| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stroke | D020521 | 32 associated lipids |
| Starvation | D013217 | 47 associated lipids |
| Hypocalcemia | D006996 | 12 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Epilepsy | D004827 | 35 associated lipids |
| Nerve Degeneration | D009410 | 53 associated lipids |
| Leukemia, Experimental | D007942 | 42 associated lipids |
| Hyperalgesia | D006930 | 42 associated lipids |
| Thrombocytopenia | D013921 | 15 associated lipids |
| Hyperlipidemias | D006949 | 73 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Fushimi R et al. | [Effects of glycolysis inhibitor on the change of pyruvate concentration in blood in vitro (author's transl)]. | 1980 | Rinsho Byori | pmid:7241819 |
| Suganuma M et al. | [Trypan blue staining capacities of the culture cells (2)--The mechanism of staining]. | 1989 | Rinsho Byori | pmid:2482375 |
| Paradisi F et al. | Phagocytosis and cellular metabolism (a study on mouse and human macrophages in culture). | 1979 Jan-Mar | Ric Clin Lab | pmid:493813 |
| Kokan-Moore NP and Bergdoll MS | Determination of biologically active region in toxic shock syndrome toxin 1. | 1989 Jan-Feb | Rev. Infect. Dis. | pmid:2467343 |
| de la Fuente-Burguillo P and Nicolás G | Respiratory activity during germination of seeds of Cicer arietinum L. II. Effect of some metabolic inhibitors and mitochondrial activities. | 1979 | Rev. Esp. Fisiol. | pmid:542702 |
| Arlet J and Gédéon P | [Experimental arthrosis]. | 1982 | Rev Rhum Mal Osteoartic | pmid:7038833 |
| Xu YD et al. | The early asthmatic response is associated with glycolysis, calcium binding and mitochondria activity as revealed by proteomic analysis in rats. | 2010 | Respir. Res. | pmid:20691077 |
| McGrath JJ and Jaeger J | Effect of iodoacetate on the carbon monoxide tolerance of the chick. | 1971 | Respir Physiol | pmid:5578728 |
| Savineau JP et al. | Cellular mechanisms of hypoxia-induced contraction in human and rat pulmonary arteries. | 1995 | Respir Physiol | pmid:7777701 |
| Zhao W and Guénard H | Bronchial smooth muscle energetics: effect of iodoacetate and hypoxia. | 1994 | Respir Physiol | pmid:8059090 |
| Imberti R et al. | Synergism of cyclosporin A and phospholipase inhibitors in protection against lethal injury to rat hepatocytes from oxidant chemicals. | 1992 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:1462047 |
| Miyazaki K et al. | Toxicity and biotransformation of acetaminophen in rat hepatocytes (I). Uptake and release. | 1983 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:6844740 |
| Elferink JG | Chrysotile asbestos-induced cytotoxicity and calcium-dependent exocytosis in polymorphonuclear leukocytes. | 1989 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:2554437 |
| Gershbein LL and Dan TC | Coenzyme specificity in the glycolysis of intraocular fluids. | 1975 | Res. Commun. Chem. Pathol. Pharmacol. | pmid:235777 |
| Cifarelli A et al. | The influence of some metabolic inhibitors on phagocytic activity of mouse macrophages in vitro. | 1979 | Res Exp Med (Berl) | pmid:424658 |
| Bersinger NA et al. | Pregnancy-associated plasma protein A (PAPP-A): measurement by highly sensitive and specific enzyme immunoassay, importance of first-trimester serum determinations, and stability studies. | 1995 | Reprod. Fertil. Dev. | pmid:8743141 |
| Abdo MA et al. | Inhibitors of caspase homologues suppress an apoptotic phenotype in cultured rabbit corpora lutea. | 2001 | Reprod. Fertil. Dev. | pmid:11833936 |
| Whitaker BD and Knight JW | Mechanisms of oxidative stress in porcine oocytes and the role of anti-oxidants. | 2008 | Reprod. Fertil. Dev. | pmid:18671917 |
| Chapman JC et al. | Mitochondrial 3 beta-hydroxysteroid dehydrogenase (HSD) is essential for the synthesis of progesterone by corpora lutea: an hypothesis. | 2005 | Reprod. Biol. Endocrinol. | pmid:15804366 |
| ten Kate RW et al. | Handling of human pepsinogens by the isolated rat kidney: evidence for a high glomerular sieving coefficient. | 1989 Jan-Feb | Ren. Physiol. Biochem. | pmid:2727383 |
| Hwang IS et al. | Investigation of sulfhydryl groups in cabbage phospholipase D by combination of derivatization methods and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | 2001 | Rapid Commun. Mass Spectrom. | pmid:11180538 |
| Lau BP and Becalski A | Determination of iodoacetic acid using liquid chromatography/electrospray tandem mass spectrometry. | 2008 | Rapid Commun. Mass Spectrom. | pmid:18470871 |
