| MeSH term | MeSH ID | Detail |
|---|---|---|
| Temporomandibular Joint Disorders | D013705 | 4 associated lipids |
| Arthralgia | D018771 | 8 associated lipids |
| Osteophyte | D054850 | 2 associated lipids |
| Glycogen Storage Disease | D006008 | 4 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Retinitis | D012173 | 4 associated lipids |
| Theileriasis | D013801 | 7 associated lipids |
| Muscle Cramp | D009120 | 3 associated lipids |
| Rigor Mortis | D012298 | 1 associated lipids |
| Thrombophilia | D019851 | 6 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sato S et al. | [Effects of sodium iodate, iodoacetic acid and ethambutol on electroretinogram and visual evoked potential in rats]. | 1984 | J Toxicol Sci | pmid:6527394 |
| Sugimoto S et al. | [A procedure for electroretinogram (ERG) recording in mice--effect of monoiodoacetic acid on the ERG in pigmented mice]. | 1997 | J Toxicol Sci | pmid:9430091 |
| Yamairi F et al. | Expression of vascular endothelial growth factor (VEGF) associated with histopathological changes in rodent models of osteoarthritis. | 2011 | J Toxicol Pathol | pmid:22272053 |
| Takada S et al. | Comparison of lesions induced by intra-articular injections of quinolones and compounds damaging cartilage components in rat femoral condyles. | 1994 | J Toxicol Environ Health | pmid:7513367 |
| Fiaschi T et al. | Redox Regulation of Nonmuscle Myosin Heavy Chain during Integrin Engagement. | 2012 | J Signal Transduct | pmid:22220276 |
| Weinbaum DL et al. | Human neutrophil membrane topography: examination of distribution, movement, and regeneration of recognition sites using lectins as probes. | 1983 | J Reticuloendothel Soc | pmid:6834362 |
| Selvaraj RJ et al. | A microtechnique for studying chemiluminescence response of phagocytes using whole blood and its application to the evaluation of phagocytes in pregnancy. | 1982 | J Reticuloendothel Soc | pmid:7062313 |
| Shirran SL and Botting CH | A comparison of the accuracy of iTRAQ quantification by nLC-ESI MSMS and nLC-MALDI MSMS methods. | 2010 | J Proteomics | pmid:20230925 |
| Park JY et al. | Physical model approach to gastrointestinal absorption of prostaglandins II: In situ rat intestinal absorption of dinoprost. | 1984 | J Pharm Sci | pmid:6596427 |
| Aiedeh KM et al. | Effect of ionic crosslinking on the drug release properties of chitosan diacetate matrices. | 2007 | J Pharm Sci | pmid:17031867 |
| Volate S et al. | TJ-41 Induces Apoptosis and Potentiates the Apoptotic Effects of 5-FU in Breast Cancer Cell Lines. | 2009 | J Oncol | pmid:19710936 |
| Meesawatsom P et al. | Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models. | 2016 | J Neuroinflammation | pmid:27589850 |
| Garfield RE and Daniel EE | Relation of membrane vesicles to volume and Na+ transport in smooth muscle: effect of metabolic and transport inhibition on fresh tissues. | 1977 | J Mechanochem Cell Motil | pmid:157383 |
| Lapko VN et al. | Identification of an artifact in the mass spectrometry of proteins derivatized with iodoacetamide. | 2000 | J Mass Spectrom | pmid:10797654 |
| Brown KK et al. | P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis. | 2008 | J Inflamm (Lond) | pmid:19055838 |
| Tong P et al. | Chondroprotective activity of a detoxicated traditional Chinese medicine (Fuzi) of Aconitum carmichaeli Debx against severe-stage osteoarthritis model induced by mono-iodoacetate. | 2014 | J Ethnopharmacol | pmid:24315981 |
| Milner MJ and Sang JH | Active ion transport and beta-acdysone induced differentiation of Drosophila melanogaster imaginal discs cultured in vitro. | 1977 | J Embryol Exp Morphol | pmid:404384 |
