| MeSH term | MeSH ID | Detail |
|---|---|---|
| Temporomandibular Joint Disorders | D013705 | 4 associated lipids |
| Arthralgia | D018771 | 8 associated lipids |
| Osteophyte | D054850 | 2 associated lipids |
| Glycogen Storage Disease | D006008 | 4 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Retinitis | D012173 | 4 associated lipids |
| Theileriasis | D013801 | 7 associated lipids |
| Muscle Cramp | D009120 | 3 associated lipids |
| Rigor Mortis | D012298 | 1 associated lipids |
| Thrombophilia | D019851 | 6 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Jezek P et al. | Important amino acid residues of potato plant uncoupling protein (StUCP). | 2000 | Braz. J. Med. Biol. Res. | pmid:11105092 |
| Unni E et al. | Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro. | 2005 | Breast Cancer Res. | pmid:16168115 |
| Roullet B et al. | [Determination of serum glycosylated proteins in normoglycemic patients with cancer]. | 1987 | Bull Cancer | pmid:3435788 |
| Gupta SR et al. | Effect of some inhibitors on aflatoxin-production in a synthetic medium and on the incorporation of acetate-1- 14C into aflatoxins by resting mycelia of Aspergillus parasiticus. | 1976 | Bull Environ Contam Toxicol | pmid:1260151 |
| CHASSIN JL and LOCALIO SA | The biological chemistry of wound healing; effect of blocking the sulfhydryl group (-SH) in vivo with iodoacetic acid. | 1949 | Bull N Y Acad Med | pmid:18152259 |
| Boiledieu D and Valembois P | [Evidence for polypeptide synthesis during cytotoxic reactions in sipunculid worms]. | 1978 | C. R. Seances Soc. Biol. Fil. | pmid:80257 |
| Ramp WK et al. | Magnesium and the mineral metabolism of chick embryo tibiae in organ culture. | 1977 | Calcif Tissue Res | pmid:563764 |
| Scarpace PJ and Neuman WF | The blood: bone disequilibrium. I. The active accumulation of K+ into the bone extracellular fluid. | 1976 | Calcif Tissue Res | pmid:1260484 |
| Scarpace PJ and Neuman WF | The blood: bone disequilibrium. II. Evidence against the active accumulation of calcium or phosphate into the bone extracellular fluid. | 1976 | Calcif Tissue Res | pmid:1260485 |
| Ramp WK et al. | Effects of ethanol on chicks in vivo and on chick embryo tibiae in organ culture. | 1975 | Calcif Tissue Res | pmid:1148882 |
| Hicks EP and Ramp WK | The effects of fluoride on the mineralization of embryonic chick tibiae in organ culture. | 1975 | Calcif Tissue Res | pmid:1148883 |
| Chikuma T et al. | Properties of Suc-GPLGP-MCAase and dipeptidyl-aminopeptidase in mouse calvaria-derived osteoblastic cells (MC3T3-E1). | 1985 | Calcif. Tissue Int. | pmid:2988719 |
| Nijweide PJ and van der Plas A | Regulation of calcium transport in isolated periosteal cells, effects of hormones and metabolic inhibitors. | 1979 | Calcif. Tissue Int. | pmid:116755 |
| McCall D et al. | Effect of ischemia-related metabolic factors on thallium exchange in cultured rat myocardial cells. | 1986 May-Jun | Can J Cardiol | pmid:2424579 |
| Huber RE and Mathison RD | Physical, chemical, and enzymatic studies on the major sucrase of honey bees (Apis mellifera). | 1976 | Can. J. Biochem. | pmid:4203 |
| Callahan JW and Gerrie J | GM1-ganglioside and lactosylceramide beta-galactosidase from rabbit brain: inhibitor and substrate competition studies. | 1976 | Can. J. Biochem. | pmid:971464 |
| Carne TJ et al. | Studies on phosphoglyceromutase from chicken breast muscle: number and reactivity of sulfhydryl groups. | 1976 | Can. J. Biochem. | pmid:178418 |
