Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nerve Degeneration D009410 53 associated lipids
Pain D010146 64 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Brain Ischemia D002545 89 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Balhorn R et al. Identification of bull protamine disulfides. 1991 Biochemistry pmid:1988019
Yamada R and Bradshaw RA Rat liver polysome N alpha-acetyltransferase: isolation and characterization. 1991 Biochemistry pmid:1989673
Cummings JG et al. Reductive half-reaction in medium-chain acyl-CoA dehydrogenase: modulation of internal equilibrium by carboxymethylation of a specific methionine residue. 1992 Biochemistry pmid:1390638
Lawson SL et al. Effects of both shortening and lengthening the active site nucleophile of Bacillus circulans xylanase on catalytic activity. 1996 Biochemistry pmid:8756474
Collinson IR et al. The F1F0-ATPase complex from bovine heart mitochondria: the molar ratio of the subunits in the stalk region linking the F1 and F0 domains. 1996 Biochemistry pmid:8823202
Xiong H et al. Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase. 1999 Biochemistry pmid:10029540
Fujioka M et al. Function and reactivity of sulfhydryl groups of rat liver glycine methyltransferase. 1987 Biochemistry pmid:3676278
Hatcher VB et al. Purification, properties, and partial structure elucidation of a high-molecular-weight glycoprotein from cervical mucus of the bonnet monkey (Macaca radiata). 1977 Biochemistry pmid:402940
Mizzer JP and Thorpe C An essential methionine in pig kidney general acyl-CoA dehydrogenase. 1980 Biochemistry pmid:7459327
Flitsch SL and Khorana HG Structural studies on transmembrane proteins. 1. Model study using bacteriorhodopsin mutants containing single cysteine residues. 1989 Biochemistry pmid:2692704
Raia CA et al. Activation of Sulfolobus solfataricus alcohol dehydrogenase by modification of cysteine residue 38 with iodoacetic acid. 1996 Biochemistry pmid:8555238
Turner E et al. Ovothiols, a family of redox-active mercaptohistidine compounds from marine invertebrate eggs. 1987 Biochemistry pmid:3651433
Hermsdorf CL Tripeptide-specific aminopeptidase from Escherichia coli AJ005. 1978 Biochemistry pmid:356879
Lee JJ and Fasco MJ Metabolism of vitamin K and vitamin K 2,3-epoxide via interaction with a common disulfide. 1984 Biochemistry pmid:6733086
Dunbar JC and Bradshaw RA Amino acid sequence of guinea pig prostate kallikrein. 1987 Biochemistry pmid:3307909
Campbell-Burk SL et al. 31P NMR saturation-transfer measurements in Saccharomyces cerevisiae: characterization of phosphate exchange reactions by iodoacetate and antimycin A inhibition. 1987 Biochemistry pmid:3322400
Sahin-Tóth M and Kaback HR Functional conservation in the putative substrate binding site of the sucrose permease from Escherichia coli. 2000 Biochemistry pmid:10821691
Charbonneau H et al. Amino acid sequence of the calcium-dependent photoprotein aequorin. 1985 Biochemistry pmid:2866797
Fujioka M et al. Recombinant rat liver guanidinoacetate methyltransferase: reactivity and function of sulfhydryl groups. 1988 Biochemistry pmid:3207695
Lee FS et al. Primary structure of human placental ribonuclease inhibitor. 1988 Biochemistry pmid:3219362
Waheed A et al. Purification and physicochemical characterization of a human placental acid phosphatase possessing phosphotyrosyl protein phosphatase activity. 1988 Biochemistry pmid:2844226
Kaslow HR and Lesikar DD Sulfhydryl-alkylating reagents inactivate the NAD glycohydrolase activity of pertussis toxin. 1987 Biochemistry pmid:2822091
Nakamura CE and Abeles RH Mode of interaction of beta-hydroxy-beta-methylglutaryl coenzyme A reductase with strong binding inhibitors: compactin and related compounds. 1985 Biochemistry pmid:3886005
Evans AC and Wilkinson KD Ubiquitin-dependent proteolysis of native and alkylated bovine serum albumin: effects of protein structure and ATP concentration on selectivity. 1985 Biochemistry pmid:2990536
Zimmerle CT and Alter GM Crystallization-induced modification of cytoplasmic malate dehydrogenase structure and function. 1983 Biochemistry pmid:6661435
