Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Mehrotra S et al. Mutational analysis of cysteine 328 and cysteine 368 at the interface of Plasmodium falciparum adenylosuccinate synthetase. 2012 Biochim. Biophys. Acta pmid:22289630
Sotelo-Hitschfeld T et al. Acute feedback control of astrocytic glycolysis by lactate. 2012 Glia pmid:22290492
Yu MK et al. Targeting strategies for multifunctional nanoparticles in cancer imaging and therapy. 2012 Theranostics pmid:22272217
Lunetta C et al. Impaired expression of insulin-like growth factor-1 system in skeletal muscle of amyotrophic lateral sclerosis patients. 2012 Muscle Nerve pmid:22246875
Xie L et al. Quantitative imaging of cartilage and bone morphology, reactive oxygen species, and vascularization in a rodent model of osteoarthritis. 2012 Arthritis Rheum. pmid:22231023
Izumi M et al. RBCS1A and RBCS3B, two major members within the Arabidopsis RBCS multigene family, function to yield sufficient Rubisco content for leaf photosynthetic capacity. 2012 J. Exp. Bot. pmid:22223809
North SJ et al. Glycomic analysis of human mast cells, eosinophils and basophils. 2012 Glycobiology pmid:21725073
Ashkavand Z et al. Silymarin potentiates the anti-inflammatory effects of Celecoxib on chemically induced osteoarthritis in rats. 2012 Phytomedicine pmid:22925727
Schuelert N and McDougall JJ Involvement of Nav 1.8 sodium ion channels in the transduction of mechanical pain in a rodent model of osteoarthritis. 2012 Arthritis Res. Ther. pmid:22225591
Shimada T et al. Development of iodoacetic acid-based cysteine mass tags: detection enhancement for cysteine-containing peptide by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. 2012 Anal. Biochem. pmid:22206935
Reyes-Fermín LM et al. Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death. 2012 Nutr Neurosci pmid:22776704
Wei X et al. Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells. 2013 Environ. Sci. Technol. pmid:23641915
Nan Y et al. Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat. 2013 Sci China Life Sci pmid:23657794
More AS et al. Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. 2013 Pharmacol. Biochem. Behav. pmid:23287799
La Porta C et al. Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate. 2013 Pain pmid:23199705
Song M et al. Monitoring of deiodinase deficiency based on transcriptomic responses in SH-SY5Y cells. 2013 Arch. Toxicol. pmid:23397585
Moon SJ et al. Augmented chondroprotective effect of coadministration of celecoxib and rebamipide in the monosodium iodoacetate rat model of osteoarthritis. 2013 Arch. Pharm. Res. pmid:23338062
Ogbonna AC et al. Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice. 2013 Eur J Pain pmid:23169679
Pals J et al. Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts. 2013 Environ. Sci. Technol. pmid:24050308
Liu X et al. An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water. 2013 PLoS ONE pmid:23613747