Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Sagar DR et al. The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain. 2011 Mol Pain pmid:22093915
Horisaki T et al. Isolation and characterization of monochloroacetic acid-degrading bacteria. 2011 J. Gen. Appl. Microbiol. pmid:22139456
Sacks DB et al. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. 2011 Diabetes Care pmid:21617108
Chen Q et al. A novel neurotrophic drug for cognitive enhancement and Alzheimer's disease. 2011 PLoS ONE pmid:22194796
Mohan G et al. Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis. 2011 Arthritis Res. Ther. pmid:22185204
Lee M et al. Direct sensing of endothelial oxidants by vascular endothelial growth factor receptor-2 and c-Src. 2011 PLoS ONE pmid:22145046
Potera C Nontoxic medical imaging agents form toxic DBPs. 2011 Environ. Health Perspect. pmid:22134135
Dosio F et al. Immunotoxins and anticancer drug conjugate assemblies: the role of the linkage between components. 2011 Toxins (Basel) pmid:22069744
Kim JS et al. The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain. 2011 Arthritis Res. Ther. pmid:21996269
Shen Y et al. Effect of Guanabenz on Rat AMD Models and Rabbit Choroidal Blood Flow. 2011 Open Ophthalmol J pmid:21633720
Valdes AM et al. The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis. 2011 Ann. Rheum. Dis. pmid:21616913
Palaniappan KK et al. Isotopic signature transfer and mass pattern prediction (IsoStamp): an enabling technique for chemically-directed proteomics. 2011 ACS Chem. Biol. pmid:21604797
Lee Y et al. Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord. 2011 Mol Pain pmid:21599960
Gozal YM et al. Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology. 2011 Front Neurol pmid:21577247
Seo MK et al. Repeated gene transfection impairs the engraftment of transplanted porcine neonatal pancreatic cells. 2011 Diabetes Metab J pmid:21537416
Ahn K et al. Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain. 2011 J. Pharmacol. Exp. Ther. pmid:21505060
Gong K et al. Rat model of lumbar facet joint osteoarthritis associated with facet-mediated mechanical hyperalgesia induced by intra-articular injection of monosodium iodoacetate. 2011 J. Formos. Med. Assoc. pmid:21497277
Zhou L et al. Differentiation of induced pluripotent stem cells of swine into rod photoreceptors and their integration into the retina. 2011 Stem Cells pmid:21491544
Kodali VK et al. A novel disulfide-rich protein motif from avian eggshell membranes. 2011 PLoS ONE pmid:21479176
Stevenson GW et al. Monosodium iodoacetate-induced osteoarthritis produces pain-depressed wheel running in rats: implications for preclinical behavioral assessment of chronic pain. 2011 Pharmacol. Biochem. Behav. pmid:21147151