MeSH term | MeSH ID | Detail |
---|---|---|
Osteoarthritis, Spine | D055013 | 2 associated lipids |
Monckeberg Medial Calcific Sclerosis | D050380 | 1 associated lipids |
Clonorchiasis | D003003 | 1 associated lipids |
Rigor Mortis | D012298 | 1 associated lipids |
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Matheny JL and Ahlquist RP | Metabolic inhibition and adrenoceptor interconversion. | 1975 | Arch Int Pharmacodyn Ther | pmid:2120 |
Takenaka F and Watanabe A | Effects of iodoacetate and anoxia on phosphate metabolism in isolated perfused rat hearts. | 1976 | Arch Int Pharmacodyn Ther | pmid:984971 |
Goodman FR and Gardiner TH | Characteristics of 45Ca uptake and efflux in rat lung slices. | 1977 | Arch Int Pharmacodyn Ther | pmid:603308 |
Stout MA et al. | Effect of metabolic inhibitors on 45Ca fluxes and ATP content of myelinated nerve. | 1980 | Arch Int Pharmacodyn Ther | pmid:6966488 |
Costeseque R et al. | Polysulphated polysaccharides: an in vitro study of their effects on proteoglycan biosynthesis by articular chondrocytes. | 1986 | Arch Int Pharmacodyn Ther | pmid:2429628 |
ISSEKUTZ B et al. | Tissue metabolism and peripheral circulation. I. Effect of iodoacetic acid on the metabolism of muscles "in vivo". | 1951 | Arch Int Physiol | pmid:14857870 |
ISSEKUTZ B et al. | Tissue metabolism and peripheral circulation. II. Effect of iodoacetic acid on peripheral circulation. | 1951 | Arch Int Physiol | pmid:14857871 |
Booden T et al. | Uptake of selected pyrimidines by axenically grown Entamoeba histolytica. | 1978 | Arch Invest Med (Mex) | pmid:211944 |
Karduck A et al. | Morphological and physiological findings on hair cells with impaired metabolism (nitrogen, monoiodoacetate) in Caiman crocodilus with reference to sudden deafness. | 1976 | Arch Otorhinolaryngol | pmid:989728 |
Urist MR et al. | A chemosterilized antigen-extracted autodigested alloimplant for bone banks. | 1975 | Arch Surg | pmid:1096848 |
Shieh JH et al. | Purification and characterization of human colony-stimulating factor 1 from human pancreatic carcinoma (MIA PaCa-2) cells. | 1987 | Arch. Biochem. Biophys. | pmid:3545083 |
Nagasaka Y et al. | Microsomal glutathione-dependent protection against lipid peroxidation acts through a factor other than glutathione peroxidase and glutathione S-transferase in rat liver. | 1989 | Arch. Biochem. Biophys. | pmid:2774585 |
Kembhavi AA et al. | The two cysteine endopeptidases of legume seeds: purification and characterization by use of specific fluorometric assays. | 1993 | Arch. Biochem. Biophys. | pmid:8512309 |
Bubis J et al. | Chemical modification of transducin with iodoacetic acid: transducin-alpha carboxymethylated at Cys(347) allows transducin binding to Light-activated rhodopsin but prevents its release in the presence of GTP. | 2001 | Arch. Biochem. Biophys. | pmid:11697851 |
Chen LY et al. | Deoxyribonuclease of Syncephalastrum racemosum--enzymatic properties and molecular structure. | 1993 | Arch. Biochem. Biophys. | pmid:8489265 |
Konishi K and Fujioka M | Reversible inactivation of recombinant rat liver guanidinoacetate methyltransferase by glutathione disulfide. | 1991 | Arch. Biochem. Biophys. | pmid:1898065 |
Thampy KG and Barnes EM | Adenosine transport by cultured glial cells from chick embryo brain. | 1983 | Arch. Biochem. Biophys. | pmid:6824327 |
Sterchi EE et al. | N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase: a metalloendopeptidase of the human intestinal microvillus membrane which degrades biologically active peptides. | 1988 | Arch. Biochem. Biophys. | pmid:3261961 |
Grigor MR | Multiple molecular forms of rat mammary glucose-6-phosphate dehydrogenase: proposed role in turnover of the enzyme. | 1984 | Arch. Biochem. Biophys. | pmid:6703713 |
Bernström K et al. | Metabolism of leukotriene E4 to 5-hydroxy-6-mercapto7,9-trans-11,14-cis-eicosatetraenoic acid by microfloral cysteine-conjugate beta-lyase and rat cecum contents. | 1989 | Arch. Biochem. Biophys. | pmid:2556967 |
Blum J and Fridovich I | Inactivation of glutathione peroxidase by superoxide radical. | 1985 | Arch. Biochem. Biophys. | pmid:2992378 |
Bicsak TA and Harper E | Chemical and kinetic characterization of tadpole back skin collagenase. | 1985 | Arch. Biochem. Biophys. | pmid:2996432 |
Park YC and Goodman WG | Analysis and modification of thiols in the hemolymph juvenile hormone binding protein of Manduca sexta. | 1993 | Arch. Biochem. Biophys. | pmid:8470889 |
Gupta NK and Glantz MD | Isolation and characterization of human liver guanine deaminase. | 1985 | Arch. Biochem. Biophys. | pmid:3966794 |
