Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

Cross Reference

Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Temporomandibular Joint Disorders D013705 4 associated lipids
Arthralgia D018771 8 associated lipids
Osteophyte D054850 2 associated lipids
Glycogen Storage Disease D006008 4 associated lipids
Hypertrophy, Left Ventricular D017379 12 associated lipids
Retinitis D012173 4 associated lipids
Theileriasis D013801 7 associated lipids
Muscle Cramp D009120 3 associated lipids
Rigor Mortis D012298 1 associated lipids
Thrombophilia D019851 6 associated lipids
Per page 10 20 50 100 | Total 54

PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

Download all related citations
Per page 10 20 50 100 | Total 2490
Authors Title Published Journal PubMed Link
Balhorn R et al. Identification of bull protamine disulfides. 1991 Biochemistry pmid:1988019
Yamada R and Bradshaw RA Rat liver polysome N alpha-acetyltransferase: isolation and characterization. 1991 Biochemistry pmid:1989673
Lawson SL et al. Effects of both shortening and lengthening the active site nucleophile of Bacillus circulans xylanase on catalytic activity. 1996 Biochemistry pmid:8756474
Collinson IR et al. The F1F0-ATPase complex from bovine heart mitochondria: the molar ratio of the subunits in the stalk region linking the F1 and F0 domains. 1996 Biochemistry pmid:8823202
Xiong H et al. Role of cysteine-82 in the catalytic mechanism of human S-adenosylmethionine decarboxylase. 1999 Biochemistry pmid:10029540
Hatcher VB et al. Purification, properties, and partial structure elucidation of a high-molecular-weight glycoprotein from cervical mucus of the bonnet monkey (Macaca radiata). 1977 Biochemistry pmid:402940
Flitsch SL and Khorana HG Structural studies on transmembrane proteins. 1. Model study using bacteriorhodopsin mutants containing single cysteine residues. 1989 Biochemistry pmid:2692704
Kanaani J et al. Identification of the active sites of human and schistosomal hypoxanthine-guanine phosphoribosyltransferases by GMP-2',3'-dialdehyde affinity labeling. 1995 Biochemistry pmid:7578112
Qiao ZS et al. Putative disulfide-forming pathway of porcine insulin precursor during its refolding in vitro. 2001 Biochemistry pmid:11258877
Raia CA et al. Activation of Sulfolobus solfataricus alcohol dehydrogenase by modification of cysteine residue 38 with iodoacetic acid. 1996 Biochemistry pmid:8555238
Turner E et al. Ovothiols, a family of redox-active mercaptohistidine compounds from marine invertebrate eggs. 1987 Biochemistry pmid:3651433
Hermsdorf CL Tripeptide-specific aminopeptidase from Escherichia coli AJ005. 1978 Biochemistry pmid:356879
Sahin-Tóth M and Kaback HR Functional conservation in the putative substrate binding site of the sucrose permease from Escherichia coli. 2000 Biochemistry pmid:10821691
Fujioka M et al. Recombinant rat liver guanidinoacetate methyltransferase: reactivity and function of sulfhydryl groups. 1988 Biochemistry pmid:3207695
Lee FS et al. Primary structure of human placental ribonuclease inhibitor. 1988 Biochemistry pmid:3219362
Waheed A et al. Purification and physicochemical characterization of a human placental acid phosphatase possessing phosphotyrosyl protein phosphatase activity. 1988 Biochemistry pmid:2844226
Schwarz H et al. Stability studies on derivatives of the bovine pancreatic trypsin inhibitor. 1987 Biochemistry pmid:2443162
Kaslow HR and Lesikar DD Sulfhydryl-alkylating reagents inactivate the NAD glycohydrolase activity of pertussis toxin. 1987 Biochemistry pmid:2822091
Evans AC and Wilkinson KD Ubiquitin-dependent proteolysis of native and alkylated bovine serum albumin: effects of protein structure and ATP concentration on selectivity. 1985 Biochemistry pmid:2990536
Weickmann JL et al. Purification and characterization of human pancreatic ribonuclease. 1981 Biochemistry pmid:6784751
Zimmerle CT and Alter GM Crystallization-induced modification of cytoplasmic malate dehydrogenase structure and function. 1983 Biochemistry pmid:6661435
Fernandez-Luna JL et al. Complete amino acid sequence of the Aspergillus cytotoxin mitogillin. 1985 Biochemistry pmid:3994994
