in myosin during contraction and the state of ATP in the intact frog muscle. 1975 J. Supramol. Struct. pmid:127883
Matsuki N et al. Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia. 2002 J. Vet. Med. Sci. pmid:12014580
Kaneda T et al. Key role of glycogen storage in high K+-induced contraction of the smooth muscles of the bovine trachea. 2012 J. Vet. Med. Sci. pmid:22673054
Shangraw RE and Turinsky J Local response of muscle to burns: relationship of glycolysis and amino acid release. 1981 May-Jun JPEN J Parenter Enteral Nutr pmid:7195947
Narita H et al. Ischemia-reperfusion induced elevation of diastolic tension in the isolated guinea pig heart and the effects of calcium antagonists. 1983 Jpn Heart J pmid:6854962
Chhatwal GS and Gaitonde BB Purification of a nontoxic phospholipase A2 from the venom of Indian krait (Bungarus caeruleus). 1978 Jpn. J. Med. Sci. Biol. pmid:32414
Fukuda H and Kontani H Effects of metabolic inhibitors and ouabain on static afferent discharges from the isolated frog muscle spindle. 1976 Jpn. J. Pharmacol. pmid:1088168
Kishi M et al. Pharmacological characteristics of choline transport system in mouse cerebral cortical neurons in primary culture. 1991 Jpn. J. Pharmacol. pmid:2067141
Yamamoto K et al. Characteristics of activation of cathepsin B by sodium salicylate and comparison of catalytic site properties of cathepsins B and H. 1985 Jpn. J. Pharmacol. pmid:4087567
Nasu T et al. Role of glycolysis in the tension development under anoxia in guinea pig taenia coli. 1982 Jpn. J. Pharmacol. pmid:7087264
Sorimachi M and Nishimura S A small increment of external K concentration accelerates adrenomedullary catecholamine secretion induced by ouabain and metabolic inhibitors. 1983 Jpn. J. Physiol. pmid:6315998
Kuwata K et al. Cross-relaxation times of normal and biochemically induced osteoarthritic rabbit knee cartilages. 1997 Jpn. J. Physiol. pmid:9271160
Yoshizaki K et al. Intracellular pH measurement in frog muscle by means of 31P-nuclear magnetic resonance. 1979 Jpn. J. Physiol. pmid:40052
Somerville PJ and Kaye M Action of phosphorus on calcium release in isolated perfused rat tails. 1982 Kidney Int. pmid:6294399
KOHLER V and SCHARF J [Importance of metabolic processes sensitive to mono-iodoacetic acid for tissue inflammation]. 1951 Klin. Wochenschr. pmid:14825752
Choi MH et al. Purification of a 68-kDa cysteine proteinase from crude extract of Pneumocystis carinii. 2000 Korean J. Parasitol. pmid:11002651
Chung YB et al. Partial characterization of a 17 kDa protein of Clonorchis sinensis. 2000 Korean J. Parasitol. pmid:10905071
Kim JY et al. Partial characterization of a 29 kDa cysteine protease purified from Taenia solium metacestodes. 2005 Korean J. Parasitol. pmid:16340305
Lee SJ et al. Alterations in membrane transport function and cell viability induced by ATP depletion in primary cultured rabbit renal proximal tubular cells. 2009 Korean J. Physiol. Pharmacol. pmid:19885021
Noda K Possible mechanism for producing enhanced 45 Ca ion release from the muscle membrane in the presence of iodoacetate. 1971 Kurume Med J pmid:5211565
Phelps PC et al. Cytosolic ionized calcium and bleb formation after acute cell injury of cultured rabbit renal tubule cells. 1989 Lab. Invest. pmid:2654473
Cazenave JP et al. Effects of sodium periodate on platelet functions. 1976 Lab. Invest. pmid:178961
Rogers AB et al. Thiol-reactive compounds prevent nonspecific antibody binding in immunohistochemistry. 2006 Lab. Invest. pmid:16534499
Buja LM et al. Alterations of ultrastructure and elemental composition in cultured neonatal rat cardiac myocytes after metabolic inhibition with iodoacetic acid. 1985 Lab. Invest. pmid:2413276
McArthur W et al. Bone solubilization by mononuclear cells. 1980 Lab. Invest. pmid:7374109
Gill DS and Wickramasinghe SN Observations on the intracellular accumulation of methotrexate and 5-methyltetrahydrofolate in uninduced, dimethylsulphoxide-induced and 1,25-dihydroxyvitamin D3-induced HL60 cells, and blood-monocyte-derived human macrophages. 1988 Leuk. Res. pmid:2833665
Smit V In vitro suppression of leukemia by alkylated interleukin-3. 1995 Leukemia pmid:7769858
Kawanishi T et al. Suppression of Na+ influx in ATP-depleted hepatocytes. 1995 Life Sci. pmid:7603308
Bartha E et al. Molecular form of human lymphocyte membrane-bound acetylcholinesterase. 1987 Life Sci. pmid:3657387
Yang NC et al. ATP depletion is an important factor in DHEA-induced growth inhibition and apoptosis in BV-2 cells. 2002 Life Sci. pmid:12148690
Turkelson CM Effects of ATP synthesis inhibitors, temperature, 8-bromo c-AMP, and calcium omission on release of corticotropin releasing factor from superfused rat hypothalami. 1988 Life Sci. pmid:3262804
Kagawa S et al. Development and function of B cells in monolayer islet cells of 3-week-old rat. 1987 Life Sci. pmid:2444853