Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Temporomandibular Joint Disorders D013705 4 associated lipids
Arthralgia D018771 8 associated lipids
Osteophyte D054850 2 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Retinitis D012173 4 associated lipids
Theileriasis D013801 7 associated lipids
Muscle Cramp D009120 3 associated lipids
Rigor Mortis D012298 1 associated lipids
Thrombophilia D019851 6 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Lee FS et al. Primary structure of human placental ribonuclease inhibitor. 1988 Biochemistry pmid:3219362
Nieminen AL et al. Calcium dependence of bleb formation and cell death in hepatocytes. 1988 Cell Calcium pmid:3224370
Feeback DL et al. Metabolic myopathy produced by dinitrofluorobenzene inhibition of creatine phosphokinase. 1988 J. Neurol. Sci. pmid:3225621
Chhatwal GS and Gaitonde BB Purification of a nontoxic phospholipase A2 from the venom of Indian krait (Bungarus caeruleus). 1978 Jpn. J. Med. Sci. Biol. pmid:32414
Altland K et al. Isoelectric focusing of basic proteins: the problem of oxidation of cysteines. 1988 Electrophoresis pmid:3243245
Skul'skiÄ­ IA and Pivovarova NB [Effect of inhibitors of energy metabolism on potassium accumulation in the neurons of the mollusk Planorbarius corneus]. 1988 Nov-Dec Zh. Evol. Biokhim. Fiziol. pmid:3245356
Kempski O et al. Molecular mechanisms of glial swelling in vitro. 1988 Jul-Dec Neurochem Pathol pmid:3247066
Thomas JA and Park EM Oxy radical-initiated protein S-thiolation and enzymic dethiolation. 1988 Basic Life Sci. pmid:3250494
Bountra C et al. Mechanism of rate-dependent pH changes in the sheep cardiac Purkinje fibre. 1988 J. Physiol. (Lond.) pmid:3254421
Zoref-Shani E et al. Pathways of adenine nucleotide catabolism in primary rat cardiomyocyte cultures. 1988 J. Mol. Cell. Cardiol. pmid:3259263
Sterchi EE et al. N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase: a metalloendopeptidase of the human intestinal microvillus membrane which degrades biologically active peptides. 1988 Arch. Biochem. Biophys. pmid:3261961
Turkelson CM Effects of ATP synthesis inhibitors, temperature, 8-bromo c-AMP, and calcium omission on release of corticotropin releasing factor from superfused rat hypothalami. 1988 Life Sci. pmid:3262804
Okorokov LA et al. Energy-dependent transport of manganese into yeast cells and distribution of accumulated ions. 1977 Eur. J. Biochem. pmid:328273
Mittenbühler K and Holzer H Purification and characterization of acid trehalase from the yeast suc2 mutant. 1988 J. Biol. Chem. pmid:3286651
Miller DM and Harun SH The kinetics of the active and de-energized transport of O-methyl glucose in Ustilago maydis. 1978 Biochim. Biophys. Acta pmid:32904
Wakabayashi S et al. [Perifusion of monolayer-cultured B cells of the infant rat: a comparative study of the effects of 2-deoxy-2-fluoroglucose and iodoacetic acid]. 1988 Nihon Naibunpi Gakkai Zasshi pmid:3294052
Lockwood BC et al. The use of a highly sensitive electrophoretic method to compare the proteinases of trichomonads. 1987 Mol. Biochem. Parasitol. pmid:3302703
Stokes JB et al. Purification of rat papillary collecting duct cells: functional and metabolic assessment. 1987 Am. J. Physiol. pmid:3303974
Yamamoto K et al. Affinity purification and properties of cathepsin-E-like acid proteinase from rat spleen. 1978 Eur. J. Biochem. pmid:33048
Dunbar JC and Bradshaw RA Amino acid sequence of guinea pig prostate kallikrein. 1987 Biochemistry pmid:3307909
Polgár L and Csoma C Dissociation of ionizing groups in the binding cleft inversely controls the endo- and exopeptidase activities of cathepsin B. 1987 J. Biol. Chem. pmid:3312190
Wakabayashi S et al. Maintenance of neonatal rat B cells in glucose-depleted medium: a perifusion study. 1987 J. Endocrinol. pmid:3312465