| Brunton LL and Buss JE | Export of cyclic AMP by mammalian reticulocytes. | 1980 | J Cyclic Nucleotide Res | pmid:6260842 |
| Sintov AC et al. | Cutaneous biotransformation of N-(4-bromobenzoyl)-S,S-dimethyliminosulfurane and its product, 4-bromobenzamide, leading to percutaneous penetration enhancement of drugs: initial evidence using hydrocortisone. | 2009 | J Control Release | pmid:18950667 |
| Li Y et al. | Analysis of iodinated haloacetic acids in drinking water by reversed-phase liquid chromatography/electrospray ionization/tandem mass spectrometry with large volume direct aqueous injection. | 2012 | J Chromatogr A | pmid:22658134 |
| Chu CR et al. | In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage. | 2010 | J Bone Joint Surg Am | pmid:20194318 |
| Mercier P et al. | Elaboration of neutral proteoglycanase by growth-plate tissue cultures. | 1987 | J Bone Joint Surg Am | pmid:3100539 |
| Kelly MJ and Richardson W | Possible mechanisms for the protective action of alpha-tocopherol in vascular hypoxia. | 1996 | J Auton Pharmacol | pmid:8842869 |
| Stockwell PB | Abstracts of papers presented at the 2008 pittsburgh conference. | 2008 | J Autom Methods Manag Chem | pmid:19365566 |
| Wormser U et al. | Protective effect of povidone iodine ointment against skin lesions induced by chemical and thermal stimuli. | 2000 | J Appl Toxicol | pmid:11428633 |
| Ahammad Sahib KI et al. | Effects of methyl mercury and cadmium on the kinetics of substrate activation of (K+)-paranitrophenyl phosphatase. | 1987 | J Appl Toxicol | pmid:2442238 |
| Lussier LM et al. | Human alveolar macrophages: antigen-independent binding of lymphocytes. | 1978 | J Appl Physiol Respir Environ Exerc Physiol | pmid:365839 |
| Stanbrook HS and McMurtry IF | Inhibition of glycolysis potentiates hypoxic vasoconstriction in rat lungs. | 1983 | J Appl Physiol Respir Environ Exerc Physiol | pmid:6643184 |
| Montanaro L et al. | A metalloproteinase associated with gelonin, a "ribosome inactivating protein". | 1985 Jan-Feb | Ital. J. Biochem. | pmid:3924857 |
| Yoshida A | Differences in the isozymes involved in alcohol metabolism between caucasians and orientals. | 1983 | Isozymes Curr. Top. Biol. Med. Res. | pmid:6354999 |
| Newsome DA and Rothman RJ | Zinc uptake in vitro by human retinal pigment epithelium. | 1987 | Invest. Ophthalmol. Vis. Sci. | pmid:3667151 |
| Ashburn FS et al. | The effects of iodate and iodoacetate on the retinal adhesion. | 1980 | Invest. Ophthalmol. Vis. Sci. | pmid:7440100 |
| Yamamoto F and Honda Y | Effects of intravenous iodoacetate and iodate on pH outside rod photoreceptors in the cat retina. | 1993 | Invest. Ophthalmol. Vis. Sci. | pmid:8491551 |
| Matsumoto B and Besharse JC | Light and temperature modulated staining of the rod outer segment distal tips with Lucifer yellow. | 1985 | Invest. Ophthalmol. Vis. Sci. | pmid:2581915 |
| Winkler BS et al. | Energy metabolism in human retinal Müller cells. | 2000 | Invest. Ophthalmol. Vis. Sci. | pmid:10967082 |
| Farber DB et al. | Cyclic nucleotides of cone-dominant retinas. Reduction of cyclic AMP levels by light and by cone degeneration. | 1981 | Invest. Ophthalmol. Vis. Sci. | pmid:6256308 |
| Farber DB et al. | Cone visual cell degeneration in ground squirrel retina: disruption of morphology and cyclic nucleotide metabolism by lodoacetic acid. | 1983 | Invest. Ophthalmol. Vis. Sci. | pmid:6885310 |
| David LL and Shearer TR | Calcium-activated proteolysis in the lens nucleus during selenite cataractogenesis. | 1984 | Invest. Ophthalmol. Vis. Sci. | pmid:6386740 |
