Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nerve Degeneration D009410 53 associated lipids
Pain D010146 64 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Brain Ischemia D002545 89 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Shi H and Adams C Rapid IC-ICP/MS method for simultaneous analysis of iodoacetic acids, bromoacetic acids, bromate, and other related halogenated compounds in water. 2009 Talanta pmid:19559915
Rogers DW et al. Transglutaminase-mediated semen coagulation controls sperm storage in the malaria mosquito. 2009 PLoS Biol. pmid:20027206
Wilson CG et al. Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications. 2009 Arthritis Res. Ther. pmid:19919704
Jinka R et al. Purification and characterization of cysteine protease from germinating cotyledons of horse gram. 2009 BMC Biochem. pmid:19919695
Harvey VL et al. A Selective Role for alpha3 Subunit Glycine Receptors in Inflammatory Pain. 2009 Front Mol Neurosci pmid:19915732
Lee SJ et al. Alterations in membrane transport function and cell viability induced by ATP depletion in primary cultured rabbit renal proximal tubular cells. 2009 Korean J. Physiol. Pharmacol. pmid:19885021
Galli GL et al. Ca2+ cycling in cardiomyocytes from a high-performance reptile, the varanid lizard (Varanus exanthematicus). 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19812356
Bar-Yehuda S et al. Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment. 2009 Arthritis Rheum. pmid:19790055
Tolonen AC et al. Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367. 2009 Mol. Microbiol. pmid:19775243
Castillo-Romero A et al. Participation of actin on Giardia lamblia growth and encystation. 2009 PLoS ONE pmid:19774081
Lur G et al. Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors. 2009 Curr. Biol. pmid:19765991
Charles RC et al. Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium. 2009 PLoS ONE pmid:19746165
Jones DP and Liang Y Measuring the poise of thiol/disulfide couples in vivo. 2009 Free Radic. Biol. Med. pmid:19715755
Volate S et al. TJ-41 Induces Apoptosis and Potentiates the Apoptotic Effects of 5-FU in Breast Cancer Cell Lines. 2009 J Oncol pmid:19710936
Powlesland AS et al. Targeted glycoproteomic identification of cancer cell glycosylation. 2009 Glycobiology pmid:19433864
Harvey VL and Dickenson AH Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice. 2009 Mol Pain pmid:19379487
Nochez Y et al. Acute and late-onset optic atrophy due to a novel OPA1 mutation leading to a mitochondrial coupling defect. 2009 Mol. Vis. pmid:19325939
Gandhi S et al. PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. 2009 Mol. Cell pmid:19285945
Sandercock DA et al. Changes in muscle cell cation regulation and meat quality traits are associated with genetic selection for high body weight and meat yield in broiler chickens. 2009 Genet. Sel. Evol. pmid:19284683
Wei WC et al. Requirement of focal adhesion kinase in branching tubulogenesis. 2009 J. Biomed. Sci. pmid:19272169
Lassiter C et al. HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction. 2009 AIDS Res Ther pmid:19193217
Miao J et al. 3-Carboxy-methyl-1,3-benzimidazolium-1-acetate monohydrate. 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21583676
Zhao R et al. Aqua-bis(2-iodo-acetato-κO)(1,10-phenanthroline-κN,N')copper(II). 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21581830
Clements KM et al. Cellular and histopathological changes in the infrapatellar fat pad in the monoiodoacetate model of osteoarthritis pain. 2009 Osteoarthr. Cartil. pmid:19114312
Santos-Rosa H et al. Histone H3 tail clipping regulates gene expression. 2009 Nat. Struct. Mol. Biol. pmid:19079264
Devalaraja-Narashimha K and Padanilam BJ PARP-1 inhibits glycolysis in ischemic kidneys. 2009 J. Am. Soc. Nephrol. pmid:19056868
