Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Temporomandibular Joint Disorders D013705 4 associated lipids
Arthralgia D018771 8 associated lipids
Osteophyte D054850 2 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Retinitis D012173 4 associated lipids
Theileriasis D013801 7 associated lipids
Muscle Cramp D009120 3 associated lipids
Rigor Mortis D012298 1 associated lipids
Thrombophilia D019851 6 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Dekker LR et al. Intracellular Ca2+, intercellular electrical coupling, and mechanical activity in ischemic rabbit papillary muscle. Effects of preconditioning and metabolic blockade. 1996 Circ. Res. pmid:8756000
Coetzee WA and Opie LH Effects of components of ischemia and metabolic inhibition on delayed afterdepolarizations in guinea pig papillary muscle. 1987 Circ. Res. pmid:3621482
Haworth RA et al. Inhibition of calcium influx in isolated adult rat heart cells by ATP depletion. 1987 Circ. Res. pmid:3594742
Lee SL and Fanburg BL Glycolytic activity and enhancement of serotonin uptake by endothelial cells exposed to hypoxia/anoxia. 1987 Circ. Res. pmid:3594745
Yin FC et al. Age-associated alterations in viscoelastic properties of canine aortic strips. 1983 Circ. Res. pmid:6627606
Buja LM et al. Characterization of a potentially reversible increase in beta-adrenergic receptors in isolated, neonatal rat cardiac myocytes with impaired energy metabolism. 1985 Circ. Res. pmid:2994904
Geisbuhler T et al. Adenine nucleotide metabolism and compartmentalization in isolated adult rat heart cells. 1984 Circ. Res. pmid:6373048
Qiao YL [Perspective of cervical cancer prevention and control in developing countries and areas]. 2010 Chin J Cancer pmid:20038301
Akhter Hossain M et al. Synthesis, conformation, and activity of human insulin-like peptide 5 (INSL5). 2008 Chembiochem pmid:18576448
Bhattacharjee S et al. Site-Specific Zwitterionic Polymer Conjugates of a Protein Have Long Plasma Circulation. 2015 Chembiochem pmid:26481301
Procházka E et al. In Vitro Cytotoxicity and Adaptive Stress Responses to Selected Haloacetic Acid and Halobenzoquinone Water Disinfection Byproducts. 2015 Chem. Res. Toxicol. pmid:26327680
Jean PA and Reed DJ In vitro dipeptide, nucleoside, and glutathione alkylation by S-(2-chloroethyl)glutathione and S-(2-chloroethyl)-L-cysteine. 1989 Nov-Dec Chem. Res. Toxicol. pmid:2519737
Nakamura K et al. Detoxification system for inorganic arsenic: transformation of As2O3 into TMAO by vitamin B12 derivatives and conversion of TMAO into arsenobetaine. 2008 Chem. Commun. (Camb.) pmid:18956042
Ulanovskaya OA et al. A pairwise chemical genetic screen identifies new inhibitors of glucose transport. 2011 Chem. Biol. pmid:21338919
Tůmová L et al. [Iodoacetic acid as a potential elicitor of increased production of flavonoids in a culture of Ononis arvensis L. in vitro]. 2003 Ceska Slov Farm pmid:12924071
Correa F et al. Post-conditioning preserves glycolytic ATP during early reperfusion: a survival mechanism for the reperfused heart. 2008 Cell. Physiol. Biochem. pmid:19088445
Wei Y et al. Transient Receptor Potential Vanilloid 5 Mediates Ca2+ Influx and Inhibits Chondrocyte Autophagy in a Rat Osteoarthritis Model. 2017 Cell. Physiol. Biochem. pmid:28535500
Liu Y et al. Activation of α7 nicotinic acetylcholine receptors prevents monosodium iodoacetate-induced osteoarthritis in rats. 2015 Cell. Physiol. Biochem. pmid:25613062
Yoshikai Y et al. The suppressive effect of peritoneal exudate macrophages on production of antibody to sheep erythrocytes in vitro. 1983 Cell. Immunol. pmid:6573972
Korohoda W et al. Energy metabolic regulation of oscillatory contraction activity in Physarum polycephalum. 1983 Cell Tissue Res. pmid:6871978
Ivannikov MV et al. Calcium clearance and its energy requirements in cerebellar neurons. 2010 Cell Calcium pmid:20510449
Nieminen AL et al. Calcium dependence of bleb formation and cell death in hepatocytes. 1988 Cell Calcium pmid:3224370
Borle AB and Barsic M Chemical hypoxia increases cytosolic Ca2+ and oxygen free radical formation. 1995 Cell Calcium pmid:7664318