| Opas M et al. | Effects of iodoacetic acid on cytoskeleton and adhesiveness of the chick RPE cells in vitro. | 1986 | Invest. Ophthalmol. Vis. Sci. | pmid:3087905 |
| Parmelee JT et al. | Effects of calcium on the steady outward currents at the equator of the rat lens. | 1985 | Invest. Ophthalmol. Vis. Sci. | pmid:4044162 |
| Edwards RB | Accumulation of taurine by cultured retinal pigment epithelium of the rat. | 1977 | Invest. Ophthalmol. Vis. Sci. | pmid:844977 |
| Wang W et al. | Selective rod degeneration and partial cone inactivation characterize an iodoacetic acid model of Swine retinal degeneration. | 2011 | Invest. Ophthalmol. Vis. Sci. | pmid:21896868 |
| Stone RA and Wilson CM | Fluorescein transport in the anterior uvea. | 1982 | Invest. Ophthalmol. Vis. Sci. | pmid:7061203 |
| Dobbs PC et al. | Identification of isoenzyme C as the principal carbonic anhydrase in human ciliary processes. | 1979 | Invest. Ophthalmol. Vis. Sci. | pmid:110725 |
| Pacchiarini L et al. | Thromboxane production by platelets during tumor cell-induced platelet activation. | 1991 | Invasion Metastasis | pmid:1917383 |
| Pacchiarini L et al. | Role of tumor proteinases in tumor cell-induced platelet aggregation. | 1986 | Invasion Metastasis | pmid:3536793 |
| Grignani G et al. | Mechanisms of platelet activation by cultured human cancer cells and cells freshly isolated from tumor tissues. | 1989 | Invasion Metastasis | pmid:2767927 |
| Purohit SC et al. | Structural modification of human erythrocyte membranes following gamma-irradiation. | 1980 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:6776069 |
| Noguti T et al. | Radiosensitization with iodine compounds. 3. Macromolecular synthesis and repair in Bacillus subtilis irradiated in the presence of iodoacetic acid, potassium iodide or potassium iodate. | 1971 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:4995962 |
| Purohit SC et al. | Chemical damage in gamma-irradiated human erythrocyte membranes. | 1980 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:6968734 |
| Palcic B and Skarsgard LD | Absence of ultrafast processes of repair of single-strand breaks in mammalian DNA. | 1975 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:804459 |
| Nair CK and Pradhan DS | Production and rejoining of single-strand breaks in DNA of Escherichia coli cells after exposure to gamma-rays in the presence of iodoacetic acid under oxic and anoxic conditions. | 1976 | Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. | pmid:773873 |
| Gaehde SA and Matsueda GR | Synthesis of N-tert.-butoxycarbonyl-( alpha-phenyl)aminomethylphenoxyacetic acid for use as a handle in solid-phase synthesis of peptide alpha-carboxamides. | 1981 | Int. J. Pept. Protein Res. | pmid:7341527 |
| Estrada P et al. | Mechanism of the reaction catalyzed by acyl-CoA: lysolecithin acyltransferase from rabbit lung. pH studies and chemical modification. | 1985 | Int. J. Pept. Protein Res. | pmid:4019033 |
| Lu HS et al. | Human urinary kallikrein. Complete amino acid sequence and sites of glycosylation. | 1989 | Int. J. Pept. Protein Res. | pmid:2666327 |
| Bergenhem N et al. | Evidence for an initial fast nucleation process in the folding of human carbonic anhydrase I. | 1989 | Int. J. Pept. Protein Res. | pmid:2496046 |
| Reisin IL et al. | Water and electrolyte balance in protoscoleces of Echinococcus granulosus incubated in vitro: effect of metabolic inhibitors. | 1981 | Int. J. Parasitol. | pmid:7309342 |
| Sethi R et al. | Characteristics and mechanisms of tachyphylaxis of cardiac contractile response to insulin. | 1993 | Int. J. Cardiol. | pmid:8454373 |
