| MeSH term | MeSH ID | Detail |
|---|---|---|
| Temporomandibular Joint Disorders | D013705 | 4 associated lipids |
| Arthralgia | D018771 | 8 associated lipids |
| Osteophyte | D054850 | 2 associated lipids |
| Glycogen Storage Disease | D006008 | 4 associated lipids |
| Hypertrophy, Left Ventricular | D017379 | 12 associated lipids |
| Retinitis | D012173 | 4 associated lipids |
| Theileriasis | D013801 | 7 associated lipids |
| Muscle Cramp | D009120 | 3 associated lipids |
| Rigor Mortis | D012298 | 1 associated lipids |
| Thrombophilia | D019851 | 6 associated lipids |
Iodoacetic acid
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
Cross Reference
Introduction
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Iodoacetic acid?
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
PubChem Associated disorders and diseases
What pathways are associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Iodoacetic acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with Iodoacetic acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
What genes are associated with Iodoacetic acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Iodoacetic acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Iodoacetic acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Schmidt MM and Dringen R | Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes. | 2009 | Front Neuroenergetics | pmid:19584905 |
| Chaplain RA | Intracellular recordings from granule cells in the rabbit bulbus olfactorius. | 1976 | Neurosci. Lett. | pmid:19604875 |
| Burow LC et al. | Anaerobic central metabolic pathways active during polyhydroxyalkanoate production in uncultured cluster 1 Defluviicoccus enriched in activated sludge communities. | 2009 | FEMS Microbiol. Lett. | pmid:19622073 |
| Santos SB et al. | The use of antibiotics to improve phage detection and enumeration by the double-layer agar technique. | 2009 | BMC Microbiol. | pmid:19627589 |
| pmid:19655297 | ||||
| Rahman W et al. | Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain. | 2009 | Mol Pain | pmid:19664204 |
| pmid:19669390 | ||||
| Ahamed J et al. | In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1. | 2009 | PLoS ONE | pmid:19672301 |
| Burow LC et al. | Induction of membrane permeability in Escherichia coli mediated by lysis protein of the ColE7 operon. | 2009 | FEMS Microbiol. Lett. | pmid:19673051 |
| Volate S et al. | TJ-41 Induces Apoptosis and Potentiates the Apoptotic Effects of 5-FU in Breast Cancer Cell Lines. | 2009 | J Oncol | pmid:19710936 |
| Jones DP and Liang Y | Measuring the poise of thiol/disulfide couples in vivo. | 2009 | Free Radic. Biol. Med. | pmid:19715755 |
| pmid:19716399 | ||||
| Xiang T et al. | Localization and quantitation of free sulfhydryl in recombinant monoclonal antibodies by differential labeling with 12C and 13C iodoacetic acid and LC-MS analysis. | 2009 | Anal. Chem. | pmid:19722496 |
| Brumshtein B et al. | Characterization of gene-activated human acid-beta-glucosidase: crystal structure, glycan composition, and internalization into macrophages. | 2010 | Glycobiology | pmid:19741058 |
| Cialdai C et al. | Effect of Intra-articular 4-(S)-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl} piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a kinin B2 receptor antagonist, on nociceptive response in monosodium iodoacetate-induced experimental osteoarthritis in rats. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19745108 |
| Charles RC et al. | Comparative proteomic analysis of the PhoP regulon in Salmonella enterica serovar Typhi versus Typhimurium. | 2009 | PLoS ONE | pmid:19746165 |
| Lur G et al. | Ribosome-free terminals of rough ER allow formation of STIM1 puncta and segregation of STIM1 from IP(3) receptors. | 2009 | Curr. Biol. | pmid:19765991 |
| Castillo-Romero A et al. | Participation of actin on Giardia lamblia growth and encystation. | 2009 | PLoS ONE | pmid:19774081 |
| Tolonen AC et al. | Targeted gene inactivation in Clostridium phytofermentans shows that cellulose degradation requires the family 9 hydrolase Cphy3367. | 2009 | Mol. Microbiol. | pmid:19775243 |