Campbell-Burk SL et al. 31P NMR saturation-transfer measurements in Saccharomyces cerevisiae: characterization of phosphate exchange reactions by iodoacetate and antimycin A inhibition. 1987 Biochemistry pmid:3322400
Kagawa S et al. Maintenance of pancreatic endocrine cells of the neonatal rat: Part XII--Development of the response by infant rat pancreatic monolayer-cultured B cells. 1987 Indian J. Biochem. Biophys. pmid:3329630
Andrews PA et al. cis-Diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells. 1988 Cancer Res. pmid:3335000
Zaager S and Burke M Subunit interactions of skeletal muscle myosin and myosin subfragment 1. Evidence for heavy chain-alkali light chain association-dissociation equilibrium. 1988 J. Biol. Chem. pmid:3335556
Maublant JC et al. Hexakis (2-methoxy isobutylisonitrile) technetium-99m and thallium-201 chloride: uptake and release in cultured myocardial cells. 1988 J. Nucl. Med. pmid:3335927
Okitani A et al. Purification and some properties of cathepsin B from rabbit skeletal muscle. 1988 Eur. J. Biochem. pmid:3338470
Shryock JC et al. Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. 1988 Am. J. Physiol. pmid:3344813
Corbo RM et al. Effect of some thiol reagents on erythrocyte adenosine deaminase (ADA) activity. 1988 Enzyme pmid:3345734
Selvaggio AM et al. Mechanisms of H+ secretion by inner medullary collecting duct cells. 1988 Am. J. Physiol. pmid:3348416
Seymour CB and Mothersill C The effect of glycolysis inhibitors on the radiation response of CHO-K1 cells. 1988 Radiat Environ Biophys pmid:3353494
Hirose M et al. Analyses of intramolecular disulfide bonds in proteins by polyacrylamide gel electrophoresis following two-step alkylation. 1988 Anal. Biochem. pmid:3364712
Plank DW and Howard JB Identification of the reactive sulfhydryl and sequences of cysteinyl-tryptic peptides from beef heart aconitase. 1988 J. Biol. Chem. pmid:3372519
Schurr A et al. Lactate-supported synaptic function in the rat hippocampal slice preparation. 1988 Science pmid:3375817
Maiorino M et al. Kinetic mechanism and substrate specificity of glutathione peroxidase activity of ebselen (PZ51). 1988 Biochem. Pharmacol. pmid:3377822
Neeff J and Mecke D In vivo and in vitro studies on the glucose dependent inactivation of yeast cytoplasmic malate dehydrogenase. 1977 Arch. Microbiol. pmid:337921
Chersi A et al. 14C-labeling of synthetic peptides. 1988 J. Immunol. Methods pmid:3379315
Horn V et al. [Experimental arthrosis caused by chemical cartilage damage]. 1988 Jan-Feb Z Orthop Ihre Grenzgeb pmid:3381573
Bouvet OM and Grimont PA Extracellular oxidation of D-glucose by some members of the Enterobacteriaceae. 1988 Jan-Feb Ann. Inst. Pasteur Microbiol. pmid:3382545
Kaya T et al. Purification and properties of alpha-mannosidase from bakers' yeast. 1977 J. Biochem. pmid:338603
Rainard P Adherence, spreading, and locomotion of bovine polymorphs: effect of proteins and metabolic inhibitors. 1988 Vet. Immunol. Immunopathol. pmid:3388760
Bersinger NA et al. Effect of protein synthesis inhibitors and metabolic blockers on the production of placental proteins by the in vitro perfused human placenta. 1988 Gynecol. Obstet. Invest. pmid:3391424
Fishbein WN et al. Clinical assay of the human erythrocyte lactate transporter. I. Principles, procedure, and validation. 1988 Biochem. Med. Metab. Biol. pmid:3395513
Carlsson L A crucial role of ongoing anaerobic glycolysis in attenuating acute ischemia-induced release of myocardial noradrenaline. 1988 J. Mol. Cell. Cardiol. pmid:3398056
Ganote CE and Vander Heide RS Irreversible injury of isolated adult rat myocytes. Osmotic fragility during metabolic inhibition. 1988 Am. J. Pathol. pmid:3400772
Thomas AM et al. The uptake of choline by Streptococcus pneumoniae. 1978 J. Gen. Microbiol. pmid:34010
Bolin R et al. Glycolysis is not required for fluid homeostasis in isolated rabbit lungs. 1988 J. Appl. Physiol. pmid:3403435
