Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Rickets D012279 6 associated lipids
Blood Platelet Disorders D001791 12 associated lipids
Byssinosis D002095 11 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Vitamin D Deficiency D014808 13 associated lipids
Vascular Diseases D014652 16 associated lipids
Photosensitivity Disorders D010787 8 associated lipids
Thymus Neoplasms D013953 15 associated lipids
Blindness D001766 6 associated lipids
Vitamin B 6 Deficiency D026681 10 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Stewart GR and Stevenson KJ The isolation and partial characterization of ribonuclease A from Bison bison. 1973 Biochem. J. pmid:4772270
Canfield P et al. Energy balance in frog sartorius muscle during an isometric tetanus at 20 degrees C. 1973 J. Physiol. (Lond.) pmid:4759678
Poole B and Wibo M Protein degradation in cultured cells. The effect of fresh medium, fluoride, and iodoacetate on the digestion of cellular protein of rat fibroblasts. 1973 J. Biol. Chem. pmid:4737734
Bryce CF and Crichton RR The catalytic activity of horse spleen apoferritin. Preliminary kinetic studies and the effect of chemical modification. 1973 Biochem. J. pmid:4737426
Bradbury AF and Smyth DG The use of 3-bromopropionic acid for the determination of protein thiol groups. 1973 Biochem. J. pmid:4737322
Hwang UK and Connors NA The effect of iodoacetate on the developing chick metanephros. 1973 Experientia pmid:4729463
Miller TJ Cleft palate formation: the effects of fasting and iodoacetic acid on mice. 1973 Teratology pmid:4725547
Harada M and Irie M Alkylation of ribonuclease from Aspergillus saitoi with iodoacetate and iodoacetamide. 1973 J. Biochem. pmid:4720055
Ling GN and Ochsenfeld MM Mobility of potassium ion in frog muscle cells, both living and dead. 1973 Science pmid:4714293
Bowman RH et al. Furosemide, ethacrynic acid, and iodoacetate on function and metabolism in perfused rat kidney. 1973 Am. J. Physiol. pmid:4686497
Bridgen J The reactivity and function of thiol groups in trout actin. 1972 Biochem. J. pmid:4672661
Meites S and Saniel-Banrey K Preservation, distribution, and assay of glucose in blood, with special reference to the newborn. 1979 Clin. Chem. pmid:466761
Brownson C and Spencer N Partial purification and properties of the two common inherited forms of human erythrocyte adenylate kinase. 1972 Biochem. J. pmid:4664934
Younis AE et al. Respiratory metabolism of Fusarium oxysporum fed with alanine in presence and absence of iodoacetate. 1972 Acta Biol Acad Sci Hung pmid:4661859
Pautler EL et al. The effect of iodoacetate on the retinal cell DNA in rabbit. 1972 Exp. Eye Res. pmid:4640865
Lee CY et al. Purification and characterization of mouse glucose 6-phosphate dehydrogenase. 1979 Mol. Cell. Biochem. pmid:460173
Barker AD et al. Immunologic responsiveness of young AKR mice to iodoacetate and to iodoacetate-treated tumor cells. 1973 Immunol. Commun. pmid:4583065
Rheins MS and Barker AD Therapeutic and immunologic effects of iodoacetate in mature AKR mice. 1973 Experientia pmid:4575260
Canfield P and Maréchal G Equilibrium of nucleotides in frog sartorius muscle during an isometric tetanus at 20 degrees C. 1973 J. Physiol. (Lond.) pmid:4543341
Malcolm GB et al. Biochemical and serological characteristics of soluble yeast phase antigens of Histoplasma capsulatum. 1979 Mycopathologia pmid:450035
Cooke RD and Holbrook JJ The calcium-induced dissociation of human plasma clotting factor XIII. 1974 Biochem. J. pmid:4477004
Cooke RD et al. Calcium and thiol reactivity of human plasma clotting factor XIII. 1974 Biochem. J. pmid:4463957
Ahtee L et al. Transport of taurine by normal human blood platelets. 1974 Br. J. Pharmacol. pmid:4451820
Kaufmann P et al. [The morphology of the guinea pig placenta after poisoning with monoiodineacetate and fluoride (author's transl)]. 1974 Arch Gynakol pmid:4406634