| pmid:19784812 | ||||
| Bar-Yehuda S et al. | Induction of an antiinflammatory effect and prevention of cartilage damage in rat knee osteoarthritis by CF101 treatment. | 2009 | Arthritis Rheum. | pmid:19790055 |
| Eeckhout Y and Vaes G | Further studies on the activation of procollagenase, the latent precursor of bone collagenase. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation. | 1977 | Biochem. J. | pmid:197917 |
| Galli GL et al. | Ca2+ cycling in cardiomyocytes from a high-performance reptile, the varanid lizard (Varanus exanthematicus). | 2009 | Am. J. Physiol. Regul. Integr. Comp. Physiol. | pmid:19812356 |
| Nasu T et al. | Iodoacetic acid-induced rigor in ileal longitudinal smooth muscle of guinea-pig. | 1990 | Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol. | pmid:1982870 |
| pmid:19853890 | ||||
| Van Tol A et al. | Net mass transfer of cholesteryl esters from low density lipoproteins to high density lipoproteins in plasma from normolipidemic subjects. | 1991 Jan-Feb | Arterioscler. Thromb. | pmid:1988004 |
| Balhorn R et al. | Identification of bull protamine disulfides. | 1991 | Biochemistry | pmid:1988019 |
| Lee SJ et al. | Alterations in membrane transport function and cell viability induced by ATP depletion in primary cultured rabbit renal proximal tubular cells. | 2009 | Korean J. Physiol. Pharmacol. | pmid:19885021 |
| Knap AK and Pratt RF | Inactivation of the RTEM-1 cysteine beta-lactamase by iodoacetate. The nature of active-site functional groups and comparisons with the native enzyme. | 1991 | Biochem. J. | pmid:1989590 |
| Yamada R and Bradshaw RA | Rat liver polysome N alpha-acetyltransferase: isolation and characterization. | 1991 | Biochemistry | pmid:1989673 |
| Samra ZQ et al. | Synthesis of cholesterol-conjugated magnetic nanoparticles for purification of human paraoxonase 1. | 2010 | Appl. Biochem. Biotechnol. | pmid:19902382 |
| Harvey VL et al. | A Selective Role for alpha3 Subunit Glycine Receptors in Inflammatory Pain. | 2009 | Front Mol Neurosci | pmid:19915732 |
| Jinka R et al. | Purification and characterization of cysteine protease from germinating cotyledons of horse gram. | 2009 | BMC Biochem. | pmid:19919695 |
| Wilson CG et al. | Aggrecanolysis and in vitro matrix degradation in the immature bovine meniscus: mechanisms and functional implications. | 2009 | Arthritis Res. Ther. | pmid:19919704 |
| Yang D et al. | Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L). | 2010 | Cancer Biol. Ther. | pmid:19923925 |
| pmid:19924981 | ||||
| Wartenberg M et al. | Glycolytic pyruvate regulates P-Glycoprotein expression in multicellular tumor spheroids via modulation of the intracellular redox state. | 2010 | J. Cell. Biochem. | pmid:19950199 |
| North SJ et al. | Glycomics profiling of Chinese hamster ovary cell glycosylation mutants reveals N-glycans of a novel size and complexity. | 2010 | J. Biol. Chem. | pmid:19951948 |
| Johansson J et al. | Closely related isozymes of alcohol dehydrogenase. Carboxymethylation: gamma 1 gamma 1 differs widely from both beta 1 beta 1 and its equine equivalence EE. | 1991 | FEBS Lett. | pmid:1995331 |
| Sniekers YH et al. | Estrogen modulates iodoacetate-induced gene expression in bovine cartilage explants. | 2010 | J. Orthop. Res. | pmid:19953602 |
| Coombs PJ et al. | Identification of novel contributions to high-affinity glycoprotein-receptor interactions using engineered ligands. | 2010 | J. Mol. Biol. | pmid:20004209 |
| pmid:20004681 | ||||
| Armstrong SC and Ganote CE | Effects of the phospholipase inhibitor mepacrine on injury in ischemic and metabolically inhibited adult isolated myocytes. | 1991 | Am. J. Pathol. | pmid:2000934 |
| Okamoto M and Atsuta Y | Cartilage degeneration is associated with augmented chemically-induced joint pain in rats: a pilot study. | 2010 | Clin. Orthop. Relat. Res. | pmid:20013164 |
| Kempson SA et al. | Iodoacetate action on endocytic uptake of different fluid-phase markers by OK renal epithelial cells. | 1991 | Biochim. Biophys. Acta | pmid:2001415 |
| González-Teuber M et al. | Glucanases and chitinases as causal agents in the protection of Acacia extrafloral nectar from infestation by phytopathogens. | 2010 | Plant Physiol. | pmid:20023149 |