| Lazure C et al. | Primary structure determination of Escherichia coli heat-stable enterotoxin of porcine origin. | 1983 | Can. J. Biochem. Cell Biol. | pmid:6349752 |
| Schellhorn HE and Hassan HM | Response of hydroperoxidase and superoxide dismutase deficient mutants of Escherichia coli K-12 to oxidative stress. | 1988 | Can. J. Microbiol. | pmid:2848619 |
| Bryant RD et al. | The role of Thiobacillus albertis glycocalyx in the adhesion of cells to elemental sulfur. | 1984 | Can. J. Microbiol. | pmid:6713305 |
| Hoban DJ and Lyric RM | Glutamate uptake in Thiobacillus novellus. | 1977 | Can. J. Microbiol. | pmid:856422 |
| Aspedon A and Nickerson KW | The energy dependence of detergent resistance in Enterobacter cloacae: a likely requirement for ATP rather than a proton gradient or a membrane potential. | 1994 | Can. J. Microbiol. | pmid:8012906 |
| Harada T and Mino Y | Some properties of p-coumarate decarboxylase from Cladosporium phlei. | 1976 | Can. J. Microbiol. | pmid:10068 |
| Markowitz S et al. | Enhancement and inhibition of phagocytic activity in the retinal pigment epithelium. | 1981 | Can. J. Ophthalmol. | pmid:7344763 |
| Goldhar SW et al. | Phagocytosis by retinal pigment epithelium: evaluation of modulating agents with an organ culture model. | 1984 | Can. J. Ophthalmol. | pmid:6713267 |
| Chan CB et al. | Evidence for defective glucose sensing by islets of fa/fa obese Zucker rats. | 1993 | Can. J. Physiol. Pharmacol. | pmid:8513432 |
| Goodyer AV | The abnormal mechanical strength-interval curve of hypoxic rabbit papillary muscle. | 1988 | Can. J. Physiol. Pharmacol. | pmid:3214803 |
| Perks AM et al. | Lung liquid production by in vitro lungs from fetal guinea pigs: studies with metabolic inhibitors. | 1991 | Can. J. Physiol. Pharmacol. | pmid:1756423 |
| Rosenthal M and Sick TJ | Glycolytic and oxidative metabolic contributions to potassium ion transport in rat cerebral cortex. | 1992 | Can. J. Physiol. Pharmacol. | pmid:1295667 |
| Mainwood GW et al. | The effects of metabolic inhibitors on the contraction of creatine-depleted muscle. | 1982 | Can. J. Physiol. Pharmacol. | pmid:7083060 |
| Perks AM et al. | Reabsorption of lung liquid produced by 2,4-dinitrophenol in in vitro lungs from fetal guinea pigs. | 1993 | Can. J. Physiol. Pharmacol. | pmid:8390326 |
| Penraat JH et al. | An evaluation of chemical arthrodesis of the proximal interphalangeal joint in the horse by using monoiodoacetate. | 2000 | Can. J. Vet. Res. | pmid:11041498 |
| Trotter GW et al. | Effects of intramuscular polysulfated glycosaminoglycan on chemical and physical defects in equine articular cartilage. | 1989 | Can. J. Vet. Res. | pmid:2469533 |
| HOMBURGER F and PFEIFFER PH | Evaluation of diagnostic tests for cancer; inhibition of thermal coagulation of serum by iodoacetic acid, the Huggins-Miller-Jensen test. | 1950 | Cancer | pmid:15405677 |
| Yang D et al. | Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L). | 2010 | Cancer Biol. Ther. | pmid:19923925 |
| Vial D et al. | Coordinate regulation of fibronectin matrix assembly by the plasminogen activator system and vitronectin in human osteosarcoma cells. | 2006 | Cancer Cell Int. | pmid:16569238 |
| Parfett CL | Induction of proliferin gene expression by diverse chemical agents that promote morphological transformation in C3H/10T1/2 cultures. | 1992 | Cancer Lett. | pmid:1596871 |
| Pan SS et al. | Mechanism of transport and intracellular binding of porfiromycin in HCT 116 human colon carcinoma cells. | 1989 | Cancer Res. | pmid:2766276 |