Malinowski K and Manski W | Modification of alpha-crystallin subunit chains and formation of alpha-neoprotein molecules: role of SH groups. | 1984 | Arch. Biochem. Biophys. | pmid:6380411 |
Miller RM et al. | Phosphorylase and creatine kinase modification by thiol-disulfide exchange and by xanthine oxidase-initiated S-thiolation. | 1990 | Arch. Biochem. Biophys. | pmid:2106288 |
Khowala S and Sengupta S | Purification and properties of an endo-alpha-mannan hydrolase from the mushroom Volvariella volvacea. | 1985 | Arch. Biochem. Biophys. | pmid:4041163 |
Syvertsen C and McKinley-McKee JS | Ionization-linked cooperative interactions in the active site of horse liver alcohol dehydrogenase. | 1983 | Arch. Biochem. Biophys. | pmid:6344794 |
Krieger TJ and Miziorko HM | Spinach leaf ribulose-5-phosphate kinase: examination of sulfhydryls by chemical modification and spin-labeling. | 1987 | Arch. Biochem. Biophys. | pmid:3038027 |
Chaudiere J and Tappel AL | Purification and characterization of selenium-glutathione peroxidase from hamster liver. | 1983 | Arch. Biochem. Biophys. | pmid:6227287 |
Conradt H et al. | Pyruvate formate-lyase (inactive form) and pyruvate formate-lyase activating enzyme of Escherichia coli: isolation and structural properties. | 1984 | Arch. Biochem. Biophys. | pmid:6364987 |
Syvertsen C and McKinley-McKee JS | Binding of ligands to the catalytic zinc ion in horse liver alcohol dehydrogenase. | 1984 | Arch. Biochem. Biophys. | pmid:6364988 |
Cittadini A and Scarpa A | Intracellular Mg2+ homeostasis of Ehrlich ascites tumor cells. | 1983 | Arch. Biochem. Biophys. | pmid:6416179 |
Scott-Ennis RJ and Noltmann EA | Differential response of cysteine residues in pig muscle phosphoglucose isomerase to seven sulfhydryl-modifying reagents. | 1985 | Arch. Biochem. Biophys. | pmid:4004250 |
Mukerji SK | Studies on the rabbit proacrosin-acrosin system. | 1984 | Arch. Biochem. Biophys. | pmid:6424572 |
RodrÃguez SB et al. | Cysteine 351 is an essential nucleophile in catalysis by Porphyromonas gingivalis peptidylarginine deiminase. | 2010 | Arch. Biochem. Biophys. | pmid:20850413 |
Calviello G et al. | Further observations on the effect of calcium ionophores on ascites tumor cells. | 1987 | Arch. Biochem. Biophys. | pmid:3688885 |
Rioux CR et al. | Anthranilate-promoted iron uptake in Rhizobium leguminosarum. | 1986 | Arch. Biochem. Biophys. | pmid:3729414 |
Shroyer LA and Varandani PT | Purification and characterization of a rat liver cytosol neutral thiol peptidase that degrades glucagon, insulin, and isolated insulin A and B chains. | 1985 | Arch. Biochem. Biophys. | pmid:3881083 |
Huang YC et al. | Identification of the subunits and target peptides of pig heart NAD-specific isocitrate dehydrogenase modified by the affinity label 8-(4-bromo-2,3-dioxobutylthio)NAD. | 1997 | Arch. Biochem. Biophys. | pmid:9390193 |
Dransfield DT and Aprille JR | The influence of hypoxia and anoxia on distribution of adenine nucleotides in isolated hepatocytes. | 1994 | Arch. Biochem. Biophys. | pmid:8053677 |
Xu W et al. | Identification of critical positive charges in XIP, the Na/Ca exchange inhibitory peptide. | 1997 | Arch. Biochem. Biophys. | pmid:9169015 |
Tisljar U and Barrett AJ | Purification and characterization of Pz-peptidase from rabbit muscle. | 1989 | Arch. Biochem. Biophys. | pmid:2673041 |
Duff SM et al. | An engineered change in the L-malate sensitivity of a site-directed mutant of sorghum phosphoenolpyruvate carboxylase: the effect of sequential mutagenesis and S-carboxymethylation at position 8. | 1993 | Arch. Biochem. Biophys. | pmid:8215415 |
Clogston CL et al. | Disulfide structures of human interleukin-6 are similar to those of human granulocyte colony stimulating factor. | 1989 | Arch. Biochem. Biophys. | pmid:2472117 |
Park EM and Thomas JA | Reduction of protein mixed disulfides (dethiolation) by Escherichia coli thioredoxin: a study with glycogen phosphorylase b and creatine kinase. | 1989 | Arch. Biochem. Biophys. | pmid:2500063 |
Wright SK et al. | Mechanistic studies on malate dehydrogenase from Escherichia coli. | 1995 | Arch. Biochem. Biophys. | pmid:7646053 |
Lu HS et al. | Disulfide and secondary structures of recombinant human granulocyte colony stimulating factor. | 1989 | Arch. Biochem. Biophys. | pmid:2463792 |
Crouzoulon G | [Kinetic properties of the fructose influx across the brush border of the rat jejunum. Effects of a diet rich in fructose]. | 1978 | Arch. Int. Physiol. Biochim. | pmid:84551 |
Garnett HM | Energy-dependent accumulation of Ca2+ by human embryonic lung fibroblasts. | 1979 | Arch. Int. Physiol. Biochim. | pmid:93434 |