Forstrom JW et al. Identification of the catalytic site of rat liver glutathione peroxidase as selenocysteine. 1978 Biochemistry pmid:678534
Thomas ML and Tack BF Identification and alignment of a thiol ester site in the third component of guinea pig complement. 1983 Biochemistry pmid:6838833
Bosron WF et al. Selective carboxymethylation of cysteine-174 of the beta 2 beta 2 and beta 1 beta 1 human liver alcohol dehydrogenase isoenzymes by iodoacetate. 1986 Biochemistry pmid:2939875
Donadio S et al. Alkylation of amide linkages and cleavage of the C chain in the enzyme-activated-substrate inhibition of alpha-chymotrypsin with N-nitrosamides. 1985 Biochemistry pmid:4016069
Ralat LA and Colman RF Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. 2006 Biochemistry pmid:17029404
Rudnick G and Abeles RH Reaction mechanism and structure of the active site of proline racemase. 1975 Biochemistry pmid:1174513
Chicheportiche R et al. Structure-function relationship in the binding of snake neurotoxins to the torpedo membrane receptor. 1975 Biochemistry pmid:1148159
Zhang ZY et al. Covalent modification and active site-directed inactivation of a low molecular weight phosphotyrosyl protein phosphatase. 1992 Biochemistry pmid:1737025
Herzfeld J et al. Molecular symmetry and metastable states of enzymes exhibiting half-of-the-sites reactivity. 1981 Biochemistry pmid:7028097
Beyer WF and Fridovich I Pseudocatalase from Lactobacillus plantarum: evidence for a homopentameric structure containing two atoms of manganese per subunit. 1985 Biochemistry pmid:4084532
Ashiba G and Szent-Györgyi AG Essential light chain exchange in scallop myosin. 1985 Biochemistry pmid:4084545
Brindle KM 31P NMR magnetization-transfer measurements of flux between inorganic phosphate and adenosine 5'-triphosphate in yeast cells genetically modified to overproduce phosphoglycerate kinase. 1988 Biochemistry pmid:3056522
Fraij B and Hartman FC Isolation and sequencing of an active-site peptide from Rhodospirillum rubrum ribulosebisphosphate carboxylase/oxygenase after affinity labeling with 2-[(bromoacetyl)amino]pentitol 1,5-bisphosphate. 1983 Biochemistry pmid:6404301
Dayton WR et al. A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Partial characterization of the purified enzyme. 1976 Biochemistry pmid:1276131
Habersetzer-Rochat C and Sampieri F Structure-function relationships of scorpion neurotoxins. 1976 Biochemistry pmid:819030
Nagae S et al. Purification and properties of a neutral endodeoxyribonuclease from rat small intestinal mucosa. 1982 Biochemistry pmid:7074091
Denu JM et al. The catalytic role of aspartic acid-92 in a human dual-specific protein-tyrosine-phosphatase. 1995 Biochemistry pmid:7880835
Zhang ZY et al. Catalytic function of the conserved hydroxyl group in the protein tyrosine phosphatase signature motif. 1995 Biochemistry pmid:8845365
Byers LD and Koshland DE The specificity of induced conformational changes. The case of yeast glyceraldehyde-3-phosphate dehydrogenase. 1975 Biochemistry pmid:169882
Mende TJ and Moreno M A heat stable paraoxonase (O,O-diethyl O-p-nitrophenyl phosphate O-p-nitrophenyl hydrolase) from Russell's viper venom. 1975 Biochemistry pmid:169891
Reynolds EE et al. Adenosine 5'-triphosphate independent secretion from PC12 pheochromocytoma cells. 1982 Biochemistry pmid:7138829
Sharma HK The fast-reacting sulfhydryl group of rat muscle phosphoglycerate kinase is necessary for activity and maintenance of tertiary structure. 1982 Biochemistry pmid:7159552
Franzen JS et al. Half-of-the-sites reactivity of bovine liver uridine diphosphoglucose dehydrogenase toward iodoacetate and iodoacetamide. 1976 Biochemistry pmid:187220
Coulin F et al. Identification of Cys-150 in the active site of phosphomannose isomerase from Candida albicans. 1993 Biochemistry pmid:8260497
Chandra A et al. Modification of aldose reductase by S-nitrosoglutathione. 1997 Biochemistry pmid:9398310
Dadlez M and Kim PS Rapid formation of the native 14-38 disulfide bond in the early stages of BPTI folding. 1996 Biochemistry pmid:8973187