Forstrom JW et al. Identification of the catalytic site of rat liver glutathione peroxidase as selenocysteine. 1978 Biochemistry pmid:678534
Thomas ML and Tack BF Identification and alignment of a thiol ester site in the third component of guinea pig complement. 1983 Biochemistry pmid:6838833
Donadio S et al. Alkylation of amide linkages and cleavage of the C chain in the enzyme-activated-substrate inhibition of alpha-chymotrypsin with N-nitrosamides. 1985 Biochemistry pmid:4016069
Ralat LA and Colman RF Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. 2006 Biochemistry pmid:17029404
Rudnick G and Abeles RH Reaction mechanism and structure of the active site of proline racemase. 1975 Biochemistry pmid:1174513
Chicheportiche R et al. Structure-function relationship in the binding of snake neurotoxins to the torpedo membrane receptor. 1975 Biochemistry pmid:1148159
Zhang ZY et al. Covalent modification and active site-directed inactivation of a low molecular weight phosphotyrosyl protein phosphatase. 1992 Biochemistry pmid:1737025
Beyer WF and Fridovich I Pseudocatalase from Lactobacillus plantarum: evidence for a homopentameric structure containing two atoms of manganese per subunit. 1985 Biochemistry pmid:4084532
Ashiba G and Szent-Györgyi AG Essential light chain exchange in scallop myosin. 1985 Biochemistry pmid:4084545
Brindle KM 31P NMR magnetization-transfer measurements of flux between inorganic phosphate and adenosine 5'-triphosphate in yeast cells genetically modified to overproduce phosphoglycerate kinase. 1988 Biochemistry pmid:3056522
Fraij B and Hartman FC Isolation and sequencing of an active-site peptide from Rhodospirillum rubrum ribulosebisphosphate carboxylase/oxygenase after affinity labeling with 2-[(bromoacetyl)amino]pentitol 1,5-bisphosphate. 1983 Biochemistry pmid:6404301
Dayton WR et al. A Ca2+-activated protease possibly involved in myofibrillar protein turnover. Partial characterization of the purified enzyme. 1976 Biochemistry pmid:1276131
Habersetzer-Rochat C and Sampieri F Structure-function relationships of scorpion neurotoxins. 1976 Biochemistry pmid:819030
Nagae S et al. Purification and properties of a neutral endodeoxyribonuclease from rat small intestinal mucosa. 1982 Biochemistry pmid:7074091
Denu JM et al. The catalytic role of aspartic acid-92 in a human dual-specific protein-tyrosine-phosphatase. 1995 Biochemistry pmid:7880835
Zhang ZY et al. Catalytic function of the conserved hydroxyl group in the protein tyrosine phosphatase signature motif. 1995 Biochemistry pmid:8845365
Lange LG et al. The role of arginyl residues in directing carboxymethylation of horse liver alcohol dehydrogenase. 1975 Biochemistry pmid:167828
Byers LD and Koshland DE The specificity of induced conformational changes. The case of yeast glyceraldehyde-3-phosphate dehydrogenase. 1975 Biochemistry pmid:169882
Mende TJ and Moreno M A heat stable paraoxonase (O,O-diethyl O-p-nitrophenyl phosphate O-p-nitrophenyl hydrolase) from Russell's viper venom. 1975 Biochemistry pmid:169891
Reynolds EE et al. Adenosine 5'-triphosphate independent secretion from PC12 pheochromocytoma cells. 1982 Biochemistry pmid:7138829
Franzen JS et al. Half-of-the-sites reactivity of bovine liver uridine diphosphoglucose dehydrogenase toward iodoacetate and iodoacetamide. 1976 Biochemistry pmid:187220
Coulin F et al. Identification of Cys-150 in the active site of phosphomannose isomerase from Candida albicans. 1993 Biochemistry pmid:8260497
Jörnvall H et al. Probe of beta-galactosidase structure with iodoacetate. Differential reactivity of thiol groups in wild-type and mutant forms of beta-galactosidase. 1978 Biochemistry pmid:103570
Jones JG et al. Essential and nonessential thiols of yeast hexokinase. Reactions with iodoacetate and iodoacetamide. 1975 Biochemistry pmid:237532
Chandra A et al. Modification of aldose reductase by S-nitrosoglutathione. 1997 Biochemistry pmid:9398310
Klinman JP The interaction of an epoxide with yeast alcohol dehydrogenase: evidence for binding and the modification of two active site cysteines by styrene oxide. 1975 Biochemistry pmid:238561
Dadlez M and Kim PS Rapid formation of the native 14-38 disulfide bond in the early stages of BPTI folding. 1996 Biochemistry pmid:8973187