Thorn W et al. [Carbohydrate turn over, energy deficit and the formation of plasma polyps within the placenta after poisoning with monoiodineacetate and sodium fluoride (author's transl)]. 1974 Arch Gynakol pmid:4406633
Sabri MI and Ochs S Inhibition of glyceraldehyde-3-phosphate dehydrogenase in mammalian nerve by iodoacetic acid. 1971 J. Neurochem. pmid:4398402
Odorzynski TW and Light A Refolding of the mixed disulfide of bovine trypsinogen and glutathione. 1979 J. Biol. Chem. pmid:438188
Serrano R and Reeves RE Glucose transport in Entamoeba histolytica. 1974 Biochem. J. pmid:4376956
Tomioka H et al. [The difference of drug sensitivity of tumor cells on N-ethyloxycarbonylaminomethyl-L-isoleucine (A-145 (author's transl)]. 1979 Nippon Yakurigaku Zasshi pmid:437584
Monboisse JC et al. [Purification and physico-chemical properties of collagenase synthesized by a bacterium of the type Acinetobacter sp]. 1979 Biochimie pmid:43744
Jeck R et al. Identification of the amino acid residue modified in Bacillus stearothermophilus alcohol dehydrogenase by the NAD+ analogue 4-(3-bromoacetylpyridinio)butyldiphosphoadenosine. 1979 Eur. J. Biochem. pmid:436831
Jørgensen J Inactivation of renin in a mixed mitochondrial-lysosomal fraction of post-partum uterus. 1979 Acta Endocrinol. pmid:43645
Crawhall JC and Purkiss P Transport of methionine and proline by rat liver slices and the effect of certain hormones. 1973 Biochem. J. pmid:4359105
Alhadeff JA and Andrews-Smith GL Subunit composition of human liver alpha-L-fucosidase. 1979 Biochem. J. pmid:435266
Price NC The reaction of rabbit muscle creatine kinase with some derivatives of iodoacetamide. 1979 Biochem. J. pmid:435254
Fitton JE and Shaw WV Comparison of chloramphenicol acetyltransferase variants in staphylococci. Purification, inhibitor studies and N-terminal sequences. 1979 Biochem. J. pmid:435253
Carne T et al. The binding and catalytic activities of forms of ligandin after modification of its thiol groups. 1979 Biochem. J. pmid:435243
Hawkins HK et al. Lysosome and phagosome stability in lethal cell injury. Morphologic tracer studies in cell injury due to inhibition of energy metabolism, immune cytolysis and photosensitization. 1972 Am. J. Pathol. pmid:4340333
Godfraind-de Becker A Heat production and fluorescence changes of toad sartorius muscle during aerobic recovery after a short tetanus. 1972 J. Physiol. (Lond.) pmid:4339903
Ewart RB and Taylor KW The regulation of growth hormone secretion from the isolated rat anterior pituitary in vitro. The role of adenosine 3':5'-cyclic monophosphate. 1971 Biochem. J. pmid:4331962
Svasti J and Talupphet N Improvement in the resolution of human sperm protamines by use of iodoacetamide as alkylating agent. 1979 Biochim. Biophys. Acta pmid:427214
Mihashi K Alkylation of urea-denatured actin with iodoacetate: functional reorganization of actin. 1972 Biochim. Biophys. Acta pmid:4261330
Cifarelli A et al. The influence of some metabolic inhibitors on phagocytic activity of mouse macrophages in vitro. 1979 Res Exp Med (Berl) pmid:424658
Minato S and Hirai A Characterization of Ustilago Ribonuclease U2. Effects of chemical modification at glutamic acid-61 and cystine-1 and of organic solvents on the enzymatic activity. 1979 J. Biochem. pmid:422534
Fischbarg J and Lim JJ Role of cations, anions and carbonic anhydrase in fluid transport across rabbit corneal endothelium. 1974 J. Physiol. (Lond.) pmid:4215880
Dmitriev AP and GrodzinskiÄ­ DM [Effect of radiosensitizer (monoiodoacetate) on the recovery of sublethally damaged cells of blue-green alga, Anacystis nidulans]. 1974 May-Jun Radiobiologiia pmid:4211026
Huber RE and Mathison RD Physical, chemical, and enzymatic studies on the major sucrase of honey bees (Apis mellifera). 1976 Can. J. Biochem. pmid:4203
Sjöholm I and Ljungdahl M Protein A from Staphylococcus aureus. XVI. Alkylation with iodoacetic acid at different pH-values. 1973 Immunochemistry pmid:4200118
Starkey PM and Barrett AJ Inhibition by alpha-macroglobulin and other serum proteins. 1973 Biochem. J. pmid:4198623