| Rogers DW et al. | Transglutaminase-mediated semen coagulation controls sperm storage in the malaria mosquito. | 2009 | PLoS Biol. | pmid:20027206 |
| Qiao YL | [Perspective of cervical cancer prevention and control in developing countries and areas]. | 2010 | Chin J Cancer | pmid:20038301 |
| pmid:20049656 | ||||
| Ziółkowski P et al. | Immunohistochemical and proteomic evaluation of nuclear ubiquitous casein and cyclin-dependent kinases substrate in invasive ductal carcinoma of the breast. | 2009 | J. Biomed. Biotechnol. | pmid:20069058 |
| Kuzinski J et al. | The vacuolar-type H-ATPase in ovine rumen epithelium is regulated by metabolic signals. | 2010 | J. Biomed. Biotechnol. | pmid:20069127 |
| Noyes PD et al. | Characterizing the in vitro hepatic biotransformation of the flame retardant BDE 99 by common carp. | 2010 | Aquat. Toxicol. | pmid:20080306 |
| Oreffo VI et al. | Diamine uptake by rat lung type II cells in vitro. | 1991 | Biochem. Pharmacol. | pmid:2009096 |
| Spencer P et al. | The identification of a structurally important cysteine residue in the glycerol dehydrogenase from Bacillus stearothermophilus. | 1991 | Biochim. Biophys. Acta | pmid:2009285 |
| Edes K et al. | JS-K, a nitric oxide prodrug, has enhanced cytotoxicity in colon cancer cells with knockdown of thioredoxin reductase 1. | 2010 | PLoS ONE | pmid:20098717 |
| Florine-Casteel K et al. | Lipid order in hepatocyte plasma membrane blebs during ATP depletion measured by digitized video fluorescence polarization microscopy. | 1991 | FASEB J. | pmid:2010060 |
| Liu H et al. | Domain-level stability of an antibody monitored by reduction, differential alkylation, and mass spectrometry analysis. | 2010 | Anal. Biochem. | pmid:20152794 |
| Calmettes G et al. | Improved energy supply regulation in chronic hypoxic mouse counteracts hypoxia-induced altered cardiac energetics. | 2010 | PLoS ONE | pmid:20174637 |
| Mann K et al. | Phosphoproteomes of Strongylocentrotus purpuratus shell and tooth matrix: identification of a major acidic sea urchin tooth phosphoprotein, phosphodontin. | 2010 | Proteome Sci | pmid:20181113 |
| pmid:20185307 | ||||
| Fiddian-Green RG and Silen W | Mechanisms of disposal of acid and alkali in rabbit duodenum. | 1975 | Am. J. Physiol. | pmid:2019 |
| Chu CR et al. | In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage. | 2010 | J Bone Joint Surg Am | pmid:20194318 |
| McGaraughty S et al. | TRPA1 modulation of spontaneous and mechanically evoked firing of spinal neurons in uninjured, osteoarthritic, and inflamed rats. | 2010 | Mol Pain | pmid:20205719 |
| Cannon JR et al. | The effects of fructose on adenosine triphosphate depletion following mitochondrial dysfunction and lethal cell injury in isolated rat hepatocytes. | 1991 | Toxicol. Appl. Pharmacol. | pmid:2020968 |
| Shirran SL and Botting CH | A comparison of the accuracy of iTRAQ quantification by nLC-ESI MSMS and nLC-MALDI MSMS methods. | 2010 | J Proteomics | pmid:20230925 |
| Hawkins HC and Freedman RB | The reactivities and ionization properties of the active-site dithiol groups of mammalian protein disulphide-isomerase. | 1991 | Biochem. J. | pmid:2025220 |
| Hawkins HC et al. | Redox properties and cross-linking of the dithiol/disulphide active sites of mammalian protein disulphide-isomerase. | 1991 | Biochem. J. | pmid:2025221 |
| SANDOW A and BRUST M | Effect of activity on the visco-elasticity of normal and iodoacetate muscles. | 1946 | Proc. Soc. Exp. Biol. Med. | pmid:20277787 |
| Lim KM et al. | Low-level mercury can enhance procoagulant activity of erythrocytes: a new contributing factor for mercury-related thrombotic disease. | 2010 | Environ. Health Perspect. | pmid:20308036 |
| Nagarathnam R et al. | Purification and properties of cysteine protease from rhizomes of Curcuma longa (Linn.). | 2010 | J. Sci. Food Agric. | pmid:20355018 |
| pmid:20356026 | ||||
| Bloom HL et al. | Statins Decrease Oxidative Stress and ICD Therapies. | 2010 | Cardiol Res Pract | pmid:20369058 |
| pmid:20392992 | ||||
| pmid:20401690 | ||||