Decottignies P et al. Primary structure of the light-dependent regulatory site of corn NADP-malate dehydrogenase. 1988 J. Biol. Chem. pmid:3403553
Mielicki W and Wierzbicki R Factor X-activating activity from Guerin epithelioma. 1988 Neoplasma pmid:3405336
Buttner B et al. Chromate effects on human erythrocytes--investigations on sulphydryl groups, cross-linking of membrane proteins and electromechanical properties in the coulter-counter. 1988 Sci. Total Environ. pmid:3406723
Yamada T and Sugi H 31P NMR study of the regulation of glycogenolysis in iodoacetate-treated skeletal muscle. 1988 Adv. Exp. Med. Biol. pmid:3407526
Kihlström E and Nilsson L Endocytosis of Salmonella typhimurium 395 MS and MR10 by HeLa cells. 1977 Acta Pathol Microbiol Scand B pmid:341644
Gores GJ et al. Extracellular acidosis delays onset of cell death in ATP-depleted hepatocytes. 1988 Am. J. Physiol. pmid:3421314
Hansen SP and Gesser H Extracellular Ca2+, force, and energy state in cardiac tissue of rainbow trout. 1987 Am. J. Physiol. pmid:3425763
Chen CC et al. Rat intestinal trehalase. Studies of the active site. 1987 Biochem. J. pmid:3426558
Seymour CB and Mothersill C The effect of glycolysis inhibitors on the recovery of CHO-K1 cells from split-dose irradiation. 1987 Acta Oncol pmid:3426849
Kingsley-Hickman PB et al. 31P NMR studies of ATP synthesis and hydrolysis kinetics in the intact myocardium. 1987 Biochemistry pmid:3427090
Knipping G et al. Action of lecithin-cholesterol acyltransferase on low-density lipoproteins in native pig plasma. 1987 Biochemistry pmid:3427116
Roullet B et al. [Determination of serum glycosylated proteins in normoglycemic patients with cancer]. 1987 Bull Cancer pmid:3435788
Kobayashi H et al. Effects of arsenic on cholinergic parameters in brain in vitro. 1987 Neuropharmacology pmid:3437937
Pantin VI et al. [Similarity of adhesion to phagocytosis: macrophage interaction with different substrates]. 1987 Tsitologiia pmid:3438934
Zimmerle CT et al. Ligand-induced asymmetry between active sites of cytoplasmic malate dehydrogenase: a chemical modification study. 1987 Biochemistry pmid:3442674
Fontan E and Truffa-Bachi P The threonine-sensitive homoserine dehydrogenase and aspartokinase activities of Escherichia coli K12. Carboxymethylation of the enzyme: threonine binding and inhibition are functionally dissociable. 1978 J. Biol. Chem. pmid:344322
Uruno T et al. Determination of Ca2+-release from the isolated smooth muscle cells in suspension from the guinea-pig ileum. 1987 Nihon Heikatsukin Gakkai Zasshi pmid:3444154
Piper B et al. The influence of various substances on the gliding motility of Mycoplasma mobile 163K. 1987 J. Gen. Microbiol. pmid:3446749
Berni R et al. New crystalline derivatives of bovine liver rhodanese. 1986 Biochem. Int. pmid:3460592
Kajiya H et al. [Effects of three different metabolic inhibitors (2,4-dinitrophenol, iodoacetic acid, 2,4-fluorodinitrobenzene) on the contractility of the geniohyoid and sartorius muscles]. 1986 Fukuoka Shika Daigaku Gakkai Zasshi pmid:3464458
Shapiro R et al. Isolation and characterization of a human colon carcinoma-secreted enzyme with pancreatic ribonuclease-like activity. 1986 Biochemistry pmid:3467790
Cannella C et al. Active site modifications quench intrinsic fluorescence of rhodanese by different mechanisms. 1986 Biochemistry pmid:3467793
Bagnall WE et al. The gastrointestinal absorption of paracetamol in the rat. 1979 J. Pharm. Pharmacol. pmid:34689
Bawden JW et al. Diffusion of fluoride through the rat enamel organ in vitro. 1987 J. Dent. Res. pmid:3476606
Kobayashi T et al. Effect of iodoacetic acid upon cochlear potentials. 1987 Acta Otolaryngol Suppl pmid:3478950
Olesen SP Rapid increase in blood-brain barrier permeability during severe hypoxia and metabolic inhibition. 1986 Brain Res. pmid:3485464
