Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nerve Degeneration D009410 53 associated lipids
Pain D010146 64 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Brain Ischemia D002545 89 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Bell SD et al. RNA molecules that bind to and inhibit the active site of a tyrosine phosphatase. 1998 J. Biol. Chem. pmid:9603938
Holdobina OV [Changes in the total calcium content and in the activity of alkaline phosphatase and gamma-glutamyltransferase in the blood serum of rats with Mönckeberg's experimental arteriosclerosis]. 1998 Fiziol Zh pmid:9619411
Gilmour KM et al. Transepithelial potential of cultured branchial epithelia from rainbow trout under symmetrical conditions. 1998 In Vitro Cell. Dev. Biol. Anim. pmid:9661043
Post JA et al. pHe, [Ca2+]e, and cell death during metabolic inhibition: role of phospholipase A2 and sarcolemmal phospholipids. 1998 Am. J. Physiol. pmid:9458847
Prakash O and Bhushan G A study of inhibition of urease from seeds of the water melon (Citrullus vulgaris). 1998 J. Enzym. Inhib. pmid:9879515
Vega MC et al. The three-dimensional structure of Cys-47-modified mouse liver glutathione S-transferase P1-1. Carboxymethylation dramatically decreases the affinity for glutathione and is associated with a loss of electron density in the alphaB-310B region. 1998 J. Biol. Chem. pmid:9446594
Izumi Y et al. beta-Hydroxybutyrate fuels synaptic function during development. Histological and physiological evidence in rat hippocampal slices. 1998 J. Clin. Invest. pmid:9486983
Bullock AJ and Wray S The effects of metabolic inhibition on force, Ca2+ and pHi in guinea-pig ureteric smooth muscle. 1998 Pflugers Arch. pmid:9382937
Hacker TA et al. The role of glucose metabolism in a pig heart model of short-term hibernation. 1998 Mol. Cell. Biochem. pmid:9546633
Bakken IJ et al. [U-13C]glutamate metabolism in astrocytes during hypoglycemia and hypoxia. 1998 J. Neurosci. Res. pmid:9512008
Dizon J et al. Metabolic inhibition in the perfused rat heart: evidence for glycolytic requirement for normal sodium homeostasis. 1998 Am. J. Physiol. pmid:9575910
Schwarzbaum PJ et al. Functional role of ecto-ATPase activity in goldfish hepatocytes. 1998 Am. J. Physiol. pmid:9575966
Quick M and Jung H A conserved aspartate residue, Asp187, is important for Na+-dependent proline binding and transport by the Na+/proline transporter of Escherichia coli. 1998 Biochemistry pmid:9753469
Mastrogiacomo A et al. Intrinsic membrane association of Drosophila cysteine string proteins. 1998 FEBS Lett. pmid:9771899
Schumacher CA et al. Energy-dependent transport of calcium to the extracellular space during acute ischemia of the rat heart. 1998 J. Mol. Cell. Cardiol. pmid:9737948
Parry S et al. Identification of active-site histidine residues of a self-incompatibility ribonuclease from a wild tomato. 1997 Plant Physiol. pmid:9414554
Vezzoli A et al. Quantitative analysis of anaerobic metabolism in resting anoxic muscle by 31P and 1H MRS. 1997 Biochim. Biophys. Acta pmid:9452766
Agalakova NI et al. Differential effects of glycolytic and oxidative metabolism blockers on the Na-K pump in erythrocytes of the frog, Rana temporaria. 1997 J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. pmid:9404018
Nakayama S et al. Consequences of metabolic inhibition in smooth muscle isolated from guinea-pig stomach. 1997 J. Physiol. (Lond.) pmid:9409485
Kim H et al. Evidence for the essential histidine residues in geranylgeranyl transferase type I from bovine testis. 1997 Biochem. Mol. Biol. Int. pmid:9350353
Ness LS et al. Survival of Escherichia coli cells exposed to iodoacetate and chlorodinitrobenzene is independent of the glutathione-gated K+ efflux systems KefB and KefC. 1997 Appl. Environ. Microbiol. pmid:9327573
Sugimoto S et al. [A procedure for electroretinogram (ERG) recording in mice--effect of monoiodoacetic acid on the ERG in pigmented mice]. 1997 J Toxicol Sci pmid:9430091
Wu ML et al. Capacitative Ca2+ influx in glial cells is inhibited by glycolytic inhibitors. 1997 Glia pmid:9383040