Ehrlich RS and Colman RF Coenzyme binding by native and chemically modified pig heart triphosphopyridine nucleotide dependent isocitrate dehydrogenase. 1975 Biochemistry pmid:241396
Larsson LJ et al. Subunits of human alpha 2-macroglobulin produced by specific reduction of interchain disulfide bonds with thioredoxin. 1988 Biochemistry pmid:2452651
Zimmerle CT et al. Ligand-induced asymmetry between active sites of cytoplasmic malate dehydrogenase: a chemical modification study. 1987 Biochemistry pmid:3442674
Zapun A et al. Replacement of the active-site cysteine residues of DsbA, a protein required for disulfide bond formation in vivo. 1994 Biochemistry pmid:8110795
Dixit SN and Kang AH Basement membrane collagens. Cyanogen bromide peptides of the D chain from porcine kidney. 1980 Biochemistry pmid:7397099
Shapiro R et al. Isolation and characterization of a human colon carcinoma-secreted enzyme with pancreatic ribonuclease-like activity. 1986 Biochemistry pmid:3467790
Cannella C et al. Active site modifications quench intrinsic fluorescence of rhodanese by different mechanisms. 1986 Biochemistry pmid:3467793
Zhang ZY and Dixon JE Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402. 1993 Biochemistry pmid:8369304
Ohnoki S et al. Glutamine active site of formylglycinamide ribonucleotide amidotransferase. 1. Labeling of the enzyme with iodoacetate. 1977 Biochemistry pmid:14669
Wu L and Zhang ZY Probing the function of Asp128 in the lower molecular weight protein-tyrosine phosphatase-catalyzed reaction. A pre-steady-state and steady-state kinetic investigation. 1996 Biochemistry pmid:8611532
Quick M and Jung H A conserved aspartate residue, Asp187, is important for Na+-dependent proline binding and transport by the Na+/proline transporter of Escherichia coli. 1998 Biochemistry pmid:9753469
DiPolo R and Caputo C The effect of ATP on calcium efflux in dialyzed barnacle muscle fibres. 1977 Biochim. Biophys. Acta pmid:411508
Graupe K et al. Interaction between catalytic and regulatory sites of the pyruvate dehydrogenase from Escherichia coli studied by the ESR technique. 1989 Biochim. Biophys. Acta pmid:2557092
Labib RS et al. Studies on extracellular proteases of Streptococcus sanguis. Purification and characterization of a human IgA1 specific protease. 1978 Biochim. Biophys. Acta pmid:102357
Wolf MB and Baynes JW The anti-cancer drug, doxorubicin, causes oxidant stress-induced endothelial dysfunction. 2006 Biochim. Biophys. Acta pmid:16337743
Levy R and Livne A Erythrocyte Lii-Nao countertransport system. Inhibition by N-ethylmaleimide probes for a conformational change of the transport system. 1984 Biochim. Biophys. Acta pmid:6487623
Leonard JL and Visser TJ Selective modification of the active center of renal iodothyronine 5'-deiodinase by iodoacetate. 1984 Biochim. Biophys. Acta pmid:6733113
Ott P and Brodbeck U Amphiphile dependency of the monomeric and dimeric forms of acetylcholinesterase from human erythrocyte membrane. 1984 Biochim. Biophys. Acta pmid:6466662
Chashchin VL et al. The domain structure of the cholesterol side-chain cleavage cytochrome P-450 from bovine adrenocortical mitochondria. 1984 Biochim. Biophys. Acta pmid:6722173
Sams CF and Matthews KS Chemical modification of dopamine beta-hydroxylase. 1984 Biochim. Biophys. Acta pmid:6722174
Cooke RD et al. Purification and characterisation of polygalacturonases from a commercial Aspergillus niger preparation. 1976 Biochim. Biophys. Acta pmid:1009121
Myöhänen T and Mäntsälä P Evidence for the importance of cysteine and arginine residues in Pseudomonas fluorescens UK-1 pantoate dehydrogenase. 1980 Biochim. Biophys. Acta pmid:6773579
Zeidan HM et al. Microenvironment around the essential cysteine residues in chicken liver fructose-1,6-bisphosphatase as analyzed by ESR spin labelling. 1986 Biochim. Biophys. Acta pmid:3004586
Chen CH et al. Synthesis and secretion of lecithin-cholesterol acyltransferase by the human hepatoma cell line HepG2. 1986 Biochim. Biophys. Acta pmid:3015221
Ogawa H et al. Amino acid sequence of a peptide containing an essential cysteine residue of yeast saccharopine dehydrogenase (L-lysine-forming). 1980 Biochim. Biophys. Acta pmid:6769500
