Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Starvation D013217 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Nerve Degeneration D009410 53 associated lipids
Pain D010146 64 associated lipids
Reperfusion Injury D015427 65 associated lipids
Mammary Neoplasms, Experimental D008325 67 associated lipids
Coronary Disease D003327 70 associated lipids
Hyperlipidemias D006949 73 associated lipids
Brain Ischemia D002545 89 associated lipids
Glioma D005910 112 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Ito Y et al. Oxidative stress increases glyceraldehyde-3-phosphate dehydrogenase mRNA levels in isolated rabbit aorta. 1996 Am. J. Physiol. pmid:8769737
Plishker GA et al. Involvement of a cytoplasmic protein in calcium-dependent potassium efflux in red blood cells. 1986 Am. J. Physiol. pmid:3532815
Wu Y et al. Alterations in reactive oxygen, pH, and calcium in astrocytoma cells during lethal injury. 1996 Am. J. Physiol. pmid:8772436
Matsumoto Y et al. Creatine kinase kinetics in diabetic cardiomyopathy. 1995 Am. J. Physiol. pmid:7611380
Satoh H and Vassalle M Role of calcium in caffeine-norepinephrine interactions in cardiac Purkinje fibers. 1989 Am. J. Physiol. pmid:2750939
Gores GJ et al. Swelling, reductive stress, and cell death during chemical hypoxia in hepatocytes. 1989 Am. J. Physiol. pmid:2764095
Conrad CH et al. Outward current and repolarization in hypoxic rat myocardium. 1983 Am. J. Physiol. pmid:6829776
Griendling KK et al. Pregnancy-induced changes in sheep uterine and carotid arteries. 1985 Am. J. Physiol. pmid:2581458
Alvarado RH et al. Chloride transport across isolated skin of Rana pipiens. 1975 Am. J. Physiol. pmid:1082245
Bagnasco S et al. Lactate production in isolated segments of the rat nephron. 1985 Am. J. Physiol. pmid:3985159
Plishker GA Iodoacetic acid inhibition of calcium-dependent potassium efflux in red blood cells. 1985 Am. J. Physiol. pmid:3993768
Beauwens R et al. Polycations reduce vasopressin-induced water flow by endocytic removal of water channels. 1986 Am. J. Physiol. pmid:3010730
Sick TJ et al. Brain potassium ion homeostasis, anoxia, and metabolic inhibition in turtles and rats. 1982 Am. J. Physiol. pmid:6287869
SANDOW A and KARCZMAR AG Effect of iodoacetate on changes in muscular latency induced by activity. 1950 Am. J. Physiol. pmid:14789991
Shryock JC et al. Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. 1988 Am. J. Physiol. pmid:3344813
DiGregorio KA et al. Measurement of superoxide release from single pulmonary alveolar macrophages. 1987 Am. J. Physiol. pmid:3035935
Plishker GA Effects of cadmium and zinc on calcium uptake in human red blood cells. 1984 Am. J. Physiol. pmid:6089571
Strewler GJ Release of cAMP from a renal epithelial cell line. 1984 Am. J. Physiol. pmid:6322592
Murphy E et al. Biochemical and structural changes in cultured heart cells induced by metabolic inhibition. 1987 Am. J. Physiol. pmid:3688218
Norris SH and Hersey SJ Stimulation of pepsinogen secretion in permeable isolated gastric glands. 1985 Am. J. Physiol. pmid:3876033
Sumpio BE and Maack T Kinetics, competition, and selectivity of tubular absorption of proteins. 1982 Am. J. Physiol. pmid:7124951
Hartmund T and Gesser H Cardiac force and high-energy phosphates under metabolic inhibition in four ectothermic vertebrates. 1996 Am. J. Physiol. pmid:8897986
Apstein CS et al. Acute cardiac ischemia and reperfusion: contractility, relaxation, and glycolysis. 1978 Am. J. Physiol. pmid:736151
Rodríguez-Estrada C Reduced nicotinamide adenine dinucleotide and depolarization in neurons. 1975 Am. J. Physiol. pmid:165729
Koss KL and Grubbs RD Elevated extracellular Mg2+ increases Mg2+ buffering through a Ca-dependent mechanism in cardiomyocytes. 1994 Am. J. Physiol. pmid:8074196
Xie LH et al. Development of inwardly rectifying K+ channel family in rat ventricular myocytes. 1997 Am. J. Physiol. pmid:9139958