Galzigna L et al. Some effects of fructose-1,6-diphosphate on rat myocardial tissue related to a membrane-stabilizing action. 1989 Cell Biochem. Funct. pmid:2548756
Eaton BM et al. Uptake of alpha 2-macroglobulin-trypsin complex by human placenta is mediated by a microvillous membrane receptor. 1989 Cell Biochem. Funct. pmid:2473854
Pirolo JS and Allen DG Assessment of techniques for preventing glycolysis in cardiac muscle. 1986 Cardiovasc. Res. pmid:3621285
Rodrigo GC and Standen NB Role of mitochondrial re-energization and Ca2+ influx in reperfusion injury of metabolically inhibited cardiac myocytes. 2005 Cardiovasc. Res. pmid:15885675
Siflinger A et al. Uptake of 125I albumin by the endothelial surface of the isolated dog common carotid artery: effect of certain physical factors and metabolic inhibitors. 1975 Cardiovasc. Res. pmid:1182724
Braunlin EA et al. Myoglobin facilitated oxygen diffusion maintains mechanical function of mammalian cardiac muscle. 1986 Cardiovasc. Res. pmid:3791352
Armstrong S and Ganote CE Preconditioning of isolated rabbit cardiomyocytes: effects of glycolytic blockade, phorbol esters, and ischaemia. 1994 Cardiovasc. Res. pmid:7842465
Ziegelstein RC et al. Increase in rat aortic endothelial free calcium mediated by metabolically sensitive calcium release from endoplasmic reticulum. 1994 Cardiovasc. Res. pmid:7954656
Lee JA and Allen DG Comparison of the effects of inotropic interventions on isometric tension and shortening in isolated ferret ventricular muscle. 1989 Cardiovasc. Res. pmid:2611813
Senges J et al. Metabolism and the electrical activity of human atrial myocardium. 1981 Cardiovasc. Res. pmid:7296589
Ganote CE et al. Adenosine and A1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes. 1993 Cardiovasc. Res. pmid:8287447
Huisamen B et al. Signalling pathways activated by glucagon-like peptide-1 (7-36) amide in the rat heart and their role in protection against ischaemia. 2008 Mar-Apr Cardiovasc J Afr pmid:18516352
Bloom HL et al. Statins Decrease Oxidative Stress and ICD Therapies. 2010 Cardiol Res Pract pmid:20369058
Cherif-Zahar C et al. Tumor promoters enhance cap formation in mouse thymocytes. 1983 Carcinogenesis pmid:6600416
Kinsella AR Elimination of metabolic co-operation and the induction of sister chromatid exchanges are not properties common to all promoting or co-carcinogenic agents. 1982 Carcinogenesis pmid:7094211
MacArthur CA et al. Chemical carcinogens induce cadmium resistance and activate metallothionein genes in cadmium sensitive S49 mouse cells. 1985 Carcinogenesis pmid:3874005
Collard WT et al. Synthesis of homogeneous glycopeptides and their utility as DNA condensing agents. 2000 Carbohydr. Res. pmid:10782299
Mason RM and Sweeney C The relationship between proteoglycan synthesis in Swarm chondrocytes and pathways of cellular energy and UDP-sugar metabolism. 1994 Carbohydr. Res. pmid:8181010
Shao H et al. Intra-articular injection of xanthan gum reduces pain and cartilage damage in a rat osteoarthritis model. 2013 Carbohydr Polym pmid:23399228
Pan SS et al. Mechanism of transport and intracellular binding of porfiromycin in HCT 116 human colon carcinoma cells. 1989 Cancer Res. pmid:2766276
Rheins MS et al. Effect of iodoacetate on the bone marrow immunocompetence of AKR mice. 1975 Cancer Res. pmid:1093673
Paffenholz V et al. Uptake of partially thiolated DNA by ascites tumor cells. 1976 Cancer Res. pmid:944094
Ito E et al. Effects of 2,4-dinitrophenol and other metabolic inhibitors on the thermograms of Ehrlich ascites carcinoma cells registered with a microcalorimeter. 1984 Cancer Res. pmid:6713397
Hilf R et al. Relationship of mitochondrial function and cellular adenosine triphosphate levels to hematoporphyrin derivative-induced photosensitization in R3230AC mammary tumors. 1986 Cancer Res. pmid:3940191
Kensler TW and Trush MA Inhibiton of phorbol ester-stimulated chemiluminescence in human polymorphonuclear leukocytes by retinoic acid and 5,6-epoxyretinoic acid. 1981 Cancer Res. pmid:6256061