Uyama T et al. The tumor suppressor gene H-Rev107 functions as a novel Ca2+-independent cytosolic phospholipase A1/2 of the thiol hydrolase type. 2009 J. Lipid Res. pmid:19047760
Ren J et al. Identification and quantification of 2',3'-cAMP release by the kidney. 2009 J. Pharmacol. Exp. Ther. pmid:19033554
Miao J et al. 1,3-Bis(carboxy-meth-yl)imidazolium triiodide 1-carboxyl-atomethyl-3-carboxy-methyl-imidazolium. 2009 Acta Crystallogr Sect E Struct Rep Online pmid:21583487
Cialdai C et al. Effect of Intra-articular 4-(S)-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl} piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a kinin B2 receptor antagonist, on nociceptive response in monosodium iodoacetate-induced experimental osteoarthritis in rats. 2009 J. Pharmacol. Exp. Ther. pmid:19745108
González-Reyes S et al. Neuroprotective role of heme-oxygenase 1 against iodoacetate-induced toxicity in rat cerebellar granule neurons: Role of bilirubin. 2009 Free Radic. Res. pmid:19177228
Xiang T et al. Localization and quantitation of free sulfhydryl in recombinant monoclonal antibodies by differential labeling with 12C and 13C iodoacetic acid and LC-MS analysis. 2009 Anal. Chem. pmid:19722496
Chumsae C et al. Identification and localization of unpaired cysteine residues in monoclonal antibodies by fluorescence labeling and mass spectrometry. 2009 Anal. Chem. pmid:19572546
Baragi VM et al. A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models. 2009 Arthritis Rheum. pmid:19565489
Suna H et al. Dysideamine, a new sesquiterpene aminoquinone, protects hippocampal neuronal cells against iodoacetic acid-induced cell death. 2009 Bioorg. Med. Chem. pmid:19414266
Shani V et al. Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia. 2009 J. Mol. Neurosci. pmid:18584337
Pilarski JQ et al. Effects of aerobic and anaerobic metabolic inhibitors on avian intrapulmonary chemoreceptors. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19297545
Machalińska A et al. Sodium iodate selectively injuries the posterior pole of the retina in a dose-dependent manner: morphological and electrophysiological study. 2010 Neurochem. Res. pmid:20725778
Ferreira-Gomes J et al. Phenotypic alterations of neurons that innervate osteoarthritic joints in rats. 2010 Arthritis Rheum. pmid:20722015
Fang M et al. Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat. 2010 Mol. Cancer pmid:20704698
Li M et al. A novel function for vimentin: the potential biomarker for predicting melanoma hematogenous metastasis. 2010 J. Exp. Clin. Cancer Res. pmid:20701774
Xu YD et al. The early asthmatic response is associated with glycolysis, calcium binding and mitochondria activity as revealed by proteomic analysis in rats. 2010 Respir. Res. pmid:20691077
Garner OB et al. Endothelial galectin-1 binds to specific glycans on nipah virus fusion protein and inhibits maturation, mobility, and function to block syncytia formation. 2010 PLoS Pathog. pmid:20657665
Swearingen CA et al. A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs. 2010 Osteoarthr. Cartil. pmid:20633676
Strassle BW et al. Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease. 2010 Osteoarthr. Cartil. pmid:20633675
Ochrietor JD et al. The 2M6 antigen is a Müller cell-specific intracellular membrane-associated protein of the sarcolemmal-membrane-associated protein family and is also TopAP. 2010 Mol. Vis. pmid:20577597
Im HJ et al. Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model. 2010 Arthritis Rheum. pmid:20556813
Castillo-Romero A et al. Rab11 and actin cytoskeleton participate in Giardia lamblia encystation, guiding the specific vesicles to the cyst wall. 2010 PLoS Negl Trop Dis pmid:20532229
Ivannikov MV et al. Calcium clearance and its energy requirements in cerebellar neurons. 2010 Cell Calcium pmid:20510449