Pautler EL et al. Modification of leucine transport across bovine pigment epithelium by metabolic stress. 1989 Am. J. Physiol. pmid:2596588
Lorenz JN and Paul RJ Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. 1997 Am. J. Physiol. pmid:9124463
Gores GJ et al. Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes. 1988 Am. J. Physiol. pmid:3421314
Nakamura K et al. Glycolysis is necessary to preserve myocardial Ca2+ homeostasis during beta-adrenergic stimulation. 1993 Am. J. Physiol. pmid:8384419
Ahearn GA Intestinal electrophysiology and transmural ion transport in freshwater prawns. 1980 Am. J. Physiol. pmid:7395980
Greenwood SL et al. Transtrophoblast and microvillus membrane potential difference in mature intermediate human placental villi. 1993 Am. J. Physiol. pmid:8368275
Miyazaki Y et al. Selective turnover of sarcolemmal phospholipids with lethal cardiac myocyte injury. 1990 Am. J. Physiol. pmid:2382705
Okamoto K et al. ATP from glycolysis is required for normal sodium homeostasis in resting fast-twitch rodent skeletal muscle. 2001 Am. J. Physiol. Endocrinol. Metab. pmid:11500303
Harrison GJ et al. Glycolytic buffering affects cardiac bioenergetic signaling and contractile reserve similar to creatine kinase. 2003 Am. J. Physiol. Heart Circ. Physiol. pmid:12714331
Zhou L et al. Impact of anaerobic glycolysis and oxidative substrate selection on contractile function and mechanical efficiency during moderate severity ischemia. 2008 Am. J. Physiol. Heart Circ. Physiol. pmid:18660443
Raddatz E et al. Differential contribution of mitochondria, NADPH oxidases, and glycolysis to region-specific oxidant stress in the anoxic-reoxygenated embryonic heart. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21193588
Chen F et al. Effects of metabolic inhibition on conduction, Ca transients, and arrhythmia vulnerability in embryonic mouse hearts. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17660398
Singla DK et al. TGF-β2 treatment enhances cytoprotective factors released from embryonic stem cells and inhibits apoptosis in infarcted myocardium. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21297031
Merker MP et al. Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells. 2002 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:11741813
Galli GL et al. Ca2+ cycling in cardiomyocytes from a high-performance reptile, the varanid lizard (Varanus exanthematicus). 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19812356
Pilarski JQ et al. Effects of aerobic and anaerobic metabolic inhibitors on avian intrapulmonary chemoreceptors. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19297545
Cheng AM et al. Energy dependence of restitution in the gastric mucosa. 2001 Am. J. Physiol., Cell Physiol. pmid:11443042
Yanagawa N et al. Riboflavin transport by isolated perfused rabbit renal proximal tubules. 2000 Am. J. Physiol., Cell Physiol. pmid:11078692
Aromolaran AS et al. Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. 2007 Am. J. Physiol., Cell Physiol. pmid:17344311
Gustafson SB et al. Evaluation of intra-articularly administered sodium monoiodoacetate-induced chemical injury to articular cartilage of horses. 1992 Am. J. Vet. Res. pmid:1497191
Yovich JV et al. Effects of polysulfated glycosaminoglycan on chemical and physical defects in equine articular cartilage. 1987 Am. J. Vet. Res. pmid:3662210
Roe SC et al. Biomechanical properties of canine cortical bone allografts: effects of preparation and storage. 1988 Am. J. Vet. Res. pmid:3041883
Nakai T et al. Characterization of the hemolysin produced by haemophilus pleuropneumoniae. 1983 Am. J. Vet. Res. pmid:6830024
Von Behren LA and Pesanti EL Uptake and degradation of Pneumocystis carinii by macrophages in vitro. 1978 Am. Rev. Respir. Dis. pmid:369410