Yoshida C et al. Purification and properties of inorganic pyrophosphatase of rat liver and hepatoma 3924A. 1982 Cancer Res. pmid:6125258
Kunz BA et al. Effect of tumor promoters on ultraviolet light-induced mutation and mitotic recombination in Saccharomyces cerevisiae. 1980 Cancer Res. pmid:6992984
Ide T et al. Recovery of a DNA-protein complex in cultured mammalian cells from damage caused by 4-nitroquinoline 1-oxide. 1975 Cancer Res. pmid:810243
Thiry L et al. Comparison of the immunogenicity of hamster cells transformed by adenovirus and Herpes simplex virus. 1975 Cancer Res. pmid:163694
Andrews PA et al. cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells. 1988 Cancer Res. pmid:3335000
Parfett CL Induction of proliferin gene expression by diverse chemical agents that promote morphological transformation in C3H/10T1/2 cultures. 1992 Cancer Lett. pmid:1596871
Vial D et al. Coordinate regulation of fibronectin matrix assembly by the plasminogen activator system and vitronectin in human osteosarcoma cells. 2006 Cancer Cell Int. pmid:16569238
Yang D et al. Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L). 2010 Cancer Biol. Ther. pmid:19923925
HOMBURGER F and PFEIFFER PH Evaluation of diagnostic tests for cancer; inhibition of thermal coagulation of serum by iodoacetic acid, the Huggins-Miller-Jensen test. 1950 Cancer pmid:15405677
Penraat JH et al. An evaluation of chemical arthrodesis of the proximal interphalangeal joint in the horse by using monoiodoacetate. 2000 Can. J. Vet. Res. pmid:11041498
Trotter GW et al. Effects of intramuscular polysulfated glycosaminoglycan on chemical and physical defects in equine articular cartilage. 1989 Can. J. Vet. Res. pmid:2469533
Chan CB et al. Evidence for defective glucose sensing by islets of fa/fa obese Zucker rats. 1993 Can. J. Physiol. Pharmacol. pmid:8513432
Goodyer AV The abnormal mechanical strength-interval curve of hypoxic rabbit papillary muscle. 1988 Can. J. Physiol. Pharmacol. pmid:3214803
Perks AM et al. Lung liquid production by in vitro lungs from fetal guinea pigs: studies with metabolic inhibitors. 1991 Can. J. Physiol. Pharmacol. pmid:1756423
Rosenthal M and Sick TJ Glycolytic and oxidative metabolic contributions to potassium ion transport in rat cerebral cortex. 1992 Can. J. Physiol. Pharmacol. pmid:1295667
Mainwood GW et al. The effects of metabolic inhibitors on the contraction of creatine-depleted muscle. 1982 Can. J. Physiol. Pharmacol. pmid:7083060
Perks AM et al. Reabsorption of lung liquid produced by 2,4-dinitrophenol in in vitro lungs from fetal guinea pigs. 1993 Can. J. Physiol. Pharmacol. pmid:8390326
Markowitz S et al. Enhancement and inhibition of phagocytic activity in the retinal pigment epithelium. 1981 Can. J. Ophthalmol. pmid:7344763
Goldhar SW et al. Phagocytosis by retinal pigment epithelium: evaluation of modulating agents with an organ culture model. 1984 Can. J. Ophthalmol. pmid:6713267
Schellhorn HE and Hassan HM Response of hydroperoxidase and superoxide dismutase deficient mutants of Escherichia coli K-12 to oxidative stress. 1988 Can. J. Microbiol. pmid:2848619
Bryant RD et al. The role of Thiobacillus albertis glycocalyx in the adhesion of cells to elemental sulfur. 1984 Can. J. Microbiol. pmid:6713305
Hoban DJ and Lyric RM Glutamate uptake in Thiobacillus novellus. 1977 Can. J. Microbiol. pmid:856422
Aspedon A and Nickerson KW The energy dependence of detergent resistance in Enterobacter cloacae: a likely requirement for ATP rather than a proton gradient or a membrane potential. 1994 Can. J. Microbiol. pmid:8012906
Harada T and Mino Y Some properties of p-coumarate decarboxylase from Cladosporium phlei. 1976 Can. J. Microbiol. pmid:10068
Lazure C et al. Primary structure determination of Escherichia coli heat-stable enterotoxin of porcine origin. 1983 Can. J. Biochem. Cell Biol. pmid:6349752
Huber RE and Mathison RD Physical, chemical, and enzymatic studies on the major sucrase of honey bees (Apis mellifera). 1976 Can. J. Biochem. pmid:4203