Ogawa H and Fujioka M Purification and characterization of saccharopine dehydrogenase from baker's yeast. 1978 J. Biol. Chem. pmid:418069
Campbell IC and Todrick A On the pharmacology and biochemistry of the amine-uptake mechanism in human blood platelets. 1973 Br. J. Pharmacol. pmid:4152219
Hasilik A Perturbation of growth and metabolism in Candida albicans by 4-bromobenzyl isothiocyanate and iodoacetate. 1973 Jan-Feb Z Naturforsch C pmid:4148805
Mauck L and Colman RF Alkylation of cysteinyl residues of pig heart NAD-specific isocitrate dehydrogenase by iodoacetate. 1976 Biochim. Biophys. Acta pmid:4125
Garcia AG and Kirpekar SM Release of noradrenaline from the cat spleen by sodium deprivation. 1973 Br. J. Pharmacol. pmid:4124979
Kirpekar SM et al. Metabolic and ionic requirements for the intra-axonal transport of noradrenaline in the cat hypogastric nerve. 1973 J. Physiol. (Lond.) pmid:4119622
DiPolo R and Caputo C The effect of ATP on calcium efflux in dialyzed barnacle muscle fibres. 1977 Biochim. Biophys. Acta pmid:411508
Flagg-Newton J and Loewenstein WR Experimental depression of junctional membrane permeability in mammalian cell culture. A study with tracer molecules in the 300 to 800 Dalton range. 1979 J. Membr. Biol. pmid:41101
Ochs S and Smith CB Fast axoplasmic transport in mammalian nerve in vitro after block of glycolysis with iodoacetic acid. 1971 J. Neurochem. pmid:4105449
Yamamoto K et al. Characteristics of activation of cathepsin B by sodium salicylate and comparison of catalytic site properties of cathepsins B and H. 1985 Jpn. J. Pharmacol. pmid:4087567
Ashiba G and Szent-Györgyi AG Essential light chain exchange in scallop myosin. 1985 Biochemistry pmid:4084545
Beyer WF and Fridovich I Pseudocatalase from Lactobacillus plantarum: evidence for a homopentameric structure containing two atoms of manganese per subunit. 1985 Biochemistry pmid:4084532
Wakade AR and Wakade TD Sympathetic neurons grown in culture generate ATP by glycolysis: correlation between ATP content and [3H]norepinephrine uptake and storage. 1985 Brain Res. pmid:4075161
Williams JM and Brandt KD Triamcinolone hexacetonide protects against fibrillation and osteophyte formation following chemically induced articular cartilage damage. 1985 Arthritis Rheum. pmid:4063001
Buchmann U and Kalbhen DA [Experimental gonarthrosis in rats and its therapy with glycosaminoglycan polysulfate (GAGPS)]. 1985 May-Jun Z Rheumatol pmid:4060902
Mitchell DB et al. Role of glutathione depletion in the cytotoxicity of acetaminophen in a primary culture system of rat hepatocytes. 1985 Toxicology pmid:4060164
Gibson DD et al. GSH-dependent inhibition of lipid peroxidation: properties of a potent cytosolic system which protects cell membranes. 1985 Lipids pmid:4058268
Mohyuddin M and Skoropad WP Modification of the radiation resistance of Aspergillus flavus mycelial units by some chemicals. 1977 Radiat Environ Biophys pmid:405704
Kalbhen DA [Orienting animal experiment studies on the effect of fenbufen on healthy and arthrosis-induced articular cartilage tissue in vivo]. 1985 Jul-Aug Z Rheumatol pmid:4050149
Cox CP and Quissell DO A novel platelet-activating protein derived from rat submandibular glands. 1985 Thromb. Res. pmid:4049321
Clegg JS and Gordon EP Respiratory metabolism of L-929 cells at different water contents and volumes. 1985 J. Cell. Physiol. pmid:4044656
Parmelee JT et al. Effects of calcium on the steady outward currents at the equator of the rat lens. 1985 Invest. Ophthalmol. Vis. Sci. pmid:4044162
Milner MJ and Sang JH Active ion transport and beta-acdysone induced differentiation of Drosophila melanogaster imaginal discs cultured in vitro. 1977 J Embryol Exp Morphol pmid:404384
Gasanov GG et al. [Oscillatory evoked potentials in the rabbit visual system during experimental retinal pathology induced by administration of monoiodoacetic acid]. 1985 Biull Eksp Biol Med pmid:4041592
