Iodoacetic acid

Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.

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Introduction

To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Iodoacetic acid?

Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Iodoacetic acid

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Lung Neoplasms D008175 171 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with Iodoacetic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Iodoacetic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Iodoacetic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

What genes are associated with Iodoacetic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Iodoacetic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Iodoacetic acid

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Authors Title Published Journal PubMed Link
Serban MA and Prestwich GD Synthesis of hyaluronan haloacetates and biology of novel cross-linker-free synthetic extracellular matrix hydrogels. 2007 Biomacromolecules pmid:17696398
Lapchak PA et al. Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes. 2007 Neuroscience pmid:17942241
Krzeski P et al. Development of musculoskeletal toxicity without clear benefit after administration of PG-116800, a matrix metalloproteinase inhibitor, to patients with knee osteoarthritis: a randomized, 12-month, double-blind, placebo-controlled study. 2007 Arthritis Res. Ther. pmid:17958901
Faure G et al. Characterization of a human coagulation factor Xa-binding site on Viperidae snake venom phospholipases A2 by affinity binding studies and molecular bioinformatics. 2007 BMC Struct. Biol. pmid:18062812
Petersen SV et al. The subunit composition of human extracellular superoxide dismutase (EC-SOD) regulates enzymatic activity. 2007 BMC Biochem. pmid:17937792
Coley AM et al. Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody. 2007 PLoS Pathog. pmid:17907804
Goytia M et al. Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens. 2007 PLoS ONE pmid:17849014
Pulido JE et al. A role for excitatory amino acids in diabetic eye disease. 2007 Exp Diabetes Res pmid:17713594
Froelich JM and Reid GE Mechanisms for the proton mobility-dependent gas-phase fragmentation reactions of S-alkyl cysteine sulfoxide-containing peptide ions. 2007 J. Am. Soc. Mass Spectrom. pmid:17689096
Chen F et al. Effects of metabolic inhibition on conduction, Ca transients, and arrhythmia vulnerability in embryonic mouse hearts. 2007 Am. J. Physiol. Heart Circ. Physiol. pmid:17660398
Dray A and Read SJ Arthritis and pain. Future targets to control osteoarthritis pain. 2007 Arthritis Res. Ther. pmid:17561993
Barve RA et al. Transcriptional profiling and pathway analysis of monosodium iodoacetate-induced experimental osteoarthritis in rats: relevance to human disease. 2007 Osteoarthr. Cartil. pmid:17500014
Lew VL et al. Effects of age-dependent membrane transport changes on the homeostasis of senescent human red blood cells. 2007 Blood pmid:17456724
Neugebauer V et al. Techniques for assessing knee joint pain in arthritis. 2007 Mol Pain pmid:17391515
Beyreuther B et al. Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain. 2007 Arthritis Res. Ther. pmid:17284318
Appleton CT et al. Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis. 2007 Arthritis Res. Ther. pmid:17284317
Gover TD et al. Calcium regulation in individual peripheral sensory nerve terminals of the rat. 2007 J. Physiol. (Lond.) pmid:17095566
Kito Y and Suzuki H Effects of temperature on pacemaker potentials in the mouse small intestine. 2007 Pflugers Arch. pmid:17235578
Chen JJ et al. Oxidation of glutathione and superoxide generation by inorganic and organic selenium compounds. 2007 Biofactors pmid:18806309
Ataman IuO [Intensity of lipid peroxydation and antioxidant enzyme activity in walls of the arteries and veins in monoiodacetate intoxication]. 2007 Fiziol Zh pmid:17902371
Gatson JW and Singh M Activation of a membrane-associated androgen receptor promotes cell death in primary cortical astrocytes. 2007 Endocrinology pmid:17303658
Ivanavicius SP et al. Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF-3 and pharmacological characterisation. 2007 Pain pmid:17276007
Erdmann F et al. Hsp90-mediated inhibition of FKBP38 regulates apoptosis in neuroblastoma cells. 2007 FEBS Lett. pmid:18036348