Callahan JW and Gerrie J GM1-ganglioside and lactosylceramide beta-galactosidase from rabbit brain: inhibitor and substrate competition studies. 1976 Can. J. Biochem. pmid:971464
Carne TJ et al. Studies on phosphoglyceromutase from chicken breast muscle: number and reactivity of sulfhydryl groups. 1976 Can. J. Biochem. pmid:178418
McCall D et al. Effect of ischemia-related metabolic factors on thallium exchange in cultured rat myocardial cells. 1986 May-Jun Can J Cardiol pmid:2424579
Chikuma T et al. Properties of Suc-GPLGP-MCAase and dipeptidyl-aminopeptidase in mouse calvaria-derived osteoblastic cells (MC3T3-E1). 1985 Calcif. Tissue Int. pmid:2988719
Nijweide PJ and van der Plas A Regulation of calcium transport in isolated periosteal cells, effects of hormones and metabolic inhibitors. 1979 Calcif. Tissue Int. pmid:116755
Ramp WK et al. Magnesium and the mineral metabolism of chick embryo tibiae in organ culture. 1977 Calcif Tissue Res pmid:563764
Scarpace PJ and Neuman WF The blood: bone disequilibrium. I. The active accumulation of K+ into the bone extracellular fluid. 1976 Calcif Tissue Res pmid:1260484
Scarpace PJ and Neuman WF The blood: bone disequilibrium. II. Evidence against the active accumulation of calcium or phosphate into the bone extracellular fluid. 1976 Calcif Tissue Res pmid:1260485
Ramp WK et al. Effects of ethanol on chicks in vivo and on chick embryo tibiae in organ culture. 1975 Calcif Tissue Res pmid:1148882
Hicks EP and Ramp WK The effects of fluoride on the mineralization of embryonic chick tibiae in organ culture. 1975 Calcif Tissue Res pmid:1148883
Boiledieu D and Valembois P [Evidence for polypeptide synthesis during cytotoxic reactions in sipunculid worms]. 1978 C. R. Seances Soc. Biol. Fil. pmid:80257
CHASSIN JL and LOCALIO SA The biological chemistry of wound healing; effect of blocking the sulfhydryl group (-SH) in vivo with iodoacetic acid. 1949 Bull N Y Acad Med pmid:18152259
Gupta SR et al. Effect of some inhibitors on aflatoxin-production in a synthetic medium and on the incorporation of acetate-1- 14C into aflatoxins by resting mycelia of Aspergillus parasiticus. 1976 Bull Environ Contam Toxicol pmid:1260151
Roullet B et al. [Determination of serum glycosylated proteins in normoglycemic patients with cancer]. 1987 Bull Cancer pmid:3435788
Unni E et al. Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro. 2005 Breast Cancer Res. pmid:16168115
Jezek P et al. Important amino acid residues of potato plant uncoupling protein (StUCP). 2000 Braz. J. Med. Biol. Res. pmid:11105092
Figueirêdo PM et al. Thiol-independent activity of a cholesterol-binding enterohemolysin produced by enteropathogenic Escherichia coli. 2003 Braz. J. Med. Biol. Res. pmid:14576905
O'Dowd BS et al. Astrocytic glycogenolysis energizes memory processes in neonate chicks. 1994 Brain Res. Dev. Brain Res. pmid:8004768
Rice GE and Barnea A Copper-induced release of immunoreactive alpha-melanotropin from isolated hypothalamic granules. 1983 Brain Res. Bull. pmid:6667383
Martínez AD and Sáez JC Regulation of astrocyte gap junctions by hypoxia-reoxygenation. 2000 Brain Res. Brain Res. Rev. pmid:10751675
Chang TK and Cheng JT Inhibitory effect of xylamine on the uptake of [3H]norepinephrine into primary astrocyte cultures. 1992 Brain Res. pmid:1477731
Andersen BJ and Marmarou A Functional compartmentalization of energy production in neural tissue. 1992 Brain Res. pmid:1511302
Daval JL et al. Release of [14C]adenosine derivatives from superfused synaptosome preparations. Effects of depolarizing agents and metabolic inhibitors. 1980 Brain Res. pmid:7350951
Saito T Glucose-supported oxidative metabolism and evoked potentials are sensitive to fluoroacetate, an inhibitor of glial tricarboxylic acid cycle in the olfactory cortex slice. 1990 Brain Res. pmid:2073603
Maher P et al. A novel approach to screening for new neuroprotective compounds for the treatment of stroke. 2007 Brain Res. pmid:17765210
Reshef A et al. Preconditioning of primary rat neuronal cultures against ischemic injury: characterization of the "time window of protection'. 1996 Brain Res. pmid:9001730