| Rheins MS et al. | Effect of iodoacetate on the bone marrow immunocompetence of AKR mice. | 1975 | Cancer Res. | pmid:1093673 |
| Paffenholz V et al. | Uptake of partially thiolated DNA by ascites tumor cells. | 1976 | Cancer Res. | pmid:944094 |
| Ito E et al. | Effects of 2,4-dinitrophenol and other metabolic inhibitors on the thermograms of Ehrlich ascites carcinoma cells registered with a microcalorimeter. | 1984 | Cancer Res. | pmid:6713397 |
| Hilf R et al. | Relationship of mitochondrial function and cellular adenosine triphosphate levels to hematoporphyrin derivative-induced photosensitization in R3230AC mammary tumors. | 1986 | Cancer Res. | pmid:3940191 |
| Kensler TW and Trush MA | Inhibiton of phorbol ester-stimulated chemiluminescence in human polymorphonuclear leukocytes by retinoic acid and 5,6-epoxyretinoic acid. | 1981 | Cancer Res. | pmid:6256061 |
| Yoshida C et al. | Purification and properties of inorganic pyrophosphatase of rat liver and hepatoma 3924A. | 1982 | Cancer Res. | pmid:6125258 |
| Kunz BA et al. | Effect of tumor promoters on ultraviolet light-induced mutation and mitotic recombination in Saccharomyces cerevisiae. | 1980 | Cancer Res. | pmid:6992984 |
| Ide T et al. | Recovery of a DNA-protein complex in cultured mammalian cells from damage caused by 4-nitroquinoline 1-oxide. | 1975 | Cancer Res. | pmid:810243 |
| Thiry L et al. | Comparison of the immunogenicity of hamster cells transformed by adenovirus and Herpes simplex virus. | 1975 | Cancer Res. | pmid:163694 |
| Andrews PA et al. | cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells. | 1988 | Cancer Res. | pmid:3335000 |
| Shao H et al. | Intra-articular injection of xanthan gum reduces pain and cartilage damage in a rat osteoarthritis model. | 2013 | Carbohydr Polym | pmid:23399228 |
| Collard WT et al. | Synthesis of homogeneous glycopeptides and their utility as DNA condensing agents. | 2000 | Carbohydr. Res. | pmid:10782299 |
| Mason RM and Sweeney C | The relationship between proteoglycan synthesis in Swarm chondrocytes and pathways of cellular energy and UDP-sugar metabolism. | 1994 | Carbohydr. Res. | pmid:8181010 |
| Cherif-Zahar C et al. | Tumor promoters enhance cap formation in mouse thymocytes. | 1983 | Carcinogenesis | pmid:6600416 |
| Kinsella AR | Elimination of metabolic co-operation and the induction of sister chromatid exchanges are not properties common to all promoting or co-carcinogenic agents. | 1982 | Carcinogenesis | pmid:7094211 |
| MacArthur CA et al. | Chemical carcinogens induce cadmium resistance and activate metallothionein genes in cadmium sensitive S49 mouse cells. | 1985 | Carcinogenesis | pmid:3874005 |
| Bloom HL et al. | Statins Decrease Oxidative Stress and ICD Therapies. | 2010 | Cardiol Res Pract | pmid:20369058 |
| Huisamen B et al. | Signalling pathways activated by glucagon-like peptide-1 (7-36) amide in the rat heart and their role in protection against ischaemia. | 2008 Mar-Apr | Cardiovasc J Afr | pmid:18516352 |
| Pirolo JS and Allen DG | Assessment of techniques for preventing glycolysis in cardiac muscle. | 1986 | Cardiovasc. Res. | pmid:3621285 |
| Rodrigo GC and Standen NB | Role of mitochondrial re-energization and Ca2+ influx in reperfusion injury of metabolically inhibited cardiac myocytes. | 2005 | Cardiovasc. Res. | pmid:15885675 |
| Siflinger A et al. | Uptake of 125I albumin by the endothelial surface of the isolated dog common carotid artery: effect of certain physical factors and metabolic inhibitors. | 1975 | Cardiovasc. Res. | pmid:1182724 |