Gilbert SH and Ford LE The thermoelastic effect in rigor muscle of the frog. 1986 J. Muscle Res. Cell. Motil. pmid:3485655
Savel'ev VB [Study of the mechanics and small-angle equatorial x-ray pattern of the frog skeletal muscle during transition and rigor at different temperatures]. 1986 Nov-Dec Biofizika pmid:3492220
Heller KB et al. Peroxidative membrane damage in human erythrocytes induced by a concerted action of iodoacetate, vanadate and ferricyanide. 1987 Biochim. Biophys. Acta pmid:3496117
Abrahamson M et al. Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin. 1987 J. Biol. Chem. pmid:3496337
Hurwitz A Drug uptake into everted intestinal sacs. II. Inhibition of secretion by hypertonicity. 1979 Am. J. Physiol. pmid:35006
Ramp WK et al. Effects of vitamin D deprivation and 1,25-dihydroxyvitamin D3 treatment on ion release from rat tibiae in vitro. 1986 Bone Miner pmid:3508714
Gal S and Gottesman MM The major excreted protein of transformed fibroblasts is an activable acid-protease. 1986 J. Biol. Chem. pmid:3511049
Im JH et al. Energy dependent insulin binding, internalization and degradation in isolated cardiac myocytes from normal and diabetic rats. 1986 J. Mol. Cell. Cardiol. pmid:3514924
Milton DK and Chawla RK Cotton dust contains proteolytic and elastolytic enzymes not inhibited by alpha-1-proteinase inhibitor. 1986 Am. J. Ind. Med. pmid:3515917
Busturia A and Lagunas R Catabolite inactivation of the glucose transport system in Saccharomyces cerevisiae. 1986 J. Gen. Microbiol. pmid:3519857
Ishiura S et al. Ingensin, a fatty acid-activated serine proteinase from rat liver cytosol. 1986 Biochim. Biophys. Acta pmid:3524690
DiMattio J and Streitman J Facilitated glucose transport across the retinal pigment epithelium of the bullfrog (Rana catesbeiana). 1986 Exp. Eye Res. pmid:3525201
Turkiewicz M et al. Purification and characterization of a proteinase from Euphausia superba Dana (Antarctic krill). 1986 Acta Biochim. Pol. pmid:3532651
Plishker GA et al. Involvement of a cytoplasmic protein in calcium-dependent potassium efflux in red blood cells. 1986 Am. J. Physiol. pmid:3532815
Hynes WL and Tagg JR Proteinase-related broad-spectrum inhibitory activity among group-A streptococci. 1986 J. Med. Microbiol. pmid:3534275
Helm BA and Gunn JM The effect of insulinomimetic agents on protein degradation in H35 hepatoma cells. 1986 Mol. Cell. Biochem. pmid:3534545
Pacchiarini L et al. Role of tumor proteinases in tumor cell-induced platelet aggregation. 1986 Invasion Metastasis pmid:3536793
Reizer J and Saier MH Mechanism and regulation of phosphate transport in Streptococcus pyogenes. 1987 J. Bacteriol. pmid:3539921
Wakabayashi S et al. [The effect of glucose concentrations on the functional maturation of monolayer-cultured B cells of neonatal rat pancreases]. 1986 Nihon Naibunpi Gakkai Zasshi pmid:3542593
Shieh JH et al. Purification and characterization of human colony-stimulating factor 1 from human pancreatic carcinoma (MIA PaCa-2) cells. 1987 Arch. Biochem. Biophys. pmid:3545083
Takeda M et al. Isolation, and catalytic and immunochemical properties of cathepsin D-like acid proteinase from rat erythrocytes. 1986 J. Biochem. pmid:3546279
Wada A Analysis of Escherichia coli ribosomal proteins by an improved two dimensional gel electrophoresis. II. Characterization of four new proteins. 1986 J. Biochem. pmid:3553169
Yasuhara T and Ohashi A New chelator-sensitive proteases in matrix of yeast mitochondria. 1987 Biochem. Biophys. Res. Commun. pmid:3555485
Aurich H et al. [Kinetics of membrane-bound aldehyde dehydrogenase from Acinetobacter calcoaceticus]. 1987 Biol. Chem. Hoppe-Seyler pmid:3566912
Hermsdorf CL Tripeptide-specific aminopeptidase from Escherichia coli AJ005. 1978 Biochemistry pmid:356879
Jarroll EL et al. Giardia lamblia: uptake of pyrimidine nucleosides. 1987 Exp. Parasitol. pmid:3569473