Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Rickets D012279 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Byssinosis D002095 11 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Blindness D001766 6 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Rogers AB et al. Thiol-reactive compounds prevent nonspecific antibody binding in immunohistochemistry. 2006 Lab. Invest. pmid:16534499
Buja LM et al. Alterations of ultrastructure and elemental composition in cultured neonatal rat cardiac myocytes after metabolic inhibition with iodoacetic acid. 1985 Lab. Invest. pmid:2413276
Noda K Possible mechanism for producing enhanced 45 Ca ion release from the muscle membrane in the presence of iodoacetate. 1971 Kurume Med J pmid:5211565
Lee SJ et al. Alterations in membrane transport function and cell viability induced by ATP depletion in primary cultured rabbit renal proximal tubular cells. 2009 Korean J. Physiol. Pharmacol. pmid:19885021
Choi MH et al. Purification of a 68-kDa cysteine proteinase from crude extract of Pneumocystis carinii. 2000 Korean J. Parasitol. pmid:11002651
Chung YB et al. Partial characterization of a 17 kDa protein of Clonorchis sinensis. 2000 Korean J. Parasitol. pmid:10905071
Kim JY et al. Partial characterization of a 29 kDa cysteine protease purified from Taenia solium metacestodes. 2005 Korean J. Parasitol. pmid:16340305
KOHLER V and SCHARF J [Importance of metabolic processes sensitive to mono-iodoacetic acid for tissue inflammation]. 1951 Klin. Wochenschr. pmid:14825752
Somerville PJ and Kaye M Action of phosphorus on calcium release in isolated perfused rat tails. 1982 Kidney Int. pmid:6294399
Sorimachi M and Nishimura S A small increment of external K concentration accelerates adrenomedullary catecholamine secretion induced by ouabain and metabolic inhibitors. 1983 Jpn. J. Physiol. pmid:6315998
Kuwata K et al. Cross-relaxation times of normal and biochemically induced osteoarthritic rabbit knee cartilages. 1997 Jpn. J. Physiol. pmid:9271160
Yoshizaki K et al. Intracellular pH measurement in frog muscle by means of 31P-nuclear magnetic resonance. 1979 Jpn. J. Physiol. pmid:40052
Fukuda H and Kontani H Effects of metabolic inhibitors and ouabain on static afferent discharges from the isolated frog muscle spindle. 1976 Jpn. J. Pharmacol. pmid:1088168
Kishi M et al. Pharmacological characteristics of choline transport system in mouse cerebral cortical neurons in primary culture. 1991 Jpn. J. Pharmacol. pmid:2067141
Yamamoto K et al. Characteristics of activation of cathepsin B by sodium salicylate and comparison of catalytic site properties of cathepsins B and H. 1985 Jpn. J. Pharmacol. pmid:4087567
Nasu T et al. Role of glycolysis in the tension development under anoxia in guinea pig taenia coli. 1982 Jpn. J. Pharmacol. pmid:7087264
Chhatwal GS and Gaitonde BB Purification of a nontoxic phospholipase A2 from the venom of Indian krait (Bungarus caeruleus). 1978 Jpn. J. Med. Sci. Biol. pmid:32414
Narita H et al. Ischemia-reperfusion induced elevation of diastolic tension in the isolated guinea pig heart and the effects of calcium antagonists. 1983 Jpn Heart J pmid:6854962
Shangraw RE and Turinsky J Local response of muscle to burns: relationship of glycolysis and amino acid release. 1981 May-Jun JPEN J Parenter Enteral Nutr pmid:7195947
Matsuki N et al. Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia. 2002 J. Vet. Med. Sci. pmid:12014580
Kaneda T et al. Key role of glycogen storage in high K+-induced contraction of the smooth muscles of the bovine trachea. 2012 J. Vet. Med. Sci. pmid:22673054
Kahlenberg A and Zala CA Reconstitution of D-glucose transport in vesicles composed of lipids and intrinsic protein (zone 4.5) of the human erythrocyte membrane. 1977 J. Supramol. Struct. pmid:616483
Phillips ER and Perdue JF The expression and localization of surface neoantigens in transformed and untransformed cultured cells infected with avian tumor viruses. 1976 J. Supramol. Struct. pmid:1256061
Bárány M et al. Structural changes in myosin during contraction and the state of ATP in the intact frog muscle. 1975 J. Supramol. Struct. pmid:127883