Uryu N et al. Analgesic effects of indirect moxibustion on an experimental rat model of osteoarthritis in the knee. 2007 Acupunct Med pmid:18160928
Maher P et al. A novel approach to screening for new neuroprotective compounds for the treatment of stroke. 2007 Brain Res. pmid:17765210
Lopieńska-Biernat E et al. Trehalose catabolism enzymes in L3 and L4 larvae of Anisakis simplex. 2007 J. Parasitol. pmid:18314671
Aiedeh KM et al. Effect of ionic crosslinking on the drug release properties of chitosan diacetate matrices. 2007 J Pharm Sci pmid:17031867
Duewelhenke N et al. Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines. 2007 Antimicrob. Agents Chemother. pmid:17088489
Aromolaran AS et al. Role of glycolytically generated ATP for CaMKII-mediated regulation of intracellular Ca2+ signaling in bovine vascular endothelial cells. 2007 Am. J. Physiol., Cell Physiol. pmid:17344311
Mut PN et al. Potassium transmembrane fluxes in anoxic hepatocytes from goldfish (Carassius auratus L.). 2006 Mar-Apr Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:16298170
Wolf MB and Baynes JW The anti-cancer drug, doxorubicin, causes oxidant stress-induced endothelial dysfunction. 2006 Biochim. Biophys. Acta pmid:16337743
Gibbs ME et al. Astrocytic energy metabolism consolidates memory in young chicks. 2006 Neuroscience pmid:16750889
Ralat LA and Colman RF Identification of tyrosine 79 in the tocopherol binding site of glutathione S-transferase pi. 2006 Biochemistry pmid:17029404
Farrar RS et al. Steroid-induced cardiac contractility requires exogenous glucose, glycolysis and the sarcoplasmic reticulum in rainbow trout. 2006 J. Exp. Biol. pmid:16709913
Keravala A et al. Human, viral or mutant human IL-10 expressed after local adenovirus-mediated gene transfer are equally effective in ameliorating disease pathology in a rabbit knee model of antigen-induced arthritis. 2006 Arthritis Res. Ther. pmid:16704745
Vial D et al. Coordinate regulation of fibronectin matrix assembly by the plasminogen activator system and vitronectin in human osteosarcoma cells. 2006 Cancer Cell Int. pmid:16569238
Herrmann L et al. Biochemical and molecular characterisation of Tetrahymena thermophila extracellular cysteine proteases. 2006 BMC Microbiol. pmid:16507097
Oestergaard S et al. The utility of measuring C-terminal telopeptides of collagen type II (CTX-II) in serum and synovial fluid samples for estimation of articular cartilage status in experimental models of destructive joint diseases. 2006 Osteoarthr. Cartil. pmid:16500121
Mastbergen SC et al. Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study. 2006 Arthritis Res. Ther. pmid:16356188
Bley KR et al. RO1138452 and RO3244794: characterization of structurally distinct, potent and selective IP (prostacyclin) receptor antagonists. 2006 Br. J. Pharmacol. pmid:16331286
Riley JK et al. Phosphatidylinositol 3-kinase activity is critical for glucose metabolism and embryo survival in murine blastocysts. 2006 J. Biol. Chem. pmid:16272157
Gibbs ME et al. Inhibition of glycogenolysis in astrocytes interrupts memory consolidation in young chickens. 2006 Glia pmid:16819764
Camacho A et al. The anion channel blocker, 4,4'-dinitrostilbene-2,2'-disulfonic acid prevents neuronal death and excitatory amino acid release during glycolysis inhibition in the hippocampus in vivo. 2006 Neuroscience pmid:16920271
Shivaprasad S and Wetzel R Scanning cysteine mutagenesis analysis of Abeta-(1-40) amyloid fibrils. 2006 J. Biol. Chem. pmid:16263715
Wang XY et al. Kinetics of inactivation of phytase (phy A) during modification of histidine residue by IAA and DEP. 2006 Protein Pept. Lett. pmid:16842110
Cemeli E et al. Modulation of the cytotoxicity and genotoxicity of the drinking water disinfection byproduct lodoacetic acid by suppressors of oxidative stress. 2006 Environ. Sci. Technol. pmid:16570611
Becalski A et al. Formation of iodoacetic acids during cooking: interaction of iodized table salt with chlorinated drinking water. 2006 Food Addit Contam pmid:16982516
Rogers AB et al. Thiol-reactive compounds prevent nonspecific antibody binding in immunohistochemistry. 2006 Lab. Invest. pmid:16534499
Li S et al. Long-term storage of Clonorchis sinensis metacercariae in vitro. 2006 Parasitol. Res. pmid:16767424
Mejía-Toiber J et al. D-beta-hydroxybutyrate prevents glutamate-mediated lipoperoxidation and neuronal damage elicited during glycolysis inhibition in vivo. 2006 Neurochem. Res. pmid:17115265