MeSH term | MeSH ID | Detail |
---|---|---|
Vitamin B 6 Deficiency | D026681 | 10 associated lipids |
Monckeberg Medial Calcific Sclerosis | D050380 | 1 associated lipids |
Osteophyte | D054850 | 2 associated lipids |
Osteoarthritis, Spine | D055013 | 2 associated lipids |
Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-.
To understand associated biological information of Iodoacetic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Iodoacetic acid is suspected in Photoreceptor degeneration, Post MI and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with Iodoacetic acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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pmid:12097793 | ||||
pmid:12093093 | ||||
Lawrence CL et al. | Effect of metabolic inhibition on glimepiride block of native and cloned cardiac sarcolemmal K(ATP) channels. | 2002 | Br. J. Pharmacol. | pmid:12086984 |
Rodrigo GC et al. | Dinitrophenol pretreatment of rat ventricular myocytes protects against damage by metabolic inhibition and reperfusion. | 2002 | J. Mol. Cell. Cardiol. | pmid:12056859 |
Vecchiarelli A et al. | Antibody to Cryptococcus neoformans capsular glucuronoxylomannan promotes expression of interleukin-12Rbeta2 subunit on human T cells in vitro through effects mediated by antigen-presenting cells. | 2002 | Immunology | pmid:12047756 |
Matsuki N et al. | Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia. | 2002 | J. Vet. Med. Sci. | pmid:12014580 |
Maithal K et al. | Inhibition of plasmodium falciparum triose-phosphate isomerase by chemical modification of an interface cysteine. Electrospray ionization mass spectrometric analysis of differential cysteine reactivities. | 2002 | J. Biol. Chem. | pmid:12006590 |
Mizuno Y et al. | Cysteine synthase of an extremely thermophilic bacterium, Thermus thermophilus HB8. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12005048 |
pmid:11926296 | ||||
pmid:11904218 | ||||
Lasch J | Fluorescence and chemical reactivity as empirical indices of matrix-induced alterations in immobilized enzymes. | 1975 | Acta Biol. Med. Ger. | pmid:1189829 |
pmid:11893026 | ||||
pmid:11889583 | ||||
Sugisawa T and Hoshino T | Purification and properties of membrane-bound D-sorbitol dehydrogenase from Gluconobacter suboxydans IFO 3255. | 2002 | Biosci. Biotechnol. Biochem. | pmid:11866120 |
Edwards RH et al. | Metabolic changes associated with the slowing of relaxation in fatigued mouse muscle. | 1975 | J. Physiol. (Lond.) | pmid:1185665 |
Abdo MA et al. | Inhibitors of caspase homologues suppress an apoptotic phenotype in cultured rabbit corpora lutea. | 2001 | Reprod. Fertil. Dev. | pmid:11833936 |
Zółtowska K | Purification and characterization of alpha-amylases from the intestine and muscle of ascaris suum (Nematoda). | 2001 | Acta Biochim. Pol. | pmid:11833785 |
Marbach EP et al. | Sodium iodoacetate as an antiglycolytic agent in blood samples. | 1975 | Clin. Chem. | pmid:1183004 |
Siflinger A et al. | Uptake of 125I albumin by the endothelial surface of the isolated dog common carotid artery: effect of certain physical factors and metabolic inhibitors. | 1975 | Cardiovasc. Res. | pmid:1182724 |
Jaspers HT and van Steveninck J | Transport-associated phosphorylation of 2-deoxy-D-glucose in Saccharomyces fragilis. | 1975 | Biochim. Biophys. Acta | pmid:1182170 |
Takahashi S et al. | Substrate-dependence of reduction of MTT: a tetrazolium dye differs in cultured astroglia and neurons. | 2002 | Neurochem. Int. | pmid:11821152 |
Janusz MJ et al. | Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors. | 2001 | Osteoarthr. Cartil. | pmid:11795995 |
Wudayagiri R et al. | Isolation and characterization of a novel lepidopteran-selective toxin from the venom of South Indian red scorpion, Mesobuthus tamulus. | 2001 | BMC Biochem. | pmid:11782289 |
Petitpierre-Gabathuler MP and Ryser HJ | Cellular uptake of soluble and aggregated ferritin: distinction between pinocytosis and phagocytosis. | 1975 | J. Cell. Sci. | pmid:1176545 |