| Takada K and Zur Hausen H | Induction of Epstein-Barr virus antigens by tumor promoters for epidermal and nonepidermal tissues. | 1984 | Int. J. Cancer | pmid:6323326 |
| Grignani G et al. | Human breast and colon carcinomas express cysteine proteinase activities with pro-aggregating and pro-coagulant properties. | 1988 | Int. J. Cancer | pmid:3170028 |
| RodrÃguez E et al. | Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. | 2010 | Int. J. Biol. Sci. | pmid:20440403 |
| De Busser HM et al. | Identification of prenylcysteine carboxymethyltransferase in bovine adrenal chromaffin cells. | 2000 | Int. J. Biochem. Cell Biol. | pmid:11084380 |
| Koekemoer TC et al. | Isolation and characterization of adipose tissue glycerol-3-phosphate dehydrogenase. | 1995 | Int. J. Biochem. Cell Biol. | pmid:7671141 |
| Campbell CJ and Park MV | The role of the available sulphydryl group in liver butyryl-coenzyme A synthetase. | 1987 | Int. J. Biochem. | pmid:3609444 |
| Batra PP et al. | Circular dichroic study of the conformational stability of sulfhydryl-blocked bovine serum albumin. | 1989 | Int. J. Biochem. | pmid:2583353 |
| Grossman S and Waksman EG | New aspects of the inhibition of soybean lipoxygenase by alpha-tocopherol. Evidence for the existence of a specific complex. | 1984 | Int. J. Biochem. | pmid:6421635 |
| Smith JJ et al. | Metabolic energy and cytoskeletal requirements for synthesis and secretion by acini from rat mammary gland-I. Ultrastructural and biochemical aspects of synthesis and release of milk proteins. | 1982 | Int. J. Biochem. | pmid:7200042 |
| Smith JJ et al. | Metabolic energy and cytoskeletal requirements for synthesis and secretion by acini from rat mammary gland-II. Intracellular transport and secretion of protein and lactose. | 1982 | Int. J. Biochem. | pmid:7067894 |
| Dumitru IF and Dinischiotu A | Cock seminal plasma acid phosphatase: active site directed inactivation, crystallization and in vitro denaturation-renaturation studies. | 1994 | Int. J. Biochem. | pmid:8013734 |
| Walker JR and Parish HA | Metabolic requirements for rabbit polymorphonuclear leucocyte lipoxygenase activity. | 1981 | Int. Arch. Allergy Appl. Immunol. | pmid:6266969 |
| Cook RM and Moran DM | Accessory cell response to rye grass pollen extract in mice, guinea pigs and man. | 1984 | Int. Arch. Allergy Appl. Immunol. | pmid:6198292 |
| Siegel I et al. | Fc- and complement-receptor rosette-forming cell ratios in human tonsils and peripheral blood. | 1976 | Int. Arch. Allergy Appl. Immunol. | pmid:814104 |
| Saba J et al. | Increasing the productivity of glycopeptides analysis by using higher-energy collision dissociation-accurate mass-product-dependent electron transfer dissociation. | 2012 | Int J Proteomics | pmid:22701174 |
| Kwok KY et al. | Strategies for maintaining the particle size of peptide DNA condensates following freeze-drying. | 2000 | Int J Pharm | pmid:10967430 |
| Trivedi M et al. | Improving the stability of the EC1 domain of E-cadherin by thiol alkylation of the cysteine residue. | 2012 | Int J Pharm | pmid:22531851 |
| Chiu PR et al. | Vitamin C Protects Chondrocytes against Monosodium Iodoacetate-Induced Osteoarthritis by Multiple Pathways. | 2016 | Int J Mol Sci | pmid:28035982 |
| Matsuura K et al. | Syntheses and self-assembling behaviors of pentagonal conjugates of tryptophane zipper-forming peptide. | 2011 | Int J Mol Sci | pmid:21954352 |
| Naveen SV et al. | Histology, glycosaminoglycan level and cartilage stiffness in monoiodoacetate-induced osteoarthritis: comparative analysis with anterior cruciate ligament transection in rat model and human osteoarthritis. | 2014 | Int J Med Sci | pmid:24396291 |