| Dmitriev AP and GrodzinskiÄ DM | [Effect of radiosensitizer (monoiodoacetate) on the recovery of sublethally damaged cells of blue-green alga, Anacystis nidulans]. | 1974 May-Jun | Radiobiologiia | pmid:4211026 |
| Mohyuddin M and Skoropad WP | Modification of the radiation resistance of Aspergillus flavus mycelial units by some chemicals. | 1977 | Radiat Environ Biophys | pmid:405704 |
| Seymour CB and Mothersill C | The effect of glycolysis inhibitors on the radiation response of CHO-K1 cells. | 1988 | Radiat Environ Biophys | pmid:3353494 |
| Ebeigbe AB et al. | Responses of systemic vascular smooth muscle to hypoxia. | 1980 | Q J Exp Physiol Cogn Med Sci | pmid:6906037 |
| Law RO | The influence of age on fluid and sodium chloride distribution in rat aortic wall. | 1984 | Q J Exp Physiol | pmid:6393187 |
| Ford AP | In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization. | 2012 | Purinergic Signal. | pmid:22095157 |
| Mann K et al. | Phosphoproteomes of Strongylocentrotus purpuratus shell and tooth matrix: identification of a major acidic sea urchin tooth phosphoprotein, phosphodontin. | 2010 | Proteome Sci | pmid:20181113 |
| Li SC et al. | Chicken model of steroid-induced bone marrow adipogenesis using proteome analysis: a preliminary study. | 2010 | Proteome Sci | pmid:20840762 |
| Kinsland C et al. | Overexpression of recombinant proteins with a C-terminal thiocarboxylate: implications for protein semisynthesis and thiamin biosynthesis. | 1998 | Protein Sci. | pmid:10082383 |
| Hruz PW and Miziorko HM | Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines. | 1992 | Protein Sci. | pmid:1304393 |
| Helms LR and Wetzel R | Proteolytic excision and in situ cyclization of a bioactive loop from an REI-VL presentation scaffold. | 1994 | Protein Sci. | pmid:7920257 |
| Peretz M et al. | Cysteine reactivity in Thermoanaerobacter brockii alcohol dehydrogenase. | 1997 | Protein Sci. | pmid:9144779 |
| Wang XY et al. | Kinetics of inactivation of phytase (phy A) during modification of histidine residue by IAA and DEP. | 2006 | Protein Pept. Lett. | pmid:16842110 |
| Pasqualini ME et al. | COX and LOX eicosanoids modulate platelet activation and procoagulation induced by two murine cancer cells. | 2000 | Prostaglandins Leukot. Essent. Fatty Acids | pmid:11133175 |
| Lehmann A et al. | In vivo regulation of extracellular taurine and other neuroactive amino acids in the rabbit hippocampus. | 1985 | Prog. Clin. Biol. Res. | pmid:2865739 |
| Bosron WF et al. | Purification and characterization of human liver beta 1 beta 1, beta 2 beta 2 and beta Ind beta Ind alcohol dehydrogenase isoenzymes. | 1985 | Prog. Clin. Biol. Res. | pmid:3885259 |
| Hersey SJ and Miller M | Metabolic properties of gastric glands. | 1981 | Prog. Clin. Biol. Res. | pmid:7323081 |
| Kempski O et al. | Swelling of C6 glioma cells and astrocytes from glutamate, high K+ concentrations or acidosis. | 1992 | Prog. Brain Res. | pmid:1363149 |
| Rosin DL et al. | A cysteine metalloproteinase from mouse liver cytosol. | 1984 | Proc. Soc. Exp. Biol. Med. | pmid:6433352 |
| GLASS GB et al. | Thermal coagulation point and iodoacetate index as detectors of abnormal serum proteins and underlying illness. | 1951 | Proc. Soc. Exp. Biol. Med. | pmid:14816377 |
| Ayala E and Canonico PG | Aminoisobutyric acid transport in primary cultures of normal adult rat hepatocytes. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:1166067 |
| Yip YK et al. | Studies on catalytic properties of purified high molecular weight pancreatic lipase. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:1144458 |
| Poole DT et al. | Rabbit muscle triosephosphate isomerase: activity and inactivation by sulfhydryl reagents as affected by enzyme concentration. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:1129283 |
| SANDOW A and BRUST M | Effect of activity on the visco-elasticity of normal and iodoacetate muscles. | 1946 | Proc. Soc. Exp. Biol. Med. | pmid:20277787 |
| Tosco M et al. | Ouabain-insensitive transintestinal transport in the rat jejunum incubated in vitro. | 1988 | Proc. Soc. Exp. Biol. Med. | pmid:2453889 |
| Denu JM and Dixon JE | A catalytic mechanism for the dual-specific phosphatases. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7597052 |
| Clusin WT | Mechanism by which metabolic inhibitors depolarize cultured cardiac cells. | 1983 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6574520 |
| Persson C et al. | Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:14762163 |