Ehrlich RS and Colman RF Coenzyme binding by native and chemically modified pig heart triphosphopyridine nucleotide dependent isocitrate dehydrogenase. 1975 Biochemistry pmid:241396
Larsson LJ et al. Subunits of human alpha 2-macroglobulin produced by specific reduction of interchain disulfide bonds with thioredoxin. 1988 Biochemistry pmid:2452651
Kingsley-Hickman PB et al. 31P NMR studies of ATP synthesis and hydrolysis kinetics in the intact myocardium. 1987 Biochemistry pmid:3427090
Knipping G et al. Action of lecithin-cholesterol acyltransferase on low-density lipoproteins in native pig plasma. 1987 Biochemistry pmid:3427116
Dubois T et al. Comparison between the folding of reduced hen egg white lysozyme and that of reduced human milk lysozyme. 1982 Biochemistry pmid:7150571
Zhang ZY and Dixon JE Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402. 1993 Biochemistry pmid:8369304
Ohnoki S et al. Glutamine active site of formylglycinamide ribonucleotide amidotransferase. 1. Labeling of the enzyme with iodoacetate. 1977 Biochemistry pmid:14669
Wu L and Zhang ZY Probing the function of Asp128 in the lower molecular weight protein-tyrosine phosphatase-catalyzed reaction. A pre-steady-state and steady-state kinetic investigation. 1996 Biochemistry pmid:8611532
Quick M and Jung H A conserved aspartate residue, Asp187, is important for Na+-dependent proline binding and transport by the Na+/proline transporter of Escherichia coli. 1998 Biochemistry pmid:9753469
Ohta A et al. Effect of lipid peroxidation on membrane-bound Ca2+-ATPase activity of the intestinal brush-border membranes. 1989 Biochim. Biophys. Acta pmid:2527563
DiPolo R and Caputo C The effect of ATP on calcium efflux in dialyzed barnacle muscle fibres. 1977 Biochim. Biophys. Acta pmid:411508
Svasti J and Talupphet N Improvement in the resolution of human sperm protamines by use of iodoacetamide as alkylating agent. 1979 Biochim. Biophys. Acta pmid:427214
Boehm EA et al. The utilisation of creatine and its analogues by cytosolic and mitochondrial creatine kinase. 1996 Biochim. Biophys. Acta pmid:8664304
Ott P and Brodbeck U Amphiphile dependency of the monomeric and dimeric forms of acetylcholinesterase from human erythrocyte membrane. 1984 Biochim. Biophys. Acta pmid:6466662
Cooke KR Effect of the CO-2-bicarbonate buffer system on the water and ion contents of rat renal cortical slices. 1976 Biochim. Biophys. Acta pmid:949507
Thoma WJ and UÄŸurbil K Saturation-transfer studies of ATP-Pi exchange in isolated perfused rat liver. 1987 Biochim. Biophys. Acta pmid:2887203
Waheed A and Van Etten RL Sulfhydryl groups of rabbit liver arylsulfatase A. 1985 Biochim. Biophys. Acta pmid:2864083
Malik MN et al. Third form of calcium-activated neutral proteinase from calf brain: purification, partial characterization and comparison of properties with other forms. 1987 Biochim. Biophys. Acta pmid:2822124
Myöhänen T and Mäntsälä P Evidence for the importance of cysteine and arginine residues in Pseudomonas fluorescens UK-1 pantoate dehydrogenase. 1980 Biochim. Biophys. Acta pmid:6773579
Seppänen P et al. Polyamine deprivation-induced enhanced uptake of methylglyoxal bis(guanylhydrazone) by tumor cells. 1981 Biochim. Biophys. Acta pmid:6786360
Chen CH et al. Synthesis and secretion of lecithin-cholesterol acyltransferase by the human hepatoma cell line HepG2. 1986 Biochim. Biophys. Acta pmid:3015221
Liao TH et al. Deoxyribonuclease II purified from the isolated lysosomes of porcine spleen and from porcine liver homogenates. Comparison with deoxyribonuclease II purified from porcine spleen homogenates. 1989 Biochim. Biophys. Acta pmid:2909240
Barron JT et al. Effects of ATP reduction on the pattern of force development and myosin light chain phosphorylation in intact arterial smooth muscle. 1989 Biochim. Biophys. Acta pmid:2912507
Martínez-Izquierdo JA et al. Role of the adenylate system and glycolytic flux in the control of protein synthesis in isolated rat lung cells. 1982 Biochim. Biophys. Acta pmid:6291628