| Braunlin EA et al. | Myoglobin facilitated oxygen diffusion maintains mechanical function of mammalian cardiac muscle. | 1986 | Cardiovasc. Res. | pmid:3791352 |
| Armstrong S and Ganote CE | Preconditioning of isolated rabbit cardiomyocytes: effects of glycolytic blockade, phorbol esters, and ischaemia. | 1994 | Cardiovasc. Res. | pmid:7842465 |
| Ziegelstein RC et al. | Increase in rat aortic endothelial free calcium mediated by metabolically sensitive calcium release from endoplasmic reticulum. | 1994 | Cardiovasc. Res. | pmid:7954656 |
| Lee JA and Allen DG | Comparison of the effects of inotropic interventions on isometric tension and shortening in isolated ferret ventricular muscle. | 1989 | Cardiovasc. Res. | pmid:2611813 |
| Senges J et al. | Metabolism and the electrical activity of human atrial myocardium. | 1981 | Cardiovasc. Res. | pmid:7296589 |
| Ganote CE et al. | Adenosine and A1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes. | 1993 | Cardiovasc. Res. | pmid:8287447 |
| Galzigna L et al. | Some effects of fructose-1,6-diphosphate on rat myocardial tissue related to a membrane-stabilizing action. | 1989 | Cell Biochem. Funct. | pmid:2548756 |
| Eaton BM et al. | Uptake of alpha 2-macroglobulin-trypsin complex by human placenta is mediated by a microvillous membrane receptor. | 1989 | Cell Biochem. Funct. | pmid:2473854 |
| Ivannikov MV et al. | Calcium clearance and its energy requirements in cerebellar neurons. | 2010 | Cell Calcium | pmid:20510449 |
| Nieminen AL et al. | Calcium dependence of bleb formation and cell death in hepatocytes. | 1988 | Cell Calcium | pmid:3224370 |
| Borle AB and Barsic M | Chemical hypoxia increases cytosolic Ca2+ and oxygen free radical formation. | 1995 | Cell Calcium | pmid:7664318 |
| Korohoda W et al. | Energy metabolic regulation of oscillatory contraction activity in Physarum polycephalum. | 1983 | Cell Tissue Res. | pmid:6871978 |
| Yoshikai Y et al. | The suppressive effect of peritoneal exudate macrophages on production of antibody to sheep erythrocytes in vitro. | 1983 | Cell. Immunol. | pmid:6573972 |
| Correa F et al. | Post-conditioning preserves glycolytic ATP during early reperfusion: a survival mechanism for the reperfused heart. | 2008 | Cell. Physiol. Biochem. | pmid:19088445 |
| Wei Y et al. | Transient Receptor Potential Vanilloid 5 Mediates Ca2+ Influx and Inhibits Chondrocyte Autophagy in a Rat Osteoarthritis Model. | 2017 | Cell. Physiol. Biochem. | pmid:28535500 |
| Liu Y et al. | Activation of α7 nicotinic acetylcholine receptors prevents monosodium iodoacetate-induced osteoarthritis in rats. | 2015 | Cell. Physiol. Biochem. | pmid:25613062 |
| Tůmová L et al. | [Iodoacetic acid as a potential elicitor of increased production of flavonoids in a culture of Ononis arvensis L. in vitro]. | 2003 | Ceska Slov Farm | pmid:12924071 |
| Ulanovskaya OA et al. | A pairwise chemical genetic screen identifies new inhibitors of glucose transport. | 2011 | Chem. Biol. | pmid:21338919 |
| Nakamura K et al. | Detoxification system for inorganic arsenic: transformation of As2O3 into TMAO by vitamin B12 derivatives and conversion of TMAO into arsenobetaine. | 2008 | Chem. Commun. (Camb.) | pmid:18956042 |
| Procházka E et al. | In Vitro Cytotoxicity and Adaptive Stress Responses to Selected Haloacetic Acid and Halobenzoquinone Water Disinfection Byproducts. | 2015 | Chem. Res. Toxicol. | pmid:26327680 |
