Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Rickets D012279 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Byssinosis D002095 11 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Blindness D001766 6 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Wang YC et al. Intracellular Na(+) and metabolic modulation of Na/K pump and excitability in the rat suprachiasmatic nucleus neurons. 2012 J. Neurophysiol. pmid:22773774
Wang XD et al. Progression of cartilage degradation, bone resorption and pain in rat temporomandibular joint osteoarthritis induced by injection of iodoacetate. 2012 PLoS ONE pmid:22984604
Lee JH et al. Alteration patterns of trabecular bone microarchitectural characteristics induced by osteoarthritis over time. 2012 Clin Interv Aging pmid:22956865
Moon SJ et al. Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes. 2012 Osteoarthr. Cartil. pmid:22890185
Vincent A et al. parkin-induced defects in neurophysiology and locomotion are generated by metabolic dysfunction and not oxidative stress. 2012 Hum. Mol. Genet. pmid:22215442
Noel JM et al. Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage. 2012 Exp. Eye Res. pmid:22251455
Hardes K et al. Design, synthesis, and characterization of chromogenic substrates of coagulation factor XIIIa. 2012 Anal. Biochem. pmid:22683584
Rao Y et al. Mapping of sulfur metabolic pathway by LC Orbitrap mass spectrometry. 2012 Anal. Chim. Acta pmid:22405311
Sagar DR et al. The contribution of spinal glial cells to chronic pain behaviour in the monosodium iodoacetate model of osteoarthritic pain. 2011 Mol Pain pmid:22093915
Dosio F et al. Immunotoxins and anticancer drug conjugate assemblies: the role of the linkage between components. 2011 Toxins (Basel) pmid:22069744
Kim JS et al. The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain. 2011 Arthritis Res. Ther. pmid:21996269
Edwards TE et al. Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis. 2011 BMC Struct. Biol. pmid:21995815
Gozal YM et al. Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology. 2011 Front Neurol pmid:21577247
Seo MK et al. Repeated gene transfection impairs the engraftment of transplanted porcine neonatal pancreatic cells. 2011 Diabetes Metab J pmid:21537416
Ahn K et al. Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain. 2011 J. Pharmacol. Exp. Ther. pmid:21505060
Gong K et al. Rat model of lumbar facet joint osteoarthritis associated with facet-mediated mechanical hyperalgesia induced by intra-articular injection of monosodium iodoacetate. 2011 J. Formos. Med. Assoc. pmid:21497277
Zhou L et al. Differentiation of induced pluripotent stem cells of swine into rod photoreceptors and their integration into the retina. 2011 Stem Cells pmid:21491544
Kodali VK et al. A novel disulfide-rich protein motif from avian eggshell membranes. 2011 PLoS ONE pmid:21479176
Breeze E et al. High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. 2011 Plant Cell pmid:21447789
Zilliges Y et al. The cyanobacterial hepatotoxin microcystin binds to proteins and increases the fitness of microcystis under oxidative stress conditions. 2011 PLoS ONE pmid:21445264