| MeSH term | MeSH ID | Detail |
|---|---|---|
| Temporomandibular Joint Disorders | D013705 | 4 associated lipids |
| Arthralgia | D018771 | 8 associated lipids |
| Osteophyte | D054850 | 2 associated lipids |
| Glycogen Storage Disease | D006008 | 4 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Retinitis | D012173 | 4 associated lipids |
| Theileriasis | D013801 | 7 associated lipids |
| Muscle Cramp | D009120 | 3 associated lipids |
| Rigor Mortis | D012298 | 1 associated lipids |
| Thrombophilia | D019851 | 6 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| de Boer J et al. | Continuous monitoring of extracellular lactate concentration by microdialysis lactography for the study of rat muscle metabolism in vivo. | 1991 | Pflugers Arch. | pmid:1945755 |
| Ballanyi K et al. | Functional relevance of anaerobic metabolism in the isolated respiratory network of newborn rats. | 1996 | Pflugers Arch. | pmid:8764977 |
| di Prampero PE et al. | Efficiency of work performance and contraction velocity in isotonic tetani of frog sartorius. | 1988 | Pflugers Arch. | pmid:3194167 |
| John SA et al. | Dynamic modulation of intracellular glucose imaged in single cells using a FRET-based glucose nanosensor. | 2008 | Pflugers Arch. | pmid:18071748 |
| Kito Y and Suzuki H | Effects of temperature on pacemaker potentials in the mouse small intestine. | 2007 | Pflugers Arch. | pmid:17235578 |
| Silberberg SD and van Breemen C | A potassium current activated by lemakalim and metabolic inhibition in rabbit mesenteric artery. | 1992 | Pflugers Arch. | pmid:1553259 |
| Bullock AJ and Wray S | The effects of metabolic inhibition on force, Ca2+ and pHi in guinea-pig ureteric smooth muscle. | 1998 | Pflugers Arch. | pmid:9382937 |
| Stulc J et al. | Uptake of inorganic phosphate by the maternal border of the guinea pig placenta. | 1982 | Pflugers Arch. | pmid:7155806 |
| Bozem M et al. | Inosine partially mimics the effects of glucose on ionic fluxes, electrical activity, and insulin release in mouse pancreatic B-cells. | 1987 | Pflugers Arch. | pmid:2448739 |
| Said HM et al. | Studies on the intestinal surface acid microclimate: developmental aspects. | 1987 | Pediatr. Res. | pmid:3684377 |
| Nevalainen TJ et al. | The effect of rigor mortis on the passage of erythrocytes and fluid through the myocardium of isolated dog hearts. | 1978 | Pathology | pmid:724286 |
| Coombs GH | Proteinases of Leishmania mexicana and other flagellate protozoa. | 1982 | Parasitology | pmid:6460959 |
| Li S et al. | Long-term storage of Clonorchis sinensis metacercariae in vitro. | 2006 | Parasitol. Res. | pmid:16767424 |
| La Porta C et al. | Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate. | 2013 | Pain | pmid:23199705 |
| Schuelert N et al. | Local application of the endocannabinoid hydrolysis inhibitor URB597 reduces nociception in spontaneous and chemically induced models of osteoarthritis. | 2011 | Pain | pmid:21185649 |
| Okun A et al. | Afferent drive elicits ongoing pain in a model of advanced osteoarthritis. | 2012 | Pain | pmid:22387095 |
| Ivanavicius SP et al. | Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF-3 and pharmacological characterisation. | 2007 | Pain | pmid:17276007 |
| Zhou X et al. | Protective Effect of Edaravone in Primary Cerebellar Granule Neurons against Iodoacetic Acid-Induced Cell Injury. | 2015 | Oxid Med Cell Longev | pmid:26557222 |
| Swearingen CA et al. | A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs. | 2010 | Osteoarthr. Cartil. | pmid:20633676 |
| Strassle BW et al. | Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease. | 2010 | Osteoarthr. Cartil. | pmid:20633675 |
| Thote T et al. | Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration. | 2013 | Osteoarthr. Cartil. | pmid:23747340 |
| Kelly S et al. | Spinal nociceptive reflexes are sensitized in the monosodium iodoacetate model of osteoarthritis pain in the rat. | 2013 | Osteoarthr. Cartil. | pmid:23973147 |
| Mapp PI et al. | Differences in structural and pain phenotypes in the sodium monoiodoacetate and meniscal transection models of osteoarthritis. | 2013 | Osteoarthr. Cartil. | pmid:23973148 |
| Cifuentes DJ et al. | Decrease in oxidative stress and histological changes induced by physical exercise calibrated in rats with osteoarthritis induced by monosodium iodoacetate. | 2010 | Osteoarthr. Cartil. | pmid:20417294 |
| Clements KM et al. | Cellular and histopathological changes in the infrapatellar fat pad in the monoiodoacetate model of osteoarthritis pain. | 2009 | Osteoarthr. Cartil. | pmid:19114312 |