Huang YC et al. Identification of the subunits and target peptides of pig heart NAD-specific isocitrate dehydrogenase modified by the affinity label 8-(4-bromo-2,3-dioxobutylthio)NAD. 1997 Arch. Biochem. Biophys. pmid:9390193
Izumi Y et al. Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation. 1997 J. Neurosci. pmid:9391000
Xu W et al. Identification of critical positive charges in XIP, the Na/Ca exchange inhibitory peptide. 1997 Arch. Biochem. Biophys. pmid:9169015
Rangarajan M et al. Biochemical characterization of the arginine-specific proteases of Porphyromonas gingivalis W50 suggests a common precursor. 1997 Biochem. J. pmid:9169603
Fang HK et al. Cardiac contractile function during coronary stenosis in dogs: association of adenosine in glycolytic dependence. 1997 Am. J. Physiol. pmid:9176286
Bender AS et al. The rapid L- and D-aspartate uptake in cultured astrocytes. 1997 Neurochem. Res. pmid:9178956
Burton FL and Smith GL The effect of cromakalim on intracellular [Ca2+] in isolated rat skeletal muscle during fatigue and metabolic blockade. 1997 Exp. Physiol. pmid:9179567
Kuwata K et al. Cross-relaxation times of normal and biochemically induced osteoarthritic rabbit knee cartilages. 1997 Jpn. J. Physiol. pmid:9271160
Rego AC et al. Adenosine triphosphate degradation products after oxidative stress and metabolic dysfunction in cultured retinal cells. 1997 J. Neurochem. pmid:9282947
Himmelreich U and Kuchel PW 13C-NMR studies of transmembrane electron transfer to extracellular ferricyanide in human erythrocytes. 1997 Eur. J. Biochem. pmid:9219520
Izumi Y et al. Monocarboxylates (pyruvate and lactate) as alternative energy substrates for the induction of long-term potentiation in rat hippocampal slices. 1997 Neurosci. Lett. pmid:9292881
Monika EM et al. A thioreduction pathway tethered to the membrane for periplasmic cytochromes c biogenesis; in vitro and in vivo studies. 1997 J. Mol. Biol. pmid:9299319
Santori G et al. Different efficacy of iodoacetic acid and N-ethylmaleimide in high-performance liquid chromatographic measurement of liver glutathione. 1997 J. Chromatogr. B Biomed. Sci. Appl. pmid:9300880
Gramolini A and Renaud JM Blocking ATP-sensitive K+ channel during metabolic inhibition impairs muscle contractility. 1997 Am. J. Physiol. pmid:9227423
Matthews RT et al. Iodoacetate produces striatal excitotoxic lesions. 1997 J. Neurochem. pmid:9202321
Xie LH et al. Development of inwardly rectifying K+ channel family in rat ventricular myocytes. 1997 Am. J. Physiol. pmid:9139958
Cappelli-Bigazzi M et al. Role of oxidative metabolism on endothelium-dependent vascular relaxation of isolated vessels. 1997 J. Mol. Cell. Cardiol. pmid:9152848
Carne AF and U S Chemical modification of proteins for sequence analysis. 1997 Methods Mol. Biol. pmid:9116830
Kajikawa H et al. Glucose transport by mixed ruminal bacteria from a cow. 1997 Appl. Environ. Microbiol. pmid:9143117
Peretz M et al. Cysteine reactivity in Thermoanaerobacter brockii alcohol dehydrogenase. 1997 Protein Sci. pmid:9144779
Nasu T and Baba K Mechanics of manganese ions-induced contraction of ileal longitudinal muscle in Ca(2+)-free, high-K+ medium. 1997 Gen. Pharmacol. pmid:9147016
Lorenz JN and Paul RJ Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. 1997 Am. J. Physiol. pmid:9124463
Jornot L et al. Modulation of the DNA binding activity of transcription factors CREP, NFkappaB and HSF by H2O2 and TNF alpha. Differences between in vivo and in vitro effects. 1997 FEBS Lett. pmid:9373190
Chen CJ et al. Characterization and purification of a lipoxygenase inhibitor in human epidermoid carcinoma A431 cells. 1997 Biochem. J. pmid:9355752
Waki A et al. Effects of antitumor agents on 3H-2-deoxyglucose uptake in tumor cells and their relationship with the main targets of the antitumor agents. 1997 Ann Nucl Med pmid:9310165
Clarke KA et al. Gait analysis in a rat model of osteoarthrosis. 1997 Physiol. Behav. pmid:9333186
Chandra A et al. Modification of aldose reductase by S-nitrosoglutathione. 1997 Biochemistry pmid:9398310