| Cifuentes DJ et al. | Decrease in oxidative stress and histological changes induced by physical exercise calibrated in rats with osteoarthritis induced by monosodium iodoacetate. | 2010 | Osteoarthr. Cartil. | pmid:20417294 |
| Larriba MJ et al. | Novel snail1 target proteins in human colon cancer identified by proteomic analysis. | 2010 | PLoS ONE | pmid:20421926 |
| RodrÃguez E et al. | Uncoupling oxidative/energy metabolism with low sub chronic doses of 3-nitropropionic acid or iodoacetate in vivo produces striatal cell damage. | 2010 | Int. J. Biol. Sci. | pmid:20440403 |
| Kembhavi AA et al. | Clostripain: characterization of the active site. | 1991 | FEBS Lett. | pmid:2044766 |
| Zhu Y et al. | Differential gene expression in mouse retina related to regional differences in vulnerability to hyperoxia. | 2010 | Mol. Vis. | pmid:20454693 |
| Ozaki K and Ito S | Purification and properties of an acid endo-1,4-beta-glucanase from Bacillus sp. KSM-330. | 1991 | J. Gen. Microbiol. | pmid:2045781 |
| Danilo P et al. | Epinephrine-induced automaticity of canine cardiac Purkinje fibers and its relationship to the adenylate cyclase-adenosine 3',5'-monophosphate system. | 1978 | J. Pharmacol. Exp. Ther. | pmid:204768 |
| Hall AM et al. | Albumin uptake in OK cells exposed to rotenone: a model for studying the effects of mitochondrial dysfunction on endocytosis in the proximal tubule? | 2010 | Nephron Physiol | pmid:20484937 |
| Nishimura C et al. | A modulating role of mercurials-sensitive sulfhydryl groups in synaptic GABA receptor binding. | 1982 | Neurochem. Int. | pmid:20487895 |
| Chikuma T et al. | Isolation and characterization of PZ-peptidase in developing rat brain. | 1984 | Neurochem. Int. | pmid:20488031 |
| Tsai JH et al. | The protection of hepatocyte cells from the effects of oxidative stress by treatment with vitamin E in conjunction with DTT. | 2010 | J. Biomed. Biotechnol. | pmid:20490359 |
| Gigliobianco T et al. | Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. | 2010 | BMC Microbiol. | pmid:20492686 |
| Ientile R et al. | The localization of phenolic and tyrosyl ring thyroxine deiodination in rat and mouse retina. | 1985 | Neurochem. Int. | pmid:20493014 |
| Dalal P and Romani A | Adenosine triphosphate depletion by cyanide results in a Na(+)-dependent Mg(2+) extrusion from liver cells. | 2010 | Metab. Clin. Exp. | pmid:20494376 |
| pmid:20499231 | ||||
| Ivannikov MV et al. | Calcium clearance and its energy requirements in cerebellar neurons. | 2010 | Cell Calcium | pmid:20510449 |
| Castillo-Romero A et al. | Rab11 and actin cytoskeleton participate in Giardia lamblia encystation, guiding the specific vesicles to the cyst wall. | 2010 | PLoS Negl Trop Dis | pmid:20532229 |
| pmid:20538089 | ||||
| Liviac D et al. | Genotoxicity testing of three monohaloacetic acids in TK6 cells using the cytokinesis-block micronucleus assay. | 2010 | Mutagenesis | pmid:20547559 |
| Im HJ et al. | Alteration of sensory neurons and spinal response to an experimental osteoarthritis pain model. | 2010 | Arthritis Rheum. | pmid:20556813 |
| Puntel RL et al. | Mitochondrial dysfunction induced by different organochalchogens is mediated by thiol oxidation and is not dependent of the classical mitochondrial permeability transition pore opening. | 2010 | Toxicol. Sci. | pmid:20573786 |
| Ochrietor JD et al. | The 2M6 antigen is a Müller cell-specific intracellular membrane-associated protein of the sarcolemmal-membrane-associated protein family and is also TopAP. | 2010 | Mol. Vis. | pmid:20577597 |
| Kawase N et al. | Collagenolytic activity in sonic extracts of Tannerella forsythia. | 2010 | Arch. Oral Biol. | pmid:20619781 |
| Strassle BW et al. | Inhibition of osteoclasts prevents cartilage loss and pain in a rat model of degenerative joint disease. | 2010 | Osteoarthr. Cartil. | pmid:20633675 |
| Swearingen CA et al. | A short-term pharmacodynamic model for monitoring aggrecanase activity: injection of monosodium iodoacetate (MIA) in rats and assessment of aggrecan neoepitope release in synovial fluid using novel ELISAs. | 2010 | Osteoarthr. Cartil. | pmid:20633676 |
| pmid:20643199 |