Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Rickets D012279 6 associated lipids
Retinitis D012173 4 associated lipids
Cumulative Trauma Disorders D012090 2 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Pain D010146 64 associated lipids
Osteoarthritis D010003 4 associated lipids
Nerve Degeneration D009410 53 associated lipids
Muscle Cramp D009120 3 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
ISSEKUTZ B et al. Tissue metabolism and peripheral circulation. I. Effect of iodoacetic acid on the metabolism of muscles "in vivo". 1951 Arch Int Physiol pmid:14857870
ISSEKUTZ B et al. Tissue metabolism and peripheral circulation. II. Effect of iodoacetic acid on peripheral circulation. 1951 Arch Int Physiol pmid:14857871
EBE M Effect of glutamic acid, NaCN and monoiodoacetic acid on the potential changes of isolated toad's brain. 1952 Tohoku J. Exp. Med. pmid:13005477
Ewart RB and Taylor KW The regulation of growth hormone secretion from the isolated rat anterior pituitary in vitro. The role of adenosine 3':5'-cyclic monophosphate. 1971 Biochem. J. pmid:4331962
Ochs S and Smith CB Fast axoplasmic transport in mammalian nerve in vitro after block of glycolysis with iodoacetic acid. 1971 J. Neurochem. pmid:4105449
Laiho KU et al. Observations on cell volume, ultrastructure, mitochondrial conformation and vital-dye uptake in Ehrlich ascites tumor cells. Effects of inhibiting energy production and function of the plasma membrane. 1971 Am. J. Pathol. pmid:5096366
Davey KJ and Skegg DC The effects of high concentrations of an electrolyte on the swelling of non-metabolizing tissue slices. 1971 J. Physiol. (Lond.) pmid:5557065
Robinson JR Control of water content of non-metabolizing kidney slices by sodium chloride and polyethylene glycol (PEG 6000). 1971 J. Physiol. (Lond.) pmid:5575341
McGrath JJ and Jaeger J Effect of iodoacetate on the carbon monoxide tolerance of the chick. 1971 Respir Physiol pmid:5578728
Godfraind JM et al. Actions of dinitrophenol and some other metabolic inhibitors on cortical neurones. 1971 J. Physiol. (Lond.) pmid:5579652
Boullin DJ and O'Brien RA Accumulation of quinidine by human blood platelets: effects on platelet ultrastructure and 5-hydroxytryptamine. 1971 Br. J. Pharmacol. pmid:5580696
Skelton CL et al. Mechanochemistry of cardiac muscle. V. Influence of thyroid state on energy utilization. 1971 J. Clin. Invest. pmid:5545115
Konings AW The influence of iodoacetate on the mechanism of nuclear glucose oxidation. 1971 Experientia pmid:5546629
Cohen AB and Cline MJ The human alveolar macrophage: isolation, cultivation in vitro, and studies of morphologic and functional characteristics. 1971 J. Clin. Invest. pmid:4996883
Podoler H and Applebaum SW The -amylase of the Beetle Callosobruchus chinensis. Properties. 1971 Biochem. J. pmid:5000646
Boughton WH et al. Metabolic factors affecting enhanced phosphorus uptake by activated sludge. 1971 Appl Microbiol pmid:5002140
Augusteyn RC and Spector A -Crystallin. Fractionation of subunits and sequence studies on an isolated polypeptide. 1971 Biochem. J. pmid:5158504
Corran PH and Waley SG Amino acid sequences around the cysteine residue of calf lens -crystallin. 1971 Biochem. J. pmid:5166593
Noda K Possible mechanism for producing enhanced 45 Ca ion release from the muscle membrane in the presence of iodoacetate. 1971 Kurume Med J pmid:5211565
Mudd JB et al. Inhibition of glycolipid biosynthesis in chloroplasts by ozone and sulfhydryl reagents. 1971 Plant Physiol. pmid:16657793