| Piscaer TM et al. | In vivo imaging of cartilage degeneration using microCT-arthrography. | 2008 | Osteoarthr. Cartil. | pmid:18342549 |
| Barve RA et al. | Transcriptional profiling and pathway analysis of monosodium iodoacetate-induced experimental osteoarthritis in rats: relevance to human disease. | 2007 | Osteoarthr. Cartil. | pmid:17500014 |
| Schuelert N and McDougall JJ | Electrophysiological evidence that the vasoactive intestinal peptide receptor antagonist VIP6-28 reduces nociception in an animal model of osteoarthritis. | 2006 | Osteoarthr. Cartil. | pmid:16740398 |
| Oestergaard S et al. | The utility of measuring C-terminal telopeptides of collagen type II (CTX-II) in serum and synovial fluid samples for estimation of articular cartilage status in experimental models of destructive joint diseases. | 2006 | Osteoarthr. Cartil. | pmid:16500121 |
| Janusz MJ et al. | Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration. | 2004 | Osteoarthr. Cartil. | pmid:15325638 |
| Bove SE et al. | Weight bearing as a measure of disease progression and efficacy of anti-inflammatory compounds in a model of monosodium iodoacetate-induced osteoarthritis. | 2003 | Osteoarthr. Cartil. | pmid:14609535 |
| Moon SJ et al. | Rebamipide attenuates pain severity and cartilage degeneration in a rat model of osteoarthritis by downregulating oxidative damage and catabolic activity in chondrocytes. | 2012 | Osteoarthr. Cartil. | pmid:22890185 |
| Janusz MJ et al. | Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors. | 2001 | Osteoarthr. Cartil. | pmid:11795995 |
| Kelly S et al. | Spontaneous firing in C-fibers and increased mechanical sensitivity in A-fibers of knee joint-associated mechanoreceptive primary afferent neurones during MIA-induced osteoarthritis in the rat. | 2012 | Osteoarthr. Cartil. | pmid:22285737 |
| Dumond H et al. | Site specific changes in gene expression and cartilage metabolism during early experimental osteoarthritis. | 2004 | Osteoarthr. Cartil. | pmid:15023380 |
| Moilanen LJ et al. | Monosodium iodoacetate-induced inflammation and joint pain are reduced in TRPA1 deficient mice--potential role of TRPA1 in osteoarthritis. | 2015 | Osteoarthr. Cartil. | pmid:26521748 |
| McDougall JJ et al. | Lysophosphatidic acid provides a missing link between osteoarthritis and joint neuropathic pain. | 2017 | Osteoarthr. Cartil. | pmid:27651153 |
| Thirunavukkarasu K et al. | Identification and pharmacological characterization of a novel inhibitor of autotaxin in rodent models of joint pain. | 2017 | Osteoarthr. Cartil. | pmid:27638130 |
| Sagar DR et al. | Dissecting the contribution of knee joint NGF to spinal nociceptive sensitization in a model of OA pain in the rat. | 2015 | Osteoarthr. Cartil. | pmid:25623624 |
| Boudenot A et al. | Effect of interval-training exercise on subchondral bone in a chemically-induced osteoarthritis model. | 2014 | Osteoarthr. Cartil. | pmid:24928318 |
| Schuelert N et al. | Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain. | 2010 | Osteoarthr. Cartil. | pmid:20863899 |
| Ono M et al. | Purification and characterization of a thiol-protease from Bacteroides gingivalis strain 381. | 1987 | Oral Microbiol. Immunol. | pmid:10870472 |
| Ponte F et al. | Iodoacetic acid influence on the aerobic glycolysis in surviving retinae of normal rats and of carriers of inherited retinal degeneration. | 1974 | Ophthalmologica | pmid:4852565 |
| Ono S and Hirano H | Riboflavin metabolism in the single lens of rat. | 1983 | Ophthalmic Res. | pmid:6634050 |
| Delamere NA and Paterson CA | Studies on calcium regulation in relation to sodium-potassium balance in the rabbit lens. | 1982 | Ophthalmic Res. | pmid:7099540 |
| Shen Y et al. | Effect of Guanabenz on Rat AMD Models and Rabbit Choroidal Blood Flow. | 2011 | Open Ophthalmol J | pmid:21633720 |
| Sarigianni M et al. | Involvement of signaling molecules on na/h exchanger-1 activity in human monocytes. | 2010 | Open Cardiovasc Med J | pmid:21160910 |
| Knock FE et al. | Effects of selected sulfhydryl inhibitors on nonhistone chromosomal proteins of HeLa cells. | 1975 | Oncology | pmid:1228540 |
| Reyes-FermÃn LM et al. | Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death. | 2012 | Nutr Neurosci | pmid:22776704 |
| Gallis JL et al. | A metabolic link between mitochondrial ATP synthesis and liver glycogen metabolism: NMR study in rats re-fed with butyrate and/or glucose. | 2011 | Nutr Metab (Lond) | pmid:21676253 |