Ostenson CG et al. Effects of metabolic inhibitors on the regulation of pancreatic glucagon release. 1980 Biochim. Biophys. Acta pmid:6986917
Bode HP et al. Vanadium uptake by yeast cells. 1990 Biochim. Biophys. Acta pmid:2155019
Foxall DL et al. The inhibition of erythrocyte glyceraldehyde-3-phosphate dehydrogenase. In situ PMR studies. 1984 Biochim. Biophys. Acta pmid:6372868
Boxman AW et al. Some characteristics of tetraphenylphosphonium uptake into Saccharomyces cerevisiae. 1982 Biochim. Biophys. Acta pmid:7039677
Pliszka B and Lu RC Reactivities of thiols in myosin rod: effect of magnesium and ionic strength. 1985 Biochim. Biophys. Acta pmid:4027253
Yada T et al. Synchronous oscillation of the cytoplasmic Ca2+ concentration and membrane potential in cultured epithelial cells (Intestine 407). 1986 Biochim. Biophys. Acta pmid:3085731
Le Gaillard F et al. Reversible dissociation of cortisol-transcortin complex by sodium para-chloromercuribenzoate. 1983 Biochim. Biophys. Acta pmid:6419776
Morand O et al. Effect of albumin, low temperature and metabolic inhibitors on transport of fatty acids into cultured human leukemic myeloid cells. 1982 Biochim. Biophys. Acta pmid:6960927
Liu SQ et al. Carboxymethylation-induced activation of bovine lens aldose reductase. 1992 Biochim. Biophys. Acta pmid:1576159
Hojring N and Svensmark O Carboxylesterases of human brain extract. Purification and properties of a butyrylesterase. 1977 Biochim. Biophys. Acta pmid:857894
Siksnys V and Pleckaityte M Role of the reactive cysteine residue in restriction endonuclease Cfr9I. 1992 Biochim. Biophys. Acta pmid:1332782
Fuhrmann GF et al. The effect of ferricyanide with iodoacetate in calcium-free solution on passive cation permeability in human red blood cells: comparison with the Gardos-effect and with the influence of PCMBS on passive cation permeability. 1989 Biochim. Biophys. Acta pmid:2547446
Plagemann PG et al. Adenine nucleotide metabolism and nucleoside transport in human erythrocytes under ATP depletion conditions. 1985 Biochim. Biophys. Acta pmid:3873962
Marrone L and Viswanatha T Effect of selective cysteine --> alanine replacements on the catalytic functions of lysine: N6-hydroxylase. 1997 Biochim. Biophys. Acta pmid:9434117
Pierce S and Tappel AL Glutathione peroxidase activities from rat liver. 1978 Biochim. Biophys. Acta pmid:629991
Bhatnagar A et al. Human placental aldose reductase: role of Cys-298 in substrate and inhibitor binding. 1994 Biochim. Biophys. Acta pmid:8155699
Vessey DA and Benfatto AM Chemical modification of bile acid: CoA ligase. 1993 Biochim. Biophys. Acta pmid:8218381
Calonge ML et al. Intracellular pH regulation in cecal epithelial cells from the chick. 1993 Biochim. Biophys. Acta pmid:8274490
Heinonen E and Akerman KE Intracellular free magnesium in synaptosomes measured with entrapped eriochrome blue. 1987 Biochim. Biophys. Acta pmid:2436663
Ferri G et al. Chloroplast glyceraldehyde-3-phosphate dehydrogenase (NADP+). Reactivity of essential cysteine residues in holo- and apoenzyme. 1981 Biochim. Biophys. Acta pmid:7284406
Duncan R and Lloyd JB Pinocytosis in the rat visceral yolk sac. Effects of temperature, metabolic inhibitors and some other modifiers. 1978 Biochim. Biophys. Acta pmid:103581
Mandelbaum-Shavit F Resistance to Pediococcus cerevisiae to amethopterin as a consequence of changes in enzymatic activity and cell permeability. II. Permeability changes to amethopterin and other folates in the drug-resistant mutant. 1976 Biochim. Biophys. Acta pmid:6055
Suzuki Y et al. Purification and properties of extracellular alpha-glucosidase of a thermophile, Bacillus thermoglucosidus KP 1006. 1976 Biochim. Biophys. Acta pmid:8145
Kuo SC and Lampen JO Action of cytochalasin A, a sulfhydryl-reactive agent, on sugar metabolism and membrane-bound adenosine triphosphatase of yeast. 1975 Biochim. Biophys. Acta pmid:124588
Franzen JS et al. Induced versus pre-existing asymmetry models for the half-of-the-sites reactivity effect in bovine liver uridine diphosphoglucose dehydrogenase. 1980 Biochim. Biophys. Acta pmid:7407191