Bogliolo M et al. | Alternative metabolic pathways for energy supply and resistance to apoptosis in Fanconi anaemia. | 2002 | Mutagenesis | pmid:11752230 |
Rudnick G and Abeles RH | Reaction mechanism and structure of the active site of proline racemase. | 1975 | Biochemistry | pmid:1174513 |
Merker MP et al. | Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells. | 2002 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:11741813 |
Massaro D | In vivo protein secretion by lung. Evidence for active secretion and interspecies differences. | 1975 | J. Clin. Invest. | pmid:1173812 |
Kohlstock UM et al. | Cys359 of GrdD is the active-site thiol that catalyses the final step of acetyl phosphate formation by glycine reductase from Eubacterium acidaminophilum. | 2001 | Eur. J. Biochem. | pmid:11737196 |
Basselin-Eiweida M and Kaneshiro ES | Detection of two distinct transporter systems for 2-deoxyglucose uptake by the opportunistic pathogen Pneumocystis carinii. | 2001 | Biochim. Biophys. Acta | pmid:11718673 |
Bubis J et al. | Chemical modification of transducin with iodoacetic acid: transducin-alpha carboxymethylated at Cys(347) allows transducin binding to Light-activated rhodopsin but prevents its release in the presence of GTP. | 2001 | Arch. Biochem. Biophys. | pmid:11697851 |
pmid:11695393 | ||||
pmid:11693549 | ||||
Guo Z et al. | Iodoacetate protects hippocampal neurons against excitotoxic and oxidative injury: involvement of heat-shock proteins and Bcl-2. | 2001 | J. Neurochem. | pmid:11677264 |
Walker WS and Demus A | Antibody-dependent cytolysis of chicken erythrocytes by an in vitro-established line of mouse peritoneal macrophages. | 1975 | J. Immunol. | pmid:1167563 |
Nijweide PJ and van der Plas A | Regulation of calcium transport in isolated periosteal cells, effects of hormones and metabolic inhibitors. | 1979 | Calcif. Tissue Int. | pmid:116755 |
Tavazzi B et al. | Oxidative stress induces impairment of human erythrocyte energy metabolism through the oxygen radical-mediated direct activation of AMP-deaminase. | 2001 | J. Biol. Chem. | pmid:11675377 |
Ayala E and Canonico PG | Aminoisobutyric acid transport in primary cultures of normal adult rat hepatocytes. | 1975 | Proc. Soc. Exp. Biol. Med. | pmid:1166067 |
Zervos C and Adams E | Hydroxyproline-2-epimerase of Pseudomonas: active-site peptides. | 1975 | Mol. Cell. Biochem. | pmid:1165763 |
pmid:11640901 | ||||
pmid:11594466 | ||||
Lawrence CL et al. | The KATP channel opener diazoxide protects cardiac myocytes during metabolic inhibition without causing mitochondrial depolarization or flavoprotein oxidation. | 2001 | Br. J. Pharmacol. | pmid:11588107 |
Leach RM et al. | Divergent roles of glycolysis and the mitochondrial electron transport chain in hypoxic pulmonary vasoconstriction of the rat: identity of the hypoxic sensor. | 2001 | J. Physiol. (Lond.) | pmid:11579170 |
pmid:11521884 | ||||
Delgado EF et al. | Properties of myofibril-bound calpain activity in longissimus muscle of callipyge and normal sheep. | 2001 | J. Anim. Sci. | pmid:11518218 |
Boja ES and Fales HM | Overalkylation of a protein digest with iodoacetamide. | 2001 | Anal. Chem. | pmid:11510821 |
Trinchieri G and De Marchi M | Antibody-dependent cell-mediated cytotoxicity in humans. II. Energy requirement. | 1975 | J. Immunol. | pmid:1151059 |
Kishida F et al. | A type kappa Bence Jones protein containing a cysteinyl residue in the variable region. | 1975 | J. Biochem. | pmid:1150631 |
Okamoto K et al. | ATP from glycolysis is required for normal sodium homeostasis in resting fast-twitch rodent skeletal muscle. | 2001 | Am. J. Physiol. Endocrinol. Metab. | pmid:11500303 |
Li LC and Cosgrove DJ | Grass group I pollen allergens (beta-expansins) lack proteinase activity and do not cause wall loosening via proteolysis. | 2001 | Eur. J. Biochem. | pmid:11488915 |