Dalal P and Romani A Adenosine triphosphate depletion by cyanide results in a Na(+)-dependent Mg(2+) extrusion from liver cells. 2010 Metab. Clin. Exp. pmid:20494376
Gigliobianco T et al. Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. 2010 BMC Microbiol. pmid:20492686
Tsai JH et al. The protection of hepatocyte cells from the effects of oxidative stress by treatment with vitamin E in conjunction with DTT. 2010 J. Biomed. Biotechnol. pmid:20490359
Zhu Y et al. Differential gene expression in mouse retina related to regional differences in vulnerability to hyperoxia. 2010 Mol. Vis. pmid:20454693
Rodríguez E et al. Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. 2010 Int. J. Biol. Sci. pmid:20440403
Larriba MJ et al. Novel snail1 target proteins in human colon cancer identified by proteomic analysis. 2010 PLoS ONE pmid:20421926
Cifuentes DJ et al. Decrease in oxidative stress and histological changes induced by physical exercise calibrated in rats with osteoarthritis induced by monosodium iodoacetate. 2010 Osteoarthr. Cartil. pmid:20417294
Bloom HL et al. Statins Decrease Oxidative Stress and ICD Therapies. 2010 Cardiol Res Pract pmid:20369058
McGaraughty S et al. TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. 2010 Mol Pain pmid:20205719
Mann K et al. Phosphoproteomes of Strongylocentrotus purpuratus shell and tooth matrix: identification of a major acidic sea urchin tooth phosphoprotein, phosphodontin. 2010 Proteome Sci pmid:20181113
Calmettes G et al. Improved energy supply regulation in chronic hypoxic mouse counteracts hypoxia-induced altered cardiac energetics. 2010 PLoS ONE pmid:20174637
Edes K et al. JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1. 2010 PLoS ONE pmid:20098717
Kuduk SD et al. Synthesis, structure-activity relationship, and pharmacological profile of analogs of the ASIC-3 inhibitor A-317567. 2010 ACS Chem Neurosci pmid:22778804
Noyes PD et al. Characterizing the in vitro hepatic biotransformation of the flame retardant BDE 99 by common carp. 2010 Aquat. Toxicol. pmid:20080306
Kuzinski J et al. The vacuolar-type H-ATPase in ovine rumen epithelium is regulated by metabolic signals. 2010 J. Biomed. Biotechnol. pmid:20069127
Collas A et al. 2-(4-Formyl-2,6-dimeth-oxy-phenoxy)-acetic acid. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21589164
Evans C [3-(Iodo-acetamido)prop-yl]triphenyl-phospho-nium tetra-phenyl-borate. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21579806
Xu S et al. Transport of L-carnitine in human corneal and conjunctival epithelial cells. 2010 Mol. Vis. pmid:21045919
Qiao YL [Perspective of cervical cancer prevention and control in developing countries and areas]. 2010 Chin J Cancer pmid:20038301
González-Teuber M et al. Glucanases and chitinases as causal agents in the protection of Acacia extrafloral nectar from infestation by phytopathogens. 2010 Plant Physiol. pmid:20023149
Okamoto M and Atsuta Y Cartilage degeneration is associated with augmented chemically-induced joint pain in rats: a pilot study. 2010 Clin. Orthop. Relat. Res. pmid:20013164
Coombs PJ et al. Identification of novel contributions to high-affinity glycoprotein-receptor interactions using engineered ligands. 2010 J. Mol. Biol. pmid:20004209
Sniekers YH et al. Estrogen modulates iodoacetate-induced gene expression in bovine cartilage explants. 2010 J. Orthop. Res. pmid:19953602
North SJ et al. Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity. 2010 J. Biol. Chem. pmid:19951948
Samra ZQ et al. Synthesis of cholesterol-conjugated magnetic nanoparticles for purification of human paraoxonase 1. 2010 Appl. Biochem. Biotechnol. pmid:19902382
