MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin B 6 Deficiency | D026681 | 10 associated lipids |
Monckeberg Medial Calcific Sclerosis | D050380 | 1 associated lipids |
Osteophyte | D054850 | 2 associated lipids |
Osteoarthritis, Spine | D055013 | 2 associated lipids |
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Izumi M et al. | Local ASIC3 modulates pain and disease progression in a rat model of osteoarthritis. | 2012 | J. Biomed. Sci. | pmid:22909215 |
Wei X et al. | Drinking water disinfection byproduct iodoacetic acid induces tumorigenic transformation of NIH3T3 cells. | 2013 | Environ. Sci. Technol. | pmid:23641915 |
Nan Y et al. | Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat. | 2013 | Sci China Life Sci | pmid:23657794 |
More AS et al. | Effect of iNOS inhibitor S-methylisothiourea in monosodium iodoacetate-induced osteoathritic pain: implication for osteoarthritis therapy. | 2013 | Pharmacol. Biochem. Behav. | pmid:23287799 |
La Porta C et al. | Role of CB1 and CB2 cannabinoid receptors in the development of joint pain induced by monosodium iodoacetate. | 2013 | Pain | pmid:23199705 |
Shao H et al. | Intra-articular injection of xanthan gum reduces pain and cartilage damage in a rat osteoarthritis model. | 2013 | Carbohydr Polym | pmid:23399228 |
Cialdai C et al. | Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats. | 2013 | Eur. J. Pharmacol. | pmid:23891968 |
Pals J et al. | Human cell toxicogenomic analysis linking reactive oxygen species to the toxicity of monohaloacetic acid drinking water disinfection byproducts. | 2013 | Environ. Sci. Technol. | pmid:24050308 |
Dhaneshwar S and Patil D | Chondromodulating chimeric prodrugs of diacetylrhein: synthesis and evaluation in monoiodoacetate-induced hyperalgesia. | 2013 | Med Chem | pmid:22920092 |
Liu X et al. | An optimized analytical method for the simultaneous detection of iodoform, iodoacetic acid, and other trihalomethanes and haloacetic acids in drinking water. | 2013 | PLoS ONE | pmid:23613747 |