| Jean PA and Reed DJ | In vitro dipeptide, nucleoside, and glutathione alkylation by S-(2-chloroethyl)glutathione and S-(2-chloroethyl)-L-cysteine. | 1989 Nov-Dec | Chem. Res. Toxicol. | pmid:2519737 |
| Akhter Hossain M et al. | Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5). | 2008 | Chembiochem | pmid:18576448 |
| Bhattacharjee S et al. | Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation. | 2015 | Chembiochem | pmid:26481301 |
| Qiao YL | [Perspective of cervical cancer prevention and control in developing countries and areas]. | 2010 | Chin J Cancer | pmid:20038301 |
| Dekker LR et al. | Intracellular Ca2+, intercellular electrical coupling, and mechanical activity in ischemic rabbit papillary muscle. Effects of preconditioning and metabolic blockade. | 1996 | Circ. Res. | pmid:8756000 |
| Coetzee WA and Opie LH | Effects of components of ischemia and metabolic inhibition on delayed afterdepolarizations in guinea pig papillary muscle. | 1987 | Circ. Res. | pmid:3621482 |
| Haworth RA et al. | Inhibition of calcium influx in isolated adult rat heart cells by ATP depletion. | 1987 | Circ. Res. | pmid:3594742 |
| Lee SL and Fanburg BL | Glycolytic activity and enhancement of serotonin uptake by endothelial cells exposed to hypoxia/anoxia. | 1987 | Circ. Res. | pmid:3594745 |
| Yin FC et al. | Age-associated alterations in viscoelastic properties of canine aortic strips. | 1983 | Circ. Res. | pmid:6627606 |
| Buja LM et al. | Characterization of a potentially reversible increase in beta-adrenergic receptors in isolated, neonatal rat cardiac myocytes with impaired energy metabolism. | 1985 | Circ. Res. | pmid:2994904 |
| Rasio EA et al. | Effect of reduced energy metabolism and reperfusion on the permeability and morphology of the capillaries of an isolated rete mirabile. | 1989 | Circ. Res. | pmid:2912596 |
| Geisbuhler T et al. | Adenine nucleotide metabolism and compartmentalization in isolated adult rat heart cells. | 1984 | Circ. Res. | pmid:6373048 |
| Webster KA et al. | Regulation of fos and jun immediate-early genes by redox or metabolic stress in cardiac myocytes. | 1994 | Circ. Res. | pmid:8137504 |
| Wagner DR et al. | Existence and role of substrate cycling between AMP and adenosine in isolated rabbit cardiomyocytes under control conditions and in ATP depletion. | 1994 | Circulation | pmid:8087944 |
| Lee JH et al. | Alteration patterns of trabecular bone microarchitectural characteristics induced by osteoarthritis over time. | 2012 | Clin Interv Aging | pmid:22956865 |
| Dubois JA et al. | The effect of specimen collection additives and sample storage on the Dupont ACA glucose method. | 1982 | Clin. Biochem. | pmid:6807570 |
| Bazzocco S et al. | Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment. | 2015 | Clin. Cancer Res. | pmid:25944804 |
| Meites S and Saniel-Banrey K | Preservation, distribution, and assay of glucose in blood, with special reference to the newborn. | 1979 | Clin. Chem. | pmid:466761 |
| Mortensen E | Effect of storage on the apparent concentration of folate in erythrocytes, as measured by competitive protein binding radioassay. | 1978 | Clin. Chem. | pmid:639272 |
| Marbach EP et al. | Sodium iodoacetate as an antiglycolytic agent in blood samples. | 1975 | Clin. Chem. | pmid:1183004 |
| Robertson EA et al. | Serum collected with lithium iodoacetate is unsuitable for electrolyte and lactate dehydrogenase measurements. | 1980 | Clin. Chem. | pmid:7389098 |