Martínez-Izquierdo JA et al. Role of the adenylate system and glycolytic flux in the control of protein synthesis in isolated rat lung cells. 1982 Biochim. Biophys. Acta pmid:6291628
Ostenson CG et al. Effects of metabolic inhibitors on the regulation of pancreatic glucagon release. 1980 Biochim. Biophys. Acta pmid:6986917
Bode HP et al. Vanadium uptake by yeast cells. 1990 Biochim. Biophys. Acta pmid:2155019
Ursini F et al. The selenoenzyme phospholipid hydroperoxide glutathione peroxidase. 1985 Biochim. Biophys. Acta pmid:3978121
Pliszka B and Lu RC Reactivities of thiols in myosin rod: effect of magnesium and ionic strength. 1985 Biochim. Biophys. Acta pmid:4027253
Le Gaillard F et al. Reversible dissociation of cortisol-transcortin complex by sodium para-chloromercuribenzoate. 1983 Biochim. Biophys. Acta pmid:6419776
Horowitz P and Criscimagna NL The specificity of active-site alkylation by iodoacetic acid in the enzyme thiosulfate sulfurtransferase. 1982 Biochim. Biophys. Acta pmid:6952939
Morand O et al. Effect of albumin, low temperature and metabolic inhibitors on transport of fatty acids into cultured human leukemic myeloid cells. 1982 Biochim. Biophys. Acta pmid:6960927
Nagase H et al. Identification of plasma kallikrein as an activator of latent collagenase in rheumatoid synovial fluid. 1982 Biochim. Biophys. Acta pmid:6279161
Vezzoli A et al. Quantitative analysis of anaerobic metabolism in resting anoxic muscle by 31P and 1H MRS. 1997 Biochim. Biophys. Acta pmid:9452766
Fuhrmann GF et al. The effect of ferricyanide with iodoacetate in calcium-free solution on passive cation permeability in human red blood cells: comparison with the Gardos-effect and with the influence of PCMBS on passive cation permeability. 1989 Biochim. Biophys. Acta pmid:2547446
Mehrotra S et al. Mutational analysis of cysteine 328 and cysteine 368 at the interface of Plasmodium falciparum adenylosuccinate synthetase. 2012 Biochim. Biophys. Acta pmid:22289630
Pensa B et al. Selective reactivity of rhodanese sulfhydryl groups with 5,5'-dithio-bis(2-nitrobenzoic acid). 1977 Biochim. Biophys. Acta pmid:911854
Miles PR et al. The effect of inorganic phosphate on sodium fluxes in dog red blood cells. 1977 Biochim. Biophys. Acta pmid:921968
Ivanics T et al. Intracellular sodium in cardiomyocytes using 23Na nuclear magnetic resonance. 1994 Biochim. Biophys. Acta pmid:8148390
Bhatnagar A et al. Human placental aldose reductase: role of Cys-298 in substrate and inhibitor binding. 1994 Biochim. Biophys. Acta pmid:8155699
Ghosh AK et al. Purification and properties of xylan hydrolase from mushroom Termitomyces clypeatus. 1980 Biochim. Biophys. Acta pmid:7189122
Pecci L et al. Cyanylation of rhodanese by 2-nitro-5-thiocyanobenzoic acid. 1980 Biochim. Biophys. Acta pmid:6930978
Heinonen E and Akerman KE Intracellular free magnesium in synaptosomes measured with entrapped eriochrome blue. 1987 Biochim. Biophys. Acta pmid:2436663
Smith RE and MacQuarrie R The role of cysteine residues in the catalytic activity of glycerol-3-phosphate dehydrogenase. 1979 Biochim. Biophys. Acta pmid:36150
Brockbank WJ and Lynn KR Purification and preliminary characterization of two asclepains from the latex of Asclepias syriaca L. (milkweed). 1979 Biochim. Biophys. Acta pmid:36921
Duncan R and Lloyd JB Pinocytosis in the rat visceral yolk sac. Effects of temperature, metabolic inhibitors and some other modifiers. 1978 Biochim. Biophys. Acta pmid:103581
Skrede S et al. The effects of alkylthioacetic acids (3-thia fatty acids) on fatty acid metabolism in isolated hepatocytes. 1989 Biochim. Biophys. Acta pmid:2804058
Yamamoto S and Kawasaki T The involvement of the membrane oxidoreduction system in stimulating amino acid uptake in Ehrlich ascites tumor cells. 1981 Biochim. Biophys. Acta pmid:7260073
Kozka IJ and Gould MK Multiple effects of sulphydryl reagents on sugar transport by rat soleus muscle. 1982 Biochim. Biophys. Acta pmid:6288096
Franzen JS et al. Induced versus pre-existing asymmetry models for the half-of-the-sites reactivity effect in bovine liver uridine diphosphoglucose dehydrogenase. 1980 Biochim. Biophys. Acta pmid:7407191