Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Temporomandibular Joint Disorders D013705 4 associated lipids
Arthralgia D018771 8 associated lipids
Osteophyte D054850 2 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Retinitis D012173 4 associated lipids
Theileriasis D013801 7 associated lipids
Muscle Cramp D009120 3 associated lipids
Rigor Mortis D012298 1 associated lipids
Thrombophilia D019851 6 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Maekawa Y et al. A tetrazolium-based colorimetric assay for metabolic activity of stored blood platelets. 2003 Thromb. Res. pmid:12818255
Flanagan PR and Zbarsky SH Rat intestinal phosphodiesterase II. Properties of the highly purified enzyme and its inactivation by iodoacetic acid. 1977 Biochim. Biophys. Acta pmid:12824
Kim YJ Partial inhibition of biohydrogenation of linoleic acid can increase the conjugated linoleic acid production of Butyrivibrio fibrisolvens A38. 2003 J. Agric. Food Chem. pmid:12848494
Ding PZ An investigation of cysteine mutants on the cytoplasmic loop X/XI in the melibiose transporter of Escherichia coli by using thiol reagents: implication of structural conservation of charged residues. 2003 Biochem. Biophys. Res. Commun. pmid:12878191
pmid:12882641
Massieu L et al. Acetoacetate protects hippocampal neurons against glutamate-mediated neuronal damage during glycolysis inhibition. 2003 Neuroscience pmid:12890508
pmid:12892929
Bürkert E et al. The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1. 2003 J. Biol. Chem. pmid:12893830
Chen X et al. [Detection of proteolytic activity of hepatitis C virus NS3-4A protease using enzymelinked immunosorbent assay]. 2000 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:12903484
Vera PL and Meyer-Siegler KL Anatomical location of macrophage migration inhibitory factor in urogenital tissues, peripheral ganglia and lumbosacral spinal cord of the rat. 2003 BMC Neurosci pmid:12908877
Tůmová L et al. [Iodoacetic acid as a potential elicitor of increased production of flavonoids in a culture of Ononis arvensis L. in vitro]. 2003 Ceska Slov Farm pmid:12924071
pmid:12952458
Rosenthal M and Sick TJ Glycolytic and oxidative metabolic contributions to potassium ion transport in rat cerebral cortex. 1992 Can. J. Physiol. Pharmacol. pmid:1295667
EBE M Effect of glutamic acid, NaCN and monoiodoacetic acid on the potential changes of isolated toad's brain. 1952 Tohoku J. Exp. Med. pmid:13005477
Hruz PW and Miziorko HM Avian 3-hydroxy-3-methylglutaryl-CoA lyase: sensitivity of enzyme activity to thiol/disulfide exchange and identification of proximal reactive cysteines. 1992 Protein Sci. pmid:1304393
Xia Y et al. Oxidative and glycolytic pathways in rat (newborn and adult) and turtle brain: role during anoxia. 1992 Am. J. Physiol. pmid:1314516
Stinson MW et al. Inhibition of Porphyromonas gingivalis adhesion to Streptococcus gordonii by human submandibular-sublingual saliva. 1992 Infect. Immun. pmid:1319402
Rae AS and Strickland KP Studies on phosphate transport in Escherichia coli. II. Effects of metabolic inhibitors and divalent cations. 1976 Biochim. Biophys. Acta pmid:132192
Knowles MR et al. Bovine inositol monophosphatase. Modification, identification and mutagenesis of reactive cysteine residues. 1992 Biochem. J. pmid:1322134
pmid:13248903