| Dunham J et al. | Structural and metabolic changes in articular cartilage induced by iodoacetate. | 1992 | Int J Exp Pathol | pmid:1390193 |
| Dunham J et al. | Prolonged effect of iodoacetate on articular cartilage and its modification by an anti-rheumatic drug. | 1993 | Int J Exp Pathol | pmid:8334078 |
| Khanna SK et al. | Studies on the skin uptake and efflux kinetics of N-phenyl-p-phenylenediamine: an aromatic amine intermediate. | 1987 | Int J Cosmet Sci | pmid:19456976 |
| Taniguchi A et al. | Decreased calcitonin gene-related peptide expression in the dorsal root ganglia of TNF-deficient mice in a monoiodoacetate-induced knee osteoarthritis model. | 2015 | Int J Clin Exp Pathol | pmid:26722492 |
| Glander HJ and Haustein UF | The influence of the cryopreserving process on rubidium uptake by human spermatozoa. | 1982 | Int J Biol Res Pregnancy | pmid:7076340 |
| Brody KR and Spencer RP | Distribution and decarboxylation of 1- 14 C-iodoacetic acid in dogs. | 1972 | Int J Appl Radiat Isot | pmid:5080821 |
| Parkinson AJ and Kalmakoff J | Tritium labeling of immunoglobulin with iodoacetic acid. | 1975 Jun-Jul | Int J Appl Radiat Isot | pmid:1237470 |
| Van Epps DE et al. | Casein-mediated neutrophil chemotaxis: a parallel between surface binding and chemotaxis. | 1977 | Inflammation | pmid:617803 |
| Smith RJ and Iden SS | Properties of calcium ionophore-induced generation of superoxide anion by human neutrophils. | 1981 | Inflammation | pmid:6271675 |
| Sugarman B et al. | Zinc and bacterial adherence. | 1982 | Infect. Immun. | pmid:6127314 |
| Mapother ME and Songer JG | In vitro interaction of Mycobacterium avium with intestinal epithelial cells. | 1984 | Infect. Immun. | pmid:6329959 |
| Stinson MW et al. | Inhibition of Porphyromonas gingivalis adhesion to Streptococcus gordonii by human submandibular-sublingual saliva. | 1992 | Infect. Immun. | pmid:1319402 |
| Pattnaik S et al. | L-asparaginase activity in Aeromonas sp. isolated from freshwater mussel. | 2000 | Indian J. Exp. Biol. | pmid:11395960 |
| Kaur S et al. | Effect of pH and sodium ions on intestinal uptake of lysine in rats. | 1993 | Indian J. Exp. Biol. | pmid:8406600 |
| Kagawa S et al. | Maintenance of pancreatic endocrine cells of the neonatal rat: Part XIII--Effect of 2-deoxyglucose and iodoacetic acid on the functional maturation of neonatal rat B cells. | 1988 | Indian J. Biochem. Biophys. | pmid:3072288 |
| Liang L et al. | Purification and characterization of trehalose-6-phosphate synthase from Saccharomycopsis fibuligera A11. | 2006 | Indian J. Biochem. Biophys. | pmid:17133735 |
| Kagawa S et al. | Maintenance of pancreatic endocrine cells of the neonatal rat: Part XII--Development of the response by infant rat pancreatic monolayer-cultured B cells. | 1987 | Indian J. Biochem. Biophys. | pmid:3329630 |
| Buja LM et al. | Altered membrane fluidity occurs during metabolic impairment of cardiac myocytes. | 1991 May-Jun | In Vivo | pmid:1893080 |
| Gilmour KM et al. | Transepithelial potential of cultured branchial epithelia from rainbow trout under symmetrical conditions. | 1998 | In Vitro Cell. Dev. Biol. Anim. | pmid:9661043 |
| Flagg-Newton JL | The permeability of the cell-to-cell membrane channel and its regulation in mammalian cell junctions. | 1980 | In Vitro | pmid:6260623 |
| Marden LL et al. | Depletion and recovery of ATP in V79 cells with exposure to inhibitors of glycolysis and oxidative phosphorylation. | 1982 | In Vitro | pmid:7118135 |
| Filppi JA et al. | Effect of iodoacetate on T lymphocytes of young AKR mice. | 1977 | Immunology | pmid:303612 |