Khowala S and Sengupta S Purification and properties of an endo-alpha-mannan hydrolase from the mushroom Volvariella volvacea. 1985 Arch. Biochem. Biophys. pmid:4041163
Luchnik NV et al. [Effect of cell respiration inhibitors on the formation of structural mutations in human lymphocytes irradiated at different stages of the mitotic cycle]. 1985 Genetika pmid:4039281
Hatcher VB et al. Purification, properties, and partial structure elucidation of a high-molecular-weight glycoprotein from cervical mucus of the bonnet monkey (Macaca radiata). 1977 Biochemistry pmid:402940
Pliszka B and Lu RC Reactivities of thiols in myosin rod: effect of magnesium and ionic strength. 1985 Biochim. Biophys. Acta pmid:4027253
Yeramian E et al. N-ethylmaleimide-induced changes in agonist affinity for histamine H1-receptors in the guinea pig brain. 1985 Mol. Pharmacol. pmid:4022000
Estrada P et al. Mechanism of the reaction catalyzed by acyl-CoA: lysolecithin acyltransferase from rabbit lung. pH studies and chemical modification. 1985 Int. J. Pept. Protein Res. pmid:4019033
Donadio S et al. Alkylation of amide linkages and cleavage of the C chain in the enzyme-activated-substrate inhibition of alpha-chymotrypsin with N-nitrosamides. 1985 Biochemistry pmid:4016069
Busselen P Suppression of cellular injury during the calcium paradox in rat heart by factors which reduce calcium uptake by mitochondria. 1985 Pflugers Arch. pmid:4011406
Rispens P et al. Inhibition of carbonic anhydrase in dog plasma. 1985 Pflugers Arch. pmid:4011388
Sandberg M et al. Metabolically derived aspartate--elevated extracellular levels in vivo in lodoacetate poisoning. 1985 J. Neurosci. Res. pmid:4009740
Yoshizaki K et al. Intracellular pH measurement in frog muscle by means of 31P-nuclear magnetic resonance. 1979 Jpn. J. Physiol. pmid:40052
Scott-Ennis RJ and Noltmann EA Differential response of cysteine residues in pig muscle phosphoglucose isomerase to seven sulfhydryl-modifying reagents. 1985 Arch. Biochem. Biophys. pmid:4004250
Gottschalk WK and Sonneborn DR Evidence that Blastocladiella emersonii zoospore maintenance factor is a sulfhydryl group-containing cyclic ribotide. 1985 J. Biol. Chem. pmid:3997839
Holmes SD and Fairweather I Fasciola hepatica: motility response to metabolic inhibitors in vitro. 1985 Exp. Parasitol. pmid:3996521
Fernandez-Luna JL et al. Complete amino acid sequence of the Aspergillus cytotoxin mitogillin. 1985 Biochemistry pmid:3994994
Heilmaier HE and Summer KH Metallothionein content and zinc status in various tissues of rats treated with iodoacetic acid and zinc. 1985 Arch. Toxicol. pmid:3994507
Plishker GA Iodoacetic acid inhibition of calcium-dependent potassium efflux in red blood cells. 1985 Am. J. Physiol. pmid:3993768
Tanaka K et al. Effect of iodoacetate on local cerebral blood flow and glucose metabolism in cats: a double-radionuclide autoradiographic study. 1985 J. Cereb. Blood Flow Metab. pmid:3988828
Bagnasco S et al. Lactate production in isolated segments of the rat nephron. 1985 Am. J. Physiol. pmid:3985159
Spector R and Goetzl EJ Leukotriene C4 transport by the choroid plexus in vitro. 1985 Science pmid:3983632
Williams JM and Brandt KD Benoxaprofen reduces osteophyte formation and fibrillation after articular cartilage injury. 1985 J. Rheumatol. pmid:3981515
Ursini F et al. The selenoenzyme phospholipid hydroperoxide glutathione peroxidase. 1985 Biochim. Biophys. Acta pmid:3978121
Weiss J and Hiltbrand B Functional compartmentation of glycolytic versus oxidative metabolism in isolated rabbit heart. 1985 J. Clin. Invest. pmid:3973013
Connett RJ In vivo glycolytic equilibria in dog gracilis muscle. 1985 J. Biol. Chem. pmid:3972826
Kostner GM et al. Altered metabolism of low density lipoprotein in humans after prolonged incubation in plasma. 1985 Clin. Sci. pmid:3971671
Harris DC et al. Reduction potential of iron in transferrin. 1985 Biochim. Biophys. Acta pmid:3970972
Saito T and Yamaguchi J 2-Chloroadenosine: a selective lethal effect to mouse macrophages and its mechanism. 1985 J. Immunol. pmid:3968433