Silva CM and Cidlowski JA The effect of oxidation/reduction on the charge heterogeneity of the human glucocorticoid receptor. 1992 J. Steroid Biochem. Mol. Biol. pmid:1734932
Yang R et al. Partial purification and characterisation of cysteine protease in wheat germ. 2011 J. Sci. Food Agric. pmid:21702054
Nagarathnam R et al. Purification and properties of cysteine protease from rhizomes of Curcuma longa (Linn.). 2010 J. Sci. Food Agric. pmid:20355018
Kalbhen DA Chemical model of osteoarthritis--a pharmacological evaluation. 1987 J. Rheumatol. pmid:3625668
Williams JM and Brandt KD Benoxaprofen reduces osteophyte formation and fibrillation after articular cartilage injury. 1985 J. Rheumatol. pmid:3981515
van Osch GJ et al. Site specific inhibition of cartilage proteoglycan synthesis in the murine knee joint. Differences between 3 metabolic stimuli. 1994 J. Rheumatol. pmid:7932423
Loeuille D et al. In vitro magnetic resonance microimaging of experimental osteoarthritis in the rat knee joint. 1997 J. Rheumatol. pmid:9002024
Lepley PR and Mukkada AJ Characteristics of an uptake system for alpha-aminoisobutyric acid in Leishmania tropica promastigotes. 1983 J. Protozool. pmid:6864594
Wang H et al. Proteomic analysis of early-responsive redox-sensitive proteins in Arabidopsis. 2012 J. Proteome Res. pmid:22050424
Lin D et al. Cysteinyl peptide capture for shotgun proteomics: global assessment of chemoselective fractionation. 2010 J. Proteome Res. pmid:20731415
Denton ME and Scheraga HA Spectroscopic, immunochemical, and thermodynamic properties of carboxymethyl(Cys6, Cys127)-hen egg white lysozyme. 1991 J. Protein Chem. pmid:1930635
Kohanski RA and Heinrikson RL Primary structure of avian hepatic rhodanese. 1990 J. Protein Chem. pmid:2275748
Batra PP et al. Circular dichroic study of conformational changes in ovalbumin induced by modification of sulfhydryl groups and disulfide reduction. 1989 J. Protein Chem. pmid:2610856
Lehner C et al. Nitric oxide suppresses growth and development in the unicellular green alga Micrasterias denticulata. 2009 J. Plant Physiol. pmid:18455833
Thibert P and Nicolet M [Tetanic fatigue and proximate post-tetanic recuperation in sartorius and flexor carpi radialis muscles of the male frog. Effects of iodoacetic acid (author's transl)]. 1976 J. Physiol. (Paris) pmid:1083432
Blaustein MP and Goldring JM Membrane potentials in pinched-off presynaptic nerve ternimals monitored with a fluorescent probe: evidence that synaptosomes have potassium diffusion potentials. 1975 J. Physiol. (Lond.) pmid:49421
McIver DJ and Raine AE The influence of electrolytes on the volume of non-metabolizing renal cortical cells. 1972 J. Physiol. (Lond.) pmid:5076387
Hess P et al. Free magnesium in sheep, ferret and frog striated muscle at rest measured with ion-selective micro-electrodes. 1982 J. Physiol. (Lond.) pmid:6820662
Bountra C et al. Mechanism of rate-dependent pH changes in the sheep cardiac Purkinje fibre. 1988 J. Physiol. (Lond.) pmid:3254421
Brading AF Calcium-induced increase in membrane permeability in the guinea-pig taenia coli: evidence for involvement of a sodium-calcium exchange mechanism. 1978 J. Physiol. (Lond.) pmid:633162
Kito Y and Suzuki H Pacemaker frequency is increased by sodium nitroprusside in the guinea pig gastric antrum. 2003 J. Physiol. (Lond.) pmid:12509488
Law RO Factors affecting the distribution of chloride ions in rat renal outer medulla. 1977 J. Physiol. (Lond.) pmid:856997
Wray S The effects of metabolic inhibition on uterine metabolism and intracellular pH in the rat. 1990 J. Physiol. (Lond.) pmid:2388156
Duchen MR Effects of metabolic inhibition on the membrane properties of isolated mouse primary sensory neurones. 1990 J. Physiol. (Lond.) pmid:2391654
Allen DG et al. Metabolic consequences of increasing intracellular calcium and force production in perfused ferret hearts. 1986 J. Physiol. (Lond.) pmid:3795073
Westerblad H and Lännergren J Reduced maximum shortening velocity in the absence of phosphocreatine observed in intact fibres of Xenopus skeletal muscle. 1995 J. Physiol. (Lond.) pmid:7714829