Liviac D et al. Genotoxicity testing of three monohaloacetic acids in TK6 cells using the cytokinesis-block micronucleus assay. 2010 Mutagenesis pmid:20547559
Miao J et al. 2-Oxo-2,3-dihydro-1H-imidazo[1,2-a]pyridinium iodide. 2010 Acta Crystallogr Sect E Struct Rep Online pmid:21580362
Sagar DR et al. Tonic modulation of spinal hyperexcitability by the endocannabinoid receptor system in a rat model of osteoarthritis pain. 2010 Arthritis Rheum. pmid:20722027
Chambers JE et al. The reduction potential of the active site disulfides of human protein disulfide isomerase limits oxidation of the enzyme by Ero1α. 2010 J. Biol. Chem. pmid:20657012
Yoshimi E et al. Sustained analgesic effect of the Rho kinase inhibitor AS1892802 in rat models of chronic pain. 2010 J. Pharmacol. Sci. pmid:20710117
Rao Y et al. Mapping of selenium metabolic pathway in yeast by liquid chromatography-Orbitrap mass spectrometry. 2010 Anal. Chem. pmid:20825195
Wada M and Shirahata A Conformational stabilization of rat s-adenosylmethionine decarboxylase by putrescine. 2010 Biol. Pharm. Bull. pmid:21048303
Hall AM et al. Albumin uptake in OK cells exposed to rotenone: a model for studying the effects of mitochondrial dysfunction on endocytosis in the proximal tubule? 2010 Nephron Physiol pmid:20484937
Wartenberg M et al. Glycolytic pyruvate regulates P-Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state. 2010 J. Cell. Biochem. pmid:19950199
Nagarathnam R et al. Purification and properties of cysteine protease from rhizomes of Curcuma longa (Linn.). 2010 J. Sci. Food Agric. pmid:20355018
Yang D et al. Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L). 2010 Cancer Biol. Ther. pmid:19923925
Liu H et al. Domain-level stability of an antibody monitored by reduction, differential alkylation, and mass spectrometry analysis. 2010 Anal. Biochem. pmid:20152794
Chu CR et al. In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage. 2010 J Bone Joint Surg Am pmid:20194318
Rodríguez SB et al. Cysteine 351 is an essential nucleophile in catalysis by Porphyromonas gingivalis peptidylarginine deiminase. 2010 Arch. Biochem. Biophys. pmid:20850413
Saudemont A et al. Ancestral regulatory circuits governing ectoderm patterning downstream of Nodal and BMP2/4 revealed by gene regulatory network analysis in an echinoderm. 2010 PLoS Genet. pmid:21203442
Catterall JB et al. Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254). 2010 Arthritis Res. Ther. pmid:21194441
Sarigianni M et al. Involvement of signaling molecules on na/h exchanger-1 activity in human monocytes. 2010 Open Cardiovasc Med J pmid:21160910
Gupta K et al. Identification, activity and disulfide connectivity of C-di-GMP regulating proteins in Mycobacterium tuberculosis. 2010 PLoS ONE pmid:21151497
Tavender TJ et al. Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum. 2010 EMBO J. pmid:21057456
Iyer SS et al. Effect of bone marrow-derived mesenchymal stem cells on endotoxin-induced oxidation of plasma cysteine and glutathione in mice. 2010 Stem Cells Int pmid:21048855
Madry C et al. The role of pannexin hemichannels in the anoxic depolarization of hippocampal pyramidal cells. 2010 Brain pmid:20940167
Bittner CX et al. High resolution measurement of the glycolytic rate. 2010 Front Neuroenergetics pmid:20890447
Schuelert N et al. Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain. 2010 Osteoarthr. Cartil. pmid:20863899
Eby WM et al. Hyperbolastic modeling of tumor growth with a combined treatment of iodoacetate and dimethylsulphoxide. 2010 BMC Cancer pmid:20863400
Li SC et al. Chicken model of steroid-induced bone marrow adipogenesis using proteome analysis: a preliminary study. 2010 Proteome Sci pmid:20840762
Lin D et al. Cysteinyl peptide capture for shotgun proteomics: global assessment of chemoselective fractionation. 2010 J. Proteome Res. pmid:20731415